Biomaterials Science and Technology

Research Output 1970 2019

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Article
2016
8 Citations (Scopus)
32 Downloads (Pure)

Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice

Poosti, F., Bansal, R., Yazdani, S., Prakash, J., Beljaars, L., van den Born, J., de Borst, M. H., van Goor, H., Hillebrands, J-L. & Poelstra, K., 2016, In : Oncotarget. 7, 34, p. 54240-54252

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Peptidomimetics
Ureteral Obstruction
Myofibroblasts
Ureter
Interferon-gamma
7 Citations (Scopus)

Liposomal doxorubicin: the good, the bad and the not-so-ugly

Szebeni, J., Fülöp, G., Dézsi, L., Metselaar, J. M. & Storm, G., 2016, In : Journal of drug targeting. 24, 9, p. 765-767

Research output: Contribution to journalArticleAcademicpeer-review

Hypersensitivity
Nanomedicine
Pharmaceutical Preparations
Pharmacology
Drug Therapy
10 Citations (Scopus)

Liposomal prednisolone inhibits tumor growth in a spontaneous mouse mammary carcinoma model

Deshantri, A. K., Kooijmans, S. A. A., Kuijpers, S. A., Coimbra, M., Hoeppener, A., Storm, G., Fens, M. H. A. M. & Schiffelers, R. M., 2016, In : Journal of controlled release. 243, p. 243-249

Research output: Contribution to journalArticleAcademicpeer-review

Prednisolone
Breast Neoplasms
Growth
Neoplasms
MicroRNAs
7 Citations (Scopus)
37 Downloads (Pure)

Liposomal prednisolone inhibits vascular inflammation and enhances venous outward remodeling in a murine arteriovenous fistula model

Wong, C., Bezhaeva, T., Rothuizen, T. C., Metselaar, J. M., de Vries, M. R., Verbeek, F. P. R., Vahrmeijer, A. L., Wezel, A., Zonneveld, A-J., Rabelink, T. J., Quax, P. H. A. & Rotmans, J., 2016, In : Scientific reports. 6, 10 p., 30439.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Arteriovenous Fistula
Prednisolone
Blood Vessels
Inflammation
Tunica Intima
19 Citations (Scopus)

Liposomal prednisolone promotes macrophage lipotoxicity in experimental atherosclerosis

van der Valk, F. M., Schulte, D. M., Meiler, S., Tang, J., Zheng, K. H., van den Bossche, J., Seijkens, T., Laudes, M., de Winther, M., Lutgens, E., Alaarg, A. M. S. A., Metselaar, J. M., Dallinga-Thie, G. M., Mulder, W. J. M., Stroes, E. S. G. & Hamers, A. A. J., 2016, In : Nanomedicine : nanotechnology, biology and medicine. 12, 6, p. 1463-1470

Research output: Contribution to journalArticleAcademicpeer-review

Macrophages
Prednisolone
Atherosclerosis
Nanoparticles
Lipids
6 Citations (Scopus)

Locoregional cancer therapy using polymer-based drug depots

Ramazani, F., van Nostrum, C. F., Storm, G., Kiessling, F., Lammers, T. G. G. M., Hennink, W. E. & Kok, R. J., 2016, In : Drug discovery today. 21, 4, p. 640-647

Research output: Contribution to journalArticleAcademicpeer-review

Polymers
Pharmaceutical Preparations
Neoplasms
Liver Neoplasms
Therapeutics
11 Citations (Scopus)

Main-chain degradable single-chain cyclized polymers as gene delivery vectors

Gao, Y., Böhmer, V. I., Zhou, D., Zhao, T., Wang, W. & Paulusse, J. M. J., 2016, In : Journal of controlled release. 244, Part B, p. 375-383

Research output: Contribution to journalArticleAcademicpeer-review

Nanoparticles
Polymers
Genes
Cyclization
Polymerization
26 Citations (Scopus)

Mechanical restoration and failure analyses of a hydrogel and scaffold composite strategy for annulus fibrosus repair

Long, R. G., Bürki, A., Zysset, P., Eglin, D., Grijpma, D. W., Blanquer, S., Hecht, A. C. & Iatridis, J. C., 2016, In : Acta biomaterialia. 30, p. 116-125

Research output: Contribution to journalArticleAcademicpeer-review

Hydrogel
Hydrogels
Scaffolds
Restoration
Fibrin
56 Citations (Scopus)
25 Downloads (Pure)

MicorRNA targeting to modulate tumor microenvironment

Kuninty, P. R., Schnittert, J., Storm, G. & Prakash, J., 2016, In : Frontiers in oncology. 6, 3, p. - 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Tumor Microenvironment
MicroRNAs
Stromal Cells
Neoplasms
Small Untranslated RNA
2 Citations (Scopus)

Micro-computed tomography (μCT) as a novel method in ecotoxicology - determination of morphometric and somatic data in rainbow trout (Oncorhynchus mykiss)

Brinkmann, M., Rizzo, L. Y., Lammers, T. G. G. M., Gremse, F., Schiwy, S., Kiessling, F. & Hollert, H., 2016, In : Science of the total environment. 543, Part A, p. 135-139

Research output: Contribution to journalArticleAcademicpeer-review

34 Citations (Scopus)
12 Downloads (Pure)

MicroRNA-199a and -214 as potential therapeutic targets in pancreatic stellate cells in pancreatic tumo

Kuninty, P. R., Bojmar, L., Tjomsland, V., Larsson, M., Storm, G., Östman, A., Sandström, P. & Prakash, J., 2016, In : Oncotarget. 7, 13, p. 16396-16408

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Pancreatic Stellate Cells
MicroRNAs
Pancreatic Neoplasms
Therapeutics
Neoplasms
19 Citations (Scopus)
34 Downloads (Pure)

Modeling BCR-ABL and MLL-AF9 leukemia in a human bone marrow-like scaffold-based xenograft mode

Sontakke, P., Carretta, M., Jaques, J., Brouwers-Vos, A. Z., Lubbers-Aalders, L., Yuan, H., de Bruijn, J. D., Martens, ACM., Vellenga, E., Groen, R. W. J. & Schuringa, J. J., 2016, In : Leukemia. 30, 10, p. 2064-2073

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Heterografts
Leukemia
Bone Marrow
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Acute Myeloid Leukemia
5 Citations (Scopus)
4 Downloads (Pure)

Mold-based application of laser-induced periodic surface structures (LIPPS) on biomaterials for nanoscale patterning

Hendrikson, W. J., Masman-Bakker, W., van Bochove, B., Skolski, J. Z. P., Eichstädt, J., Koopman, H. F. J. M., van Blitterswijk, C., Grijpma, D. W., Römer, G. R. B. E., Moroni, L. & Rouwkema, J., 3 Sep 2016, In : Macromolecular bioscience. 16, 1, p. 43-49 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Biocompatible Materials
Biomaterials
Surface structure
Lasers
Fungi
4 Citations (Scopus)

Multiple pathway assessment to predict anti-atherogenic efficacy of drugs targeting macrophages in atherosclerotic plaques

Alaarg, A. M. S. A., Zheng, K. H., van der Valk, F. M., Eduardo Da Silva, A., Versloot, M., Quarles van Ufford, L. C., Schulte, D. M., Storm, G., Metselaar, J. M., Stroes, E. S. & Hamers, A. A. J., 2016, In : Vascular pharmacology. 82, p. 51-59

Research output: Contribution to journalArticleAcademicpeer-review

27 Citations (Scopus)
59 Downloads (Pure)

Nanoparticles for intravascular applications: physicochemical characterization and cytotoxicity testing

Matuszak, J., Baumgartner, J., Zaloga, J., Juenet, M., Da Silva, A. E., Franke, D., Almer, G., Texier, I., Faivre, D., Metselaar, J. M., Navarro, F. P., Chauvierre, C., Prassl, R., Dézsi, L., Urbanics, R., Alexiou, C., Mangge, H., Szebeni, J., Letourneur, D. & Cicha, I., 2016, In : Nanomedicine. 11, 6, p. 597-616

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Cytotoxicity
Nanoparticles
Nanosystems
Testing
Endothelial cells
24 Citations (Scopus)
51 Downloads (Pure)

New low-flux mixed matrix membranes that offer superior removal of protein-bound toxins from human plasma

Pavlenko, D., Geffen, E., van Steenbergen, M. J., Glorieux, G., Vanholder, R., Gerritsen, K. G. F. & Stamatialis, D., 2016, In : Scientific reports. 6, 34429.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Dialysis
Membranes
Renal Dialysis
Indican
Proteins
2 Downloads (Pure)

New Working Group 'Bioartificial Organs'

Stamatialis, D., 1 Jun 2016, In : EASO Newsletter. 2016, June, p. 3

Research output: Contribution to journalArticlePopular

Open Access
File
Biomedical Technology Assessment
Health
Technology
Pharmaceutical Preparations
Decision Support Techniques
40 Citations (Scopus)
51 Downloads (Pure)

Pharmacological intervention in hepatic stellate cell activation and hepatic fibrosis

Schon, H-T., Bartneck, M., Borkham-Kamphorst, E., Nattermann, J., Lammers, T. G. G. M., Tacke, F. & Weiskirchen, R., 2016, In : Frontiers in pharmacology. 7, 33, p. - 22 p., 33.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
5 Citations (Scopus)

Poly(Amido Amine)s containing agmatine and butanol side chains as efficient gene carriers

Won, Y-W., Ankone, M. J. K., Engbersen, J. F. J., Feijen, J. & Kim, S. W., 11 Dec 2016, In : Macromolecular bioscience. 16, 4, p. 619-626

Research output: Contribution to journalArticleAcademicpeer-review

Agmatine
Butanols
Butenes
Amines
Cystamine
3 Citations (Scopus)
66 Downloads (Pure)

Polymeric Nanogels with Tailorable Degradation Behavior

Chen, Y., van Steenbergen, M. J., Li, D., van de Dikkenberg, J. B., Lammers, T. G. G. M., van Nostrum, C. F., Metselaar, J. M. & Hennink, W. E., 2016, In : Macromolecular bioscience. 16, 8, p. 1122-1137

Research output: Contribution to journalArticleAcademicpeer-review

File
Degradation
Esters
Drug delivery
glycolic acid
Carbonates
14 Citations (Scopus)
1 Downloads (Pure)

Polymer-polymer composites for the design of strong and tough degradable biomaterials

Zhang, X., Geven, M. A., Grijpma, D. W., Gautrot, J. & Peijs, T., 2016, In : Materials today communications. 8, p. 53-63

Research output: Contribution to journalArticleAcademicpeer-review

Biocompatible Materials
Biomaterials
Polymers
Fibers
Composite materials
12 Citations (Scopus)
41 Downloads (Pure)

Preclinical detection of liver fibrosis using dual-modality photoacoustic/ultrasound system

van den Berg, P. J., Bansal, R., Daoudi, K., Steenbergen, W. & Prakash, J., 2016, In : Biomedical optics express. 7, 12, p. 5081-5091

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
fibrosis
liver
Liver Cirrhosis
Liver
angiogenesis
4 Citations (Scopus)
1 Downloads (Pure)
Graphite
Oxides
Graphene
Carbonates
Composite materials
12 Citations (Scopus)

Preparation of Designed Poly(trimethylene carbonate) Meniscus Implants by Stereolithography: Challenges in Stereolithography

van Bochove, B., Hannink, G., Buma, P. & Grijpma, D. W., 2016, In : Macromolecular bioscience. 16, 12, p. 1853-1863

Research output: Contribution to journalArticleAcademicpeer-review

Stereolithography
Carbonates
Resins
Coloring Agents
Methacrylates
41 Citations (Scopus)

Quantitative micro-computed tomography imaging of vascular dysfunction in progressive kidney diseases

Ehling, J., Babickova, J., Gremse, F., Klinkhammer, B. M., Baetke, S., Knuechel, R., Kiessling, F., Floege, J., Lammers, T. & Boor, P., 2016, In : Journal of the American Society of Nephrology. 27, 2, p. 520-532

Research output: Contribution to journalArticleAcademicpeer-review

Kidney Diseases
Blood Vessels
Tomography
Kidney
Fibrosis
10 Citations (Scopus)
174 Downloads (Pure)

Radionuclide imaging of liposomal drug delivery

van der Geest, T., Laverman, P., Metselaar, J. M., Storm, G. & Boerman, O. C., 2016, In : Expert opinion on drug delivery. 13, 9, p. 1231-1242

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Liposomes
Radionuclide Imaging
Pharmaceutical Preparations
Drug Monitoring
Expert Testimony
25 Citations (Scopus)
74 Downloads (Pure)

Regeneration of the lung: Lung stem cells and the development of lung mimicking devices

Schilders, K., Eenjes, E., van Riet, S., Poot, A. A., Stamatialis, D., Truckenmüller, R. K., Hiemstra, P. & Rottier, R., 2016, In : Respiratory research. 17, 44, p. -

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Regeneration
Stem Cells
Equipment and Supplies
Lung
Lung Volume Measurements
44 Citations (Scopus)

Sonoporation enhances liposome accumulation and penetration in tumors with low EPR

Theek, B., Baues, M., Ojha, T., Möckel, D., Veettil, S. K., Steitz, J., van Bloois, L., Storm, G., Kiessling, F. & Lammers, T. G. G. M., 2016, In : Journal of controlled release. 231, p. 77-85

Research output: Contribution to journalArticleAcademicpeer-review

Liposomes
Permeability
Microbubbles
Neoplasms
Drug Delivery Systems
18 Citations (Scopus)
42 Downloads (Pure)

Squamous Cell Carcinoma Xenografts: Use of VEGFR2-targeted Microbubbles for Combined Functional and Molecular US to Monitor Antiangiogenic Therapy Effects

Baetke, S. C., Rix, A., Tranquart, F., Schneider, R., Lammers, T., Kiessling, F. & Lederle, W., 2016, In : Radiology. 278, 2, p. 430-440

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Microbubbles
Vascular Endothelial Growth Factor Receptor-2
Heterografts
Squamous Cell Carcinoma
Ultrasonography
84 Citations (Scopus)

Strategies for encapsulation of small hydrophilic and amphiphilic drugs in PLGA microspheres: State-of-the-art and challenges

Ramazani, F., Chen, W., van Nostrum, C. F., Storm, G., Kiessling, F., Lammers, T. G. G. M., Hennink, W. E. & Kok, R. J., 2016, In : International journal of pharmaceutics. 499, 1-2, p. 358-367

Research output: Contribution to journalArticleAcademicpeer-review

Microspheres
Drug Compounding
Oils
Water
Pharmaceutical Preparations
8 Citations (Scopus)

Submicron-surface structured tricalcium phosphate ceramic enhances the bone regeneration in canine spine environment

Duan, R., Barbieri, D., Luo, X., Weng, J., de Bruijn, J. D. & Yuan, H., 2016, In : Journal of orthopaedic research. 34, 11, p. 1865-1873

Research output: Contribution to journalArticleAcademicpeer-review

Bone Regeneration
Canidae
Spine
Osteogenesis
Bone and Bones
9 Citations (Scopus)

Surfactant-free Preparation of Highly Stable Zwitterionic Poly(amido amine) Nanogels with Minimal Cytotoxicity

Ekkelenkamp, A. E., Jansman, M. M. T., Roelofs-Haarhuis, H. M., Engbersen, J. F. J. & Paulusse, J. M. J., 2016, In : Acta biomaterialia. 30, p. 126-134

Research output: Contribution to journalArticleAcademicpeer-review

Cytotoxicity
Surface charge
Surface-Active Agents
Amines
Surface active agents
11 Citations (Scopus)
1 Downloads (Pure)
Hydrogels
Cell adhesion
Polyethylene glycols
Hydrogel
Cell proliferation
13 Citations (Scopus)

Tailoring the physicochemical properties of core-crosslinked polymeric micelles for pharmaceutical applications

Hu, Q., Rijcken, C. J. F., Gaal, E., Brundel, P., Kostkova, H., Etrych, T., Weber, B., Barz, M., Kiessling, F., Prakash, J., Storm, G., Hennink, W. E. & Lammers, T. G. G. M., 2016, In : Journal of controlled release. 244, part B, p. 314-325

Research output: Contribution to journalArticleAcademicpeer-review

Micelles
docetaxel
Pharmaceutical Preparations
Nanomedicine
Clinical Trials, Phase I
3 Citations (Scopus)

Targeting cellular and microenvironmental multidrug resistance

Tezcan, O., Ojha, T., Storm, G., Kiessling, F. & Lammers, T. G. G. M., 2016, In : Expert opinion on drug delivery. 13, 9, p. 1199-1202

Research output: Contribution to journalArticleAcademicpeer-review

17 Citations (Scopus)
54 Downloads (Pure)

The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance

Gautheron, J., Vucur, M., Schneider, A. T., Severi, I., Lammers, T. G. G. M., Heikenwalder, LM. & Luedde, T., 2016, In : Nature communications. 7, 11869, p. 11869- 11869.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Receptor-Interacting Protein Serine-Threonine Kinases
adipose tissues
White Adipose Tissue
Glucose Intolerance
glucose
25 Citations (Scopus)
16 Downloads (Pure)

Tissue adhesives for meniscus tear repair: an overview of current advances and prospects for future clinical solutions

Bochyńska, A. I., Hannink, G., Grijpma, D. W. & Buma, P., 2016, In : Journal of materials science. Materials in medicine. 27, 5, 85.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Tissue Adhesives
Tears
Adhesives
Repair
Tissue
8 Citations (Scopus)
1 Downloads (Pure)

Tough biodegradable mixed-macromer networks and hydrogels by photo-crosslinking in solution

Zant, E. & Grijpma, D. W., 2016, In : Acta biomaterialia. 31, p. 80-88

Research output: Contribution to journalArticleAcademicpeer-review

Hydrogels
Ethylene Glycol
Crosslinking
Polyethylene glycols
Carbonates
30 Citations (Scopus)
1 Downloads (Pure)

Tumor stroma-containing 3D spheroid arrays: A tool to study nanoparticle penetration

Priwitaningrum, D. L., Priwitaningrum, D. L., Blondé, J-B. G. M., Blonde, J-B. G., Sridhar, A., van Baarlen, J., Hennink, W. E., Storm, G., le Gac, S. & Prakash, J., 2016, In : Journal of controlled release. 244, part B, p. 257-268

Research output: Contribution to journalArticleAcademicpeer-review

Nanoparticles
Neoplasms
Silicon Dioxide
Fibroblasts
3T3 Cells
37 Citations (Scopus)

Ultrasound-mediated drug delivery to the brain: principles, progress and prospects

Dasgupta, I., Liu, M., Ojha, T., Storm, G., Kiessling, F. & Lammers, T. G. G. M., 2016, In : Drug discovery today. 20, p. 41-48

Research output: Contribution to journalArticleAcademicpeer-review

Microbubbles
Nanomedicine
Brain
Neurodegenerative Diseases
Pharmaceutical Preparations
22 Citations (Scopus)
3 Downloads (Pure)

Upscaling of a living membrane for bioartificial kidney device

Chevtchik, N., Fedecostante, M., Jansen, J., Mihajlovic, M., Wilmer, M., Rüth, M., Masereeuw, R. & Stamatialis, D., 2016, In : European journal of pharmacology. 790, p. 28-35

Research output: Contribution to journalArticleAcademicpeer-review

Kidney
Equipment and Supplies
Membranes
Waste Products
Epithelial Cells
22 Citations (Scopus)
134 Downloads (Pure)

UV cross-linkable graphene/poly(trimethylene carbonate) composites for 3D printing of electrically conductive scaffolds

Sayyar, S., Bjorninen, M., Haimi, S., Miettinen, S., Gilmore, K., Grijpma, D. W. & Wallace, G., 2016, In : ACS applied materials & interfaces. 8, 46, p. 31916-31925

Research output: Contribution to journalArticleAcademicpeer-review

File
Graphite
Stem cells
Scaffolds
Graphene
Printing
2015
15 Citations (Scopus)

[18]F FDG PET/CT imaging to monitor the therapeutic effect of liposome-encapsulated prednisolone in experimental rheumatoid arthritis

van der Geest, T., Metselaar, J. M., Gerrits, D., van Lent, P. L., Storm, G., Laverman, P. & Boerman, O. C., 2015, In : Journal of controlled release. 209, p. 20-26

Research output: Contribution to journalArticleAcademicpeer-review

Experimental Arthritis
Therapeutic Uses
Prednisolone
Liposomes
Arthritis
17 Citations (Scopus)

A Biodegradable Glue for Annulus Closure: Evaluation of Strength and Endurance

Vergroesen, P. P. A., Bochynska, A., Emanuel, K. S., Sharifi, S., Kingma, I., Grijpma, D. W. & Smit, T. H., 2015, In : Spine. 40, 9, p. 622-628

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)
2 Downloads (Pure)

A Combinatorial Photocrosslinking Method for the Preparation of Porous Structures with Widely Differing Properties

Zant, E., Blokzijl, M. & Grijpma, D. W., 2015, In : Macromolecular rapid communications. 36, 21, p. 1902-1909

Research output: Contribution to journalArticleAcademicpeer-review

41 Citations (Scopus)

A combined biomaterial and cellular approach for annulus fibrosus rupture repair

Pirvu, T., Blanquer, S., Benneker, L., Grijpma, D. W., Richards, R., Alini, M., Eglin, D., Grad, S. & Li, Z., 2015, In : Biomaterials. 42, 1, p. 11-19

Research output: Contribution to journalArticleAcademicpeer-review

Biocompatible Materials
Biomaterials
Rupture
Gene Expression Regulation
Repair
9 Citations (Scopus)

A field cancellation signal extraction method for magnetic particle imaging

Schulz, V., Straub, M., Mahlke, M., Hubertus, S., Lammers, T. G. G. M. & Kiessling, F., 2015, In : IEEE transactions on magnetics. 51, 2, p. 6501804- 6501804.

Research output: Contribution to journalArticleAcademicpeer-review

13 Citations (Scopus)

Alginate microgels loaded with temperature sensitive liposomes for magnetic resonance imageable drug release and microgel visualization

van Elk, M., Lorenzato, C., Ozbakir, B., Oerlemans, C., Storm, G., Nijsen, F., Deckers, R., Vermonden, T. & Hennink, W. E., 2015, In : European polymer journal. 72, p. 620-631

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)
53 Downloads (Pure)

Alginate microspheres containing temperature sensitive liposomes (TSL) for MR-guided embolization and triggered release of doxorubicin

van Elk, M., Ozbakir, B., Barten-Rijbroek, A. D., Storm, G., Nijsen, F., Hennink, W. E., Vermonden, T. & Deckers, R., 2015, In : PLoS ONE. 10, 11, p. e0141626- e141626.

Research output: Contribution to journalArticleAcademicpeer-review

File
doxorubicin
alginates
Microspheres
Liposomes
Doxorubicin