Biomaterials Science and Technology

Research Output 1970 2019

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In Vitro Evaluation of Small Molecule Delivery into Articular Cartilage: Effect of Synovial Clearance and Compressive Load

Spitters, T. W. G. M., Stamatialis, D., Petit, A., De Leeuw, M. G. W. & Karperien, M., 6 Jun 2019, In : Assay and Drug Development Technologies. 17, 4, p. 191-200 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Articular Cartilage
Bromphenol Blue
Pharmaceutical Preparations
Synovial Fluid
Bioreactors
61 Citations (Scopus)

In vitro in vivo protein delivery from in situ forming poly(ethylene glycol)-poly(lactide) hydrogels

Hiemstra, C., Zhong, Z., van Tomme, S. R., van Steenbergen, M. J., Jacobs, J. J. L., den Otter, W., Hennink, W. E. & Feijen, J., 2007, In : Journal of controlled release. 119, 3, p. 320-327

Research output: Contribution to journalArticleAcademicpeer-review

44 Citations (Scopus)
54 Downloads (Pure)

In vitro leucocyte adhesion to modified polyurethane surfaces: I. Effect of ionizable functional groups

Bruil, A., Terlingen, J. G. A., Beugeling, T., van Aken, W. G. & Feijen, J., 1992, In : Biomaterials. 13, 13, p. 915-923 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Polyurethanes
Functional groups
Leukocytes
Adhesion
Carboxylic Acids
29 Citations (Scopus)
27 Downloads (Pure)

In vitro leukocyte adhesion to modified polyurethane surfaces: II. Effect of wettability

Bruil, A., Brenneisen, L. M., Terlingen, J. G. A., Beugeling, T., van Aken, W. G. & Feijen, J., 1994, In : Journal of colloid and interface science. 1994, 165, p. 72-81

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Polyurethanes
Wetting
Adhesion
Lymphocytes
Argon
95 Citations (Scopus)
83 Downloads (Pure)

In vivo and in vitro degradation of glycine/DL-lactic acid copolymers

Schakenraad, J. M., Nieuwenhuis, P., Molenaar, I., Helder, J., Dijkstra, P. J. & Feijen, J., 1989, In : Journal of biomedical materials research. 23, 11, p. 1271-1288

Research output: Contribution to journalArticleAcademic

File
60 Citations (Scopus)

In vivo and in vitro degradation of poly (50/50 (85/15 L/D)LA/e-cl) and the implications for the use in nerve reconstruction

den Dunnen, W. F. A., Meek, M. F., Grijpma, D. W., Robinson, P. H. & Schakenraad, J. M., 2000, In : Journal of biomedical materials research. 51, 4, p. 575-581

Research output: Contribution to journalArticleAcademicpeer-review

58 Citations (Scopus)

In vivo and in vitro degradation of poly(ether ester) block copolymers based on poly(ethylene glycol) and poly(butylene terephthalate

Deschamps, A. A., van Apeldoorn, A. A., Hayen, H., de Bruijn, J. D., Karst, U., Grijpma, D. W. & Feijen, J., 2004, In : Biomaterials. 25, 2, p. 247-258

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

In vivo application of poly(1,3-trimethylene carbonate) as a scleral buckle in a rabbit model

Wójcik, K., Verdoold, V., de Vos, S. V. N. & Grijpma, D. W., 2011, In : Macromolecular symposia. 309-310, 1 (special issue), p. 68-75

Research output: Contribution to journalArticleAcademicpeer-review

20 Citations (Scopus)

In vivo behavior of epoxy-crosslinked porcine heart valve cusps and walls

van Wachem, P. B., Brouwer, L. A., Zeeman, R., Dijkstra, P. J., Feijen, J., Hendriks, M., Cahalan, P. T. & van Luyn, M. J. A., 2000, In : Journal of biomedical materials research. 53, 1, p. 18-27

Research output: Contribution to journalArticleAcademicpeer-review

205 Citations (Scopus)

In vivo behavior of poly(1,3-trimethylene carbonate) and copolymers of 1,3-trimethylene carbonate with D,L-lactide or e-caprolactone: degradation and tissue response

Pêgo, A. P., van Luyn, M. J. A., Brouwer, L. A., van Wachem, P. B., Poot, A. A., Grijpma, D. W. & Feijen, J., 2003, In : Journal of biomedical materials research. Part A. 67A, 3, p. 1044-1054

Research output: Contribution to journalArticleAcademicpeer-review

31 Citations (Scopus)

In vivo behavior of trimethylene carbonate and e-caprolactone-based (co)polymer networks: degradation and tissue response

Bat, E., Plantinga, J. A., Harmsen, M. C., van Luyn, M. J. A., Feijen, J. & Grijpma, D. W., 2010, In : Journal of biomedical materials research. Part A. 95, 3, p. 940-949

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)
35 Downloads (Pure)

In vivo behaviour of a biodegradable poly (trimethylene carbonate) barrier membrane: A histological study in rats

van Leeuwen, A. C., van Kooten, T. G., Grijpma, D. W. & Bos, R. R. M., 2012, In : Journal of materials science. Materials in medicine. 23, 8, p. 1951-1959

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Rats
Carbonates
Membranes
Collagen
Tissue
77 Citations (Scopus)

In vivo biocompatibility of carbodiimide-crosslinked collagen matrices: effects of crosslink density, heparin immobilization, and bFGF loading

van Wachem, P. B., Plantinga, J. A., Wissink, M. J. B., Beernink, R., Poot, A. A., Engbers, G. H. M., Beugeling, T., van Aken, W. G., Feijen, J. & van Luyn, M. J. A., 2001, In : Journal of biomedical materials research. 55, 3, p. 368-378

Research output: Contribution to journalArticleAcademicpeer-review

Carbodiimides
Fibroblast Growth Factor 2
Fibroblasts
Biocompatibility
Collagen
59 Citations (Scopus)

In vivo compatibility and degradation of cross-linked gelatin gels incorporated in knitted Dacron

Kuijpers, A. J., van Wachem, P. B., van Luyn, M. J. A., Plantinga, J. A., Engbers, G. H. M., Krijgsveld, J., Zaat, S. A. J., Dankert, J. & Feijen, J., 2000, In : Journal of biomedical materials research. 51, 1, p. 136-145

Research output: Contribution to journalArticleAcademicpeer-review

49 Citations (Scopus)

In vivo degradation of calcium phosphate cement incorporated into biodegradable microspheres

Habraken, W. J. E. M., Liao, H. B., Zhang, Z., Wolke, J. G. C., Grijpma, D. W., Mikos, A. G., Feijen, J. & Jansen, J. A., 2010, In : Acta biomaterialia. 6, 6, p. 2200-2211

Research output: Contribution to journalArticleAcademicpeer-review

Calcium phosphate
Microspheres
Cements
Degradation
Composite materials
36 Citations (Scopus)
61 Downloads (Pure)

In vivo degradation of processed dermal sheep collagen evaluated with transmission electron microscopy

van Wachem, P. B., van Luyn, M. J. A., Nieuwenhuis, P., Koerten, H. K., Olde Damink, L., ten Hoopen, H. & Feijen, J., 1991, In : Biomaterials. 12, 2, p. 215-223 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Transmission Electron Microscopy
Collagen
Sheep
Foreign Body Giant Cells
Transmission electron microscopy
28 Citations (Scopus)
33 Downloads (Pure)

In vivo fragmentation of microporous polyurethane- and copolyester elastomer-based vascular prostheses

Hinrichs, W. L. J., Kuit, J., Feil, H., Wildevuur, C. R. H. & Feijen, J., 1992, In : Biomaterials. 13, 9, p. 585-593 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Elastomers
Blood Vessel Prosthesis
Polyurethanes
Prosthetics
Polymers
13 Citations (Scopus)

In vivo performance of microstructured calcium phosphate formulated in novel water-free carriers

Davison, N. L., Yuan, H., de Bruijn, J. D. & Barrere-de Groot, F. YF., 2012, In : Acta biomaterialia. 8, 7, p. 2759-2769

Research output: Contribution to journalArticleAcademicpeer-review

Calcium phosphate
Phosphates
Water
Bone
Ceramics
24 Citations (Scopus)
38 Downloads (Pure)

In vivo quantification of cell-polymer interactions

Schakenraad, J. M., Kuit, J. H., Arends, J., Busscher, H. J., Feijen, J. & Wildevuur, C. R. H., 1987, In : Biomaterials. 8, 3, p. 207-210

Research output: Contribution to journalArticleAcademic

File
33 Citations (Scopus)

In vivo recruitment of hematopoietic cells using stromal cell-derived factor 1 alpha-loaded heparinized three dimensional collagen scaffolds

Bladergroen, B., Siebum, B., Siebers-Vermeulen, K. G. C., van Kuppevelt, T. H., Poot, A. A., Feijen, J., Figdor, C. & Torensma, R., 2009, In : Tissue engineering. Part A. 15, 7, p. 1591-1599

Research output: Contribution to journalArticleAcademicpeer-review

25 Citations (Scopus)
45 Downloads (Pure)

In vivo testing of crosslinked polyethers. I: Tissue reactions and biodegradation

Pol, B. J. M., van der Does, L., Bantjes, A., van Wachem, P. B. & van Luyn, M. J. A., 1996, In : Journal of biomedical materials research. 32, 32, p. 307-320 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Polyethers
Polyethylene oxides
Biodegradation
Tissue
Testing
11 Citations (Scopus)
66 Downloads (Pure)

In vivo testing of crosslinked polyethers. II: Weight loss, IR analysis and swelling behavior after implantation

Pol, B. J. M., van der Does, L., Bantjes, A. & van Wachem, P. B., 1996, In : Journal of biomedical materials research. 32, 32, p. 321-331 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Polyethers
Swelling
Biodegradation
Testing
Polyethylene oxides
10 Citations (Scopus)
73 Downloads (Pure)

Iron(III) chelating resins: VI. Stability constants of iron(III)-ligand complexes on insoluble polymeric matrices

Feng, M., van der Does, L. & Bantjes, A., 1995, In : Journal of applied polymer science. 56, 56, p. 1231-1237

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Chelation
Iron
Resins
Ligands
Sepharose
24 Citations (Scopus)
98 Downloads (Pure)

Iron(III) chelating resins. V. Cross-linked copolymers of 1-(B-acrylamidoethyl)-3-hydroxy-2-methyl-4(1H) pyridinone (AHMP) and N,N-dimethylacrylamide (DMAA) for iron(III) chelation studies

Feng, M., van der Does, L. & Bantjes, A., 1994, In : Journal of applied polymer science. 52, 52, p. 21-28

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Pyridones
Chelation
Iron
Copolymers
Resins
38 Downloads (Pure)

Iron(III)-chelating resins. X. Iron detoxification of human plasma with iron(III)-chelating resins

Feng, M. H., van der Does, L. & Bantjes, A., 1994, In : Nieuwsbrief ABB. 23, 23, p. 63-69

Research output: Contribution to journalArticleAcademic

Open Access
File
Plasma (human)
Detoxification
Chelation
Iron
Resins
9 Citations (Scopus)
39 Downloads (Pure)

Iron(III) chelating resins-IV. Crosslinked copolymer beads of 1-(B-acrylamidoethyl)-3-hydroxy-2-methyl-4(1H)-pyridinone (AHMP) with 2-hydroxyethyl methacrylate (HEMA)

Feng, M-H., van der Does, L. & Bantjes, A., 1994, In : European polymer journal. 1994, 8, p. 941-947

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Pyridones
Chelation
beads
resins
copolymers
40 Citations (Scopus)

Iron oxide-labeled collagen scaffolds for non-invasive MR imaging in tissue engineering

Mertens, M. E., Hermann, A., Bühren, A., Olde-Damink, L., Möckel, D., Gremse, F., Ehling, J., Kiessling, F. & Lammers, T. G. G. M., 2014, In : Advanced functional materials. 24, 6, p. 754-762

Research output: Contribution to journalArticleAcademicpeer-review

Scaffolds (biology)
Iron oxides
Tissue engineering
Collagen
Scaffolds
146 Citations (Scopus)

Linear poly(amido amine)s with secondary and tertiary amino groups and variable amounts of disulfide linkages: synthesis and in vitro gene transfer properties

Lin, C., Zhong, Z., Lok, M. C., Jiang, X., Hennink, W. E., Feijen, J. & Engbersen, J. F. J., 2006, In : Journal of controlled release. 116, 2, p. 130-137

Research output: Contribution to journalArticleAcademicpeer-review

48 Citations (Scopus)

Liposomal clodronate inhibition of osteoclastogenesis and osteoinduction by submicrostructured beta-tricalcium phosphate

Davison, N. L., Gambin, A-L., Layrolle, P., Yuan, H., de Bruijn, J. D. & Barrère-de Groot, F., 2014, In : Biomaterials. 35, 19, p. 5088-5097

Research output: Contribution to journalArticleAcademicpeer-review

37 Citations (Scopus)

Liposomal corticosteroids for the treatment of inflammatory disorders and cancer

Ozbakir, B., Crielaard, B. J., Metselaar, J. M., Storm, G. & Lammers, T. G. G. M., 2014, In : Journal of controlled release. 190, p. 624-636

Research output: Contribution to journalArticleAcademicpeer-review

19 Citations (Scopus)
40 Downloads (Pure)

Liposomal delivery of dexamethasone attenuates prostate cancer bone metastatic tumor growth in vivo

Kroon, J., Kroon, J., Buijs, J. T., van der Horst, G., Cheung, H., van der Mark, M., van Bloois, L., Rizzo, L. Y., Lammers, T. G. G. M., Pelger, R. C., Storm, G., van der Pluijm, G. & Metselaar, J. M., 2015, In : Prostate. 75, 8, p. 815-824

Research output: Contribution to journalArticleAcademicpeer-review

File
1 Citation (Scopus)

Liposomal dexamethasone inhibits tumor growth in an advanced human-mouse hybrid model of multiple myeloma

Deshantri, A. K., Fens, M. H., Ruiter, R. W. J., Metselaar, J. M., Storm, G., van Bloois, L., Varela-Moreira, A., Mandhane, S. N., Mutis, T., Martens, A. C. M., Groen, R. W. J. & Schiffelers, R. M., 28 Feb 2019, In : Journal of controlled release. 296, p. 232-240 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Multiple Myeloma
Dexamethasone
Growth
Neoplasms
Liposomes
7 Citations (Scopus)

Liposomal doxorubicin: the good, the bad and the not-so-ugly

Szebeni, J., Fülöp, G., Dézsi, L., Metselaar, J. M. & Storm, G., 2016, In : Journal of drug targeting. 24, 9, p. 765-767

Research output: Contribution to journalArticleAcademicpeer-review

Hypersensitivity
Nanomedicine
Pharmaceutical Preparations
Pharmacology
Drug Therapy
38 Citations (Scopus)

Liposomal encapsulation of dexamethasone modulates cytotoxicity, inflammatory cytokine response, and migratory properties of primary human macrophages

Bartneck, M., Peters, F. M., Warzecha, K. T., Bienert, M., van Bloois, L., Trautwein, C., Lammers, T. G. G. M. & Tacke, F., 2014, In : Nanomedicine. 10, 6, p. 1209-1220

Research output: Contribution to journalArticleAcademicpeer-review

24 Citations (Scopus)

Liposomal nanomedicines in the treatment of prostate cancer

Kroon, J., Metselaar, J. M., Storm, G. & Pluijm, G., 2014, In : Cancer treatment reviews. 40, 4, p. 578-584

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)

Liposomal prednisolone inhibits tumor growth in a spontaneous mouse mammary carcinoma model

Deshantri, A. K., Kooijmans, S. A. A., Kuijpers, S. A., Coimbra, M., Hoeppener, A., Storm, G., Fens, M. H. A. M. & Schiffelers, R. M., 2016, In : Journal of controlled release. 243, p. 243-249

Research output: Contribution to journalArticleAcademicpeer-review

Prednisolone
Breast Neoplasms
Growth
Neoplasms
MicroRNAs
7 Citations (Scopus)
37 Downloads (Pure)

Liposomal prednisolone inhibits vascular inflammation and enhances venous outward remodeling in a murine arteriovenous fistula model

Wong, C., Bezhaeva, T., Rothuizen, T. C., Metselaar, J. M., de Vries, M. R., Verbeek, F. P. R., Vahrmeijer, A. L., Wezel, A., Zonneveld, A-J., Rabelink, T. J., Quax, P. H. A. & Rotmans, J., 2016, In : Scientific reports. 6, 10 p., 30439.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Arteriovenous Fistula
Prednisolone
Blood Vessels
Inflammation
Tunica Intima
19 Citations (Scopus)

Liposomal prednisolone promotes macrophage lipotoxicity in experimental atherosclerosis

van der Valk, F. M., Schulte, D. M., Meiler, S., Tang, J., Zheng, K. H., van den Bossche, J., Seijkens, T., Laudes, M., de Winther, M., Lutgens, E., Alaarg, A. M. S. A., Metselaar, J. M., Dallinga-Thie, G. M., Mulder, W. J. M., Stroes, E. S. G. & Hamers, A. A. J., 2016, In : Nanomedicine : nanotechnology, biology and medicine. 12, 6, p. 1463-1470

Research output: Contribution to journalArticleAcademicpeer-review

Macrophages
Prednisolone
Atherosclerosis
Nanoparticles
Lipids
6 Citations (Scopus)

Liposomal treatment of experimental arthritis can be monitored noninvasively with a radiolabeled anti-fibroblast activation protein antibody

Geest, T., Laverman, P., Gerrits, D., Walgreen, B., Helsen, M. M., Klein, C., Nayak, T. K., Storm, G., Metselaar, J. M., Koenders, M. I. & Boerman, O. C., 1 Jan 2017, In : Journal of nuclear medicine. 58, 1, p. 151-155 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Experimental Arthritis
Arthritis
Fibroblasts
Liposomes
Antibodies
21 Citations (Scopus)

Liposome encapsulated berberine treatment attenuates cardiac dysfunction after myocardial infarction

Allijn, I. E., Czarny, B. M. S., Wang, X., Chong, S. Y., Weiler, M., Eduardo Da Silva, A., Metselaar, J. M., Lam, C. S. P., Pastorin, G., de Kleijn, D. P. V., Storm, G., Wang, J-W. & Schiffelers, R. M., 2017, In : Journal of controlled release. 247, p. 127-133

Research output: Contribution to journalArticleAcademicpeer-review

Berberine
Liposomes
Myocardial Infarction
Therapeutics
Solubility
13 Citations (Scopus)

Liquid chromatographic-mass spectrometric studies on the in vitro degradation of a poly(ether ester) block copolymer

Hayen, H., Deschamps, A. A., Grijpma, D. W., Feijen, J. & Karst, U., 2004, In : Journal of chromatography A. 1029, 1-2, p. 29-36

Research output: Contribution to journalArticleAcademicpeer-review

52 Downloads (Pure)

Liquid crystalline acrylates and their polymers

de Visser, A. C., de Groot, K., Feijen, J. & Bantjes, A., 1972, In : Journal of Polymer Science: Polymer Letters Edition. 10, 11, p. 851-854

Research output: Contribution to journalArticleAcademic

Open Access
File
1 Citation (Scopus)

Liver fibrosis affects the targeting properties of drug delivery systems to macrophage subsets in vivo

Ergen, C., Niemietz, P. M., Heymann, F., Baues, M., Gremse, F., Pola, R., van Bloois, L., Storm, G., Kiessling, F., Trautwein, C., Luedde, T., Lammers, T. & Tacke, F., 1 Jun 2019, In : Biomaterials. 206, p. 49-60 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Macrophages
Drug Delivery Systems
Liver Cirrhosis
Liver
Myeloid Cells
3 Citations (Scopus)
34 Downloads (Pure)

Local application of a gentamicin-loaded thermo-responsive hydrogel allows for fracture healing upon clearance of a high Staphylococcus aureus load in a rabbit model

ter Boo, G. J. A., Schmid, T., Zderic, I., Nehrbass, D., Camenisch, K., Richards, R. G., Grijpma, D. W., Moriarty, T. F. & Eglin, D., 1 Jan 2018, In : European Cells and Materials. 35, p. 151-164 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Fracture Healing
Hydrogel
Gentamicins
Hydrogels
Staphylococcus aureus
2 Citations (Scopus)

Local sustained delivery of bupivacaine HCL from a new castor oil-based nanoemulsion system

Rachmawati, H., Arvin, Y. A., Asyarie, S., Anggadiredja, K., Tjandrawinata, R. R. & Storm, G., Jun 2018, In : Drug delivery and translational research. 8, 3, p. 515-524 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Castor Oil
Bupivacaine
Local Anesthetics
Analgesia
Pain
6 Citations (Scopus)

Locoregional cancer therapy using polymer-based drug depots

Ramazani, F., van Nostrum, C. F., Storm, G., Kiessling, F., Lammers, T. G. G. M., Hennink, W. E. & Kok, R. J., 2016, In : Drug discovery today. 21, 4, p. 640-647

Research output: Contribution to journalArticleAcademicpeer-review

Polymers
Pharmaceutical Preparations
Neoplasms
Liver Neoplasms
Therapeutics
7 Citations (Scopus)

Long fiber reinforcement of polypropene/polystyrene blends

Inberg, J. P. F., Hunse, P. H., Hunse, P. H. & Gaymans, R. J., 1999, In : Polymer engineering and science. 39, 2, p. 340-

Research output: Contribution to journalArticleAcademicpeer-review

20 Downloads (Pure)

Lowering caveolin-1 expression in human vascular cells inhibits signal transduction in response to shear stress

van der Meer, A. D., Kamphuis, M., Poot, A. A., Feijen, J. & Vermes, I., 2009, In : Journal of cell biology. 532432, p. - 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

File
7 Citations (Scopus)

Low-intensity pulsed ultrasound (LIPUS) and pulsed electromagnetic field (PEMF) treatments affect degeneration of cultured articular cartilage explants

Tan, L., Tan, L., Ren, Y., van Kooten, T. G., Grijpma, D. W. & Kuijer, R., 30 Sep 2015, In : International orthopaedics. 39, 3, p. 549-557

Research output: Contribution to journalArticleAcademicpeer-review

Electromagnetic Fields
Articular Cartilage
Cartilage
Swine
Aggrecans
141 Citations (Scopus)

Low molecular weight linear polyethylenimine-b-poly(ethylene glycol)-b-polyethylenimine triblock copolymers: synthesis, characterization, and in vitro gene transfer properties

Zhong, Z., Feijen, J. & Christensen, L., 2005, In : Biomacromolecules. 6, 6, p. 3440-3448

Research output: Contribution to journalArticleAcademicpeer-review