C.L. Mummery

2019

303 Downloads (Pure)

Advanced in vitro models of vascular biology: Human induced pluripotent stem cells and organ-on-chip technology

Cochrane, A., Albers, H. J., Passier, R., Mummery, C. L., van den Berg, A., Orlova, V. V. & van der Meer, A., 1 Feb 2019, In : Advanced drug delivery reviews. 140, p. 68-77 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

Induced Pluripotent Stem Cells

Blood Vessels

Technology

Microfluidics

Pharmaceutical Preparations

10 Citations (Scopus)

13 Downloads (Pure)

Personalised organs-on-chips: functional testing for precision medicine

Van Den Berg, A., Mummery, C. L., Passier, R. & Van der Meer, A. D., 21 Jan 2019, In : Lab on a chip. 19, 2, p. 198-205 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

Precision Medicine

Medicine

Physiology

Testing

Cell culture

1 Citation (Scopus)

6 Downloads (Pure)

Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes

van Meer, B. J., Krotenberg, A., Sala, L., Davis, R. P., Eschenhagen, T., Denning, C., Tertoolen, L. G. J. & Mummery, C. L., 20 Sep 2019, In : Nature communications. 10, 1, 9 p., 4325.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

Induced Pluripotent Stem Cells

Excitation Contraction Coupling

Cardiac Myocytes

Action Potentials

contraction

2018

1 Citation (Scopus)

Decreased Expression of Vascular Endothelial Growth Factor Receptor 1 Contributes to the Pathogenesis of Hereditary Hemorrhagic Telangiectasia Type 2

Thalgott, J. H., Dos-Santos-Luis, D., Hosman, A. E., Martin, S., Lamandé, N., Bracquart, D., Srun, S., Galaris, G., de Boer, H. C., Tual-Chalot, S., Kroon, S., Arthur, H. M., Cao, Y., Snijder, R. J., Disch, F., Mager, J. J., Rabelink, T. J., Mummery, C. L., Raymond, K. & Lebrin, F., 4 Dec 2018, In : Circulation. 138, 23, p. 2698-2712 15 p.

Research output: Contribution to journal › Article › Academic › peer-review

Vascular Endothelial Growth Factor Receptor-1

Blood Vessels

Mycoplasma pulmonis

Pathologic Neovascularization

Haploinsufficiency

Decreased expression of VEGFR1 contributes to the pathogenesis of Hereditary Hemorrhagic Telangiectasia type 2

Lebrin, F., Thalgott, J., Dos-Santos-Luis, D., Hosman, A. E., Martin, S., Bracquart, D., Srun, S., Lamando, N., Carette, M. F., Oh, S. P., Westermann, C. J., Snijder, R. J., Mager, J. J., Mummery, C. L., Rabelink, T. J. & Raymond, K., 1 Feb 2018, In : Angiogenesis. 21, 1, p. 126-126

Research output: Contribution to journal › Meeting Abstract › Academic

Human induced pluripotent stem cell-derived endothelial cells in thrombosis-on-a-chip devices

Albers, H. J., da Silva Simão, J. P., Middelkamp, H. H. T., Mummery, C. L., Passier, R., van den Berg, A., Orlova, V. V. & van der Meer, A. D., 11 Nov 2018. 1 p.

Research output: Contribution to conference › Poster › Academic

12 Citations (Scopus)

54 Downloads (Pure)

Interpretation of field potentials measured on a multi electrode array in pharmacological toxicity screening on primary and human pluripotent stem cell-derived cardiomyocytes

Tertoolen, L. G. J., Braam, S. R., van Meer, B. J., Passier, R. & Mummery, C. L., 18 Mar 2018, In : Biochemical and biophysical research communications. 497, 4, p. 1135-1141 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

Pluripotent Stem Cells

Stem cells

Cardiac Myocytes

Toxicity

Screening

Isogenic induced pluripotent stem cells (IPSCS) derived from mosaic hereditary hemorrhagic telangiectasia type 1 (HHT1) patient

Orlova, V. V., Cao, X., Freund, C., Sanchez-Duffhues, G., Hawinkels, L., Petrus-Reurer, S., van den Hil, F. E., Disch, F., Snijder, R. J., Westermann, C. J. J., Mager, J. J., ten Dijke, P., van Amstel, P. J. K. & Mummery, C. L., 1 Feb 2018, In : Angiogenesis. 21, 1, p. 129-129

Research output: Contribution to journal › Meeting Abstract › Academic

Metabolic characterization of hiPSC-derived cardiomyocytes from patients suffering from infantile cardiomyopathy

van Helden, R. W. J., Bellin, M., Orlova, V. & Mummery, C. L., 1 Dec 2018, In : Human Gene Therapy. 29, 12, p. A132-A132 P355.

Research output: Contribution to journal › Meeting Abstract › Academic

18 Citations (Scopus)

28 Downloads (Pure)

Musclemotion: A versatile open software tool to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo

Sala, L., Van Meer, B. J., Tertoolen, L. G. J., Bakkers, J., Bellin, M., Davis, R. P., Denning, C., Dieben, M. A. E., Eschenhagen, T., Giacomelli, E., Grandela, C., Hansen, A., Holman, E. R., Jongbloed, M. R. M., Kamel, S. M., Koopman, C. D., Lachaud, Q., Mannhardt, I., Mol, M. P. H., Mosqueira, D. & 7 othersOrlova, V. V., Passier, R., Catarino Ribeiro, M., Saleem, U., Smith, G. L., Burton, F. L. & Mummery, C. L., 2 Feb 2018, In : Circulation research. 122, 3, p. e5-e16

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

Muscle Contraction

Cardiac Myocytes

Myocardium

Software

Pluripotent Stem Cells

12 Citations (Scopus)

5 Downloads (Pure)

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network

Anderson, D. J., Kaplan, D. I., Bell, K. M., Koutsis, K., Haynes, J. M., Mills, R. J., Phelan, D. G., Qian, E. L., Leitoguinho, A. R., Arasaratnam, D., Labonne, T., Ng, E. S., Davis, R. P., Casini, S., Passier, R., Hudson, J. E., Porrello, E. R., Costa, M. W., Rafii, A., Curl, C. L. & 9 othersDelbridge, L. M., Harvey, R. P., Oshlack, A., Cheung, M. M., Mummery, C. L., Petrou, S., Elefanty, A. G., Stanley, E. G. & Elliott, D. A., 10 Apr 2018, In : Nature communications. 9, 1, 1373.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

stem cells

Gene Regulatory Networks

mutations

genes

Stem cells

The Next Chapter for Stem Cell Reports

Mummery, C., 11 Dec 2018, In : Stem cell reports. 11, 6, p. 1303-1304 2 p.

Research output: Contribution to journal › Editorial › Academic › peer-review

2017

8 Citations (Scopus)

34 Downloads (Pure)

A COUP-TFII Human Embryonic Stem Cell Reporter Line to Identify and Select Atrial Cardiomyocytes

Schwach, V., Verkerk, A. O., Mol, M., Monshouwer-Kloots, J. J., Devalla, H. D., Orlova, V. V., Anastassiadis, K., Mummery, C. L., Davis, R. P. & Passier, R., 12 Dec 2017, In : Stem cell reports. 9, 6, p. 1765-1779 15 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

Ovalbumin

Stem cells

Cardiac Myocytes

Transcription Factors

Pluripotent Stem Cells

6 Citations (Scopus)

95 Downloads (Pure)

Electrophysiological analysis of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) using multi-electrode arrays (MEAs)

Sala, L., Ward-van Oostwaard, D., Tertoolen, L. G. J., Mummery, C. L. & Bellin, M., 12 May 2017, In : Journal of visualized experiments. 2017, 123, e55587.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

Pluripotent Stem Cells

Stem cells

Cardiac Myocytes

Electrodes

Induced Pluripotent Stem Cells

21 Citations (Scopus)

5 Downloads (Pure)

FANTOM5 CAGE profiles of human and mouse samples

Noguchi, S., Arakawa, T., Fukuda, S., Furuno, M., Hasegawa, A., Hori, F., Ishikawa-Kato, S., Kaida, K., Kaiho, A., Kanamori-Katayama, M., Kawashima, T., Kojima, M., Kubosaki, A., Manabe, R. I., Murata, M., Nagao-Sato, S., Nakazato, K., Ninomiya, N., Nishiyori-Sueki, H., Noma, S. & 158 othersSaijyo, E., Saka, A., Sakai, M., Simon, C., Suzuki, N., Tagami, M., Watanabe, S., Yoshida, S., Arner, P., Axton, R. A., Babina, M., Kenneth Baillie, J., Barnett, T. C., Beckhouse, A. G., Blumenthal, A., Bodega, B., Bonetti, A., Briggs, J., Brombacher, F., Carlisle, A. J., Clevers, H. C., Davis, C. A., Detmar, M., Dohi, T., Edge, B. A. S., Edinger, M., Ehrlund, A., Ekwall, K., Endoh, M., Enomoto, H., Eslami, A., Fagiolini, M., Fairbairn, L., Farach-Carson, M. C., Faulkner, G. J., Ferrai, C., Fisher, M. E., Forrester, L. M., Fujita, R., Furusawa, J. I., Geijtenbeek, T. B., Gingeras, T., Goldowitz, D., Guhl, S., Guler, R., Gustincich, S., Ha, T. J., Hamaguchi, M., Hara, M., Hasegawa, Y., Herlyn, M., Heutink, P., Hitchens, K. J., Hume, D. A., Ikawa, T., Ishizu, Y., Kai, C., Kawamoto, H., Kawamura, Y. I., Kempfle, J. S., Kenna, T. J., Kere, J., Khachigian, L. M., Kitamura, T., Klein, S., Peter Klinken, S., Knox, A. J., Kojima, S., Koseki, H., Koyasu, S., Lee, W., Lennartsson, A., MacKay-Sim, A., Mejhert, N., Mizuno, Y., Morikawa, H., Morimoto, M., Moro, K., Morris, K. J., Motohashi, H., Mummery, C. L., Nakachi, Y., Nakahara, F., Nakamura, T., Nakamura, Y., Nozaki, T., Ogishima, S., Ohkura, N., Ohno, H., Ohshima, M., Okada-Hatakeyama, M., Okazaki, Y., Orlando, V., Ovchinnikov, D. A., Passier, R., Patrikakis, M., Pombo, A., Pradhan-Bhatt, S., Qin, X. Y., Rehli, M., Rizzu, P., Roy, S., Sajantila, A., Sakaguchi, S., Sato, H., Satoh, H., Savvi, S., Saxena, A., Schmidl, C., Schneider, C., Schulze-Tanzil, G. G., Schwegmann, A., Sheng, G., Shin, J. W., Sugiyama, D., Sugiyama, T., Summers, K. M., Takahashi, N., Takai, J., Tanaka, H., Tatsukawa, H., Tomoiu, A., Toyoda, H., Wetering, M., Berg, L. M. V. D., Verardo, R., Vijayan, DI., Wells, C. A., Winteringham, L. N., Wolvetang, E., Yamaguchi, Y., Yamamoto, M., Yanagi-Mizuochi, C., Yoneda, M., Yonekura, Y., Zhang, P. G., Zucchelli, S., Abugessaisa, I., Arner, E., Harshbarger, J., Kondo, A., Lassmann, T., Lizio, M., Sahin, S., Sengstag, T., Severin, J., Shimoji, H., Suzuki, M., Suzuki, H., Kawai, J., Kondo, N., Itoh, M., Daub, C. O., Kasukawa, T., Kawaji, H., Carninci, P., Forrest, A. R. R. & Hayashizaki, Y., 29 Aug 2017, In : Scientific Data. 4, 170112.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

Gene Expression Profile

Gene expression

Mouse

Transcription

Cell

13 Citations (Scopus)

67 Downloads (Pure)

Human heart disease: lessons from human pluripotent stem cell-derived cardiomyocytes

Giacomelli, E., Mummery, C. L. & Bellin, M., 1 Oct 2017, In : Cellular and Molecular Life Sciences. 74, 20, p. 3711-3739 29 p.

Research output: Contribution to journal › Review article › Academic › peer-review

Open Access

File

Pluripotent Stem Cells

Cardiac Myocytes

Heart Diseases

Cardiovascular Diseases

Research

11 Citations (Scopus)

68 Downloads (Pure)

Human Pluripotent Stem Cell Differentiation into Functional Epicardial Progenitor Cells

Guadix, J. A., Orlova, V. V., Giacomelli, E., Bellin, M., Ribeiro, M. C., Mummery, C. L., Pérez-Pomares, J. M. & Passier, R., 12 Dec 2017, In : Stem cell reports. 9, 6, p. 1754-1764 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

Pluripotent Stem Cells

Stem cells

Cell Differentiation

Stem Cells

Bone Morphogenetic Protein 4

InPulse CrackIT Challenge: Development of An In Vitro Platform Using Physiologically Mature Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Screen for Drug-Induced Effects on Cardiac Contractility

Harris, K., Rossman, E., Xu, X., Clements, P., Mannhardt, I., Hansen, A., Saleem, U., Eschenhagen, T., Hortigon, M., Rodriguez, V. Z., Smith, G., van Meer, B., Tertoolen, L., Mummery, C., Catarino Ribeiro, M., Passier, R., de Korte, T., Vlaming, M., Braam, S., Vickers, C. & 5 othersMosqueira, D., Firth, K., Prodanov, L., George, V. & Denning, C., 2017, In : Journal of Pharmacological and Toxicological Methods. 88, 2, p. 238-238 0227.

Research output: Contribution to journal › Meeting Abstract › Other research output

38 Citations (Scopus)

86 Downloads (Pure)

Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: has the time come?

Sala, L., Bellin, M. & Mummery, C. L., 1 Nov 2017, In : British journal of pharmacology. 174, 21, p. 3749-3765 17 p.

Research output: Contribution to journal › Review article › Academic › peer-review

Open Access

File

Pluripotent Stem Cells

Cardiac Myocytes

Pharmacology

Safety

Cardiac Arrhythmias

46 Citations (Scopus)

47 Downloads (Pure)

Small molecule absorption by PDMS in the context of drug response bioassays

van Meer, B. J., de Vries, H., Firth, K. S. A., van Weerd, J., Tertoolen, L. G. J., Karperien, H. B. J., Jonkheijm, P., Denning, C., IJzerman, A. P. & Mummery, C. L., 2017, In : Biochemical and biophysical research communications. 482, 2, p. 323-328 6 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

Bioassay

Lab-On-A-Chip Devices

Biological Assay

Molecules

Microfluidics

54 Citations (Scopus)

31 Downloads (Pure)

Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells

Giacomelli, E., Bellin, M., Sala, L., Van Meer, B. J., Tertoolen, L. G. J., Orlova, V. V. & Mummery, C. L., 15 Mar 2017, In : Development (Cambridge). 144, 6, p. 1008-1017 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

Pluripotent Stem Cells

Cardiac Myocytes

Endothelial Cells

Endothelium

Induced Pluripotent Stem Cells

52 Downloads (Pure)

Versatile open software to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo

Sala, L., Van Meer, B. J., Tertoolen, L. G. J., Bakkers, J., Bellin, M., Davis, R. P., Denning, C., Dieben, M. A. E., Eschenhagen, T., Giacomelli, E., Grandela, C., Hansen, A., Holman, E. R., Jongbloed, M. R. M., Kamel, S. M., Koopman, C. D., Lachaud, Q., Mannhardt, I., Mol, M. P. H., Orlova, V. V. & 6 othersPassier, R., Ribeiro, M. C., Saleem, U., Smith, G. L., Mummery, C. L. & Burton, F. L., 2017, bioRxiv.

Research output: Working paper › Professional

Open Access

File

Muscle Contraction

Cardiac Myocytes

Myocardium

Software

Heart Diseases

2 Downloads (Pure)

Z-disc protein CHAPb induces cardiomyopathy and contractile dysfunction in the postnatal heart

Van Eldik, W., Den Adel, B., Monshouwer-Kloots, J. J., Salvatori, D., Maas, S., Van Der Made, I., Creemers, E. E., Frank, D., Frey, N., Boontje, N., Van Der Velden, J., Steendijk, P., Mummery, C., Passier, R. & Beqqali, A., 1 Dec 2017, In : PLoS ONE. 12, 12, e0189139.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

cardiomyopathy

Cardiomyopathies

actin

Actins

heart

2016

20 Citations (Scopus)

39 Downloads (Pure)

A comprehensive gene expression analysis at sequential stages of in vitro cardiac differentiation from isolated MESP1-expressing-mesoderm progenitors

den Hartogh, S. C., Wolstencroft, K., Mummery, C. L. & Passier, R., 19 Jan 2016, In : Scientific reports. 6, 19386.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

Mesoderm

Gene Expression

Pluripotent Stem Cells

Neoplastic Stem Cells

Gene Regulatory Networks

218 Downloads (Pure)

Challenges of immaturity and proliferation in using hPSC-derived cardiomyocytes as disease models

Mummery, C., Birket, M., van Meer, B., Ribeiro, M., Passier, R., Bellin, M., Orlova, V., Davis, G. R., Freund, C., Kosmidis, G. & Tertoolen, L., Nov 2016, In : Human Gene Therapy. 27, 11, p. A11-A11 INV38.

Research output: Contribution to journal › Meeting Abstract › Other research output

Open Access

56 Citations (Scopus)

44 Downloads (Pure)

Complex Tissue and Disease Modeling using hiPSCs

Passier, R., Orlova, V. V. & Mummery, C., 3 Mar 2016, In : Cell stem cell. 18, 3, p. 309-321 13 p.

Research output: Contribution to journal › Review article › Academic › peer-review

Open Access

File

Pluripotent Stem Cells

Preclinical Drug Evaluations

Genetic Models

Blood Vessels

Phenotype

44 Downloads (Pure)

Go with the flow: humane stamcellen in vasculair onderzoek

Mummery, C. L., 10 Mar 2016, Enschede: Universiteit Twente. 13 p.

Research output: Book/Report › Inaugural speech › Other research output

Open Access

File

Organ-on-Chip: A synthetic mimic for human myocardium

van Meer, B., Catarino Ribeiro, M., Tertoolen, L., Birket, M. J., Passier, R. & Mummery, C., 2016, In : Journal of Pharmacological and Toxicological Methods. 81, p. 388-388 0176.

Research output: Contribution to journal › Meeting Abstract › Other research output

Organs-on-Chips in Drug Development: The Importance of Involving Stakeholders in Early Health Technology Assessment

Middelkamp, H. H. T., van der Meer, A. D., Hummel, J. M., Stamatialis, D., Mummery, C. L., Passier, P. C. J. J. & IJzerman, M. J., 19 Feb 2016, In : Applied in vitro toxicology. 2, 2, p. 74-81

Research output: Contribution to journal › Article › Academic › peer-review

Biomedical Technology Assessment

Health

Technology

Pharmaceutical Preparations

Decision Support Techniques

155 Downloads (Pure)

Stamcellen. Wetenschap, werkelijkheid en fictie

Karperien, H. B. J. & Mummery, C. L., 2016, Den Haag: Stichting Bio-Wetenschappen en Maatschappij. 84 p.

Research output: Book/Report › Book › Popular

File

30 Citations (Scopus)

45 Downloads (Pure)

Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes

Chen, Z., Xian, W., Bellin, M., Dorn, T., Tian, Q., Goedel, A., Dreizehnter, L., Schneider, C. M., Ward-van Oostwaard, D., Ng, J. K. M., Hinkel, R., Pane, L. S., Mummery, C. L., Lipp, P., Moretti, A., Laugwitz, K-L. & Sinnecker, D., 2016, In : European heart journal. 38, 4, p. 292–301

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

Induced Pluripotent Stem Cells

Drug Design

Cardiac Myocytes

Action Potentials

Romano-Ward Syndrome

21 Citations (Scopus)

11 Downloads (Pure)

TECRL, a new life-threatening inherited arrhythmia gene associated with overlapping clinical features of both LQTS and CPVT

Devalla, H. D., Gélinas, R., Aburawi, E. H., Beqqali, A., Goyette, P., Freund, C., Chaix, M. A., Tadros, R., Jiang, H., Le Béchec, A., Monshouwer-Kloots, J. J., Zwetsloot, T., Kosmidis, G., Latour, F., Alikashani, A., Hoekstra, M., Schlaepfer, J., Mummery, C. L., Stevenson, B., Kutalik, Z. & 9 othersde Vries, A. A. F., Rivard, L., Wilde, A. A. M., Talajic, M., Verkerk, A. O., Al-Gazali, L., Rioux, J. D., Bhuiyan, Z. A. & Passier, R., 1 Dec 2016, In : EMBO molecular medicine. 8, 12, p. 1390-1408 19 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

Induced Pluripotent Stem Cells

Cardiac Arrhythmias

Cardiac Myocytes

Genes

Flecainide

2015

11 Citations (Scopus)

Altered calcium handling and increased contraction force in human embryonic stem cell derived cardiomyocytes following short term dexamethasone exposure

Kosmidis, G., Bellin, M., Ribeiro, M. C., van Meer, B., Ward-van Oostwaard, D., Passier, R., Tertoolen, L. G. J., Mummery, C. L. & Casini, S., 27 Nov 2015, In : Biochemical and biophysical research communications. 467, 4, p. 998-1005 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

Stem cells

Cardiac Myocytes

Dexamethasone

Glucocorticoids

Calcium

52 Citations (Scopus)

1 Downloads (Pure)

Contractile Defect Caused by Mutation in MYBPC3 Revealed under Conditions Optimized for Human PSC-Cardiomyocyte Function

Birket, M. J., Ribeiro, M. C., Kosmidis, G., Ward, D., Leitoguinho, A. R., van de Pol, V., Dambrot, C., Devalla, H. D., Davis, R. P., Mastroberardino, P. G., Atsma, D. E., Passier, R. & Mummery, C. L., 27 Oct 2015, In : Cell reports. 13, 4, p. 733-745 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

Hypertrophic Cardiomyopathy

Stem cells

Cardiac Myocytes

Induced Pluripotent Stem Cells

Pluripotent Stem Cells

94 Citations (Scopus)

Expansion and patterning of cardiovascular progenitors derived from human pluripotent stem cells

Birket, M. J., Ribeiro, M. C., Verkerk, A. O., Ward, D., Leitoguinho, A. R., Den Hartogh, S. C., Orlova, V. V., Devalla, H. D., Schwach, V., Bellin, M., Passier, R. & Mummery, C. L., 10 Sep 2015, In : Nature biotechnology. 33, 9, p. 970-979 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

Pluripotent Stem Cells

Stem cells

Bearings (structural)

Stem Cells

Cardiac Myocytes

95 Citations (Scopus)

1 Downloads (Pure)

Functional maturation of human pluripotent stem cell derived cardiomyocytes invitro - Correlation between contraction force andelectrophysiology

Ribeiro, M. C., Tertoolen, L. G., Guadix, J. A., Bellin, M., Kosmidis, G., D'Aniello, C., Monshouwer-Kloots, J., Goumans, M. J., Wang, Y. L., Feinberg, A. W., Mummery, C. L. & Passier, R., 1 Jan 2015, In : Biomaterials. 51, p. 138-150 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

Pluripotent Stem Cells

Stem cells

Cardiac Myocytes

Electrophysiology

Membranes

234 Citations (Scopus)

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells

27 Feb 2015, In : Science. 347, 6225, p. 1010-1014 5 p.

Research output: Contribution to journal › Article › Academic › peer-review

Transcription Factors

Gene Regulatory Networks

Binding Sites

RNA

Messenger RNA

47 Citations (Scopus)

4 Downloads (Pure)

Transcriptome of human foetal heart compared with cardiomyocytes from pluripotent stem cells

Van Den Berg, C. W., Okawa, S., Chuva De Sousa Lopes, S. M., Van Iperen, L., Passier, R., Braam, S. R., Tertoolen, L. G., Del Sol, A., Davis, R. P. & Mummery, C. L., 23 Sep 2015, In : Development (Cambridge). 142, 18, p. 3231-3238 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

Fetal Heart

Pluripotent Stem Cells

Transcriptome

Cardiac Myocytes

Second Pregnancy Trimester

2010

29 Citations (Scopus)

6 Downloads (Pure)

CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function

Beqqali, A., Monshouwer-Kloots, J., Monteiro, R., Welling, M., Bakkers, J., Ehler, E., Verkleij, A., Mummery, C. & Passier, R., 1 Apr 2010, In : Journal of cell science. 123, 7, p. 1141-1150 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

Actins

Myocardium

Skeletal Muscle

Proteins

Muscle Development

50 Citations (Scopus)

5 Downloads (Pure)

Extracellular matrix formation after transplantation of human embryonic stem cell-derived cardiomyocytes

Van Laake, L. W., Van Donselaar, E. G., Monshouwer-Kloots, J., Schreurs, C., Passier, R., Humbel, B. M., Doevendans, P. A., Sonnenberg, A., Verkleij, A. J. & Mummery, C. L., 1 Jan 2010, In : Cellular and Molecular Life Sciences. 67, 2, p. 277-290 14 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

Cardiac Myocytes

Extracellular Matrix

Transplantation

Fibronectins

Integrins

26 Citations (Scopus)

19 Downloads (Pure)

Sox2 Transduction enhances cardiovascular repair capacity of blood-derived mesoangioblasts

Koyanagi, M., Iwasaki, M., Rupp, S., Tedesco, F. S., Yoon, C. H., Boeckel, J. N., Trauth, J., Schütz, C., Ohtani, K., Goetz, R., Iekushi, K., Bushoven, P., Momma, S., Mummery, C., Passier, R., Henschler, R., Akintuerk, H., Schranz, D., Urbich, C., Galvez, B. G. & 3 othersCossu, G., Zeiher, A. M. & Dimmeler, S., 1 Apr 2010, In : Circulation research. 106, 7, p. 1290-1302 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

Cell- and Tissue-Based Therapy

Cardiac Myocytes

Endothelial Cells

Myocardial Infarction

Adult Stem Cells

2007

756 Citations (Scopus)

Characterization of human embryonic stem cell lines by the International Stem Cell Initiative

1 Jan 2007, In : Nature biotechnology. 25, 7, p. 803-816 14 p.

Research output: Contribution to journal › Article › Academic › peer-review

Antigens

Stem cells

Stem Cells

Genes

Cell Line