Biomaterials Science and Technology

Research Output 1970 2019

2016
13 Citations (Scopus)
1 Downloads (Pure)

Polymer-polymer composites for the design of strong and tough degradable biomaterials

Zhang, X., Geven, M. A., Grijpma, D. W., Gautrot, J. & Peijs, T., 2016, In : Materials today communications. 8, p. 53-63

Research output: Contribution to journalArticleAcademicpeer-review

Biocompatible Materials
Biomaterials
Polymers
Fibers
Composite materials
11 Citations (Scopus)
38 Downloads (Pure)

Preclinical detection of liver fibrosis using dual-modality photoacoustic/ultrasound system

van den Berg, P. J., Bansal, R., Daoudi, K., Steenbergen, W. & Prakash, J., 2016, In : Biomedical optics express. 7, 12, p. 5081-5091

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
fibrosis
liver
Liver Cirrhosis
Liver
angiogenesis
4 Citations (Scopus)
1 Downloads (Pure)
Graphite
Oxides
Graphene
Carbonates
Composite materials
11 Citations (Scopus)

Preparation of Designed Poly(trimethylene carbonate) Meniscus Implants by Stereolithography: Challenges in Stereolithography

van Bochove, B., Hannink, G., Buma, P. & Grijpma, D. W., 2016, In : Macromolecular bioscience. 16, 12, p. 1853-1863

Research output: Contribution to journalArticleAcademicpeer-review

Stereolithography
Carbonates
Resins
Coloring Agents
Methacrylates
38 Citations (Scopus)

Quantitative micro-computed tomography imaging of vascular dysfunction in progressive kidney diseases

Ehling, J., Babickova, J., Gremse, F., Klinkhammer, B. M., Baetke, S., Knuechel, R., Kiessling, F., Floege, J., Lammers, T. & Boor, P., 2016, In : Journal of the American Society of Nephrology. 27, 2, p. 520-532

Research output: Contribution to journalArticleAcademicpeer-review

Kidney Diseases
Blood Vessels
Tomography
Kidney
Fibrosis
10 Citations (Scopus)
140 Downloads (Pure)

Radionuclide imaging of liposomal drug delivery

van der Geest, T., Laverman, P., Metselaar, J. M., Storm, G. & Boerman, O. C., 2016, In : Expert opinion on drug delivery. 13, 9, p. 1231-1242

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Liposomes
Radionuclide Imaging
Pharmaceutical Preparations
Drug Monitoring
Expert Testimony
23 Citations (Scopus)
72 Downloads (Pure)

Regeneration of the lung: Lung stem cells and the development of lung mimicking devices

Schilders, K., Eenjes, E., van Riet, S., Poot, A. A., Stamatialis, D., Truckenmüller, R. K., Hiemstra, P. & Rottier, R., 2016, In : Respiratory research. 17, 44, p. -

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Regeneration
Stem Cells
Equipment and Supplies
Lung
Lung Volume Measurements

Scientists get closer to developing bioartificial kidney (PRESS RELEASE)

Stamatialis, D., Feheley, C. & Henkel, B., 19 Nov 2016

Research output: Non-textual formWeb publication/siteOther research output

40 Citations (Scopus)

Sonoporation enhances liposome accumulation and penetration in tumors with low EPR

Theek, B., Baues, M., Ojha, T., Möckel, D., Veettil, S. K., Steitz, J., van Bloois, L., Storm, G., Kiessling, F. & Lammers, T. G. G. M., 2016, In : Journal of controlled release. 231, p. 77-85

Research output: Contribution to journalArticleAcademicpeer-review

Liposomes
Permeability
Microbubbles
Neoplasms
Drug Delivery Systems
18 Citations (Scopus)
37 Downloads (Pure)

Squamous Cell Carcinoma Xenografts: Use of VEGFR2-targeted Microbubbles for Combined Functional and Molecular US to Monitor Antiangiogenic Therapy Effects

Baetke, S. C., Rix, A., Tranquart, F., Schneider, R., Lammers, T., Kiessling, F. & Lederle, W., 2016, In : Radiology. 278, 2, p. 430-440

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Microbubbles
Vascular Endothelial Growth Factor Receptor-2
Heterografts
Squamous Cell Carcinoma
Ultrasonography
81 Citations (Scopus)

Strategies for encapsulation of small hydrophilic and amphiphilic drugs in PLGA microspheres: State-of-the-art and challenges

Ramazani, F., Chen, W., van Nostrum, C. F., Storm, G., Kiessling, F., Lammers, T. G. G. M., Hennink, W. E. & Kok, R. J., 2016, In : International journal of pharmaceutics. 499, 1-2, p. 358-367

Research output: Contribution to journalArticleAcademicpeer-review

Microspheres
Drug Compounding
Oils
Water
Pharmaceutical Preparations

Studying nanoparticle-3D tumour spheroid interactions in a microfluidic format: towards the assessment of drug delivery to complex tumour tissues under physiological conditions

Blondé, J-BG., Babu, D., Priwitaningrum, D. L., Sridhar, A., Prakash, J. & le Gac, S., 9 Oct 2016, p. -.

Research output: Contribution to conferencePosterOther research output

8 Citations (Scopus)

Submicron-surface structured tricalcium phosphate ceramic enhances the bone regeneration in canine spine environment

Duan, R., Barbieri, D., Luo, X., Weng, J., de Bruijn, J. D. & Yuan, H., 2016, In : Journal of orthopaedic research. 34, 11, p. 1865-1873

Research output: Contribution to journalArticleAcademicpeer-review

Bone Regeneration
Canidae
Spine
Osteogenesis
Bone and Bones
9 Citations (Scopus)

Surfactant-free Preparation of Highly Stable Zwitterionic Poly(amido amine) Nanogels with Minimal Cytotoxicity

Ekkelenkamp, A. E., Jansman, M. M. T., Roelofs-Haarhuis, H. M., Engbersen, J. F. J. & Paulusse, J. M. J., 2016, In : Acta biomaterialia. 30, p. 126-134

Research output: Contribution to journalArticleAcademicpeer-review

Cytotoxicity
Surface charge
Surface-Active Agents
Amines
Surface active agents
10 Citations (Scopus)
1 Downloads (Pure)
Hydrogels
Cell adhesion
Polyethylene glycols
Hydrogel
Cell proliferation
13 Citations (Scopus)

Tailoring the physicochemical properties of core-crosslinked polymeric micelles for pharmaceutical applications

Hu, Q., Rijcken, C. J. F., Gaal, E., Brundel, P., Kostkova, H., Etrych, T., Weber, B., Barz, M., Kiessling, F., Prakash, J., Storm, G., Hennink, W. E. & Lammers, T. G. G. M., 2016, In : Journal of controlled release. 244, part B, p. 314-325

Research output: Contribution to journalArticleAcademicpeer-review

Micelles
docetaxel
Pharmaceutical Preparations
Nanomedicine
Clinical Trials, Phase I
3 Citations (Scopus)

Targeting cellular and microenvironmental multidrug resistance

Tezcan, O., Ojha, T., Storm, G., Kiessling, F. & Lammers, T. G. G. M., 2016, In : Expert opinion on drug delivery. 13, 9, p. 1199-1202

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)
49 Downloads (Pure)

The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance

Gautheron, J., Vucur, M., Schneider, A. T., Severi, I., Lammers, T. G. G. M., Heikenwalder, LM. & Luedde, T., 2016, In : Nature communications. 7, 11869, p. 11869- 11869.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Receptor-Interacting Protein Serine-Threonine Kinases
adipose tissues
White Adipose Tissue
Glucose Intolerance
glucose

The potential application of LIPUS and PEMF on cartilage and chondrogenic differentiation; an in vitro study

Tan, L., 7 Dec 2016, Groningen: UMCG. 98 p.

Research output: ThesisPhD Thesis - Research external, graduation externalAcademic

67 Downloads (Pure)

The preclinical development of novel treatment options for advanced prostate cancer

Kroon, J., 20 Jan 2016, Enschede: Universiteit Twente. 160 p.

Research output: ThesisPhD Thesis - Research external, graduation UTAcademic

File
docetaxel
Prostatic Neoplasms
Dexamethasone
Glucocorticoid Receptors
Therapeutics
22 Citations (Scopus)
12 Downloads (Pure)

Tissue adhesives for meniscus tear repair: an overview of current advances and prospects for future clinical solutions

Bochyńska, A. I., Hannink, G., Grijpma, D. W. & Buma, P., 2016, In : Journal of materials science. Materials in medicine. 27, 5, 85.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Tissue Adhesives
Tears
Adhesives
Repair
Tissue
133 Downloads (Pure)

Topochip: technology for instructing cell fate and morphology via designed surface topography

Hulshof, G. F. B., 26 May 2016, Enschede: Universiteit Twente. 140 p.

Research output: ThesisPhD Thesis - Research UT, graduation UTAcademic

File
Technology
Bone and Bones
Orthopedics
Artificial Kidneys
Cell Shape
7 Citations (Scopus)
1 Downloads (Pure)

Tough biodegradable mixed-macromer networks and hydrogels by photo-crosslinking in solution

Zant, E. & Grijpma, D. W., 2016, In : Acta biomaterialia. 31, p. 80-88

Research output: Contribution to journalArticleAcademicpeer-review

Hydrogels
Ethylene Glycol
Crosslinking
Polyethylene glycols
Carbonates
29 Citations (Scopus)
1 Downloads (Pure)

Tumor stroma-containing 3D spheroid arrays: A tool to study nanoparticle penetration

Priwitaningrum, D. L., Priwitaningrum, D. L., Blondé, J-B. G. M., Blonde, J-B. G., Sridhar, A., van Baarlen, J., Hennink, W. E., Storm, G., le Gac, S. & Prakash, J., 2016, In : Journal of controlled release. 244, part B, p. 257-268

Research output: Contribution to journalArticleAcademicpeer-review

Nanoparticles
Neoplasms
Silicon Dioxide
Fibroblasts
3T3 Cells
36 Citations (Scopus)

Ultrasound-mediated drug delivery to the brain: principles, progress and prospects

Dasgupta, I., Liu, M., Ojha, T., Storm, G., Kiessling, F. & Lammers, T. G. G. M., 2016, In : Drug discovery today. 20, p. 41-48

Research output: Contribution to journalArticleAcademicpeer-review

Microbubbles
Nanomedicine
Brain
Neurodegenerative Diseases
Pharmaceutical Preparations
21 Citations (Scopus)
3 Downloads (Pure)

Upscaling of a living membrane for bioartificial kidney device

Chevtchik, N., Fedecostante, M., Jansen, J., Mihajlovic, M., Wilmer, M., Rüth, M., Masereeuw, R. & Stamatialis, D., 2016, In : European journal of pharmacology. 790, p. 28-35

Research output: Contribution to journalArticleAcademicpeer-review

Kidney
Equipment and Supplies
Membranes
Waste Products
Epithelial Cells
17 Citations (Scopus)
111 Downloads (Pure)

UV cross-linkable graphene/poly(trimethylene carbonate) composites for 3D printing of electrically conductive scaffolds

Sayyar, S., Bjorninen, M., Haimi, S., Miettinen, S., Gilmore, K., Grijpma, D. W. & Wallace, G., 2016, In : ACS applied materials & interfaces. 8, 46, p. 31916-31925

Research output: Contribution to journalArticleAcademicpeer-review

File
Graphite
Stem cells
Scaffolds
Graphene
Printing
82 Downloads (Pure)

Zwitterionic poly(amido-amine) based nanogels

Ekkelenkamp, A. E., 7 Dec 2016, Enschede: UT Universiteit Twente - TNW - MIRA -BST. 161 p.

Research output: ThesisPhD Thesis - Research UT, graduation UTAcademic

File
Amines
Imaging techniques
Controlled drug delivery
Nanoparticles
Peptidomimetics
2015
15 Citations (Scopus)

[18]F FDG PET/CT imaging to monitor the therapeutic effect of liposome-encapsulated prednisolone in experimental rheumatoid arthritis

van der Geest, T., Metselaar, J. M., Gerrits, D., van Lent, P. L., Storm, G., Laverman, P. & Boerman, O. C., 2015, In : Journal of controlled release. 209, p. 20-26

Research output: Contribution to journalArticleAcademicpeer-review

Experimental Arthritis
Therapeutic Uses
Prednisolone
Liposomes
Arthritis
16 Citations (Scopus)

A Biodegradable Glue for Annulus Closure: Evaluation of Strength and Endurance

Vergroesen, P. P. A., Bochynska, A., Emanuel, K. S., Sharifi, S., Kingma, I., Grijpma, D. W. & Smit, T. H., 2015, In : Spine. 40, 9, p. 622-628

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)
2 Downloads (Pure)

A Combinatorial Photocrosslinking Method for the Preparation of Porous Structures with Widely Differing Properties

Zant, E., Blokzijl, M. & Grijpma, D. W., 2015, In : Macromolecular rapid communications. 36, 21, p. 1902-1909

Research output: Contribution to journalArticleAcademicpeer-review

41 Citations (Scopus)

A combined biomaterial and cellular approach for annulus fibrosus rupture repair

Pirvu, T., Blanquer, S., Benneker, L., Grijpma, D. W., Richards, R., Alini, M., Eglin, D., Grad, S. & Li, Z., 2015, In : Biomaterials. 42, 1, p. 11-19

Research output: Contribution to journalArticleAcademicpeer-review

Biocompatible Materials
Biomaterials
Rupture
Gene Expression Regulation
Repair
8 Citations (Scopus)

A field cancellation signal extraction method for magnetic particle imaging

Schulz, V., Straub, M., Mahlke, M., Hubertus, S., Lammers, T. G. G. M. & Kiessling, F., 2015, In : IEEE transactions on magnetics. 51, 2, p. 6501804- 6501804.

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)

Alginate microgels loaded with temperature sensitive liposomes for magnetic resonance imageable drug release and microgel visualization

van Elk, M., Lorenzato, C., Ozbakir, B., Oerlemans, C., Storm, G., Nijsen, F., Deckers, R., Vermonden, T. & Hennink, W. E., 2015, In : European polymer journal. 72, p. 620-631

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)
49 Downloads (Pure)

Alginate microspheres containing temperature sensitive liposomes (TSL) for MR-guided embolization and triggered release of doxorubicin

van Elk, M., Ozbakir, B., Barten-Rijbroek, A. D., Storm, G., Nijsen, F., Hennink, W. E., Vermonden, T. & Deckers, R., 2015, In : PLoS ONE. 10, 11, p. e0141626- e141626.

Research output: Contribution to journalArticleAcademicpeer-review

File
doxorubicin
alginates
Microspheres
Liposomes
Doxorubicin

Amsterdamse Startups krijgen onvoldoende steun (QuantiS-dot bv)

Paulusse, J. M. J. & Fritschy, Y., 2015, In : Folia. p. -

Research output: Contribution to journalArticlePopular

Open Access
35 Citations (Scopus)

Analysis of high-throughput screening reveals the effect of surface topographies on cellular morphology

Hulsman, M., Hulshof, G. F. B., Unadkat, H. V., Papenburg, B. J., Stamatialis, D., Truckenmüller, R. K., van Blitterswijk, C., de Boer, J. & Reinders, M. J. T., 10 Feb 2015, In : Acta biomaterialia. 15, p. 29-38

Research output: Contribution to journalArticleAcademicpeer-review

Surface topography
Screening
Throughput
Biocompatible Materials
Biomaterials
8 Citations (Scopus)
1 Downloads (Pure)

A new poly(1,3-trimethylene carbonate) film provides effective adhesion reduction after major abdominal surgery in a rat model

Vogels, R. R. M., Bosmans, J. W. A. M., van Barneveld, K. W. Y., Verdoold, V., van Rijn, S., Gijbels, M. J. J., Penders, J., Breukink, S., Grijpma, D. W. & Bouvy, N. D., 2015, In : Surgery. 157, 6, p. 1113-1120

Research output: Contribution to journalArticleAcademicpeer-review

Anastomotic Leak
Carboxymethylcellulose Sodium
Animal Models
Control Groups
Punctures
6 Downloads (Pure)

A new role for CD4+CD25+ regulatory T cells in promoting development of fibrosis in HCV nonstructural 3/4A transgenic mice

Bansal, R., Frelin, L. & Sällberg, M., 2015, In : Journal of viral hepatitis. 22, Suppl. S3, p. - P24.

Research output: Contribution to journalArticleAcademicpeer-review

File

Anhydrous biocompatible composite materials

Barrere-de Groot, F., Barbieri, D., Grijpma, D. W. & de Bruijn, J. D., 12 Mar 2015, (In preparation) Patent No. P107275, Priority date 12 Mar 2015

Research output: PatentProfessional

18 Citations (Scopus)

A novel approach for the intravenous delivery of leuprolide using core-cross-linked polymeric micelles

Hu, Q., van Gaal, E. V. B., Brundel, P., Ippel, E., Hackeng, T., Rijcken, C. J., Storm, G., Hennink, W. E. & Prakash, J., 2015, In : Journal of controlled release. 205, p. 98-108

Research output: Contribution to journalArticleAcademicpeer-review

Leuprolide
Micelles
Peptides
Esters
Pharmacokinetics
75 Citations (Scopus)

Antimicrobial delivery systems for local infection prophylaxis in orthopedic- and trauma surgery

ter Boo, G. A., Grijpma, D. W., Moriarty, T. F., Richards, R. G. & Eglin, D., 2015, In : Biomaterials. 52, p. 113-125

Research output: Contribution to journalArticleAcademicpeer-review

Orthopedics
Antibiotics
Surgery
Anti-Bacterial Agents
Wounds and Injuries
98 Citations (Scopus)
35 Downloads (Pure)

Applications of nanoparticles for diagnosis and therapy of cancer

Baetke, S., Lammers, T. G. G. M. & Kiessling, F., 2015, In : British journal of radiology. 88, 1054, p. 20150207-

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
14 Downloads (Pure)

Artificial organs with natural intelligence

Stamatialis, D., 2015, In : MIRA magazine. 3, p. 17-18

Research output: Contribution to journalArticleAcademic

File

A stable and remote 111In-labeling of DTPA-DSPE long-circulating liposomes

Geest, T., Gerrits, D., Franssen, G. M., Metselaar, J. M. & Storm, G., 10 Oct 2015, p. S494-S495.

Research output: Contribution to conferenceAbstractOther research output

49 Citations (Scopus)

Atherosclerotic plaque targeting mechanism of long-circulating nanoparticles established by multimodal imaging

Lobatto, M. E., Calcagno, C., Millon, A., Senders, M. L., Fay, F., Robson, P. M., Ramachandran, S., Binderup, T., Paridaans, M. P. M., Sensarn, S., Rogalla, S., Gordon, R. E., Cardos, L., Storm, G., Metselaar, J. M., Contag, C. H., Stroes, E. S. G., Fayad, Z. A. & Mulder, W. J. M., 2015, In : ACS nano. 9, 2, p. 1837-1847

Research output: Contribution to journalArticleAcademicpeer-review

arteriosclerosis
Nanoparticles
Imaging techniques
nanoparticles
vessels
26 Citations (Scopus)

Biodegradable glycopolymer-b-poly(ε-caprolactone) block copolymer micelles: Versatile construction, tailored lactose functionality, and hepatoma-targeted drug delivery

Chen, W., Meng, F., Cheng, R., Deng, C., Feijen, J. & Zhong, Z., 2015, In : Journal of materials chemistry. B: materials for biology and medicine. 3, 11, p. 2308-2317

Research output: Contribution to journalArticleAcademicpeer-review

Micelles
Lactose
Doxorubicin
Block copolymers
Acids
1 Citation (Scopus)

Cationic polymers for intracellular delivery of proteins

Coué, G. M. J. P. C. & Engbersen, J. F. J., 2015, Cationic polymers in regenerative medicine. Samal, S. & Dubruel, P. (eds.). Royal Society of Chemistry, p. 356-365 (RSC polymer chemistry series; no. 13).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

49 Citations (Scopus)

Coating nanocarriers with hyaluronic acid facilitates intravitreal drug delivery for retinal gene therapy

Martens, T. F., Remaut, K., Deschout, H., Engbersen, J. F. J., Hennink, W. E., van Steenbergen, M. J., Demeester, J., de Smedt, S. C. & Braeckmans, K., 2015, In : Journal of controlled release. 202, p. 83-92

Research output: Contribution to journalArticleAcademicpeer-review

Hyaluronic Acid
Genetic Therapy
Pharmaceutical Preparations
Vitreous Body
Molecular Weight
10 Citations (Scopus)

Comparison of three remote radiolabelling methods for long-circulating liposomes

van der Geest, T., Laverman, P., Gerrits, D., Franssen, M., Metselaar, J. M., Storm, G. & Boerman, O. C., 2015, In : Journal of controlled release. 220, Part A, p. 239-244

Research output: Contribution to journalArticleAcademicpeer-review