Research Output 1984 2020

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Patent
2018
22 Downloads (Pure)

Device and Method for the Continuous Trapping of Circulating Tumor Cells

Stevens, M., Nijsink, F. T., van Dalum, G., Tibbe, A. G. J., Broekmaat, J. J. & Terstappen, L. W. M. M., 2018, IPC No. US 62/485,414, Bromhead Johnson, Patent No. PCT/EP2018/059607, 13 Apr 2018

Research output: Patent

Open Access
File
2015

Methods and means for detecting cells using surface plasmon resonance

Vidarsson, G. & Schasfoort, R. B. M., 2015, (Submitted) Patent No. US Pat20,150,323,525

Research output: Patent

2014

A simple and affordable method for immunophenotyping using a microfluidic chip sample preparation with image cytometry

Beck, M. & Terstappen, L. W. M. M., 6 Feb 2014, IPC No. G01N 33/ 50 A I, Patent No. US2014038230, Priority date 8 May 2011, Priority No. US201113817180

Research output: Patent

Microfluidics
Flow cytometry
Fluids
Capillary flow
T-cells
2013

A simple and affordable method for immuophenotyping using a microfluidic chip sample preparation with image cytometry

Beck, M. & Terstappen, L. W. M. M., 1 May 2013, IPC No. G01N 33/ 558 A I, Patent No. EP2585578, Priority date 8 May 2011, Priority No. WO2011US35667

Research output: Patent

Imaging of immunomagnetically enriched rare cells.

Scholtens, T. M., Greve, J., Tibbe, A. G. J., Terstappen, L. W. M. M. & Schreuder, F., 29 Oct 2013, (Submitted) Patent No. US 12/467,932, Priority date 18 May 2009

Research output: Patent

Mouse models for osteoinduction and heterotopic ossification

Barradas, A. M. C. & de Boer, J., 31 Jul 2013, (In preparation) Patent No. EP2620055, Priority date 31 Jul 2013

Research output: Patent

2012

Analysis of circulating tumor cells, fragments, and debris

Rao, G. C., Larson, C., Repollet, M., Rutner, H., Terstappen, L. W. M. M., O' Hara, S. M. & Gross, S., 11 Dec 2012, (Submitted) Patent No. US 8,329,422 B2, Priority date 11 Dec 2012

Research output: Patent

Method and apparatus for imaging target components in a biological sample using permanent magnets

Tibbe, A. G. J. & Terstappen, L. W. M. M., 7 Feb 2012, (Submitted) Patent No. 8,110,101 B2, Priority date 7 Feb 2012

Research output: Patent

Methods and algorithms for cell enumeration in a low-cost cytometer

Coumans, F. A. W., Greve, J., Modica, F. P., Terstappen, L. W. M. M., Tibbe, A. G. J. & Verrant, J. A., 29 May 2012, (Submitted) Patent No. US 8,189,899 B2, Priority date 29 May 2012

Research output: Patent

Methods and algorithms for cell enumeration in a low-cost cytometer.

Droog, E., Gohel, D., Tibbe, A. G. J., Greve, J. & Terstappen, L. W. M. M., 6 Feb 2012, (Submitted) Patent No. 8,128,890, Priority date 6 Feb 2012

Research output: Patent

2011

Analysis of Circulating Tumor Cells, Fragments, and Debris

Rao, G. C., Larson, C., Repollet, M., Rutner, H., Terstappen, L. W. M. M., O' Hara, S. M. & Gross, S., 4 Jan 2011, (Submitted) Patent No. 7,863,012 B2, Priority date 4 Jan 2011

Research output: Patent

ANALYZERS WITH TIME VARIATION BASED ON COLOR-CODED SPATIAL MODULATION

Martini, J., Kiesel, P., Huck, M., Bern, M., Johnson Noble, M., Bassler, M., Beck, M. & Bern Marshall, W., 15 Sep 2011, IPC No. G01N 21/ 64 A I, Patent No. US2011222062, Priority date 20 May 2011, Priority No. US201113113021

Research output: Patent

analyzers
color
modulation
filters
assembly

method for assessing disease states by profile analysis of isolated circulating endothelial cells

Connelly, M. C., Doyle, G. V., Rao, G. C. & Terstappen, L. W. M. M., 8 Mar 2011, (Submitted) Patent No. US 7901950 B2, Priority date 8 Mar 2011

Research output: Patent

11 Downloads (Pure)

Methods and algorithms for cell enumeration in low-cost cytometer.

Tibbe, A. G. J., Greve, J., Gohel, D., Droog, E. J. & Terstappen, L. W. M. M., 17 May 2011, (Submitted) Patent No. 7,943,397, Priority date 17 May 2011

Research output: Patent

File
Fluids
Costs
Flow cytometry
CCD cameras
Image analysis

Microsieve Filter and Methods for use in Optical Analysis

Tibbe, A. G. J., van Rijn, C. J. M. & Terstappen, L. W. M. M., 2 Mar 2011, (In preparation) Patent No. 103862, Priority date 2 Mar 2011

Research output: Patent

Simple and affordable method for immunophenotyping using a microfluidic chip sample preparation with image cytometry.

Beck, M. & Terstappen, L. W. M. M., 8 May 2011, (In preparation) Patent No. 61/332,763, Priority date 8 May 2011

Research output: Patent

2010

A Method For Assessing Disease States By Profile Analysis of Isolated Circulating Endothelial Cells

Connelly, M. C., Doyle, G. V., Rao, G. C. & Terstappen, L. W. M. M., 1 Oct 2010, (Submitted) Patent No. US 11/701763, Priority date 1 Oct 2010

Research output: Patent

Causing Relative Motion

Kiesel, P., Beck, M., Bassler, M. & Johnson Noble, M., 24 Jun 2010, IPC No. G01N 21/ 01 A I, Patent No. US2010157291, Priority date 18 Dec 2008, Priority No. US20080337796

Research output: Patent

Sensors
Fluidics
Flow of fluids
Modulation
Scanning

FLOW SCHEMES FOR ENHANCED LIGHT-TARGET INTERACTION IN FLUIDIC CHANNELS

Beck, M., Kiesel, P., Bassler, M. & Burgel, T., 11 Mar 2010, IPC No. G01N 1/ 20 A I, Patent No. US2010060892, Priority date 5 Sep 2008, Priority No. US20080205730

Research output: Patent

Fluidics
14 Downloads (Pure)

Magnetic separation apparatus and methods

Tibbe, A. G. J., Terstappen, L. W. M. M. & Scholtens, T. M., 23 Feb 2010, (Submitted) Patent No. 7,666,308 B2, Priority date 23 Feb 2010

Research output: Patent

File
Magnetic separation
Patents and inventions
Magnets
Fluids
Chemical analysis
9 Downloads (Pure)

Method and apparatus from imaging target components in a biological sample using permanent magnets

Tibbe, A. G. J. & Terstappen, L. W. M. M., 9 Nov 2010, (Submitted) Patent No. 7,828,968 B2, Priority date 9 Nov 2010

Research output: Patent

File
inventions
permanent magnets
blood
magnets
containers
9 Downloads (Pure)

Methods and Algorithms for cell enumeration in low-cost cytometer

Coumans, F. A. W., Greve, J., Modica, F. P., Terstappen, L. W. M. M., Tibbe, A. G. J. & Verrant, J. A., 27 Jul 2010, (Submitted) Patent No. US 7,764,821 B2, Priority date 27 Jul 2010

Research output: Patent

File
Fluids
Costs
Flow cytometry
CCD cameras
Image analysis

Obtaining Sensing Results and/or Data in Response to Object Detection

Kiesel, P., Beck, M., Martini, J., Bassler, M. & Johnson Noble, M., 24 Jun 2010, IPC No. G01J 1/ 20 A I, Patent No. US2010155572, Priority date 18 Dec 2008, Priority No. US20080337771

Research output: Patent

actuators
coders
coding
waveforms
sensors

Obtaining Sensing Results Indicating Time Variation

Kiesel, P., Martini, J., Bassler, M., Beck, M. & Johnson Noble, M., 24 Jun 2010, IPC No. G06F 15/ 00 A I, Patent No. US2010155577, Priority date 18 Dec 2008, Priority No. US20080337737

Research output: Patent

Scanning
Flow cytometry
Sensors
2009

Obtaining sensing results and/or data in response to object detection

Kiesel, P., Beck, M., Martini, J., Bassler, M., Johnson, N. M., Hegyi, A. & Buergel, T., 5 Aug 2009, IPC No. G01N 21/ 05 A I, Patent No. EP2085763, Priority date 18 Dec 2008, Priority No. US20080337771

Research output: Patent

actuators
coders
coding
waveforms
sensors

Producing Filters With Combined Transmission and/or Reflection Functions

Bassler, M., Kiesel, P., Beck, M., Hegyi, A., Buergel, T. & Johnson Noble, M., 6 Aug 2009, IPC No. G02F 1/ 01 A I, Patent No. US2009195852, Priority date 4 Feb 2008, Priority No. US20080025394

Research output: Patent

filters
set theory
periodic functions
output
optical filters

Producing Time Variation In Emanating Light

Kiesel, P., Beck, M., Bassler, M. & Johnson Noble, M., 6 Aug 2009, IPC No. G01N 21/ 64 A I, Patent No. US2009194705, Priority date 31 Jan 2008, Priority No. US20080023436

Research output: Patent

excitation
color
actuators
intervals
causes

Transmitting/Reflecting Emanating Light With Time Variation

Bassler, M., Beck, M., Kiesel, P., Hegyi, A., Buergel, T. & Johnson Noble, M., 6 Aug 2009, IPC No. G01N 21/ 00 A I, Patent No. US2009195773, Priority date 1 Feb 2008, Priority No. US20080024490

Research output: Patent

filters
assembly
waveforms
2008

Device and method for modulating light

Beck, M., Santos, P. V. & Morais De Lima, M. J., 12 Nov 2008, IPC No. G02F 1/ 21 A N, Patent No. EP1990677, Priority date 7 May 2007, Priority No. EP20070009188

Research output: Patent

Open Access
modulators
output
phase modulation
intervals
pulses
2007
10 Downloads (Pure)

Devices and methods to image objects

Tibbe, A. G. J., Greve, J., Terstappen, L. W. M. M. & de Grooth, B. G., 16 Oct 2007, Patent No. US 7,282,180 B2

Research output: Patent

File
1999

Increased separation efficiency via controlled aggregation of magnetic nanoparticles

Liberti, P. A., Rao, G. C. & Terstappen, L. W. M. M., 12 Jul 1999, Immunivest Corp, Patent No. US6623982B1, 12 Jul 1999, Priority date 12 Jul 1999

Research output: Patent

Methods for enhancing binding interactions between members of specific binding pairs

Rao, C., Terstappen, L. W. M. M. & Liberti, P. A., 29 Jan 1999, Patent No. US6551843B1, Priority date 29 Jan 1999

Research output: Patent

1998

Apparatus and methods for magnetic separation

Terstappen, L. W. M. M., Doyle, G. V., Liberti, P. A. & Dolan, G. J., 18 Aug 1998, Patent No. US6361749B1, Priority date 18 Aug 1998

Research output: Patent

Methods and reagents for the rapid and efficient isolation of circulating cancer cells

Terstappen, L. W. M. M., Rao, C., Uhr, J. W., Racila, E. V. & Liberti, P. A., 12 Feb 1998, Patent No. US6645731B2, Priority date 12 Feb 1998

Research output: Patent

1997

Apparatus and methods for capture and analysis of particulate entities

Terstappen, L. W. M. M. & Rao, G. C., 25 Mar 1997, Patent No. US7332288B2, Priority date 25 Mar 1997

Research output: Patent

1996

Magnetic separation apparatus and methods

Terstappen, L. W. M. M. & Dolan, G., 7 Jun 1996, Patent No. US6790366B2, Priority date 7 Jun 1996

Research output: Patent

Magnetic separation apparatus and methods employing an internal magnetic capture gradient and an external transport force

Dolan, G. J. & Terstappen, L. W. M. M., 7 Jun 1996, Immunivest Corp, Patent No. US5985153A, Priority date 7 Jun 1996

Research output: Patent

Methods for biological substance analysis employing internal magnetic gradients separation and an externally-applied transport force

Terstappen, L. W. M. M. & Liberti, P. A., 7 Jun 1996, Immunivest Corp, Patent No. US6013188A, Priority date 7 Jun 1996

Research output: Patent

Method to select and transfect cell subpopulations

Terstappen, L. W. M. M., 2 Aug 1996, Immunivest Corp, Patent No. US6228624B1, Priority date 2 Aug 1996

Research output: Patent

Quantitative cell analysis methods employing magnetic separation

Terstappen, L. W. M. M. & Liberti, P. A., 7 Jun 1996, Immunivest Corp, Patent No. US5993665A, Priority date 7 Jun 1996

Research output: Patent

1995

Phage antibodies

Terstappen, L. W. M. M. & Logtenberg, T., 7 Jun 1995, Becton Dickinson and Co., Patent No. US6265150B1, 7 Jun 1995

Research output: Patent

1993
17 Citations (Scopus)

Automatic lineage assignment of acute leukemias by flow cytometry

Verwer, B. J. H. & Terstappen, L. W. M. M., 9 Feb 1993, Becton Dickinson and Co., Patent No. US5605805A, Priority date 9 Feb 1993

Research output: Patent

Method to distinguish hematopoietic progenitor cells

Olweus, J., Lund-Johansen, F. & Terstappen, L. W. M. M., 4 Nov 1993, Becton Dickinson and Co., Patent No. US6555324B1, Priority date 4 Nov 1993

Research output: Patent

1992

Apparatus for indirect fluorescent assay of blood samples

Levine, R. A., Wardlaw, S. C., Terstappen, L. W. M. M., Mercolino, T. J. & Recktenwald, D. J., 30 Oct 1992, Becton Dickinson and Co., Patent No. US5342790A, Priority date 30 Oct 1992

Research output: Patent

Assay of blood or other biologic samples for target analytes

Levine, R. A., Wardlaw, S. C., Terstappen, L. W. M. M., Manion, K. L., Rodriguez, R. R., Malick, A. P., Dhanesar, S., Lovell, S. J. & Ozinskas, A. J., 30 Oct 1992, Becton Dickinson and Co., Patent No. US5834217A, 30 Oct 1992, Priority date 30 Oct 1992

Research output: Patent

Indirect fluorescent assay of blood samples

Levine, R. A., Wardlaw, S. C., Terstappen, L. W. M. M., Mercolino, T. J. & Recktemwald, D. J., 30 Oct 1992, Becton Dickinson and Co., Patent No. US5460979A, Priority date 30 Oct 1992

Research output: Patent

Multidimensional cell differential analysis

Terstappen, L. W. M. M. & Chen, C. H., 22 Jan 1992, Becton Dickinson and Co., Patent No. US6287791B1, Priority date 22 Jan 1992

Research output: Patent

1991

Affinity-binding separation and release of one or more selected subset of biological entities from a mixed population thereof

Terstappen, L. W. M. M., Rao, G. C., Gohel, D., Feeley, B., Gross, S., Church, E. & Liberti, P. A., 25 Mar 1991, Immunivest Corp, Patent No. US5646001A, Priority date 25 Mar 1991

Research output: Patent

Method for the classification and monitoring of leukemias

Terstappen, L. W. M. M., 12 Jul 1991, Becton Dickinson and Co., Patent No. US5234816A, Priority date 12 Jul 1991

Research output: Patent