Faculty of Science and Technology

Research Output 1965 2019

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Meeting Abstract
2019

MICROFABRICATION TECHNOLOGIES FOR CARTILAGE REPAIR

Karperien, M., Jun 2019, In : Annals of the rheumatic diseases. 78, Suppl 2, p. 46-46 SP0151.

Research output: Contribution to journalMeeting AbstractAcademic

2018

A new method for multiplex measurements of biomarkers in synovial fluid aspirates with high sensitivity and extensive quality control

Hendriks, J., Saris, D. & Karperien, M., Apr 2018, In : Osteoarthritis and cartilage. 26, supplement 1, p. S193-S193 374.

Research output: Contribution to journalMeeting AbstractAcademic

Differentiation and validation of human iPSC-derived atrial cardiomyocytes

Sutton, K., El Haou, S., Williams, S., Devalla, H., Stoelzle-Feix, S., Juhasz, K., Doerr, L., Beckler, M., Haarmann, C., George, M., Passier, R., Fertig, N. & Rogers, M., 13 Sep 2018, In : Journal of Pharmacological and Toxicological Methods. 93, p. 168-168 176.

Research output: Contribution to journalMeeting AbstractAcademic

Mitochondrial changes of articular chondrocytes revealed by omics analyses

Bakker, B., Eijkel, G., Mohren, R., Heeren, R., Karperien, M., Post, J. & Cillero-Pastor, B., Apr 2018, In : Osteoarthritis and cartilage. 26, supplement 1, p. S170-S171 332.

Research output: Contribution to journalMeeting AbstractAcademic

3 Citations (Scopus)

RUNX2 and SOX9 protein mobility correlates to osteogenic and chondrogenic differentiation of mesenchymal stem cells

Khurana, S., Govindaraj, K., Karperien, M. & Post, J. N., Apr 2018, In : Osteoarthritis and cartilage. 26, supplement 1, p. S109-S110 201.

Research output: Contribution to journalMeeting AbstractAcademic

SOX9 transcriptional activity is differentially regulated in healthy and osteoarthritic chondrocytes

Govindaraj, K., Khurana, S., Karperien, M. & Post, J. N., Apr 2018, In : Osteoarthritis and cartilage. 26, supplement 1, p. S106-S107 195.

Research output: Contribution to journalMeeting AbstractAcademic

2017

Amyloid micronetworks for cartilage repair

van Dalen, M., Karperien, M., Claessens, M. & Post, J., Apr 2017, In : Osteoarthritis and cartilage. 25, Supplement 1, p. S158-S159 240.

Research output: Contribution to journalMeeting AbstractAcademic

21 Citations (Scopus)

A new highly sensitive method for multiplex measurements of biomarkers in synovial fluid aspirates

Hendriks, J., Stojanovic, I., Saris, D. B. & Karperien, M., Apr 2017, In : Osteoarthritis and cartilage. 25, Supplement 1, p. S99-S99 129.

Research output: Contribution to journalMeeting AbstractAcademic

7 Citations (Scopus)

High oxygen levels increase mitochondrial lipids in human osteoarthritic chondrocytes

Bakker, B., Eijkel, G. B., Heeren, R. M., Karperien, M., Post, J. N. & Cillero-Pastor, B., Apr 2017, In : Osteoarthritis and cartilage. 25, p. S146-S147 212.

Research output: Contribution to journalMeeting AbstractAcademic

Human Ventricular Stem Cell Cardiomyocytes: Validating In Vitro Assays and Screening Platforms for Pro-arrhythmia Risk Prediction

Rogers, M., Ridley, J., El-Haou, S., Williams, S., Webdale, L., Sutton, K., Stoelzle-Feix, S., Thomas, U., Fertig, N., Zwetsloot, T., Devalla, H. D. & Passier, R., 2017, In : Journal of Pharmacological and Toxicological Methods. 88, 2, p. 241-241 0237.

Research output: Contribution to journalMeeting AbstractOther research output

InPulse CrackIT Challenge: Development of An In Vitro Platform Using Physiologically Mature Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Screen for Drug-Induced Effects on Cardiac Contractility

Harris, K., Rossman, E., Xu, X., Clements, P., Mannhardt, I., Hansen, A., Saleem, U., Eschenhagen, T., Hortigon, M., Rodriguez, V. Z., Smith, G., van Meer, B., Tertoolen, L., Mummery, C., Catarino Ribeiro, M., Passier, R., de Korte, T., Vlaming, M., Braam, S., Vickers, C. & 5 othersMosqueira, D., Firth, K., Prodanov, L., George, V. & Denning, C., 2017, In : Journal of Pharmacological and Toxicological Methods. 88, 2, p. 238-238 0227.

Research output: Contribution to journalMeeting AbstractOther research output

10 Downloads (Pure)

Searching for Standards: Multicenter Ring Trials to Evaluate Technologies for the Enrichment of Circulating Tumor Cells

Bender, S., Luetke-Eversloh, M., Neves, R., Stoecklein, N., Terstappen, L., Baggiani, B., Krahn, T., Pantel, K. & Schlange, T., Jan 2017, In : Journal of thoracic oncology. 12, 1, p. S1096 P2.06-039.

Research output: Contribution to journalMeeting AbstractOther research output

Open Access
File
2016
218 Downloads (Pure)

Challenges of immaturity and proliferation in using hPSC-derived cardiomyocytes as disease models

Mummery, C., Birket, M., van Meer, B., Ribeiro, M., Passier, R., Bellin, M., Orlova, V., Davis, G. R., Freund, C., Kosmidis, G. & Tertoolen, L., Nov 2016, In : Human Gene Therapy. 27, 11, p. A11-A11 INV38.

Research output: Contribution to journalMeeting AbstractOther research output

Open Access

Circulating tumor cell (CTC) rise and outcome in patients with metastatic castration-resistant prostate cancer (mCRPC) with low baseline CTC counts.

Lorente, D., Olmos, D., Mateo, J., Zafeiriou, Z., Rescigno, P., Bianchini, D., Mehra, N., Molina, A., Kheoh, T., Baeten, K., Mccormack, R. T., Terstappen, L. W. M. M., Scher, H. I. & de Bono, J. S., 20 May 2016, In : Journal of clinical oncology. 34, 15, p. 5042-5042

Research output: Contribution to journalMeeting AbstractOther research output

Open Access
34 Downloads (Pure)

DKK1AND FRZB are necessary for chondrocyte (RE) differentiation and prevention of cell hypertrophy in 3D cultures of human chondrocytes and human mesenchymal stem cells

Zhong, L., Huang, X., Rodrigues, E., Leijten, J., Verrips, T., El Khattabi, M., Karperien, M. & Post, J., Apr 2016, In : Osteoarthritis and cartilage. 24, supplement 1, p. S142 229.

Research output: Contribution to journalMeeting AbstractOther research output

Open Access
File
Chondrocytes
Stem cells
Mesenchymal Stromal Cells
Cell culture
Hypertrophy

IMI's CANCER-ID: Status of liquid biopsy standardization

Pantel, K., Terstappen, L. W. M. M., Baggiani, B., Krahn, T. & Schlange, T., Jul 2016, In : Cancer research. 76, 14, supplement, p. 1826 Abstract 1826.

Research output: Contribution to journalMeeting AbstractOther research output

Influence of bicarbonate on ventilatory drive in healthy subjects

Mos-Oppersma, E., Doorduin, J., van der Hoeven, J. G., Veltink, P. & Heunks, L. M. A., 2016, In : European respiratory journal. 48, suppl 60, PA5025.

Research output: Contribution to journalMeeting AbstractOther research output

Bicarbonates
Healthy Volunteers
Ventilation
Respiratory Acidosis
Hypoventilation
10 Citations (Scopus)
25 Downloads (Pure)

Lysozyme self-assembles into amyloid networks that support cartilage tissue formation

van Dalen, M., Post, J., Karperien, M. & Claessens, M. M. A. E., Apr 2016, In : Osteoarthritis and cartilage. 24, supplement 1, p. S465 794.

Research output: Contribution to journalMeeting AbstractOther research output

Open Access
File
Cartilage
Muramidase
Catalyst supports
Amyloid
Tissue Engineering
29 Downloads (Pure)

Oxygen regulates lipid profiles in human primary chondrocyte cultures

Bakker, B., Eijkel, G. B., Heeren, R. M. A., Karperien, M., Post, J. N. & Cillero Pastor, B., 2016, In : Osteoarthritis and cartilage. 24, supplement 1, p. S456-S457 779.

Research output: Contribution to journalMeeting AbstractOther research output

Open Access
File
Chondrocytes
Lipids
Oxygen
Cartilage
Osteoarthritis

Speckle tracking echography allows sonographic assessment of diaphragmatic loading

Mos-Oppersma, E., Hatam, N., Doorduin, J., van der Hoeven, J. G., Marx, G., Goetzenich, A., Heunks, L. & Bruells, C., Sep 2016, In : European respiratory journal. 48, suppl 60, PA3564.

Research output: Contribution to journalMeeting AbstractOther research output

Diaphragm
Ultrasonography
Gastric Balloon
Pressure
Muscles

Standardization of technologies for CTC, ctDNA and miRNA enrichment, isolation and analysis for liquid biopsies during the first year of IMI's CANCER-ID

Schlange, T., Stoecklein, N., Neves, R. P., Pleier, S., Bender, S., Brychta, N., Luetke-Eversloh, M. V., Andree, K., Terstappen, L., Krahn, T. & Krahn, T., Jul 2016, In : Cancer research. 76, Abstract 513.

Research output: Contribution to journalMeeting AbstractOther research output

2014

Systematic review of results of kissing stents in the treatment of aortoiliac occlusive disease

Groot Jebbink, E., Lardenoije, J-W., Holewijn, S. & Reijnen, M., 2014, In : Artery research. 8, 4, p. 146

Research output: Contribution to journalMeeting AbstractAcademic

Stents
Search Engine
Therapeutics
Dilatation
Pathologic Constriction
2013

Aggregation conditions strongly influence the molecular composition of alpha-synuclein oligomers

Zijlstra, N., Blum, C. & Subramaniam, V., 2013, In : European biophysics journal. 42, Suppl. 1, p. S200-S200

Research output: Contribution to journalMeeting AbstractOther research output

alpha-Synuclein
Photobleaching
Parkinson Disease
Dopamine
Protein Aggregates

Alpha-synuclein fibrillization plays essential role in membrane disruption

Chaudhary, H., Subramaniam, V. & Claessens, M., 2013, In : European biophysics journal. 42, Suppl. 1, p. S148-S148

Research output: Contribution to journalMeeting AbstractOther research output

Synucleins
alpha-Synuclein
Membranes
Unilamellar Liposomes
Amyloid

Alpha-synuclein oligomers distinctively permeabilize model plasma and mitochondrial membranes

Stefanovic, A. N. D., Stöckl, M. T., Claessens, M. M. A. E. & Subramaniam, V., 2013, In : European biophysics journal. 42, Suppl. 1, p. S156-S156 P-464.

Research output: Contribution to journalMeeting AbstractOther research output

alpha-Synuclein
Mitochondrial Membranes
Cell Membrane
Artificial Membranes
Membranes

Getting a grip on alpha-synuclein amyloid oligomers - single molecule approaches

Subramaniam, V., 2013, In : European biophysics journal. 42, Suppl. 1, p. S108-S108 O-277.

Research output: Contribution to journalMeeting AbstractOther research output

alpha-Synuclein
Amyloid
Photobleaching
human SNCA protein

Repeats in the α-synuclein sequence determine its conformation on membranes

Shvadchak, V. V. & Subramaniam, V., 2013, In : European biophysics journal. 42, Suppl. 1, p. S187-S187

Research output: Contribution to journalMeeting AbstractAcademic

Synucleins
Amino Acid Repetitive Sequences
Membranes
Amyloidogenic Proteins
Amino Acids
2012

Circulating tumor cells as a possible prognostic tool in newly diagnosed non-metastatic colorectal cancer?

Scholten, L., Terstappen, L. W. M. M., van der Palen, J., Mastboom, W., Tibbe, A., Vermes, I. & de Groot, M., 19 Jan 2012, In : Journal of clinical oncology. 30, 4_suppl., p. 395-395

Research output: Contribution to journalMeeting AbstractOther research output

Open Access
Circulating Neoplastic Cells
Colorectal Neoplasms
Disease-Free Survival
Survival
Recurrence
12 Downloads (Pure)

Layer-by-layer biofabrication using Laser-Assisted-Bioprinting and electrospinning enhances cell proliferation in vitro and in vivo

Catros, S., Nandakumar, A., Ziane, S., Keriquel, V., Moroni, L., van Blitterswijk, C., Rousseau, B., Amedee, J., Guillemont, F. & Fricain, J-C., Jun 2012, In : Histology and histopathology. 26, Suppl. 1, p. 40-41

Research output: Contribution to journalMeeting AbstractOther research output

Open Access
File

Ventilation area measured with eit in order to optimize peep settings in mechanically ventilated patients

Blankman, P., Groot Jebbink, E., Preis, C., Bikker, I. & Gommers, D., 2012, In : Intensive care medicine. 38, Supplement 1, p. S44 0139.

Research output: Contribution to journalMeeting AbstractOther research output

Ventilation
Electric Impedance
Tomography
Anthracosis
One-Lung Ventilation
2011

Mixed matrix membranes for toxin removal from blood

Tijink, M. S. L., Sun, J., ter Beek, O., Saiful, S., Borneman, Z., Wessling, M. & Stamatialis, D. F., 23 Jul 2011, In : International journal of artificial organs. 33, 7, p. 460-460

Research output: Contribution to journalMeeting AbstractAcademic

Blood
Membranes
Adsorption
Artificial Kidneys
Carbon
13 Downloads (Pure)

Non-invasive quality control for ISLET transplantation using Raman spectroscopy

Hilderink, J., de Koning, E. J. P., Engelse, M. A., Otto, C., van Blitterswijk, C. A., van Apeldoorn, A. A. & Karperien, M., 7 Jun 2011, In : Histology and histopathology. 26, Suppl. 1, p. 308-308

Research output: Contribution to journalMeeting AbstractOther research output

Open Access
File

TCT-448: Scanning Electron Microscopic Observation of Coating Irregularities and Their Precursors in Unexpanded Durable Polymer-Based Drug-Eluting Stents

Basalus, M. W. Z., Tandjung, K., Sen, H., van Westen, T., Grijpma, D. W., van Apeldoorn, A. A. & von Birgelen, C., 8 Nov 2011, In : Journal of the American College of Cardiology. 58, 20, Suppl., p. B122-B122 1 p.

Research output: Contribution to journalMeeting AbstractAcademic

Drug-Eluting Stents
Polymers
Electrons
Electron Scanning Microscopy
Taxus
22 Citations (Scopus)
11 Downloads (Pure)

The role of hyrolytic enzymes and reactive oxygen species in an in vitro model of macrophage-mediated degradation of poly(trimethylene carbonate) network films

van Kooten, T. G., Bat, E., Kuijer, R. & Grijpma, D. W., 7 Jun 2011, In : Histology and histopathology. 26, Suppl. 1, p. 67-68

Research output: Contribution to journalMeeting AbstractOther research output

Open Access
File
2010

Engineering of quantum dot pattern luminescence via Energy transfer for sensing applications

Dorokhin, D., Hsu, S. H., Tomczak, N., Blum, C., Subramaniam, V., Huskens, J., Reinhoudt, D. N., Velders, A. H. & Vancso, G. J., 1 Jan 2010, In : European Cells and Materials. 20, SUPPL.3, 1 p.

Research output: Contribution to journalMeeting AbstractAcademic

2008

Chitosan-based hydrogels as extracellular matrix for cartilage tissue engineering: in vitro biological evaluation

Moreira Teixeira, L., Jin, R., Dijkstra, P. J., Feijen, J., van Blitterswijk, C. & Karperien, H. B. J., 22 Jun 2008, In : Tissue engineering. Part A. 14, 5, p. 711-711

Research output: Contribution to journalMeeting AbstractAcademic

Effective Nutrient Supply through Multi-Layer Scaffolds

Papenburg, B., Liu, J., de Vries, I-J., Stamatialis, D., de Boer, J., van Blitterswijk, C. & Wessling, M., 22 Jun 2008, In : Tissue engineering. Part A. 14, 5, p. 726-726

Research output: Contribution to journalMeeting AbstractAcademic

Flexible micropatterned porous scaffolds

Papenburg, B., Schüller, S., Stamatialis, D., Grijpma, D., de Boer, J., van Blitterswijk, C. & Wessling, M., 2008, In : Tissue engineering. Part A. 14, 5, p. 855-855

Research output: Contribution to journalMeeting AbstractAcademic

Genetically Engineered KSFrt Mesenchymal Progenitors Cells in Combination with Whole Body Optical Imaging Provide an Excellent Model to Study Effects on Cell Fate, Bone and Cartilage Formation and Biomaterials

de Rooij, K. E., Sips, H. C. M., van der Horst, G., Que, I., van der Wee-Pals, L., Löwik, C. W. G. M. & Karperien, M., 22 Jun 2008, In : Tissue engineering. Part A. 14, 5, p. 739-739

Research output: Contribution to journalMeeting AbstractAcademic

High-Throughput Biological Screening of Cell-Surface Topography Interactions

Unadkat, H. V., Papenburg, B. J., Stamatialis, D., Wessling, M., van Blitterswijk, C. A. & de Boer, J., 2008, In : Tissue engineering. Part A. 14, 5, p. 858-858

Research output: Contribution to journalMeeting AbstractAcademic

6 Downloads (Pure)

Materiomics: Dealing with complexity in tissue engineering

van Blitterswijk, C., Stamatialis, D., Unadkat, H. V., Papenburg, B. J., Rouwkema, J., Truckenmüller, R. K., van Apeldoorn, A. A., Wessling, M. & de Boer, J., 2008, In : Tissue engineering. Part A. 14, 5, p. 796-796

Research output: Contribution to journalMeeting AbstractAcademic

Membranes for Bioartificial Organs and Tissue Engineering

Stamatialis, D., Papenburg, B., Bettahalli, M. S., Girones, M., de Boer, J., van Blitterswijk, C. & Wessling, M., 22 Jun 2008, In : Tissue engineering. Part A. 14, 5, p. 755-755

Research output: Contribution to journalMeeting AbstractAcademic

Mesenchymal stem cells differentiate towards endothelial cells in a prevascularized bone tissue engineering

Rouwkema, J., Rivron, N. C., Bettahalli, N. M. S., Stamatialis, D., Wessling, M. & van Blitterswijk, C. A., 22 Jun 2008, In : Tissue engineering. Part A. 14, 5, p. 756-756

Research output: Contribution to journalMeeting AbstractAcademic

44 Downloads (Pure)

Modulating the skin barrier function by DMSO: molecular dynamics simulations of hydrophilic and hydrophobic transmembrane pores

den Otter, W. K., Notman, R., Anwar, J., Noro, M. G. & Briels, W. J., 2008, In : Chemistry and physics of lipids. 154, supplement, p. S2-S3

Research output: Contribution to journalMeeting AbstractOther research output

File
Molecular Dynamics Simulation
Dimethyl Sulfoxide
Molecular dynamics
Skin
Computer simulation
2007

Mapping nano-landscape of pathogen recognition receptor DC-SIGN and lipid rafts on dendritic cells

van Zanten, T., Zambrano, J., Koopman, M., Cambi, A., Joosten, B., Figdor, C. G. & Garcia Parajo, M. F., 2007, In : European biophysics journal. 36, 1, p. S181-S181 P-500.

Research output: Contribution to journalMeeting AbstractOther research output

Dendritic Cells
Lipids
Clathrin
Antigens
Endocytosis

Single molecule NSOM microscopy resolves distinct nano-scale compartments on the cell membrane

Garcia Parajo, M. F., Cambi, A., Bakker, G. J., Koopman, M., Joosten, B. & Figdor, C. G., 2007, In : European biophysics journal. 36, 1, p. S174-S174

Research output: Contribution to journalMeeting AbstractOther research output

Microscopy
Lymphocyte Function-Associated Antigen-1
Cell Membrane
Lipids
Transferrin Receptors
2006

Development of active, and stable water-gas-shift reaction catalysts for fuel cell applications

Azzam, K. G. H., Babich, I. V., Seshan, K. I. & Lefferts, L., 2006, In : Abstracts of papers of the American Chemical Society. 231, 1 p.

Research output: Contribution to journalMeeting AbstractOther research output

Water gas shift
Fuel cells
Catalysts
Carbon Monoxide
Precious metals

Steam reforming of biomass derived oxygenates to hydrogen: Importance of metal-support boundary

Takanabe, K., Aika, K., Seshan, K. I. & Lefferts, L., 2006, In : Abstracts of papers of the American Chemical Society. 231, 1 p.

Research output: Contribution to journalMeeting AbstractOther research output

Steam reforming
Hydrogen
Biomass
Metals
Catalysts
2004

Sustainable hydrogen from bio-oil - Catalytic steam reforming of acetic acid as a model oxygenate

Takanabe, K., Seshan, K., Lefferts, L. & Aika, K., 2004, In : Abstracts of papers of the American Chemical Society. 228, 1, p. FUEL-152

Research output: Contribution to journalMeeting AbstractOther research output

Catalytic reforming
Steam reforming
Acetic acid
Acetic Acid
Hydrogen