Biomaterials Science and Technology

Research Output 1970 2019

2017
3 Citations (Scopus)
1 Downloads (Pure)

Oxygen-releasing poly(trimethylene carbonate) microspheres for tissue engineering applications

Steg, H., Buizer, A. T., Woudstra, W., Veldhuizen, A. G., Bulstra, S. K., Grijpma, D. W. & Kuijer, R., 1 Oct 2017, In : Polymers for advanced technologies. 28, 10, p. 1252-1257

Research output: Contribution to journalArticleAcademicpeer-review

Microspheres
Tissue engineering
Carbonates
Oxygen
Sterol Esterase
11 Citations (Scopus)
34 Downloads (Pure)

Pancreatic islet macroencapsulation using microwell porous membranes

Skrzypek, K., Groot Nibbelink, M., Van Lente, J., Buitinga, M., Engelse, M. A., De Koning, E. J. P., Karperien, M., Van Apeldoorn, A. & Stamatialis, D., 1 Dec 2017, In : Scientific reports. 7, 1, 9186.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Islets of Langerhans
Islets of Langerhans Transplantation
Membranes
Glucose
Equipment and Supplies
17 Citations (Scopus)
31 Downloads (Pure)

PBCA-based polymeric microbubbles for molecular imaging and drug delivery

Koczera, P., Appold, L., Shi, Y., Liu, M., Dasgupta, A., Pathak, V., Ojha, T., Fokong, S., Wu, Z., van Zandvoort, M., Iranzo, O., Kuehne, A. J. C., Pich, A., Kiessling, F. & Lammers, T., 10 Aug 2017, In : Journal of controlled release. 259, p. 128-135 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Cyanoacrylates
Microbubbles
Molecular Imaging
Pharmaceutical Preparations
Vascular Tissue Neoplasms
48 Citations (Scopus)

Pharmacological and physical vessel modulation strategies to improve EPR-mediated drug targeting to tumors

Ojha, T., Pathak, V., Shi, Y., Hennink, W. E., Moonen, C. T. W., Storm, G., Kiessling, F. & Lammers, T., 15 Sep 2017, In : Advanced drug delivery reviews. 119, p. 44-60 17 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Drug Delivery Systems
Permeability
Nanomedicine
Pharmacology
Neoplasms
3 Citations (Scopus)

Phase-separated mixed-macromer hydrogel networks and scaffolds prepared by stereolithography

Przeradzka, M. A., van Bochove, B., Bor, T. C. & Grijpma, D. W., Oct 2017, In : Polymers for advanced technologies. 28, 10, p. 1212-1218

Research output: Contribution to journalArticleAcademicpeer-review

Stereolithography
Hydrogels
Hydrogel
Scaffolds
Phase separation
36 Citations (Scopus)

Physico-Chemical Strategies to Enhance Stability and Drug Retention of Polymeric Micelles for Tumor-Targeted Drug Delivery

Shi, Y., Lammers, T. G. G. M., Storm, G. & Hennink, W. E., 2017, In : Macromolecular bioscience. 17, 1, 1600160.

Research output: Contribution to journalArticleAcademicpeer-review

Drug Stability
Micelles
Tumors
Pharmaceutical Preparations
Neoplasms
5 Citations (Scopus)

Poly(trimethylene carbonate) and nano-hydroxyapatite porous scaffolds manufactured by stereolithography

Guillaume, O., Geven, M. A., Grijpma, D. W., Tang, T. T., Qin, L., Lai, Y., Yuan, H., Richards, R. G. & Eglin, D., 1 Oct 2017, In : Polymers for advanced technologies. 28, 10, p. 1219-1225

Research output: Contribution to journalArticleAcademicpeer-review

Stereolithography
Durapatite
Hydroxyapatite
Scaffolds
Carbonates
3 Citations (Scopus)

Poly(trimethylene carbonate) as an elastic biodegradable film for human embryonic stem cell-derived retinal pigment epithelial cells

Sorkio, A., Haimi, S., Verdoold, V., Juuti-Uusitalo, K., Grijpma, D. W. & Skottman, H., Nov 2017, In : Journal of tissue engineering and regenerative medicine. 11, 11, p. 3134-3144

Research output: Contribution to journalArticleAcademicpeer-review

Retinal Pigments
Stem cells
Pigments
Carbonates
Epithelial Cells
4 Citations (Scopus)

Poly(trimethylene carbonate)-based composite materials for reconstruction of critical-sized cranial bone defects in sheep

Zeng, N., van Leeuwen, A. C., Grijpma, D. W., Bos, R. R. M. & Kuijer, R., 1 Feb 2017, In : Journal of Cranio-Maxillo-Facial Surgery. 45, 2, p. 338-346 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Sheep
Bone and Bones
Osteogenesis
Bone Regeneration
polytrimethylene carbonate

Preface

Stamatialis, D., 29 Nov 2017, Biomedical Membranes And (Bio)artificial Organs. World Scientific Publishing Co. Pte Ltd, p. vii-viii

Research output: Chapter in Book/Report/Conference proceedingForeword/postscriptAcademic

1 Citation (Scopus)
2 Downloads (Pure)

Preparation and characterization of flexible and elastic porous tubular PTMC scaffolds for vascular tissue engineering

Guo, Z., Grijpma, D. W. & Poot, A. A., 1 Oct 2017, In : Polymers for advanced technologies. 28, 10, p. 1239-1244

Research output: Contribution to journalArticleAcademicpeer-review

Scaffolds (biology)
Tissue engineering
Scaffolds
Carbonates
Molecular weight
99 Downloads (Pure)

Preparation of medical implants by stereolithography: photo-crosslinked networks and structures

van Bochove, J. B., 2 Jun 2017, Enschede. 204 p.

Research output: ThesisPhD Thesis - Research UT, graduation UTAcademic

Open Access
File
Stereolithography
Molecular weight
Degradation
Resins
Hydrogels
62 Citations (Scopus)
32 Downloads (Pure)

Rapid Continuous Multimaterial Extrusion Bioprinting

Liu, W., Zhang, Y. S., Heinrich, M. A., De Ferrari, F., Jang, HL., Bakht, SM., Alvarez, MM., Yang, J., Li, YC., Trujillo-de Stantiago, G., Miri, AK., Zhu, K., Khoshakhlagh, P., Prakash, G., Cheng, H., Guan, X., Zhong, Z., Ju, J., Zhu, GH., Jin, X. & 3 othersRyon Shin, S., Dokmeci, M. R. & Khademhosseini, A., Jan 2017, In : Advanced materials. 29, 3

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Extrusion
Fabrication
7 Citations (Scopus)
23 Downloads (Pure)

Real-Time Monitoring of Nanoparticle Formation by FRET Imaging

Sanchez-Gaytan, B. L., Fay, F., Hak, S., Alaarg, A. M. S. A., Fayad, Z. A., Perez-Medina, C., Mulder, W. J. M. & Zhao, Y., 23 Jan 2017, In : Angewandte Chemie. 56, 11, p. 2923-2926

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Energy transfer
Nanoparticles
Imaging techniques
Monitoring
Lipoproteins
1 Downloads (Pure)

Reduction sensitive nanosystems for tumor targeted imaging and therapy

Zhu, Y., 27 Oct 2017, Enschede: University of Twente. 208 p.

Research output: ThesisPhD Thesis - Research UT, graduation UTAcademic

Nanosystems
Tumors
Medical nanotechnology
Imaging techniques
Polymers
3 Citations (Scopus)

Scalable data-driven short-term traffic prediction

Friso, K., Wismans, L. J. J. & Tijink, M. B., 8 Aug 2017, 5th IEEE International Conference on Models and Technologies for Intelligent Transportation Systems, MT-ITS 2017 - Proceedings. IEEE, p. 687-692 6 p. 8005600

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Data-driven
Traffic
traffic
Prediction
Confidence interval
4 Citations (Scopus)

Status and trends in the development of clinical diagnostic agents

Opacic, T., Paefgen, V., Lammers, T. G. G. M. & Kiessling, F., 1 Jul 2017, In : Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology. 9, 4, p. e1441

Research output: Contribution to journalArticleAcademicpeer-review

Contrast Media
Computer-Assisted Surgery
Medical nanotechnology
Safety
Imaging techniques
4 Citations (Scopus)

Strategies for the Activation and Release of the Membranolytic Peptide Melittin from Liposomes Using Endosomal pH as a Trigger

Oude Blenke, E., Sleszynska, M., Evers, M. J. W., Storm, G., Martin, N. I. & Mastrobattista, E., 22 Dec 2017, In : Bioconjugate chemistry. 28, 2, p. 574-582

Research output: Contribution to journalArticleAcademicpeer-review

Melitten
Liposomes
Peptides
Chemical activation
Hydrazones
13 Citations (Scopus)
27 Downloads (Pure)

Stroma-regulated HMGA2 is an independent prognostic marker in PDAC and AAC

Strell, C., Norberg, K. J., Mezheyeuski, A., Schnittert, J., Kuninty, P. R., Moro, C. F., Paulsson, J., Schultz, N. A., Calatayud, D., Löhr, J. M., Frings, O., Verbeke, C. S., Heuchel, R. L., Prakash, J., Johansen, J. S. & Östman, A., 27 Jun 2017, In : British journal of cancer. 117, 1, p. 65-77 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Adenocarcinoma
Neoplasms
HMGA2 Protein
Pancreatic Stellate Cells
Conditioned Culture Medium
43 Citations (Scopus)
45 Downloads (Pure)

Surface Curvature Differentially Regulates Stem Cell Migration and Differentiation via Altered Attachment Morphology and Nuclear Deformation

Werner, M., Blanquer, S., Haimi, S., Korus, G., Dunlop, J. W. C., Duda, G. N., Grijpma, D. W. & Petersen, A., 1 Nov 2017, In : Advanced science. 4, 2, 1600347.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
nuclear deformation
stem cells
Stem cells
Cell Movement
attachment
20 Citations (Scopus)

Surface curvature in triply-periodic minimal surface architectures as a distinct design parameter in preparing advanced tissue engineering scaffolds

Blanquer, S. B. G., Werner, M., Hannula, M., Sharifi, S., Lajoinie, G. P. R., Eglin, D., Hyttinen, J., Poot, A. A. & Grijpma, D. W., 12 Apr 2017, In : Biofabrication. 9, 2, 025001.

Research output: Contribution to journalArticleAcademicpeer-review

Tissue Scaffolds
Porosity
Rubber
Tissue Engineering
Scaffolds (biology)
27 Citations (Scopus)

Surface-enrichment with hydroxyapatite nanoparticles in stereolithography-fabricated composite polymer scaffolds promotes bone repair

Guillaume, O., Geven, M. A., Sprecher, C. M., Stadelmann, V. A., Grijpma, D. W., Tang, T. T., Qin, L., Lai, Y., Alini, M., de Bruijn, J. D., Yuan, H., Richards, R. G. & Eglin, D., 1 May 2017, In : Acta biomaterialia. 54, p. 386-398 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Stereolithography
Durapatite
Hydroxyapatite
Scaffolds
Nanoparticles
21 Citations (Scopus)

Tailoring surface nanoroughness of electrospun scaffolds for skeletal tissue engineering

Chen, H., Huang, X., Zhang, M., Damanik, F., Baker, M., Leferink, A. M., Yuan, H., Truckenmüller, R. K., van Blitterswijk, C. & Moroni, L., 6 Jul 2017, In : Acta biomaterialia. 59, p. 82-93

Research output: Contribution to journalArticleAcademicpeer-review

Tissue Engineering
Scaffolds (biology)
Mesenchymal Stromal Cells
Tissue engineering
Osteopontin
182 Downloads (Pure)

Targeted therapeutics in inflammatory atherosclerosis

Alaarg, A. M. S. A., 8 Sep 2017, Enschede: University of Twente. 259 p.

Research output: ThesisPhD Thesis - Research UT, graduation UTAcademic

Open Access
File
Nanomedicine
Atherosclerosis
Macrophages
Cardiovascular Diseases
Therapeutics
20 Citations (Scopus)

Targeting distinct myeloid cell populations in vivo using polymers, liposomes and microbubbles

Ergen, C., Heymann, F., Al Rawashdeh, W., Gremse, F., Bartneck, M., Panzer, U., Pola, R., Pechar, M., Storm, G., Mohr, N., Barz, M., Zentel, R., Kiessling, F., Trautwein, C., Lammers, T. & Tacke, F., 1 Jan 2017, In : Biomaterials. 114, p. 106-120 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Microbubbles
Liposomes
Myeloid Cells
Liver
Macrophages
53 Citations (Scopus)
30 Downloads (Pure)

Targeting iron metabolism in drug discovery and delivery

Crielaard, B. J., Lammers, T. & Rivella, S., 1 Jun 2017, In : Nature Reviews Drug Discovery. 16, 6, p. 400-423 24 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Drug Discovery
Iron
Biochemical Phenomena
Neurodegenerative Diseases
Homeostasis
44 Citations (Scopus)

The battle of “nano” paclitaxel

Sofias, A. M., Dunne, M., Storm, G. & Allen, C., 1 Dec 2017, In : Advanced drug delivery reviews. 122, p. 20-30 11 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Paclitaxel
Pharmaceutical Preparations
Doxorubicin
Cisplatin
Albumins
3 Citations (Scopus)
32 Downloads (Pure)

The effect of tissue surface modification with collagenase and addition of TGF-β3 on the healing potential of meniscal tears repaired with tissue glues in vitro

Bochynska, A., Hannink, G., Verhoeven, R., Grijpma, D. W. & Buma, P., 2017, In : Journal of materials science. Materials in medicine. 28, 1, 22.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Glues
Collagenases
Tears
Adhesives
Surface treatment

The role of thromboxane A2 in complement activation-related pseudoallergy

Fülöp, T. G., Metselaar, J. M., Storm, G. & Szebeni, J., 1 Apr 2017, In : European journal of nanomedicine. 9, 2, p. 59-67 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Thromboxane A2
Complement Activation
complement
Eicosanoids
Chemical activation
3 Citations (Scopus)

The zebrafish embryo as a model to quantify early inflammatory cell responses to biomaterials

Zhang, X., Stockhammer, O. W., de Boer, L., Vischer, N. O. E., Spaink, H. P., Grijpma, D. W. & Zaat, S. A. J., 1 Sep 2017, In : Journal of biomedical materials research. Part A. 105, 9, p. 2522-2532 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Biocompatible Materials
Microspheres
Biomaterials
Macrophages
Polystyrenes
12 Citations (Scopus)
41 Downloads (Pure)

Topography of calcium phosphate ceramics regulates primary cilia length and TGF receptor recruitment associated with osteogenesis

Zhang, J., Dalbay, M. T., Luo, X., Vrij, E. J., Barbieri, D., Moroni, L., de Bruijn, J. D., van Blitterswijk, C. A., Chapple, J. P., Knight, M. M. & Yuan, H., 15 Jul 2017, In : Acta biomaterialia. 57, p. 487-497 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Cilia
Calcium phosphate
Ceramics
Osteogenesis
Topography
3 Citations (Scopus)
2 Downloads (Pure)

Triblock copolymers based on ε-caprolactone and trimethylene carbonate for the 3D printing of tissue engineering scaffolds

Güney, A., Malda, J., Dhert, W. J. A. & Grijpma, D. W., 2017, In : International journal of artificial organs. 40, 4, p. 176-184 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Tissue Scaffolds
Tissue Engineering
Scaffolds (biology)
Tissue engineering
Block copolymers
29 Citations (Scopus)
38 Downloads (Pure)

Tumor-targeted nanomedicines for cancer theranostics

Arranja, A. G., Pathak, V., Lammers, T. & Shi, Y., 1 Jan 2017, In : Pharmacological Research. 115, p. 87-95 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Nanomedicine
Pharmaceutical Preparations
Neoplasms
Micelles
Therapeutic Uses
7 Citations (Scopus)

Tunable and processable shape memory composites based on degradable polymers

Zhang, X., Geven, M. A., Grijpma, D. W., Peijs, T. & Gautrot, J. E., 28 Jul 2017, In : Polymer. 122, p. 323-331 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Shape memory effect
Polymers
Composite materials
Scaffolds
Lactic acid
15 Citations (Scopus)
38 Downloads (Pure)

Tyrosine kinase inhibitor BIBF1120 ameliorates inflammation, angiogenesis and fibrosis in CCl4-induced liver fibrogenesis mouse model

Öztürk Akcora, B., Storm, G., Prakash, J. & Bansal, R., 2017, In : Scientific reports. 7, 44545.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Protein-Tyrosine Kinases
Fibrosis
Inflammation
Liver
Hepatic Stellate Cells
2016

14th European Symposium on Controlled Drug Delivery

Paulusse, J. M. J., ten Hoopen, H. W. M., Hendriks, K. G., Engbersen, J. F. J., Hennink, W. & de Smedt, S. C., 13 Apr 2016, Egmond aan Zee, Hotel Zuiderduin

Research output: Other contributionOther research output

2 Citations (Scopus)

Advanced Functional Polymers for Medicine

Neffe, A. T., Grijpma, D. W. & Lendlein, A., 1 Dec 2016, In : Macromolecular bioscience. 16, 12, p. 1743-1744 2 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Functional polymers
Medicine
Polymers

Advanced Functional Polymers in Medicine seminar 2016 (AFPM)

ten Hoopen, H. W. M., Hendriks, K. G., Neffe, A., Benner, S., Lendlein, A. & Grijpma, D. W., 15 Jun 2016, Enschede, ICSC Drienerburght, Utwente

Research output: Other contributionOther research output

AFPM2016 Abstract Book

Grijpma, D. W. & ten Hoopen, H. W. M., 2016, Enschede: UT-Dept Biomaterials Science and Technology.

Research output: Book/ReportBook editingPopular

7 Citations (Scopus)

Amphiphilic Phospholipid-Based Riboflavin Derivatives for Tumor Targeting Nanomedicines

Beztsinna, N., Tsvetkova, Y., Bartneck, M., Lammers, T. G. G. M., Kiessling, F. & Bestel, I., 2016, In : Bioconjugate chemistry. 27, 9, p. 2048-2061

Research output: Contribution to journalArticleAcademicpeer-review

Nanomedicine
Medical nanotechnology
Riboflavin
Liposomes
Phospholipids
34 Citations (Scopus)
69 Downloads (Pure)

Bioengineered kidney tubules efficiently excrete uremic toxins

Jansen, J., Fedecostante, M., Wilmer, M., Peters, J. G., Kreuser, U. M., Broek, P. H., Mensink, R. A., Boltje, T. J., Stamatialis, D., Wetzels, J. F., van der Heuvel, L. P., Hoenderop, J. G. & Masereeuw, R., 2016, In : Scientific reports. 6, 26715, 26715.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Kidney Tubules
Kidney
Indican
BRCA1 Protein
Organic Anion Transporters
11 Citations (Scopus)
87 Downloads (Pure)

Biomaterials for the treatment of Alzheimer’s disease

Hadavi, D. & Poot, A. A., 2016, In : Frontiers in bioengineering and biotechnology. 4, 49, p. - 10 p., 49.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Biocompatible Materials
Biomaterials
Alzheimer Disease
Neurodegenerative diseases
Therapeutics
158 Downloads (Pure)

Bioreducible polycationic gene vectors

Si, G., 20 Jan 2016, Enschede: Universiteit Twente. 203 p.

Research output: ThesisPhD Thesis - Research UT, graduation UTAcademic

File
23 Citations (Scopus)

Bioresponsive and fluorescent hyaluronic acid-iodixanol nanogels for targeted X-ray computed tomography imaging and chemotherapy of breast tumors

Zhu, Y., Wang, X., Wang, X., Chen, J., Meng, F., Deng, D., Cheng, R., Feijen, J. & Zhong, Z., 2016, In : Journal of controlled release. 24, part B, p. 229-239

Research output: Contribution to journalArticleAcademicpeer-review

X Ray Computed Tomography
Hyaluronic Acid
Breast Neoplasms
Drug Therapy
Paclitaxel
14 Citations (Scopus)

Cancer-Associated Fibroblasts: Perspectives in Cancer Therapy

Prakash, J., 2016, In : Trends in cancer. 2, 6, p. 277-279

Research output: Contribution to journalArticleAcademicpeer-review

Neoplasms
Stromal Cells
Carcinogenesis
Therapeutics
Neoplasm Metastasis
65 Citations (Scopus)
31 Downloads (Pure)

Cancer nanomedicine: is targeting our target?

Lammers, T., Kiessling, F., Ashford, M., Hennink, W., Crommelin, D. & Storm, G., 7 Sep 2016, In : Nature materials. 1, 9, 16069.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Medical nanotechnology
delivery
cancer
217 Citations (Scopus)
44 Downloads (Pure)

Cells release subpopulations of exosomes with distinct molecular and biological properties

Willms, E., Johansson, H. J., Mäger, I., Lee, Y., Blomberg, K. E. M., Sadik, M., Alaarg, A. M. S. A., Smith, C. I. E., Lehtio, J., El Andaloussi, S., Wood, M. J. A. & Vader, P., 2016, In : Scientific reports. 6, 22519, 22519.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Exosomes
Density Gradient Centrifugation
Proteomics
Dissection
RNA
26 Citations (Scopus)
383 Downloads (Pure)

Clinical Advancements in the Targeted Therapies against Liver Fibrosis

Bansal, R., Nagorniewicz, B. P. & Prakash, J., 2016, In : Mediators of inflammation. 2016, 7629724, p. - 16 p., 7629724.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
15 Citations (Scopus)

Comparison of pharmaceutical nanoformulations for curcumin: enhancement of aqueous solubility and carrier retention

Allijn, I. E., Schiffelers, R. M. & Storm, G., 2016, In : International journal of pharmaceutics. 506, 1/2, p. 407-413 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Curcumin
Solubility
Pharmaceutical Preparations
Nanoparticles
Spices