Research Output 2015 2020

2019
4 Citations (Scopus)
285 Downloads (Pure)

Advanced in vitro models of vascular biology: Human induced pluripotent stem cells and organ-on-chip technology

Cochrane, A., Albers, H. J., Passier, R., Mummery, C. L., van den Berg, A., Orlova, V. V. & van der Meer, A., 1 Feb 2019, In : Advanced drug delivery reviews. 140, p. 68-77 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Induced Pluripotent Stem Cells
Blood Vessels
Technology
Microfluidics
Pharmaceutical Preparations
4 Downloads (Pure)

Apolipoprotein E associated with reconstituted high-density lipoprotein-like particles is protected from aggregation

Hubin, E., Verghese, P. B., van Nuland, N. & Broersen, K., 1 Jun 2019, In : FEBS letters. 593, 11, p. 1144-1153 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Apolipoproteins E
HDL Lipoproteins
Agglomeration
Apolipoprotein E4
Lipids

Development of double porous poly (ε - caprolactone)/chitosan polymer as tissue engineering scaffold

Das, P., Remigy, J. C., Lahitte, J. F., van der Meer, A. D., Garmy-Susini, B., Coetsier, C., Desclaux, S. & Bacchin, P., 14 Oct 2019, In : Materials Science and Engineering C. 107, 110257.

Research output: Contribution to journalArticleAcademicpeer-review

Tissue Scaffolds
tissue engineering
Chitosan
Scaffolds (biology)
Tissue engineering
1 Citation (Scopus)
14 Downloads (Pure)

Flow focusing through gels as a tool to generate 3D concentration profiles in hydrogel-filled microfluidic chips

Loessberg-Zahl, J., Van der Meer, A. D., Van Den Berg, A. & Eijkel, J. C. T., 21 Jan 2019, In : Lab on a chip. 19, 2, p. 206-213 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Microfluidics
Hydrogel
Hydrogels
Gels
Technology

Investigation into the molecular complexity of Alzheimer's disease: an amyloid-ß centered approach

Cioffi, F., 20 Sep 2019, Enschede: University of Twente. 320 p.

Research output: ThesisPhD Thesis - Research UT, graduation UTAcademic

Amyloid
Alzheimer Disease
Interferon-gamma
Oxidative Stress
Research

Native cardiac environment and its impact on engineering cardiac tissue

Schwach, V. & Passier, R., 1 Sep 2019, In : Biomaterials Science. 7, 9, p. 3566-3580 15 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Stem cells
Tissue
Biocompatible Materials
Tissue engineering
Biomaterials
4 Citations (Scopus)
16 Downloads (Pure)

Non-invasive sensing of transepithelial barrier function and tissue differentiation in organs-on-chips using impedance spectroscopy

van der Helm, M. W., Henry, O. Y. F., Bein, A., Hamkins-Indik, T., Cronce, M. J., Leineweber, W. D., Odijk, M., van der Meer, A. D., Eijkel, J. C. T., Ingber, D. E., van den Berg, A. & Segerink, L. I., 29 Jan 2019, In : Lab on a chip. 19, 3, p. 452-463 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Dielectric Spectroscopy
Electric Impedance
Acoustic impedance
Cells
Spectroscopy

Organs-on-Chips: a new paradigm for safety assessment of drug-induced thrombosis

Ng, P., Belgur, C., Barthakur, S., van der Meer, A. D., Hamilton, G. A. & Barrile, R., 1 Oct 2019, In : Current Opinion in Toxicology. 17, p. 1-8 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Thrombosis
Safety
Animal Models
Pharmaceutical Preparations
Mechanical Stress
9 Citations (Scopus)
8 Downloads (Pure)

Personalised organs-on-chips: functional testing for precision medicine

Van Den Berg, A., Mummery, C. L., Passier, R. & Van der Meer, A. D., 21 Jan 2019, In : Lab on a chip. 19, 2, p. 198-205 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Precision Medicine
Medicine
Physiology
Testing
Cell culture
1 Downloads (Pure)

Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes

van Meer, B. J., Krotenberg, A., Sala, L., Davis, R. P., Eschenhagen, T., Denning, C., Tertoolen, L. G. J. & Mummery, C. L., 20 Sep 2019, In : Nature communications. 10, 1, 9 p., 4325.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Induced Pluripotent Stem Cells
Excitation Contraction Coupling
Cardiac Myocytes
Action Potentials
contraction

Standardized, modular microfluidic building blocks for automated cell culturing systems

Vollertsen, A., Bossink, E., de Boer, D., Spalink, J., Passier, R., van den Berg, A., Segerink, L., van der Meer, A. & Odijk, M., 28 Oct 2019, 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences. Diettrich, P., Delamarche, E. & Hierlemann, A. (eds.). 23 ed. Basel, Switzerland: Chemical and Biological Micro Systems Society, p. 86-87 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Microfluidics
Fluidics
Encapsulation
Assays
Screening
2018
9 Citations (Scopus)
26 Downloads (Pure)

Advanced Good Cell Culture Practice for Human Primary, Stem Cell-Derived and Organoid Models as well as Microphysiological Systems

Pamies, D., Bal-Price, A., Chesne, C., Coecke, S., Dinnyes, A., Eskes, C., Grillari, R., Gstraunthaler, G., Hartung, T., Jennings, P., Leist, M., Martin, U., Passier, R., Schwamborn, J. C., Stacey, G. N., Ellinger-Ziegelbauer, H. & Daneshian, M., 9 Jul 2018, In : Alternatives to Animal Experimentation. 35, 3, p. 353-378 26 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

A novel method to transfer porous PDMS membranes for high throughput Organ-on-Chip and Lab-on-Chip assembly

Quiros-Solano, W. F., Gaio, N., Silvestri, C., Arik, Y. B., Stassen, O. M. J. A., Van Der Meer, A. D., Bouten, C. V. C., Van Den Berg, A., Dekker, R. & Sarro, P. M., 24 Apr 2018, 2018 IEEE Micro Electro Mechanical Systems, MEMS 2018. IEEE, Vol. 2018-January. p. 318-321 4 p. (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS); vol. 2018-January).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Open Access
File
Polydimethylsiloxane
organs
assembly
chips
Throughput
7 Citations (Scopus)
47 Downloads (Pure)

Barriers-on-chips: Measurement of barrier function of tissues in organs-on-chips

Arık, Y. B., van der Helm, M. W., Odijk, M., Segerink, L. I., Passier, R., van den Berg, A. & van der Meer, A. D., 1 Jul 2018, In : Biomicrofluidics. 12, 4, 042218.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
organs
chips
Tissue
Cells
Equipment Design
7 Citations (Scopus)
15 Downloads (Pure)

Cardiac differentiation of pluripotent stem cells and implications for modeling the heart in health and disease

Devalla, H. D. & Passier, R., 4 Apr 2018, In : Science Translational Medicine. 10, 435, eaah5457.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Pluripotent Stem Cells
Regenerative Medicine
Tissue Engineering
Cardiac Myocytes
Heart Diseases

Differentiation and validation of human iPSC-derived atrial cardiomyocytes

Sutton, K., El Haou, S., Williams, S., Devalla, H., Stoelzle-Feix, S., Juhasz, K., Doerr, L., Beckler, M., Haarmann, C., George, M., Passier, R., Fertig, N. & Rogers, M., 13 Sep 2018, In : Journal of Pharmacological and Toxicological Methods. 93, p. 168-168 176.

Research output: Contribution to journalMeeting AbstractAcademic

1 Citation (Scopus)
62 Downloads (Pure)

Evolution of the Proximal Sealing Rings of the Anaconda Stent-Graft After Endovascular Aneurysm Repair

Koenrades, M. A., Klein, A., Leferink, A. M., Slump, C. H. & Geelkerken, R. H., 1 Aug 2018, In : Journal of Endovascular Therapy. 25, 4, p. 480-491 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Boidae
Stents
Aneurysm
Transplants
Endoleak

Flow Through Gels as a Tool to Generate 3D Concentration Profiles in Hydrogel-Filled Devices

Loessberg-Zahl, J., van der Meer, A. D., van den Berg, A. & Eijkel, J. C. T., 11 Nov 2018, MicroTAS 2018: The 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences. Lee, G-B. & F-G. T. (eds.). The Chemical and Biological Microsystems Society, p. 2239-2241 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

solute
gel
collagen
laminar flow
dye

Human induced pluripotent stem cell-derived endothelial cells in thrombosis-on-a-chip devices

Albers, H. J., da Silva Simão, J. P., Middelkamp, H. H. T., Mummery, C. L., Passier, R., van den Berg, A., Orlova, V. V. & van der Meer, A. D., 11 Nov 2018. 1 p.

Research output: Contribution to conferencePosterAcademic

12 Citations (Scopus)
51 Downloads (Pure)

Interpretation of field potentials measured on a multi electrode array in pharmacological toxicity screening on primary and human pluripotent stem cell-derived cardiomyocytes

Tertoolen, L. G. J., Braam, S. R., van Meer, B. J., Passier, R. & Mummery, C. L., 18 Mar 2018, In : Biochemical and biophysical research communications. 497, 4, p. 1135-1141 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Pluripotent Stem Cells
Stem cells
Cardiac Myocytes
Toxicity
Screening
10 Citations (Scopus)
38 Downloads (Pure)

Large-scale fabrication of free-standing and sub-μm PDMS through-hole membranes

Le-The, H., Tibbe, M., Loessberg-Zahl, J., Palma Do Carmo, M., Van Der Helm, M., Bomer, J., Van Den Berg, A., Leferink, A., Segerink, L. & Eijkel, J., 28 Apr 2018, In : Nanoscale. 10, 16, p. 7711-7718 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Polydimethylsiloxane
Membranes
Fabrication
Photoresists
Sulfur Hexafluoride

Membranes for Organs-on-Chips

Tibbe, M. P., van der Meer, A. D., van den Berg, A., Stamatialis, D. & Segerink, L., 2018, Biomedical Membranes and (Bio)Artificial Organs. Stamatialis, D. (ed.). World Scientific, p. 295-321 (World Scientific Series in Membrane Science and Technology: Biological and Biomimetic Applications, Energy and the Environment: ; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

1 Citation (Scopus)
42 Downloads (Pure)

Microfabricated tuneable and transferable porous PDMS membranes for Organs-on-Chips

Quirós-Solano, W. F., Gaio, N., Stassen, O. M. J. A., Arik, Y. B., Silvestri, C., Van Engeland, N. C. A., van der Meer, A., Passier, R., Sahlgren, C. M., Bouten, C. V. C., van den Berg, A., Dekker, R. & Sarro, P. M., 10 Sep 2018, In : Scientific reports. 8, 1, 13524.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Membranes
Cells
Fabrication
Endothelial cells
Physiology
17 Citations (Scopus)
24 Downloads (Pure)

Musclemotion: A versatile open software tool to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo

Sala, L., Van Meer, B. J., Tertoolen, L. G. J., Bakkers, J., Bellin, M., Davis, R. P., Denning, C., Dieben, M. A. E., Eschenhagen, T., Giacomelli, E., Grandela, C., Hansen, A., Holman, E. R., Jongbloed, M. R. M., Kamel, S. M., Koopman, C. D., Lachaud, Q., Mannhardt, I., Mol, M. P. H., Mosqueira, D. & 7 othersOrlova, V. V., Passier, R., Catarino Ribeiro, M., Saleem, U., Smith, G. L., Burton, F. L. & Mummery, C. L., 2 Feb 2018, In : Circulation research. 122, 3, p. e5-e16

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Muscle Contraction
Cardiac Myocytes
Myocardium
Software
Pluripotent Stem Cells
14 Citations (Scopus)

Organ-on-Chip Recapitulates Thrombosis Induced by an anti-CD154 Monoclonal Antibody: Translational Potential of Advanced Microengineered Systems

Barrile, R., van der Meer, A. D., Park, H., Fraser, J. P., Simic, D., Teng, F., Conegliano, D., Nguyen, J., Jain, A., Zhou, M., Karalis, K., Ingber, D. E., Hamilton, G. A. & Otieno, M. A., Dec 2018, In : Clinical pharmacology & therapeutics. 104, 6, p. 1240-1248 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

CD40 Ligand
Thrombosis
Monoclonal Antibodies
Thrombin
Platelet Activation
38 Citations (Scopus)
11 Downloads (Pure)

Primary Human Lung Alveolus-on-a-chip Model of Intravascular Thrombosis for Assessment of Therapeutics

Jain, A., Barrile, R., van der Meer, A. D., Mammoto, A., Mammoto, T., De Ceunynck, K., Aisiku, O., Otieno, M. A., Louden, C. S., Hamilton, G. A., Flaumenhaft, R. & Ingber, D. E., 1 Feb 2018, In : Clinical pharmacology & therapeutics. 103, 2, p. 332-340 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Thrombosis
Lung
Microfluidics
Endothelium
Therapeutics
51 Downloads (Pure)

Standardized, Modular Parallelization Platform for Microfluidic Large-Scale Integration Cell Culturing Chips

Vollertsen, A. R., Dekker, S., Wesselink, B. A. M., Haverkate, R., Bomer, J. G., Rho, H. S., Boom, R. J., Skolimowski, M., Blom, M., van der Meer, A., Passier, R., van den Berg, A. & Odijk, M., 11 Nov 2018, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences: MicroTAS. p. 2199-2201 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Open Access
File
Microfluidics
Lab-On-A-Chip Devices
Human Umbilical Vein Endothelial Cells
Drug Industry
Cell Culture Techniques

The Next Chapter for Stem Cell Reports

Mummery, C., 11 Dec 2018, In : Stem cell reports. 11, 6, p. 1303-1304 2 p.

Research output: Contribution to journalEditorialAcademicpeer-review

2017
8 Citations (Scopus)
32 Downloads (Pure)

A COUP-TFII Human Embryonic Stem Cell Reporter Line to Identify and Select Atrial Cardiomyocytes

Schwach, V., Verkerk, A. O., Mol, M., Monshouwer-Kloots, J. J., Devalla, H. D., Orlova, V. V., Anastassiadis, K., Mummery, C. L., Davis, R. P. & Passier, R., 12 Dec 2017, In : Stem cell reports. 9, 6, p. 1765-1779 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Ovalbumin
Stem cells
Cardiac Myocytes
Transcription Factors
Pluripotent Stem Cells

A gut-on-a-chip study: Enabling on-demand manipulation of the outer cell microenvironment in a multicompartmental 3D culture array

Gümüscü Sefünc, B., Albers, H. J., van den Berg, A., Eijkel, J. C. T. & van der Meer, A., 22 Oct 2017, 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences. Lee, A. & DeVoe, D. (eds.). The Chemical and Biological Microsystems Society, p. 1013 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Cellular Microenvironment
Hydrogel
Caco-2 Cells
Coculture Techniques
Epithelial Cells

Chipholder-integrated 3d-printed pneumatic logic controllers for microfluidic chips

Loessberg-Zahl, J. T., Vollenbroek, J. C., van der Meer, A., Eijkel, J. C. T. & van den Berg, A., 22 Oct 2017, The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences. Lee, A. & DeVoe, D. (eds.). The Chemical and Biological Microsystems Society, p. 645 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Microfluidics
Pneumatics
Controllers
Multilayers
Automation
7 Citations (Scopus)
41 Downloads (Pure)
Open Access
File
Caco-2 Cells
Microfluidics
Hydrogel
Cell Culture Techniques
Perfusion

Configurable gel geometry via flow patterning for angiogenisis assays

Loessberg-Zahl, J. T., Makkinga, D., van der Meer, A., Eijkel, J. C. T. & van den Berg, A., 22 Oct 2017, 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences. Lee, A. & D. D. (eds.). The Chemical and Biological Microsystems Society, p. 1074- 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Assays
Gels
Oncology
Geometry
Proteins
11 Downloads (Pure)

Electrical simulations and experimental results of 4-electrode AC transepithelial electrical resistance measurements in gut-on-a-chip

van der Helm, M. W., Henry, O., Hamkins-Indik, T., Cronce, M., Leineweber, W., Odijk, M., van der Meer, A. D., Eijkel, J. C. T., Ingber, D. E., van den Berg, A. & Segerink, L., 24 Oct 2017, 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences. Savannah: Chemical and Biological Microstystems Society, p. 1114-1115 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

electrical resistance
alternating current
chips
electrodes
simulation
6 Citations (Scopus)
82 Downloads (Pure)

Electrophysiological analysis of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) using multi-electrode arrays (MEAs)

Sala, L., Ward-van Oostwaard, D., Tertoolen, L. G. J., Mummery, C. L. & Bellin, M., 12 May 2017, In : Journal of visualized experiments. 2017, 123, e55587.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Pluripotent Stem Cells
Stem cells
Cardiac Myocytes
Electrodes
Induced Pluripotent Stem Cells
5 Citations (Scopus)
62 Downloads (Pure)
Open Access
File
Acoustic impedance
Electric Impedance
Electrodes
Fabrication
Equipment and Supplies
13 Citations (Scopus)
64 Downloads (Pure)

Human heart disease: lessons from human pluripotent stem cell-derived cardiomyocytes

Giacomelli, E., Mummery, C. L. & Bellin, M., 1 Oct 2017, In : Cellular and Molecular Life Sciences. 74, 20, p. 3711-3739 29 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Pluripotent Stem Cells
Cardiac Myocytes
Heart Diseases
Cardiovascular Diseases
Research
11 Citations (Scopus)
66 Downloads (Pure)

Human Pluripotent Stem Cell Differentiation into Functional Epicardial Progenitor Cells

Guadix, J. A., Orlova, V. V., Giacomelli, E., Bellin, M., Ribeiro, M. C., Mummery, C. L., Pérez-Pomares, J. M. & Passier, R., 12 Dec 2017, In : Stem cell reports. 9, 6, p. 1754-1764 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Pluripotent Stem Cells
Stem cells
Cell Differentiation
Stem Cells
Bone Morphogenetic Protein 4

Human Ventricular Stem Cell Cardiomyocytes: Validating In Vitro Assays and Screening Platforms for Pro-arrhythmia Risk Prediction

Rogers, M., Ridley, J., El-Haou, S., Williams, S., Webdale, L., Sutton, K., Stoelzle-Feix, S., Thomas, U., Fertig, N., Zwetsloot, T., Devalla, H. D. & Passier, R., 2017, In : Journal of Pharmacological and Toxicological Methods. 88, 2, p. 241-241 0237.

Research output: Contribution to journalMeeting AbstractOther research output

InPulse CrackIT Challenge: Development of An In Vitro Platform Using Physiologically Mature Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Screen for Drug-Induced Effects on Cardiac Contractility

Harris, K., Rossman, E., Xu, X., Clements, P., Mannhardt, I., Hansen, A., Saleem, U., Eschenhagen, T., Hortigon, M., Rodriguez, V. Z., Smith, G., van Meer, B., Tertoolen, L., Mummery, C., Catarino Ribeiro, M., Passier, R., de Korte, T., Vlaming, M., Braam, S., Vickers, C. & 5 othersMosqueira, D., Firth, K., Prodanov, L., George, V. & Denning, C., 2017, In : Journal of Pharmacological and Toxicological Methods. 88, 2, p. 238-238 0227.

Research output: Contribution to journalMeeting AbstractOther research output

37 Citations (Scopus)
77 Downloads (Pure)

Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: has the time come?

Sala, L., Bellin, M. & Mummery, C. L., 1 Nov 2017, In : British journal of pharmacology. 174, 21, p. 3749-3765 17 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Pluripotent Stem Cells
Cardiac Myocytes
Pharmacology
Safety
Cardiac Arrhythmias
21 Citations (Scopus)
75 Downloads (Pure)

Mimicking arterial thrombosis in a 3D-printed microfluidic in vitro vascular model based on computed tomography angiography data

Costa, P. F., Albers, H. J., Linssen, J. E. A., Middelkamp, H. H. T., van der Hout, L., Passier, R., Van Den Berg, A., Malda, J. & van der Meer, A. D., 2017, In : Lab on a chip. 17, 16, p. 2785-2792 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Angiography
Microfluidics
Tomography
Blood Vessels
Thrombosis
1 Downloads (Pure)

Modelling and drug screening for cardiovascular disease

Passier, R., Mar 2017, In : Acta physiologica. 219, S711, p. 7-7 SO2-2.

Research output: Contribution to journalSpecial issueAcademicpeer-review

4 Citations (Scopus)
1 Downloads (Pure)

Organs-on-chips for vascular function

van der Meer, A., 20 Oct 2017, In : Toxicology Letters. 280, 1, p. S29 1 p.

Research output: Contribution to journalSpecial issueAcademicpeer-review

Blood Vessels
Equipment and Supplies
Liquids
Microchannels
Human Body
6 Citations (Scopus)

Shear-sensitive nanocapsule drug release for site-specific inhibition of occlusive thrombus formation

Molloy, C. P., Yao, Y., Kammoun, H., Bonnard, T., Hoefer, T., Alt, K., Tovar-Lopez, F., Rosengarten, G., Ramsland, P. A., van der Meer, A. D., van den Berg, A., Murphy, A. J., Hagemeyer, C. E., Peter, K. & Westein, E., 1 May 2017, In : Journal of thrombosis and haemostasis. 15, 5, p. 972-982 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Nanocapsules
Thrombosis
Platelet Aggregation Inhibitors
Bleeding Time
Phosphatidylcholines
45 Citations (Scopus)
44 Downloads (Pure)

Small molecule absorption by PDMS in the context of drug response bioassays

van Meer, B. J., de Vries, H., Firth, K. S. A., van Weerd, J., Tertoolen, L. G. J., Karperien, H. B. J., Jonkheijm, P., Denning, C., IJzerman, A. P. & Mummery, C. L., 2017, In : Biochemical and biophysical research communications. 482, 2, p. 323-328 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Bioassay
Lab-On-A-Chip Devices
Biological Assay
Molecules
Microfluidics
54 Citations (Scopus)
29 Downloads (Pure)

Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells

Giacomelli, E., Bellin, M., Sala, L., Van Meer, B. J., Tertoolen, L. G. J., Orlova, V. V. & Mummery, C. L., 15 Mar 2017, In : Development (Cambridge). 144, 6, p. 1008-1017 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Pluripotent Stem Cells
Cardiac Myocytes
Endothelial Cells
Endothelium
Induced Pluripotent Stem Cells
49 Downloads (Pure)

Versatile open software to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo

Sala, L., Van Meer, B. J., Tertoolen, L. G. J., Bakkers, J., Bellin, M., Davis, R. P., Denning, C., Dieben, M. A. E., Eschenhagen, T., Giacomelli, E., Grandela, C., Hansen, A., Holman, E. R., Jongbloed, M. R. M., Kamel, S. M., Koopman, C. D., Lachaud, Q., Mannhardt, I., Mol, M. P. H., Orlova, V. V. & 6 othersPassier, R., Ribeiro, M. C., Saleem, U., Smith, G. L., Mummery, C. L. & Burton, F. L., 2017, bioRxiv.

Research output: Working paperProfessional

Open Access
File
Muscle Contraction
Cardiac Myocytes
Myocardium
Software
Heart Diseases
2016
20 Citations (Scopus)
35 Downloads (Pure)

A comprehensive gene expression analysis at sequential stages of in vitro cardiac differentiation from isolated MESP1-expressing-mesoderm progenitors

den Hartogh, S. C., Wolstencroft, K., Mummery, C. L. & Passier, R., 19 Jan 2016, In : Scientific reports. 6, 19386.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Mesoderm
Gene Expression
Pluripotent Stem Cells
Neoplastic Stem Cells
Gene Regulatory Networks
37 Citations (Scopus)
32 Downloads (Pure)

Assessment of whole blood thrombosis in a microfluidic device lined by fixed human endothelium

Jain, A., van der Meer, A. D., Papa, A-L., Barrile, R., Lai, A., Schlechter, B. L., Otieno, M. A., Louden, C. S., Hamilton, G. A., Michelson, A. D., Frelinger, A. L. & Ingber, D. E., 2016, In : Biomedical microdevices. 18, 73, p. 73- 7 p., 73.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Lab-On-A-Chip Devices
Platelets
Point-of-Care Systems
Microfluidics
Endothelium