Research output per year
Research output per year
Research output
- 1 - 50 out of 1,098 results
Search results
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2025
Effect of fluid flow-induced shear stress on the behavior of synovial fibroblasts in a bioinspired synovium-on-chip model
Piluso, S., Li, Y., Texeira, L. M., Padmanaban, P., Rouwkema, J., Leijten, J., van Weeren, R., Karperien, M. & Malda, J., Jun 2025, In: Journal of Cartilage and Joint Preservation. 5, 2, 100233.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)26 Downloads (Pure) -
High-Throughput Single-Cell Analysis of Local Nascent Protein Deposition in 3D Microenvironments via Extracellular Protein Identification Cytometry (EPIC)
Meteling, M., Johnbosco, C., Wolfel, A., Conceição, F., Govindaraj, K., Teixeira, L. M. & Leijten, J., 12 Feb 2025, In: Advanced materials. 37, 6, 2415981.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)45 Downloads (Pure) -
Porous photo-crosslinked hybrid networks based on poly(trimethylene carbonate-co-ε-caprolactone) and recombinant human-like collagen
van Bochove, B., Warmink, L., Ankoné, M. J. K., Grijpma, D. W. & Poot, A. A., Feb 2025, In: Biomaterials Advances. 167, 214106.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile65 Downloads (Pure) -
Porous polytrimethylenecarbonate scaffolds: Design considerations and porosity modulation techniques
Jurczak, K. M., Zhang, R., Hinrichs, W. L. J., Grijpma, D. W., Schuurmann, R. C. L., de Vries, J.-P. P. M. & van Rijn, P., Feb 2025, In: Materials & Design. 250, 113588.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Citations (Scopus)40 Downloads (Pure) -
Production of Hydrophobic Microparticles at Safe-To-Inject Sizes for Intravascular Administration
Gomes, F. L., Conceição, F., Teixeira, L. M., Leijten, J. & Jonkheijm, P., 6 Jan 2025, In: Pharmaceutics. 17, 1, 64.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)9 Downloads (Pure) -
Sex-stratified osteochondral organ-on-chip model reveals sex-specific responses to inflammatory stimulation
Pereira Dos Santos Conceição, F., Meneses, J., Lebre, F., Becker, M., Araújo-Gomes, N., Vos, R., Ribeiro, A. R., Alfaro-Moreno, E., Leijten, J. & Moreira Teixeira, L., Jun 2025, In: Materials Today Bio. 32, 13 p., 101728.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Downloads (Pure) -
Surface modification of extracellular vesicles with polyoxazolines to enhance their plasma stability and tumor accumulation
Simon, L., Constanzo, J., Terraza-Aguirre, C., Ibn Elfekih, Z., Berthelot, J., Benkhaled, B. T., Haute, T., Pednekar, K., Clark, K., Emerson, S. J., Atis, S., Benedetti, C., Langlois, S., Marquant, A., Prakash, J., Wang, A., Devoisselle, J. M., Montier, T., Djouad, F. & Pouget, J. P. & 2 others, , Feb 2025, In: Biomaterials. 313, 19 p., 122748.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile12 Citations (Scopus)1 Downloads (Pure) -
2024
3D printing of porous poly(ε-caprolactone)-poly(trimethylene carbonate)-poly(ε-caprolactone) triblock copolymers and nano-apatite composite structures
Güney, A., Kernebeck, L. & Grijpma, D. W., Apr 2024, In: Express polymer letters. 18, 4, p. 349-358 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)99 Downloads (Pure) -
Guiding organs-on-chips towards applications: a balancing act between integration of advanced technologies and standardization
Meneses, J., Pereira Dos Santos Conceição, F., van der Meer, A., de Wit, S. & Moreira Teixeira Leijten, L. S., 15 May 2024, In: Frontiers in Lab on a Chip Technologies. 3, 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile51 Downloads (Pure) -
In Vitro and In Vivo Degradation of Photo‐Crosslinked Poly(Trimethylene Carbonate‐co‐ε‐Caprolactone) Networks
van Bochove, B., Rongen, J. J., Hannink, G., Seppälä, J. V., Poot, A. A. & Grijpma, D. W., Mar 2024, In: Macromolecular bioscience. 24, 3, 2300364.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile5 Citations (Scopus)84 Downloads (Pure) -
Polymeric nanofiber leveraged co-delivery of anti-stromal PAK1 inhibitor and paclitaxel enhances therapeutic effects in stroma-rich 3D spheroid models
M.R.H. Mostafa, A., Petrai, O., Poot, A. A. & Prakash, J., 10 May 2024, In: International journal of pharmaceutics. 656, 124078.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile4 Citations (Scopus)84 Downloads (Pure) -
Strontium-Substituted Nanohydroxyapatite Containing Biodegradable 3D Printed Composite Scaffolds for Bone Regeneration
Shaikh, S., Mehrotra, S., van Bochove, B., Teotia, A., Singh, P., Laurén, I., Lindfors, N. C., Seppälä, J. V. & Kumar, A., 27 Nov 2024, In: ACS Applied Materials and Interfaces. 16, 47, p. 65378–65393 16 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus)18 Downloads (Pure) -
Targeted nanomedicine for reprogramming the tumor innate immune system: From bench to bedside
Pednekar, K., Minnee, J., de Vries, I. J. M. & Prakash, J., Nov 2024, In: European journal of pharmaceutics and biopharmaceutics. 204, 13 p., 114510.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)111 Downloads (Pure) -
Understanding glioblastoma stromal barriers against NK cell attack using tri-culture 3D spheroid model
Heinrich, M. A., Huynh, N. T., Heinrich, L. & Prakash, J., 15 Feb 2024, In: Heliyon. 10, 3, e24808.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile4 Citations (Scopus)90 Downloads (Pure) -
2023
A culture model to analyze the acute biomaterial-dependent reaction of human primary neutrophils in vitro
Wesdorp, M. A., Schwab, A., Bektas, E. I., Narcisi, R., Eglin, D., Stoddart, M. J., Van Osch, G. J. V. M. & D'Este, M., Feb 2023, In: Bioactive Materials. 20, p. 627-637 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile9 Citations (Scopus)94 Downloads (Pure) -
Aggregation and Gelation Behavior of Stereocomplexed Four-Arm PLA-PEG Copolymers Containing Neutral or Cationic Linkers
Signori, F., Wennink, J. W. H., Bronco, S., Feijen, J., Karperien, M., Bizzarri, R. & Dijkstra, P. J., Feb 2023, In: International journal of molecular sciences. 24, 4, 3327.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile5 Citations (Scopus)116 Downloads (Pure) -
Alginate chitosan microbeads and thermos-responsive hyaluronic acid hydrogel for phage delivery
Rotman, S. G., Post, V., Foster, A. L., Lavigne, R., Wagemans, J., Trampuz, A., Moreno, M. G., Metsemakers, W. J., Grijpma, D. W., Richards, R. G., Eglin, D. & Moriarty, T. F., Jan 2023, In: Journal of drug delivery science and technology. 79, 103991.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile22 Citations (Scopus)356 Downloads (Pure) -
Bioengineered Kidney Tubules Efficiently Clear Uremic Toxins in Experimental Dialysis Conditions
Faria, J., Ahmed, S., Stamatialis, D., Verhaar, M. C., Masereeuw, R., Gerritsen, K. G. F. & Mihăilă, S. M., Aug 2023, In: International journal of molecular sciences. 24, 15, 15 p., 12435.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus)38 Downloads (Pure) -
Bioluminescence imaging on-chip platforms for non-invasive high-content bioimaging
Araújo-Gomes, N., Zambito, G., Johnbosco, C., Calejo, I., Leijten, J., Löwik, C., Karperien, M., Mezzanotte, L. & Teixeira, L. M., 1 Oct 2023, In: Biosensors and Bioelectronics. 237, 115510.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile12 Citations (Scopus)159 Downloads (Pure) -
Current status and advances in esophageal drug delivery technology: influence of physiological, pathophysiological and pharmaceutical factors
Lim, A. W., Talley, N. J., Walker, M. M., Storm, G. & Hua, S., 2023, In: Drug Delivery. 30, 1, 2219423.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile17 Citations (Scopus)104 Downloads (Pure) -
Endotoxin contamination alters macrophage-cancer cell interaction and therapeutic efficacy in pre-clinical 3D in vitro models
Heinrich, M. A., Heinrich, L., Ankone, M. J. K., Vergauwen, B. & Prakash, J., Jan 2023, In: Biomaterials Advances. 144, 213220.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile9 Citations (Scopus)192 Downloads (Pure) -
Enzymatic post-crosslinking of printed hydrogels of methacrylated gelatin and tyramine-conjugated 8-arm poly(ethylene glycol) to prepare interpenetrating 3D network structures
Liang, J., Wang, Z., Poot, A. A., Grijpma, D. W., Dijkstra, P. J. & Wang, R., 2023, In: International Journal of Bioprinting. 9, 5Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile5 Citations (Scopus)137 Downloads (Pure) -
Evaluation of paclitaxel-loaded polymeric nanoparticles in 3D tumor model: impact of tumor stroma on penetration and efficacy
Priwitaningrum, D. L., Pednekar, K., Gabriël, A. V., Varela-Moreira, A. A., Gac, S. L., Vellekoop, I., Storm, G., Hennink, W. E. & Prakash, J., May 2023, In: Drug delivery and translational research. 13, 5, p. 1470-1483 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile9 Citations (Scopus)123 Downloads (Pure) -
Injectable liposomal docosahexaenoic acid alleviates atherosclerosis progression and enhances plaque stability
Chong, S. Y., Wang, X., van Bloois, L., Huang, C., Syeda, N. S., Zhang, S., Ting, H. J., Nair, V., Lin, Y., Lou, C. K. L., Benetti, A. A., Yu, X., Lim, N. J. Y., Tan, M. S., Lim, H. Y., Lim, S. Y., Thiam, C. H., Looi, W. D., Zharkova, O. & Chew, N. W. S. & 9 others, , Aug 2023, In: Journal of controlled release. 360, p. 344-364 21 p.Research output: Contribution to journal › Article › Academic › peer-review
22 Citations (Scopus) -
In Vivo Detection of Circulating Cancer-Associated Fibroblasts in Breast Tumor Mouse Xenograft: Impact of Tumor Stroma and Chemotherapy
Lu, T., Oomens, L., Terstappen, L. W. M. M. & Prakash, J., Feb 2023, In: Cancers. 15, 4, 1127.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile6 Citations (Scopus)114 Downloads (Pure) -
Microarchitectural mimicking of stroma-induced vasculature compression in pancreatic tumors using a 3D engineered model
Heinrich, M. A., Uboldi, I., Kuninty, P. R., Ankone, M. J. K., van Baarlen, J., Zhang, Y. S., Jain, K. & Prakash, J., Apr 2023, In: Bioactive Materials. 22, p. 18-33 16 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile11 Citations (Scopus)146 Downloads (Pure) -
Microbubble-Assisted Ultrasound for Drug Delivery to the Retina in an Ex Vivo Eye Model
Rousou, C., van Kronenburg, N., Sonnen, A. F. P., van Dijk, M., Moonen, C., Storm, G., Mastrobattista, E. & Deckers, R., Apr 2023, In: Pharmaceutics. 15, 4, 14 p., 1220.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile6 Citations (Scopus)68 Downloads (Pure) -
Microfluidic-based skin-on-chip systems for safety assessment of nanomaterials
Costa, S., Vilas-Boas, V., Lebre, F., Granjeiro, J. M., Catarino, C. M., Moreira teixeira, L., Loskill, P., Alfaro-Moreno, E. & Ribeiro, R. A., 1 Oct 2023, In: Trends in biotechnology. 41, 10, p. 1282-1298 17 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile15 Citations (Scopus)114 Downloads (Pure) -
Modulating design parameters to drive cell invasion into hydrogels for osteochondral tissue formation
Schwab, A., Wesdorp, M. A., Xu, J., Abinzano, F., Loebel, C., Falandt, M., Levato, R., Eglin, D., Narcisi, R., Stoddart, M. J., Malda, J., Burdick, J. A., D'Este, M. & van Osch, G. J. V. M., 4 Sept 2023, In: Journal of orthopaedic translation. 41, p. 42-53 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile10 Citations (Scopus)9 Downloads (Pure) -
Physicochemical Characterization and Immunomodulatory Activity of Polyelectrolyte Multilayer Coatings Incorporating an Exopolysaccharide from Bifidobacterium longum
Bagnol, R., Siverino, C., Barnier, V., O’Mahony, L., Grijpma, D. W., Eglin, D. & Moriarty, T. F., 11 Dec 2023, In: Biomacromolecules. 24, 12, p. 5589-5604 16 p.Research output: Contribution to journal › Article › Academic › peer-review
1 Citation (Scopus) -
Platelets interact with CD169+ macrophages and cDC1 and enhance liposome-induced CD8+ T cell responses
Grabowska, J., Léopold, V., Olesek, K., Nijen Twilhaar, M. K., Affandi, A. J., Brouwer, M. C., Verschoor, A., Van Kooten, C., van Kooyk, Y., Storm, G. & Den Haan, J. M. M., 2023, In: Frontiers in Immunology. 14, 16 p., 1290272.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile8 Citations (Scopus)80 Downloads (Pure) -
Preclinical validation of a new hybrid molecule loaded in liposomes for melanoma management
Pinho, J. O., Matias, M., Marques, V., Eleutério, C., Fernandes, C., Gano, L., Amaral, J. D., Mendes, E., Perry, M. J., Moreira, J. N., Storm, G., Francisco, A. P., Rodrigues, C. M. P. & Gaspar, M. M., Jan 2023, In: Biomedicine and Pharmacotherapy. 157, 114021.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile15 Citations (Scopus)62 Downloads (Pure) -
Repositioning the antihistamine ebastine as an intracellular siRNA delivery enhancer
Muntean, C., Blondeel, E., Harinck, L., Pednekar, K., Prakash, J., De Wever, O., Chain, J. L., De Smedt, S. C., Remaut, K. & Raemdonck, K., 25 Sept 2023, In: International journal of pharmaceutics. 644, 123348.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile10 Citations (Scopus)128 Downloads (Pure) -
Repurposing Tamoxifen for Tumor Microenvironment Priming and Enhanced Tumor-Targeted Drug Delivery
Biancacci, I., De Santis, D., Rama, E., Benderski, K., Momoh, J., Pohlberger, R., Moeckel, D., Kaps, L., Rijcken, C. J. F., Prakash, J., Thewissen, M., Kiessling, F., Shi, Y., Peña, Q., Sofias, A. M., Consolino, L. & Lammers, T., Nov 2023, In: Advanced Therapeutics. 6, 11, 2300098.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)91 Downloads (Pure) -
2022
3D Lung-on-Chip Model Based on Biomimetically Microcurved Culture Membranes
Baptista, D., Moreira Teixeira, L., Barata, D., Tahmasebi Birgani, Z., King, J., van Riet, S., Pasman, T., Poot, A. A., Stamatialis, D., Rottier, R. J., Hiemstra, P. S., Carlier, A., van Blitterswijk, C., Habibović, P., Giselbrecht, S. & Truckenmüller, R., 13 Jun 2022, In: ACS Biomaterials Science and Engineering. 8, 6, p. 2684-2699 16 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile59 Citations (Scopus)331 Downloads (Pure) -
Biocompatibility and degradation comparisons of four biodegradable copolymeric osteosynthesis systems used in maxillofacial surgery: A goat model with four years follow-up
Gareb, B., van Bakelen, N. B., Driessen, L., Buma, P., Kuipers, J., Grijpma, D. W., Vissink, A., Bos, R. R. M. & van Minnen, B., Nov 2022, In: Bioactive Materials. 17, p. 439-456 18 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile8 Citations (Scopus)189 Downloads (Pure) -
Cancer immune therapy using engineered ‛tail-flipping’ nanoliposomes targeting alternatively activated macrophages
Kuninty, P. R., Binnemars-Postma, K., Jarray, A., Pednekar, K. P., Heinrich, M. A., Pijffers, H. J., ten Hoopen, H., Storm, G., van Hoogevest, P., den Otter, W. K. & Prakash, J., Dec 2022, In: Nature communications. 13, 1, 4548.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile28 Citations (Scopus)145 Downloads (Pure) -
Enhancing Cellular Internalization of Single-Chain Polymer Nanoparticles via Polyplex Formation
Hamelmann, N. M., Uijttewaal, S., Hujaya, S. D. & Paulusse, J. M. J., 12 Dec 2022, In: Biomacromolecules. 23, 12, p. 5036-5042 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile9 Citations (Scopus)114 Downloads (Pure) -
Hybrid Hydrogels Based on Methacrylate-Functionalized Gelatin (GelMA) and Synthetic Polymers
Liang, J., Dijkstra, P. J., Poot, A. A. & Grijpma, D. W., 2022, In: Biomedical Materials & Devices. 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile16 Citations (Scopus)145 Downloads (Pure) -
Hybrid Networks of Hyaluronic Acid and Poly(trimethylene carbonate) for Tissue Regeneration
Gielen, A. M. C., Ankone, M., Grijpma, D. W. & Poot, A. A., 23 Nov 2022, In: Biomacromolecules. 24, 10, p. 4366–4374Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile9 Citations (Scopus)129 Downloads (Pure) -
Impact of endotoxins on bioengineered tissues and models
Heinrich, M. A., Mangia, M. & Prakash, J., 1 May 2022, In: Trends in biotechnology. 40, 5, p. 532-534 3 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile12 Citations (Scopus)201 Downloads (Pure) -
Joint-on-chip platforms: entering a new era of in vitro models for arthritis
Paggi, C. A., Moreira Teixeira, L., le Gac, S. & Karperien, M., Apr 2022, In: Nature reviews rheumatology. 18, p. 217-231 15 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile54 Citations (Scopus)373 Downloads (Pure) -
One-Step Fabrication of Porous Membrane-Based Scaffolds by Air-Water Interfacial Phase Separation: Opportunities for Engineered Tissues
Allijn, I., du Preez, N., Tasior, M., Bansal, R. & Stamatialis, D., May 2022, In: Membranes. 12, 5, 453.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile8 Citations (Scopus)188 Downloads (Pure) -
Real-Time 1H and 31P NMR spectroscopy of the copolymerization of cyclic phosphoesters and trimethylene carbonate reveals transesterification from gradient to random copolymers
Rheinberger, T., Ankone, M., Grijpma, D. & Wurm, F. R., 5 Nov 2022, In: European polymer journal. 180, 6 p., 111607.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile5 Citations (Scopus)113 Downloads (Pure) -
Src kinase as a potential therapeutic target in non-alcoholic and alcoholic steatohepatitis
Kurniawan, D. W., Booijink, R. S., Jajoriya, A. K., Dhawan, G., Mishra, D., Oosterhuis, D., Argemi, J., Storm, G., Olinga, P., Bataller, R., Mohanty, S. K., Mishra, D. P., Prakash, J. & Bansal, R., 1 Mar 2022, In: Clinical and translational discovery. 2, 1, e18.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile4 Citations (Scopus)115 Downloads (Pure) -
Structure–property relations in semi-crystalline combinatorial poly(urethane-isocyanurate)-type hydrogels
Driest, P. J., Dijkstra, D. J., Stamatialis, D. & Grijpma, D. W., Sept 2022, In: Polymer international. 71, 9, p. 1055-1061 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus)151 Downloads (Pure) -
The Effect of Microbubble-Assisted Ultrasound on Molecular Permeability across Cell Barriers
Rousou, C., De Maar, J., Qiu, B., Van Der Wurff-Jacobs, K., Ruponen, M., Urtti, A., Oliveira, S., Moonen, C., Storm, G., Mastrobattista, E. & Deckers, R., Mar 2022, In: Pharmaceutics. 14, 3, 494.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile8 Citations (Scopus)79 Downloads (Pure) -
Tissue-adhesive hydrogel for multimodal drug release to immune cells in skin
Day, N. B., Dalhuisen, R., Loomis, N. E., Adzema, S. G., Prakash, J. & Shields IV, C. W., 15 Sept 2022, In: Acta biomaterialia. 150, p. 211-220 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile13 Citations (Scopus)249 Downloads (Pure) -
Ultrasound-directed enzyme-prodrug therapy (UDEPT) using self-immolative doxorubicin derivatives
Roemhild, K., Besse, H. C., Wang, B., Peña, Q., Sun, Q., Omata, D., Ozbakir, B., Bos, C., Scheeren, H. W., Storm, G., Metselaar, J. M., Yu, H., Knüchel-Clarke, R., Kiessling, F., Moonen, C. T. W., Deckers, R., Shi, Y. & Lammers, T., 6 Jun 2022, In: Theranostics. 12, 10, p. 4791-4801 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile13 Citations (Scopus)81 Downloads (Pure) -
2021
3D alveolar in vitro model based on epithelialized biomimetically curved culture membranes
Baptista, D., Teixeira, L. M., Birgani, Z. T., van Riet, S., Pasman, T., Poot, A., Stamatialis, D., Rottier, R. J., Hiemstra, P. S., Habibović, P., van Blitterswijk, C., Giselbrecht, S. & Truckenmüller, R., Jan 2021, In: Biomaterials. 266, 120436.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile36 Citations (Scopus)445 Downloads (Pure)