Research Output

2020

3D printed mold leachates in PDMS microfluidic devices

Ferraz, M., Nagashima, J. B., Venzac, B., le Gac, S. & Songsasen, N., 22 Jan 2020, In : Scientific reports. 10, 1, 994.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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1 Citation (Scopus)
25 Downloads (Pure)

A dog oviduct-on-a-chip model of serous tubal intraepithelial carcinoma

de Almeida Monteiro Melo Ferraz, M., Nagashima, J. B., Venzac, B., Le Gac, S. & Songsasen, N., 31 Jan 2020, In : Scientific reports. 10, 1, 1575.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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6 Downloads (Pure)

Electrochemical Detection of Tumor-Derived Extracellular Vesicles on Nanointerdigitated Electrodes

Mathew, D. G., Beekman, P., Lemay, S. G., Zuilhof, H., le Gac, S. & van der Wiel, W. G., 12 Feb 2020, In : Nano letters. 20, 2, p. 820-828

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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4 Citations (Scopus)
46 Downloads (Pure)

Ex-vivo culture of testis and epididymis tissues in a microfluidic devices

Venzac, B., le Gac, S., Burgers, T., Schlatt, S. & Sharma, S., 2020.

Research output: Contribution to conferenceOther

Metabolic Switching of Tumor Cells under Hypoxic Conditions in a Tumor-on-a-chip Model

Valentina, P-C., Kooijman, L. J., Venzac, B., Wouter, V. & le Gac, S., 4 Apr 2020, In : Micromachines. 11, 4, 382.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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6 Downloads (Pure)
2019

Aqueous-phase reforming: multiphase reaction engineering at the microscale

Ripken, R. M., 28 Jun 2019, Enschede: University of Twente. 202 p.

Research output: ThesisPhD Thesis - Research UT, graduation UT

Open Access
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177 Downloads (Pure)

Aqueous-Phase Reforming in a Microreactor: The Role of Surface Bubbles

Ripken, R. M., Wood, J. A., Gardeniers, J. G. E. & Le Gac, S., 1 Oct 2019, In : Chemical engineering and technology. 42, 10, p. 2179-2186 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)
2 Downloads (Pure)

Electrochemical quantification of EVs at physiological concentrations

Beekman, P., 25 Apr 2019.

Research output: Contribution to conferencePoster

Highly sensitive detection of tumor-derived extracellular vesicles using an enzymatic assay and redox cycling

Beekman, P., 26 Oct 2019, 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019. The Chemical and Biological Microsystems Society

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Immuno-capture of extracellular vesicles for individual multi-modal characterization using AFM, SEM and Raman spectroscopy

Beekman, P., Enciso-Martinez, A., Rho, H. S., Pujari, S. P., Lenferink, A., Zuilhof, H., Terstappen, L. W. M. M., Otto, C. & Le Gac, S., 7 Aug 2019, In : Lab on a chip. 19, 15, p. 2526-2536 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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6 Citations (Scopus)
13 Downloads (Pure)

Monitoring phase transition of aqueous biomass model substrates by high-pressure and high-temperature microfluidics

Ripken, R. M., Schlautmann, S., Sanders, R. G. P., Gardeniers, J. G. E. & le Gac, S., 15 Feb 2019, In : Electrophoresis. 40, 4, p. 563-570 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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1 Citation (Scopus)
34 Downloads (Pure)

PDMS curing inhibition by 3D-printed templates. Why? And how to avoid it

Venzac, B., le Gac, S., Yang, S., Lenferink, A. T. M. & Otto, C., 2019.

Research output: Contribution to conferencePoster

PDMS curing inhibition by 3D-printed templates. Why? And how to avoid it

Venzac, B., le Gac, S., Otto, C. & Lenferink, A. T. M., 2019.

Research output: Contribution to conferencePoster

Shear-free and robust trapping of oocytes in an oviduct-on-chip.

Venzac, B., le Gac, S., Gadella, B. & Henning, H. H. W., 2019.

Research output: Contribution to conferencePoster

Sonoprinting liposomes on tumor spheroids by microbubbles and ultrasound

Roovers, S., Deprez, J., Priwitaningrum, D., Lajoinie, G., Rivron, N., Declercq, H., De Wever, O., Stride, E., Le Gac, S., Versluis, M., Prakash, J., De Smedt, S. C. & Lentacker, I., 28 Dec 2019, In : Journal of controlled release. 316, p. 79-92 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

1 Downloads (Pure)
2018

A cartilage-on-a-chip platform recapitulating joint motion

Paggi, C. A., Venzac, B., Leijten, J. & le Gac, S., 30 Oct 2018.

Research output: Contribution to conferencePoster

A microfluidic droplet serial dilutor with enhanced mixing

Rho, H. S., Yang, Y., Terstappen, L. W. M. M., Habibovic, P. & le Gac, S., 11 Nov 2018.

Research output: Contribution to conferencePoster

A microfluidic droplet serial dilutor with enhanced mixing

Rho, H. S., Yang, Y., Terstappen, L. W. M. M., Habibović, P. & le Gac, S., 11 Nov 2018, MicroTas 2018: 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences. Tseng, F-G. & Lee, G-B. (eds.). The Chemical and Biological Microsystems Society, p. 1114-1115 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

Open Access
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2 Downloads (Pure)

An oviduct-on-a-chip provides an enhanced in vitro environment for zygote genome reprogramming

Ferraz, M. A. M. M., Rho, H. S., Hemerich, D., Henning, H. H. W., van Tol, H. T. A., Hoelker, M., Besenfelder, U., Mokry, M., Vos, P. L. A. M., Stout, T. A. E., Le Gac, S. & Gadella, B. M., 22 Nov 2018, In : Nature communications. 9, 4934.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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19 Citations (Scopus)
29 Downloads (Pure)

Controlled bubble nucleation in gas-liquid-solid catalytic microsystems for enhanced mass transport

Ripken, R. M., Wood, J. A., Schlautmann, S., Gunther, A., Gardeniers, H. & le Gac, S., 11 Nov 2018, MicroTas 2018: 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences. Tseng, F-G. & Lee, G-B. (eds.). The Chemical and Biological Microsystems Society, p. 409-410 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

Open Access
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3 Downloads (Pure)

ELASTO-TWEEZERS: a novel platform for high-precision cell elasticity measurements

Knust, S., Sischka, A., Milting, H., Venzac, B., le Gac, S., Vrouwe, E., Viefhues, M., Anselmetti, D. & Gall, K., 11 Nov 2018.

Research output: Contribution to conferencePoster

Elasto-Tweezers : high-precision measurement of the elasticity of patterned cells on-chip

Knust, S., Sischka, A., Milting, H., Venzac, B., le Gac, S., Vrouwe, E., Viefhues, M., Anselmetti, D. & Gall, K., 11 Dec 2018.

Research output: Contribution to conferenceOther

Electroporation in Microfluidic devices

le Gac, S. & Van Uitert, I., 2018, Handbook of electroporation. Miklavčič, D. (ed.). Springer

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

3 Downloads (Pure)

Enhancing nanomedicine penetration in tumor-on-a-chip models using ultrasound-mediated microbubble activation

Bokkers, A. M., Blondé, J-B., Lentacker, I., Versluis, M., Lajoinie, G. & Le Gac, S., 2018, MicroTAS 2018: 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences. Tseng, F-G. & Lee, G-B. (eds.). The Chemical and Biological Microsystems Society, Vol. 3. p. 1620-1621 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Open Access
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5 Downloads (Pure)

Immunocapturing of extracellular vesicles on stainless steel for multi-modal individual characterization with correlative light, electron and probe microscopy

Beekman, P., Enciso Martinez, A., Terstappen, L., Otto, C. & le Gac, S., 11 Nov 2018, MicroTas 2018: 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences. Tseng, F-G. & Lee, G-B. (eds.). The Chemical and Biological Microsystems Society, p. 2402-2403 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

Open Access
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2 Downloads (Pure)
Open Access
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1 Citation (Scopus)
36 Downloads (Pure)

In-vitro spermatogenesis study using testis-on-chip models

Venzac, B., Sharma, S., Rho, H. S., Ghazarian, N., Schlatt, S. & le Gac, S., 30 Nov 2018.

Research output: Contribution to conferencePoster

MICROFLUIDIC DEVICE FOR MECHANICALLY STIMULATING A MATERIAL

le Gac, S., J., L., Paggi, C. A. & Venzac, B., 2018, (Submitted) Patent No. EP18202998, 26 Oct 2018

Research output: Patent

Mimicking articular motion in a cartilage-on-a-chip model

Paggi, C. A., Venzac, B., Leijten, J. & le Gac, S., 11 Nov 2018.

Research output: Contribution to conferencePoster

Parallel probing of drug uptake of single cancer cells on a microfluidic device

Yang, Y. S., le Gac, S., Terstappen, L. & Rho, H. S., 1 Feb 2018, In : Electrophoresis. 39, 3, p. 548-556 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)
2 Downloads (Pure)

Potential Health and Environmental Risks of Three-Dimensional Engineered Polymers

de Almeida Monteiro Melo Ferraz, M., Henning, H. H. W., Ferreira da Costa, P., Malda, J., le Gac, S., Bray, F., van Duursen, M. B. M., Brouwers, J., van de Lest, C. H. A., Bertijn, I., Kraneburg, L., Vos, P. L. A. M., Stout, T. A. E. & Gadella, B. M., 5 Jan 2018, In : Environmental science & technology letters. 5, 2, p. 80-85 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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9 Citations (Scopus)
26 Downloads (Pure)

Single-Cell Microgels: Technology, Challenges, and Applications

Kamperman, T., Karperien, M., Le Gac, S. & Leijten, J., Aug 2018, In : Trends in biotechnology. 36, 8, p. 850-865 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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15 Citations (Scopus)
114 Downloads (Pure)

Studying Nanoparticle Penetration in 3D Multicellular Tumour Models On-Chip

Blondé, J-B., Priwitaningrum, D., Prakash, J. & le Gac, S., Oct 2018.

Research output: Contribution to conferencePoster

2 Downloads (Pure)

Testis-on-chip models to study in-vitro human spermatogenesis

Venzac, B., Sharma, S., Rho, H. S., Ghazarian, N., Schlatt, S. & le Gac, S., 10 Dec 2018.

Research output: Contribution to conferencePoster

Tumour-on-a-chip platform to evaluate nanoparticles penetration in 3D co-culture tumour spheroids

Blondé, J-B., Priwitaningrum, D., Prakash, J. & le Gac, S., 13 Nov 2018, MicroTAS 2018: 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences. Tseng, F-G. & Lee, G-B. (eds.). The Chemical and Biological Microsystems Society, p. 1959-1960 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Open Access
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5 Downloads (Pure)
2017

Characterization of Extracellular Vesicles using Raman Spectroscopy

Lee, W., Nanou, A., Terstappen, L. W. M. M., Rho, H. S., le Gac, S. & Offerhaus, H. L., 17 Jan 2017.

Research output: Contribution to conferencePoster

44 Downloads (Pure)

Influence of the Water Phase State on the Thermodynamics of Aqueous Phase Reforming for Hydrogen Production

Ripken, R. M., Meuldijk, J., Gardeniers, J. G. E. & le Gac, S., 2017, In : ChemSusChem. 10, 24, p. 4909-4913

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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6 Citations (Scopus)
52 Downloads (Pure)

Microfluidic Platform for Parallel Single Cell Analysis for Diagnostic Applications

le Gac, S., 2017, Microchip Diagnostics. Taly, V., Descroix, S. & Viovy, J-L. (eds.). Springer, p. 187-209 (Methods in Molecular Biology; vol. 1547).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Microfluidic technology: new opportunities to develop physiologically relevant in vitro models integrated microfluidic platform for the in vitro pre-implantation culture of individual mammalian embryos and their in situ characterization

le Gac, S., 11 Sep 2017, 47th European Solid-State Device Research Conference (ESSDERC 2017). Piscataway, NJ: IEEE, p. 260-263

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Mimicking the bovine oviduct in a microfluidic device for advanced embryo in vitro culture systems

Ferraz, M., Rho, H. S., Delahaye, J., Pinheiro, N., Henning, H., Stout, T., Gadella, B. & le Gac, S., 22 Oct 2017. 2 p.

Research output: Contribution to conferencePoster

Open Access
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5 Downloads (Pure)

Mimicking the bovine oviduct in a microfluidic platform for embryo in vitro production and in vitro culture

le Gac, S., Venzac, B., Rho, H. S., Ferraz, M., Henning, H., Pinheiro, N., Gadella, B. & Stout, T., 13 Nov 2017.

Research output: Contribution to conferencePoster

Monitoring the respiratory activity of multicellular tumor spheroids in an integrated microfluidic device

Abbas, Y., van Rossem, F., Bomer, J. & le Gac, S., 22 Oct 2017. 2 p.

Research output: Contribution to conferencePoster

Monitoring the respiratory activity of multicellular tumor spheroids in an integrated microfluidic device

Abbas, Y., van Rossem, F., Bomer, J. & le Gac, S., 22 Oct 2017, 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences. Lee, A. & DeVoe, D. (eds.). The Chemical and Biological Microsystems Society, p. 455-456 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

Open Access
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