Biomaterials Science and Technology

Research Output 1970 2019

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2015
5 Citations (Scopus)
35 Downloads (Pure)

Multilayered Thin Films from Boronic Acid-Functional Poly(amido amine)s

Hujaya, S. D., Engbersen, J. F. J. & Paulusse, J. M. J., 2015, In : Pharmaceutical research. 32, 9, p. 3066-3086

Research output: Contribution to journalArticleAcademicpeer-review

File
Boronic Acids
Amines
Chondroitin Sulfates
COS Cells
Multilayers
1 Citation (Scopus)
25 Downloads (Pure)

Multilayered Thin Films from Boronic Acid-Functional Poly(amido amine)s as Drug-Releasing Surfaces

Hujaya, S. D., Engbersen, J. F. J. & Paulusse, J. M. J., 2015, In : Pharmaceutical research. 32, 11, p. 3732-3745

Research output: Contribution to journalArticleAcademicpeer-review

File
Boronic Acids
Amines
Thin films
Pharmaceutical Preparations
Multilayers
5 Citations (Scopus)

Multilayered Thin Films from Poly(amido amine)s and DNA

Hujaya, S. D., Engbersen, J. F. J. & Paulusse, J. M. J., 2015, In : Acta biomaterialia. 22, p. 19-31

Research output: Contribution to journalArticleAcademicpeer-review

Amines
DNA
Thin films
Multilayers
Transfection
164 Citations (Scopus)

Noninvasive imaging of nanomedicines and nanotheranostics: principles, progress, and prospects

Kunjachan, S., Ehling, J., Storm, G., Kiessling, F. & Lammers, T., 2015, In : Chemical reviews. 115, 19, p. 10907-10937

Research output: Contribution to journalArticleAcademicpeer-review

17 Citations (Scopus)

Noninvasive molecular ultrasound monitoring of vessel healing after intravascular surgical procedures in a preclinical setup

Curaj, A., Wu, Z., Fokong, S., Liehn, E., Weber, C., Burlacu, A., Lammers, T. G. G. M., van Zandvoort, M. & Kiessling, F., 2015, In : Arteriosclerosis, thrombosis and vascular biology. 35, 6, p. 1366-1373

Research output: Contribution to journalArticleAcademicpeer-review

28 Downloads (Pure)

Onderzoek naar long-op-een-chip

Poot, A. A., 2015, In : Papillon. 11, 1 (febr 2015), p. 8-

Research output: Contribution to journalArticlePopular

File
Interviews
21 Citations (Scopus)

Pharmaceutical development and preclinical evaluation of a GMP-grade anti-inflammatory nanotherapy

Lobatto, M. E., Calcagno, C., Otten, M. J., Millon, A., Ramachandran, S., Paridaans, M. P. M., van der Valk, F. M., Storm, G., Stroes, E. S. G., Fayad, Z. A., Mulder, W. J. M. & Metselaar, J. M., 2015, In : Nanomedicine. 11, 5, p. 1133-1140

Research output: Contribution to journalArticleAcademicpeer-review

Drug products
Phosphates
Anti-Inflammatory Agents
Multimodal Imaging
Pharmaceutical Preparations
5 Citations (Scopus)

Poly(amido amine)-based multilayered thin films on 2D and 3D supports for surface-mediated cell transfection

Hujaya, S. D., Marchioli, G., Roelofs-Haarhuis, H. M., van Apeldoorn, A. A., Moroni, L., Karperien, H. B. J., Paulusse, J. M. J. & Engbersen, J. F. J., 28 Jan 2015, In : Journal of controlled release. 205, p. 181-189 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Amines
Transfection
Cell Adhesion
Heparin
Cystamine
51 Citations (Scopus)

Prednisolone-containing liposomes accumulate in human atherosclerotic macrophages upon intravenous administration

van der Valk, F. M., Storm, G., van Wijk, D. F., Lobatto, M. E., Metselaar, J. M., Verberne, H. J., Willems, M. C. M., Legemate, D. A., Nederveen, A. J., Calcagno, C., Mani, V., Ramachandran, S., Paridaans, M. P. M., Otten, M. J., Dallinga-Thie, G. M., Fayad, Z. A., Nieuwdorp, M., Schulte, D. M., Mulder, W. J. M. & Stroes, E. S. G., 2015, In : Nanomedicine. 11, 5, p. 1039-1046

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Preparation and mechanical properties of photo-crosslinked poly(trimethylene carbonate) and nano-hydroxyapatite composites

Geven, M. A., Barbieri, D., Yuan, H., de Bruijn, J. D. & Grijpma, D. W., 27 Mar 2015, In : Clinical hemorheology and microcirculation. 60, 1, p. 3-11

Research output: Contribution to journalArticleAcademicpeer-review

Durapatite
Orbital Implants
Apatites
Tensile Strength
Tears
2 Citations (Scopus)

Preparation of gentamicin dioctyl sulfosuccinate loaded poly(trimethylene carbonate) matrices intended for the treatment of orthopaedic infections

ter Boo, G. A., Grijpma, D. W., Richards, R. G., Moriarty, T. F. & Eglin, D., 2015, In : Clinical hemorheology and microcirculation. 60, 1, p. 89-98

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Prospects and progress of DNA vaccines for treating hepatitis B

Chen, M., Jagya, N., Bansal, R., Frelin, L. & Sällberg, M., 12 Dec 2015, In : Expert review of vaccines. 15, 5, p. 629-640

Research output: Contribution to journalArticleAcademicpeer-review

DNA Vaccines
Hepatitis B
Hepatitis B virus
Chronic Hepatitis B
Therapeutics
15 Citations (Scopus)

Reductively degradable α-amino acid-based poly(ester amide)-graft-galactose copolymers: facile synthesis, self-assembly, and hepatoma-targeting doxorubicin delivery

Lv, J., Sun, H., Zou, Y., Meng, F., Dias, A. A., Hendriks, M., Feijen, J. & Zhong, Z., 2015, In : Biomaterials. 3, 7, p. 1134-1146

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)

Role of platelet-derived growth factor-CC in capillary rarefaction in renal fibrosis

Boor, P., Babickova, J., Steegh, F., Hautvast, P., Martin, I. V., Djudjaj, S., Nakagawa, T., Ehling, J., Gremse, F., Bücher, E., Eriksson, U., van Roeyen, C. R. C., Eitner, F., Lammers, T., Floege, J., Peutz-Kootstra, C. J. & Ostendorf, T., 2015, In : American journal of pathology. 185, 8, p. 2132-2142

Research output: Contribution to journalArticleAcademicpeer-review

Platelet-Derived Growth Factor
Fibrosis
Kidney
Platelet-Derived Growth Factor Receptors
Ureteral Obstruction
29 Citations (Scopus)

Selective delivery of IFN-γ to renal interstitial myofibroblasts: a novel strategy for the treatment of renal fibrosis

Poosti, F., Bansal, R., Yazdani, S., Prakash, J., Post, E., Klok, P., van den Born, J., de Borst, M. H., van Goor, H., Poelstra, K. & Hillebrands, J-L., 2 Dec 2015, In : FASEB journal. 29, 3, p. 1029-1042

Research output: Contribution to journalArticleAcademicpeer-review

Myofibroblasts
Platelet-Derived Growth Factor Receptors
Fibrosis
Kidney
Ureteral Obstruction
15 Citations (Scopus)

SIRT1 inhibition in pancreatic cancer models: contrasing effects in vitro and in vivo

Oon, C. E., Strell, C., Yeong, K. Y., Östman, A. & Prakash, J., 2015, In : European journal of pharmacology. 757, p. 59-67

Research output: Contribution to journalArticleAcademicpeer-review

37 Citations (Scopus)
22 Downloads (Pure)

Sonochemotherapy: From bench to bedside

Lammertink, B. H. A., Bos, C., Deckers, R., Storm, G., Moonen, C. T. W. & Escoffre, J-M., 2015, In : Frontiers in pharmacology. 6, JUN, 138.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Microbubbles
Pharmaceutical Preparations
Blood Vessels
Permeability
Appointments and Schedules
8 Citations (Scopus)
39 Downloads (Pure)

Stromal targets for fluorescent-guided oncologic surgery

Boonstra, M. C., Prakash, J., van de Velde, C. J. H., Mesker, W. E., Kuppen, P. J. K., Vahrmeijer, A. L. & Sier, C. F. M., 2015, In : Frontiers in oncology. 5, 254, p. - 8 p., 254.

Research output: Contribution to journalArticleAcademicpeer-review

File
Computer-Assisted Surgery
Neoplasms
Peptides
Antibodies
Stromal Cells
11 Citations (Scopus)

Strontium-Containing Apatite/Poly Lactide Composites Favoring Osteogenic Differentiation and in Vivo Bone Formation

Luo, X., Barbieri, D., Zhang, Y., Yan, Y., de Bruijn, J. D. & Yuan, H., 2015, In : ACS biomaterials science & engineering. 1, 2, p. 85-93

Research output: Contribution to journalArticleAcademic

Apatites
Strontium
Apatite
Bone
Composite materials
1 Downloads (Pure)
Open Access
File
Liver Cirrhosis
Liver Diseases
Liver
Research
21 Citations (Scopus)

Sunitinib microspheres based on [PDLLA-PEG-PDLLA]-b-PLLA multi-block copolymers for ocular drug delivery

Ramazani, F., Hiemstra, C., Steendam, R., Kazazi-Hyseni, F., van Nostrum, C. F., Storm, G., Kiessling, F., Lammers, T. G. G. M., Hennink, W. E. & Kok, R. J., 2015, In : European journal of pharmaceutics and biopharmaceutics. 95, Part B, p. 368-377

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)

Superoxide dismutase enzymosomes: carrier capacity optimization, in vivo behaviour and therapeutic activity

Corvo, M. L., Marinho, H. S., Marcelino, P., Lopes, R. M., Vale, C. A., Marques, C. R., Martins, L. C. D., Laverman, P., Storm, G. & Martins, M. B., 2015, In : Pharmaceutical research. 32, 1, p. 91-102

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)

Synthesis and characterization of image-able polyvinyl alcohol microspheres for image-guided chemoembolization

Negussie, A. H., Dreher, M. R., Johnson, C. G., Tang, Y., Lewis, A. L., Storm, G., Sharma, K. V. & Wood, B. J., 2015, In : Journal of materials science. Materials in medicine. 26, 6, 198.

Research output: Contribution to journalArticleAcademicpeer-review

Polyvinyl Alcohol
Polyvinyl alcohols
Microspheres
Tumors
Drug therapy

Targeted liposomal drug delivery to inhibit atherosclerotic plaque inflammation

Alaarg, A. M. S. A., Hamers, A. A. J., Versloot, M., Lobatto, M. E., Mulder, W. J. M., Stroes, E. S. G., Storm, G. & Metselaar, J. M., 22 Mar 2015, In : Atherosclerosis. 241, 1, p. e87- EAS-0672.

Research output: Contribution to journalArticleAcademicpeer-review

18 Citations (Scopus)
40 Downloads (Pure)

The crosstalk between osteoclasts and osteoblasts is dependent upon the composition and structure of biphasic calcium phosphates

Shiwaku, Y., Neff, L., Nagano, K., Takeyama, K., de Bruijn, J. D., Dard, M., Gori, F. & Baron, R., 2015, In : PLoS ONE. 10, 7, p. - 17 p., e0132903.

Research output: Contribution to journalArticleAcademicpeer-review

File
osteoclasts
calcium phosphates
osteoblasts
Osteoblasts
Osteoclasts
31 Citations (Scopus)
16 Downloads (Pure)

The foreign body giant cell cannot resorb bone, but dissolves hydroxyapatite like osteoclasts

Harkel, B. T., Schoenmaker, T., Picavet, D. I., Davison, N. L., De Vries, T. J. & Everts, V., 1 Oct 2015, In : PLoS ONE. 10, 10, e0139564.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Foreign Body Giant Cells
hydroxyapatite
osteoclasts
foreign bodies
giant cells
25 Citations (Scopus)
80 Downloads (Pure)

The interplay of the Notch signaling in hepatic stellate cells and macrophages determines the fate of liver fibrogenesis

Bansal, R., van Baarlen, J., Storm, G. & Prakash, J., 2015, In : Scientific reports. 5, 18272, 18272.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Hepatic Stellate Cells
Macrophages
Liver
Liver Cirrhosis
Fibroblasts
23 Downloads (Pure)

The next generation nanotechnology based drug delivery

Engbersen, J. F. J., Di Biase, D., Saini, S. & Walsh, S. T., 2015, In : CMM international. 7, 5, p. -

Research output: Contribution to journalArticleAcademic

File
62 Citations (Scopus)

Theranastic USPIO-loaded microbubbles for mediating and monitoring blood-brain barrier permeation

Lammers, T. G. G. M., Koczera, P., Fokong, S., Gremse, F., Ehling, J., Vogt, M., Pich, A., Storm, G., van Zandvoort, M. & Kiessling, F., 2015, In : Advanced functional materials. 25, 1, p. 36-43

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)
50 Downloads (Pure)

The RAPIDOS project – European and Chinese collaborative research on biomaterials

Eglin, D., Alini, M., de Bruijn, J. D., Gautrot, J., Grijpma, D. W., Kamer, L., Lai, Y., Lu, S., Peijs, T., Peng, J., Tang, T. T., Wang, X., Richards, R. G. & Qin, L., 2015, In : Journal of orthopaedic translation. 3, 2, p. 78-84

Research output: Contribution to journalArticleAcademicpeer-review

File
Biocompatible Materials
Bone and Bones
Technology
Research
China
26 Citations (Scopus)

Treatment of the degenerated intervertebral disc; closure, repair and regeneration of the annulus fibrosus

Sharifi, S., Bulstra, S. K., Grijpma, D. W. & Kuijer, R., 25 Feb 2015, In : Journal of tissue engineering and regenerative medicine. 9, 10, p. 1120-1132

Research output: Contribution to journalArticleAcademicpeer-review

Intervertebral Disc
Intervertebral Disc Degeneration
Regeneration
Repair
Low Back Pain
34 Citations (Scopus)

USPIO-labeled textile materials for non-invasive MR imaging of tissue-engineered vascular grafts

Mertens, M. E., Koch, S., Lammers, T. G. G. M., Schuster, P., Wehner, J., Wu, Z., Gremse, F., Schulz, V., Rongen, L., Wolf, F., Frese, J., Gesche, V. N., van Zandvoort, M., Mela, P., Jockenhoeve, S. & Kiessling, F., 2015, In : Biomaterials. 39, p. 155-163

Research output: Contribution to journalArticleAcademicpeer-review

28 Citations (Scopus)

Water-soluble dopamine-based polymers for photoacoustic imaging

Repenko, T., Fokong, S., De Laporte, L., Go, D., Kiessling, F., Lammers, T. G. G. M. & Kuehne, A., 2015, In : Chemical communications. 51, 28, p. 6084-6087

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)
58 Downloads (Pure)

μCT based assessment of mechanical deformation of designed PTMC scaffolds

Narra, N., Blanquer, S., Haimi, S., Grijpma, D. W. & Hyttinen, J., 2015, In : Clinical hemorheology and microcirculation. 60, 1, p. 99-108

Research output: Contribution to journalArticleAcademicpeer-review

File
2014
5 Citations (Scopus)
19 Downloads (Pure)

Absolute MR thermometry using nanocarriers

Deckers, R., Sprinkhuizen, S. M., Crielaard, B. J., Ippel, J. H., Boelens, R., Bakker, C. J. G., Storm, G., Lammers, T. G. G. M. & Bartels, L. W., 2014, In : Contrast media & molecular imaging. 9, 4, p. 283-290

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
31 Citations (Scopus)
40 Downloads (Pure)

Absorption reconstruction improves biodistribution assessment of fluorescent nanoprobes using hybrid Fluorescence-mediated tomography

Gremse, F., Theek, B., Kunjachan, S., Lederle, W., Pardo, A., Barth, S., Lammers, T. G. G. M., Naumann, U. & Kiessling, F., 2014, In : Theranostics. 4, 10, p. 960-971

Research output: Contribution to journalArticleAcademicpeer-review

File
90 Citations (Scopus)

Advanced drug and gene delivery systems based on functional biodegradable polycarbonates and copolymers

Chen, W., Meng, F., Cheng, R., Deng, C., Feijen, J. & Zhong, Z., 2014, In : Journal of controlled release. 190, p. 398-414

Research output: Contribution to journalArticleAcademicpeer-review

28 Citations (Scopus)

Biodegradable elastomers for biomedical applications and regenerative medicine

Bat, E., Zhang, Z., Feijen, J., Grijpma, D. W. & Poot, A. A., 2014, In : Regenerative medicine. 9, 3, p. 385-398

Research output: Contribution to journalArticleAcademicpeer-review

Elastomers
Biodegradable polymers
Regenerative Medicine
Polymers
Degradation
50 Citations (Scopus)

Biomaterials in search of a meniscus substitute

Rongen, J. J., van Tienen, T. G., van Bochove, B., Grijpma, D. W. & Buma, P., 2014, In : Biomaterials. 35, 11, p. 3527-3540

Research output: Contribution to journalArticleAcademicpeer-review

Biocompatible Materials
Biomaterials
Osteoarthritis
Materials properties
Knee Joint

Bioreactor - Nieren in een buisje

Stamatialis, D., 12 Nov 2014, In : Twentsche Courant Tubantia. 12-11-2014, p. 16

Research output: Contribution to journalArticlePopular

103 Citations (Scopus)

CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis

Ehling, J., Bartneck, M., Wei, X., Gremse, F., Fech, V., Möckel, D., Baeck, C., Hittatiya, K., Eulberg, D., Luedde, T., Kiessling, F., Trautwein, C., Lammers, T. G. G. M. & Tacke, F., 2014, In : Gut. 63, 12, p. 1960-1971

Research output: Contribution to journalArticleAcademicpeer-review

45 Citations (Scopus)

Characterizing EPR-mediated passive drug targeting using contrast-enhanced functional ultrasound imaging

Theek, B., Gremse, F., Kunjachan, S., Fokong, S., Pola, R., Pechar, M., Deckers, R., Storm, G., Ehling, J., Kiessling, F. & Lammers, T., 2014, In : Journal of controlled release. 182, p. 83-89 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Drug Delivery Systems
Permeability
Ultrasonography
Tomography
Neoplasms
1 Citation (Scopus)

Controlled culture of adherent cells in a novel, closed bioreactor system for cell therapy production

Das, R., Roosloot, R., Tra, W., Roelofs, H., van Santen, P. & de Bruijn, J. D., 2014, In : Cytotherapy. 16, 4, suppl., p. S102-S103

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Controlling surface microstructure of calcium phosphate ceramic from random to custom-design

Wang, L., Luo, X., Barbieri, D., Bao, C. & Yuan, H., 2014, In : Ceramics international. 40, 6, p. 7889-7897

Research output: Contribution to journalArticleAcademicpeer-review

Calcium phosphate
Microstructure
Bone
Hydroxyapatite
Apatite
26 Citations (Scopus)

Decationized polyplexes as stable and safe carrier systems for improved biodistribution in systemic gene therapy

Novo, L., Rizzo, L. Y., Golombek, S. K., Dakwar, G. R., Lou, B., Remaut, K., Mastrobattista, E., van Nostrum, C. F., Jahnen-Dechent, W., Kiessling, F., Braeckmans, K., Lammers, T. G. G. M. & Hennink, W. E., 2014, In : Journal of controlled release. 195, p. 162-175

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Development of multilayer constructs for tissue engineering

Bettahalli Narasimha, M. S., Groen, N., Steg, H., Unadkat, H. V., de Boer, J., van Blitterswijk, C., Wessling, M. & Stamatialis, D., 12 Apr 2014, In : Journal of tissue engineering and regenerative medicine. 8, 2, p. 106-119

Research output: Contribution to journalArticleAcademicpeer-review

Tissue Engineering
Tissue engineering
Multilayers
Tissue
Nutrients
3 Citations (Scopus)

Effect of tissue scaffold topography on protein structure monitored by fluorescence spectroscopy

Portugal, C. A. M., Truckenmüller, R. K., Stamatialis, D. & Crespo, J. G., 2014, In : Journal of biotechnology. 189, p. 166-174

Research output: Contribution to journalArticleAcademicpeer-review

Tissue Scaffolds
Fluorescence Spectrometry
Fluorescence spectroscopy
Topography
Proteins
4 Citations (Scopus)

Facile method of building hydroxyapatite 3D scaffolds assembled from porous hollow fibers enabling nutrient delivery

Salamon, D., Da Silva Teixeira, S., Dutczak, S. M. & Stamatialis, D., 2014, In : Ceramics international. 40, 9, Part B, p. 14793-14799

Research output: Contribution to journalArticleAcademicpeer-review

Scaffolds (biology)
Hydroxyapatite
Nutrients
Scaffolds
Fibers
38 Citations (Scopus)

Features of complement activation-related pseudoallergy to liposomes with different surface charge and PEGylation: Comparison of the porcine and rat responses

Dézsi, L., Fülöp, T., Mészàros, T., Szénåsi, G., Urbanics, R., Våzsonyi, C., Orfi, E., Rosivall, L., Nemes, R., Kok, R. J., Metselaar, J. M., Storm, G. & Szebeni, J., 2014, In : Journal of controlled release. 195, p. 2-10

Research output: Contribution to journalArticleAcademicpeer-review

65 Citations (Scopus)

Glyco-nanoparticles with sheddable saccharide shells: A unique and potent platform for hepatoma-targeting delivery of anticancer drugs

Chen, W., Zou, Y., Meng, F., Cheng, R., Deng, C., Feijen, J. & Zhong, Z., 2014, In : Biomacromolecules. 15, 3, p. 900-907

Research output: Contribution to journalArticleAcademicpeer-review