Research Output 2015 2019

2019
76 Downloads (Pure)

Aqueous-phase reforming: multiphase reaction engineering at the microscale

Ripken, R. M., 28 Jun 2019, Enschede: University of Twente. 202 p.

Research output: ThesisPhD Thesis - Research UT, graduation UTAcademic

Open Access
File
Reforming reactions
Hydrogen
Gases
Thermodynamics
Hydrogen production
11 Downloads (Pure)

Electrochemical Detection of Tumor-Derived Extracellular Vesicles on Nanointerdigitated Electrodes

Mathew, D. G., Beekman, P., Lemay, S. G., Zuilhof, H., le Gac, S. & van der Wiel, W. G., 19 Sep 2019, (Accepted/In press) In : Nano letters.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Tumors
tumors
Blood
blood
Electrodes
1 Citation (Scopus)

Immuno-capture of extracellular vesicles for individual multi-modal characterization using AFM, SEM and Raman spectroscopy

Beekman, P., Enciso-Martinez, A., Rho, H. S., Pujari, S. P., Lenferink, A., Zuilhof, H., Terstappen, L. W. M. M., Otto, C. & Le Gac, S., 7 Aug 2019, In : Lab on a chip. 19, 15, p. 2526-2536 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Raman Spectrum Analysis
Raman spectroscopy
Tumors
Stainless Steel
Scanning electron microscopy
1 Citation (Scopus)
21 Downloads (Pure)

Monitoring phase transition of aqueous biomass model substrates by high-pressure and high-temperature microfluidics

Ripken, R. M., Schlautmann, S., Sanders, R. G. P., Gardeniers, J. G. E. & le Gac, S., 15 Feb 2019, In : Electrophoresis. 40, 4, p. 563-570 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Microfluidics
Phase Transition
Reforming reactions
Biomass
Xylitol

Sonoprinting liposomes on tumor spheroids by microbubbles and ultrasound

Roovers, S., Deprez, J., Priwitaningrum, D., Lajoinie, G., Rivron, N., Declercq, H., De Wever, O., Stride, E., Le Gac, S., Versluis, M., Prakash, J., De Smedt, S. C. & Lentacker, I., 29 Oct 2019, In : Journal of controlled release. 316, p. 79-92 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Microbubbles
Liposomes
Doxorubicin
Neoplasms
Pharmaceutical Preparations
2018

A cartilage-on-a-chip platform recapitulating joint motion

Paggi, C. A., Venzac, B., Leijten, J. & le Gac, S., 30 Oct 2018.

Research output: Contribution to conferencePosterAcademic

A microfluidic droplet serial dilutor with enhanced mixing

Rho, H. S., Yang, Y., Terstappen, L. W. M. M., Habibovic, P. & le Gac, S., 11 Nov 2018.

Research output: Contribution to conferencePosterAcademic

A microfluidic droplet serial dilutor with enhanced mixing

Rho, H. S., Yoonsun, Y., Terstappen, L. W. M. M., Habibović, P. & le Gac, S., 11 Nov 2018.

Research output: Contribution to conferencePaperAcademic

6 Citations (Scopus)
17 Downloads (Pure)

An oviduct-on-a-chip provides an enhanced in vitro environment for zygote genome reprogramming

Ferraz, M. A. M. M., Rho, H. S., Hemerich, D., Henning, H. H. W., van Tol, H. T. A., Hoelker, M., Besenfelder, U., Mokry, M., Vos, P. L. A. M., Stout, T. A. E., Le Gac, S. & Gadella, B. M., 22 Nov 2018, In : Nature communications. 9, 4934.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

Controlled bubble nucleation in gas-liquid-solid catalytic microsystems for enhanced mass transport

Ripken, R. M., Wood, J. A., Schlautmann, S., Gunther, A., Gardeniers, H. & le Gac, S., 11 Nov 2018.

Research output: Contribution to conferencePaperAcademic

ELASTO-TWEEZERS: a novel platform for high-precision cell elasticity measurements

Knust, S., Sischka, A., Milting, H., Venzac, B., le Gac, S., Vrouwe, E., Viefhues, M., Anselmetti, D. & Gall, K., 11 Nov 2018.

Research output: Contribution to conferencePosterAcademic

Elasto-Tweezers : high-precision measurement of the elasticity of patterned cells on-chip

Knust, S., Sischka, A., Milting, H., Venzac, B., le Gac, S., Vrouwe, E., Viefhues, M., Anselmetti, D. & Gall, K., 11 Dec 2018.

Research output: Contribution to conferenceOtherAcademic

1 Downloads (Pure)

Electroporation in Microfluidic devices

le Gac, S. & Van Uitert, I., 2018, Handbook of electroporation. Miklavčič, D. (ed.). Springer

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Microfluidics
Cells
Cell membranes
Cell engineering
Joule heating
1 Citation (Scopus)
4 Downloads (Pure)
Open Access
File
Lipid bilayers
Microfluidics
Confocal microscopy
Lipid Bilayers
Ion Channels

In-vitro spermatogenesis study using testis-on-chip models

Venzac, B., Sharma, S., Rho, H. S., Ghazarian, N., Schlatt, S. & le Gac, S., 30 Nov 2018.

Research output: Contribution to conferencePosterAcademic

MICROFLUIDIC DEVICE FOR MECHANICALLY STIMULATING A MATERIAL

le Gac, S., J., L., Paggi, C. A. & Venzac, B., 2018, (Submitted) Patent No. EP18202998, 26 Oct 2018

Research output: PatentProfessional

Mimicking articular motion in a cartilage-on-a-chip model

Paggi, C. A., Venzac, B., Leijten, J. & le Gac, S., 11 Nov 2018.

Research output: Contribution to conferencePosterAcademic

2 Citations (Scopus)
2 Downloads (Pure)

Parallel probing of drug uptake of single cancer cells on a microfluidic device

Yang, Y. S., le Gac, S., Terstappen, L. & Rho, H. S., 1 Feb 2018, In : Electrophoresis. 39, 3, p. 548-556 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Lab-On-A-Chip Devices
Microfluidics
Cells
Pharmaceutical Preparations
Neoplasms
8 Citations (Scopus)
12 Downloads (Pure)

Potential Health and Environmental Risks of Three-Dimensional Engineered Polymers

de Almeida Monteiro Melo Ferraz, M., Henning, H. H. W., Ferreira da Costa, P., Malda, J., le Gac, S., Bray, F., van Duursen, M. B. M., Brouwers, J., van de Lest, C. H. A., Bertijn, I., Kraneburg, L., Vos, P. L. A. M., Stout, T. A. E. & Gadella, B. M., 5 Jan 2018, In : Environmental science & technology letters. 5, 2, p. 80-85 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Environmental Health
environmental risk
health risk
Polymers
polymer
7 Citations (Scopus)
43 Downloads (Pure)

Single-Cell Microgels: Technology, Challenges, and Applications

Kamperman, T., Karperien, M., Le Gac, S. & Leijten, J., Aug 2018, In : Trends in biotechnology. 36, 8, p. 850-865 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Technology
Pharmacokinetics
Encapsulation
Screening
Mass transfer
1 Downloads (Pure)

Studying Nanoparticle Penetration in 3D Multicellular Tumour Models On-Chip

Blondé, J-B., Priwitaningrum, D., Prakash, J. & le Gac, S., Oct 2018.

Research output: Contribution to conferencePosterAcademic

Nanoparticles
Neoplasms
Fibroblasts
Cellular Spheroids
Nanomedicine

Testis-on-chip models to study in-vitro human spermatogenesis

Venzac, B., Sharma, S., Rho, H. S., Ghazarian, N., Schlatt, S. & le Gac, S., 10 Dec 2018.

Research output: Contribution to conferencePosterAcademic

Tumour-on-a-chip platform to evaluate nanoparticles penetration in 3D co-culture tumour spheroids

Blondé, J-B., Priwitaningrum, D., Prakash, J. & le Gac, S., 13 Nov 2018, MicroTAS 2018: 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences. The Chemical and Biological Microsystems Society, 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Coculture Techniques
Nanoparticles
Neoplasms
Fibroblasts
Cellular Spheroids
2017

Characterization of Extracellular Vesicles using Raman Spectroscopy

Lee, W., Nanou, A., Terstappen, L. W. M. M., Rho, H. S., le Gac, S. & Offerhaus, H. L., 17 Jan 2017.

Research output: Contribution to conferencePosterOther research output

microchannels
chutes
Raman spectroscopy
borosilicate glass
cultured cells
39 Downloads (Pure)

Influence of bubble growth at the catalytic surface on the heat and mass transfer in gas-liquid-solid microsystems

Ripken, R. M., Wood, J. A., Gardeniers, J. G. E. & le Gac, S., 2017.

Research output: Contribution to conferenceAbstractOther research output

Open Access
File
5 Citations (Scopus)
36 Downloads (Pure)

Influence of the Water Phase State on the Thermodynamics of Aqueous Phase Reforming for Hydrogen Production

Ripken, R. M., Meuldijk, J., Gardeniers, J. G. E. & le Gac, S., 2017, In : ChemSusChem. 10, 24, p. 4909-4913

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Reforming reactions
Hydrogen production
thermodynamics
Thermodynamics
hydrogen

Microfluidic Platform for Parallel Single Cell Analysis for Diagnostic Applications

le Gac, S., 2017, Microchip Diagnostics. Taly, V., Descroix, S. & Viovy, J-L. (eds.). Springer, p. 187-209 (Methods in Molecular Biology; vol. 1547).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Microfluidics
Cells
Biomarkers
Cell membranes
Medicine

Microfluidic technology: new opportunities to develop physiologically relevant in vitro models integrated microfluidic platform for the in vitro pre-implantation culture of individual mammalian embryos and their in situ characterization

le Gac, S., 11 Sep 2017, 47th European Solid-State Device Research Conference (ESSDERC 2017). Piscataway, NJ: IEEE, p. 260-263

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Mimicking the bovine oviduct in a microfluidic device for advanced embryo in vitro culture systems

Ferraz, M., Rho, H. S., delahaye, J., Pinheiro, N., Henning, H., Stout, T., Gadella, B. & le Gac, S., 22 Oct 2017. 2 p.

Research output: Contribution to conferencePosterOther research output

Mimicking the bovine oviduct in a microfluidic platform for embryo in vitro production and in vitro culture

le Gac, S., Venzac, B., Rho, H. S., Ferraz, M., Henning, H., Pinheiro, N., Gadella, B. & Stout, T., 13 Nov 2017.

Research output: Contribution to conferencePosterOther research output

Monitoring the respiratory activity of multicellular tumor spheroids in an integrated microfluidic device

le Gac, S., Abbas, Y., van Rossem, F. & Bomer, J. G., 22 Oct 2017.

Research output: Contribution to conferencePaperAcademic

Monitoring the respiratory activity of multicellular tumor spheroids in an integrated microfluidic device

Abbas, Y., van Rossem, F., Bomer, J. G. & le Gac, S., 22 Oct 2017. 2 p.

Research output: Contribution to conferencePosterOther research output

5 Citations (Scopus)
18 Downloads (Pure)

Multiwell capillarity-based microfluidic device for the study of 3D tumour tissue-2D endothelium interactions and drug screening in co-culture model

Virumbrales-Munoz, M., Ayuso, J. M., Olave, M., Monge, R., de Miguel, D., Martinez-Lostao, L., le Gac, S., Doblare, M., Ochoa, I. & Fernandez, L. J., 20 Sep 2017, In : Scientific reports. 7, 15 p., 11998.

Research output: Contribution to journalArticleProfessional

Open Access
File
Lab-On-A-Chip Devices
Capillary Action
Preclinical Drug Evaluations
Coculture Techniques
Endothelium
60 Downloads (Pure)

Photocatalytic reforming of biomass for hydrogen production

Ripken, R. M., de Boer, V. J. H. W., Gardeniers, J. G. E. & le Gac, S., 2017.

Research output: Contribution to conferencePosterOther research output

Open Access
File
Reforming reactions
Hydrogen production
Biomass
Xylitol
Ethylene Glycol

Real-time monitoring of complex multiphase behavior in a high pressure and high temperature microfluidic chip

Ripken, R. M., Gardeniers, H. & le Gac, S., 22 Oct 2017. 2 p.

Research output: Contribution to conferencePosterOther research output

28 Downloads (Pure)

Real-Time Monitoring of Complex Multiphase Behavior in a High Pressure High Temperature Microfluidic Chip

Ripken, R. M., Gardeniers, J. G. E. & le Gac, S., 2017.

Research output: Contribution to conferenceAbstractOther research output

Open Access
File
5 Citations (Scopus)
2 Downloads (Pure)

Sensing oxygen at the millisecond time-scale using an ultra-microelectrode array (UMEA)

van Rossem, F., Bomer, J. G., de Boer, H. L., Abbas, Y., de Weerd, E., van den Berg, A. & Le Gac, S., 1 Jan 2017, In : Sensors and actuators. B: Chemical. 238, p. 1008-1016 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Microelectrodes
Oxygen
Sensor arrays
sensors
oxygen
2016

Controlled bubble nucleation in gas-liquid-solid catalytic microsystems for enhanced mass transport

Ripken, R. M., Wood, J. A., Schlautmann, S., Guenther, A., Gardeniers, J. G. E. & le Gac, S., Mar 2016.

Research output: Contribution to conferencePosterAcademic

8 Citations (Scopus)

Microfluidics for mammalian embryo culture and selection: where do we stand now?

le Gac, S. & Nordhoff, V., 4 Oct 2016, In : Molecular Human Reproduction. 23, 4, p. 213-226 14 p.

Research output: Contribution to journalLiterature reviewAcademicpeer-review

Mammalian Embryo
Microfluidics
Embryonic Structures
Technology
Cryopreservation

Thermodynamic study of aqueous phase reforming for hydrogen production

Ripken, R. M., Gardeniers, J. G. E. & le Gac, S., 2016.

Research output: Contribution to conferencePosterOther research output

2015

Microfluidic devices for the interrogation of single circulating tumor cells

Yang, Y. S., Rho, H. S., Swennenhuis, J. F., Stevens, M., Tibbe, A. G. J., le Gac, S., Gardeniers, H. & Terstappen, L. W. M. M., 20 Apr 2015.

Research output: Contribution to conferencePosterOther research output

Lab-On-A-Chip Devices
Circulating Neoplastic Cells
DNA
Neoplasms
Pharmaceutical Preparations