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Research Output 2003 2019

2019
4 Downloads (Pure)

Designing Programmable Hydrogels for Controlled Vessel Formation within Engineered Tissues

Rana, D., Salehi Nik, N. & Rouwkema, J., 27 May 2019, p. 951. 1 p.

Research output: Contribution to conferenceAbstractAcademic

Open Access
File
Hydrogels
Tissue
Vascular Endothelial Growth Factor A
Endothelial cells
Intercellular Signaling Peptides and Proteins
8 Downloads (Pure)

Modification of mechanical environment to control vascular organization within developing chicken embryo

Padmanaban, P., Chizari, A., Steenbergen, W. & Rouwkema, J., 27 May 2019, p. 1259 - 1259. 1 p.

Research output: Contribution to conferenceAbstractAcademic

File
Blood Vessels
Chickens
Embryonic Structures
Egg Yolk
Organizations

Regulation of endothelial cell arrangements within hMSC – HUVEC co-cultured aggregates

Deegan, A. J., Hendrikson, W. J., El Haj, A. J., Rouwkema, J. & Yang, Y., 17 Jul 2019, In : Biomedical Journal.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Endothelial Cells
Suspensions
Bone and Bones
Transplants
Culture Techniques

Towards Controlling Vascularization within Engineered Tissues via Programmable Hydrogels

Rana, D., Salehi Nik, N. & Rouwkema, J., 28 Jun 2019, p. 27. 1 p.

Research output: Contribution to conferenceAbstractAcademic

Open Access
File
Hydrogels
Vascular Endothelial Growth Factor A
Intercellular Signaling Peptides and Proteins
Human Umbilical Vein Endothelial Cells
Mesenchymal Stromal Cells

Towards Spatiotemporally Controlled Vascular Network Formation within Engineered Tissues

Rana, D., Salehi Nik, N. & Rouwkema, J., 20 Jun 2019.

Research output: Contribution to conferencePosterAcademic

Hydrogels
Blood Vessels
Vascular Endothelial Growth Factor A
Human Umbilical Vein Endothelial Cells
Coculture Techniques

Towards Spatiotemporally Controlled Vascular Network Formation within Engineered Tissues

Rana, D., Salehi Nik, N. & Rouwkema, J., 20 Jun 2019.

Research output: Contribution to conferenceAbstractAcademic

Hydrogels
Blood Vessels
Vascular Endothelial Growth Factor A
Human Umbilical Vein Endothelial Cells
Coculture Techniques
10 Downloads (Pure)

What Controls Endothelial Sprouting? Interstitial Flow vs. Shear Stress

Salehi Nik, N., Sayedipour, S. S., Padmanaban, P., Stein, F. & Rouwkema, J., 30 May 2019, p. 1213-1213. 1 p.

Research output: Contribution to conferenceAbstractAcademic

Open Access
File
Hydrogel
Blood Vessels
Microfluidics
Endothelial Cells
Pressure
2018
249 Downloads (Pure)

Buccal fat pad as a potential source of stem cells for bone regeneration: an in vitro study

Salehi Nik, N., Ghasemi, N., Rouwkema, J. & Khojasteh, A., 7 Sep 2018, p. 613. 1 p.

Research output: Contribution to conferenceAbstractAcademic

Open Access
File
Bone Regeneration
Cheek
Adipose Tissue
Stem Cells
Bioreactors
5 Downloads (Pure)

Buccal Fat Pad as a Potential Source of Stem Cells for Bone Regeneration: an in vitro Study in Static and Dynamic Culture

Salehi Nik, N., Ghasemi, N., Rouwkema, J. & Khojasteh, A., 7 Sep 2018. 1 p.

Research output: Contribution to conferencePosterAcademic

Open Access
File
Bone Regeneration
Cheek
Adipose Tissue
Stem Cells
Bone and Bones
30 Downloads (Pure)

Characterization of cell spheroids as promising tool as 3D printable building blocks for vascular network formation

Stein, F., Trikalitis, V. W. D., Feitosa-Afonsso, D. M. & Rouwkema, J., 30 Nov 2018.

Research output: Contribution to conferencePosterAcademic

Open Access
File
Blood Vessels
Smooth Muscle Myocytes
Mesenchymal Stromal Cells
Human Umbilical Vein Endothelial Cells
Sepharose
16 Downloads (Pure)

Controlling Vascularisation Within Tissue Building Blocks Using Internal and External Mechanical Cues

Zhang, J., Padmanaban, P. & Rouwkema, J., 30 Nov 2018.

Research output: Contribution to conferencePosterAcademic

Open Access
File
Shear stress
Tissue
Geometry
Hemodynamics
Linings
1 Downloads (Pure)

Glaucoma-on-a-chip: An in vitro model for glaucoma drug discovery based on mimicking the mechanical stress of high eye pressure

Gorgels, T. G. M. F., Vroemen, P. A. M. M., Sinha, R., Rouwkema, J., Moroni, L., de Boer, J. & Webers, C. A. B., Mar 2018, In : Acta Ophthalmologica. 96, p. 19-19

Research output: Contribution to journalArticleAcademicpeer-review

25 Downloads (Pure)

Inside the box: 3D system to probe the vascular networks within developing chicken embryo

Padmanaban, P., Chizari, A., Steenbergen, W. & Rouwkema, J., 30 Nov 2018, p. 70-70. 1 p.

Research output: Contribution to conferencePosterAcademic

Open Access
File
egg shell
blood vessels
probes (equipment)
embryo (animal)
chickens
8 Citations (Scopus)

Interconnectable Dynamic Compression Bioreactors for Combinatorial Screening of Cell Mechanobiology in Three Dimensions

Seo, J., Shin, J. Y., Leijten, J., Jeon, O., Bal Öztürk, A., Rouwkema, J., Li, Y., Shin, S. R., Hajiali, H., Alsberg, E. & Khademhosseini, A., 25 Apr 2018, In : ACS applied materials & interfaces. 10, 16, p. 13293-13303 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Bioreactors
Screening
Hydrogels
Stem cells
Hydrogel
13 Downloads (Pure)

Microphysiological systems: analysis of the current status, challenges and commercial future

Ribas, J., Pawlikowsk, J. & Rouwkema, J., 1 Nov 2018, In : Microphysiological systems. 2, 10 p., 10.

Research output: Contribution to journalReview articleAcademicpeer-review

Systems analysis
Drug Discovery
1 Downloads (Pure)

Programmable Release of Vascular Endothelial Growth Factor for Vascularization in Engineered Tissues

Rana, D., Salehi Nik, N. & Rouwkema, J., 29 Nov 2018.

Research output: Contribution to conferenceAbstractAcademic

Roadmap for predicting vascular organization within engineered tissues

Padmanaban, P. & Rouwkema, J., 11 Sep 2018, p. 121-122. 2 p.

Research output: Contribution to conferenceAbstractAcademic

Tissue
Flow of fluids
Structural design
Tissue engineering
Needles
2 Citations (Scopus)
Glutaral
Carbon Dioxide
Surgery
Carbon dioxide
Mechanical properties
17 Downloads (Pure)

The role of mechanical environment in regulating vascular network formation

Stein, F., Rouwkema, J., Salehi Nik, N. & Padmanaban, P., 8 Jul 2018.

Research output: Contribution to conferencePosterAcademic

Open Access
File
Hydrogels
Hydrogel
Blood Vessels
Human Umbilical Vein Endothelial Cells
Ribose
32 Downloads (Pure)

Towards Vascularized Tissue Blocks Using a Suspension Bioprinted Blood Vessel

Trikalitis, V. D., Stein, F., Perea Paizal, J., Salehi-Nik, N. & Rouwkema, J., 6 Sep 2018.

Research output: Contribution to conferencePosterAcademic

Open Access
File
Blood Vessels
Suspensions
Bioprinting
Intercellular Signaling Peptides and Proteins
Vascular Endothelial Growth Factor A

Vascularized Tissue Blocks Using a Suspension 3D Printed Spheroid Blood Vessel

Trikalitis, V. D., Stein, F., Perea Paizal, J., Salehi Nik, N. & Rouwkema, J., 24 Jan 2018.

Research output: Contribution to conferenceAbstractAcademic

Blood Vessels
Suspensions
Bioprinting
Intercellular Signaling Peptides and Proteins
Vascular Endothelial Growth Factor A
2017
7 Citations (Scopus)

Biomechanical Strain Exacerbates Inflammation on a Progeria-on-a-Chip Model

Ribas, J., Zhang, Y. S., Pitrez, P. R., Leijten, J. C. H., Miscuglio, M., Rouwkema, J., Dokmeci, M. R., Nissan, X., Ferreira, L. & Khademhosseini, A., 17 Feb 2017, In : Small. 13, 15, 13 p., 1603737.

Research output: Contribution to journalArticleAcademicpeer-review

Progeria
Vascular Diseases
Aging of materials
Inflammation
Drug Discovery
30 Downloads (Pure)

Blood Vessel Model using Tissue Modules with on-demand Stimuli

Trikalitis, V., Salehi Nik, N. & Rouwkema, J., 28 Nov 2017.

Research output: Contribution to conferencePosterOther research output

Open Access
File
Blood Vessels
Tissue Engineering
Smooth Muscle Myocytes
Intercellular Signaling Peptides and Proteins
Fibroblasts
108 Downloads (Pure)

Building gyms for cells - development of combinatorial screening platforms for mechanical stimulation

Sinha, R., 16 Feb 2017, Enschede: Universiteit Twente. 156 p.

Research output: ThesisPhD Thesis - Research UT, graduation UTAcademic

File
Screening
Shear stress
Tissue engineering
Throughput
Substrates
74 Downloads (Pure)

Effect of fluid flow on vascular network organization in a multi-structural in vitro model

Stein, F., Trenti, C., Salehi Nik, N. & Rouwkema, J., 29 Nov 2017.

Research output: Contribution to conferencePosterAcademic

Open Access
File
Hydrogel
Blood Vessels
Human Umbilical Vein Endothelial Cells
Collagen
Vascular Endothelial Growth Factor A
23 Citations (Scopus)
45 Downloads (Pure)

Engineering Photocrosslinkable Bicomponent Hydrogel Constructs for Creating 3D Vascularized Bone

Kazemzadeh-Narbat, M., Rouwkema, J., Annabi, N., Cheng, H., Ghaderi, M., Cha, B-H., Aparnathi, M., Khalilpour, A., Byambaa, B., Jabbari, E., Tamayol, A. & Khademhosseini, A., 27 Feb 2017, In : Advanced healthcare materials. 6, 10, 1601122.

Research output: Contribution to journalArticleAcademicpeer-review

File
Hydrogel
Hydrogels
Bone
Osteogenesis
Bone and Bones
11 Citations (Scopus)
39 Downloads (Pure)

Influence of Additive Manufactured Scaffold Architecture on the Distribution of Surface Strains and Fluid Flow Shear Stresses and Expected Osteochondral Cell Differentiation

Hendrikson, W. J., Deegan, A., Yang, Y., van Blitterswijk, C., Verdonschot, N. J. J., Moroni, L. & Rouwkema, J., 10 Feb 2017, In : Frontiers in bioengineering and biotechnology. 5, 6.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

The Need to Study, Mimic, and Target Stem Cell Niches

Vishwakarma, A., Rouwkema, J., Jones, P. A. & Karp, J. M., 14 Apr 2017, Biology and Engineering of Stem Cell Niches. Vishwakarma, A. & Karp, J. M. (eds.). Elsevier, p. 3-13 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Stem Cell Niche
Stem cells
Tissue
Regeneration
Repair
7 Citations (Scopus)
44 Downloads (Pure)

The Use of Finite Element Analyses to Design and Fabricate Three-Dimensional Scaffolds for Skeletal Tissue Engineering

Hendrikson, W. J., van Blitterswijk, C., Rouwkema, J. & Moroni, L., 17 May 2017, In : Frontiers in bioengineering and biotechnology. 5, 30.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Finite Element Analysis
Tissue Engineering
Scaffolds (biology)
Tissue engineering
Scaffolds
20 Citations (Scopus)

Towards 4D Printed Scaffolds for Tissue Engineering: Exploiting 3D Shape Memory Polymers to Deliver Time-Controlled Stimulus on Cultured Cells

Hendrikson, W. J., Rouwkema, J., Clementi, F., van Blitterswijk, C., Farè, S. & Moroni, L., 2 Aug 2017, In : Biofabrication. 9, 3, 031001.

Research output: Contribution to journalArticleAcademicpeer-review

Tissue Engineering
Scaffolds (biology)
Shape memory effect
Tissue engineering
Scaffolds
5 Citations (Scopus)

Tuning Cell and Tissue Development by Combining Multiple Mechanical Signals

Sinha, R., Verdonschot, N. J. J., Koopman, H. F. J. M. & Rouwkema, J., 1 Oct 2017, In : Tissue engineering. Part B: Reviews. 23, 5, p. 494-504 10 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Tuning
Tissue
Substrates
Topography
Shear stress
3 Downloads (Pure)

Vasculogenic Hydrogel: A Potential Substrate for Growth Factor Localization in Multi-Structural Tissue Engineering

Rana, D. & Rouwkema, J., 30 Nov 2017. 1 p.

Research output: Contribution to conferenceAbstractOther research output

Open Access
File
Hydrogel
Structural design
Tissue engineering
Hydrogels
Endothelial cells
2 Downloads (Pure)
Open Access
File
Hydrogel
Tissue Engineering
Intercellular Signaling Peptides and Proteins
Endothelial Cells
Hydrogels
2016
27 Citations (Scopus)

Advancing Tissue Engineering: A Tale of Nano-, Micro-, and Macroscale Integration

Leijten, J. C. H., Rouwkema, J., Zhang, Y. S., Nasajpour, A., Dokmeci, M. R. & Khademhosseini, A., 2016, In : Small. 12, 16, p. 2130-2145 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Microtechnology
Nanotechnology
Tissue Engineering
Tissue engineering
Cellular Microenvironment
3 Citations (Scopus)
1 Downloads (Pure)

Biological and Tribological Assessment of Poly(Ethylene Oxide Terephthalate)/Poly(Butylene Terephthalate), Polycaprolactone, and Poly (L\DL) Lactic Acid Plotted Scaffolds for Skeletal Tissue Regeneration

Hendrikson, W. J., Zeng, X., Rouwkema, J., van Blitterswijk, C., van der Heide, E. & Moroni, L., 2016, In : Advanced healthcare materials. 5, 2, p. 232-243

Research output: Contribution to journalArticleAcademicpeer-review

Tissue Scaffolds
Ethylene Oxide
Tissue regeneration
Polycaprolactone
Lactic acid
12 Citations (Scopus)

Directed Assembly and Development of Material-Free Tissues with Complex Architectures

Vrij, E., Rouwkema, J., LaPointe, V., van Blitterswijk, C., Truckenmüller, R. K. & Rivron, N. C., 2016, In : Advanced materials. 28, 21, p. 4032-4039 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

22 Downloads (Pure)

Effects of varying degrees of surface strain anisotropies on endothelial cells

Sinha, R., le Gac, S., Verdonschot, N. J. J., van den Berg, A., Koopman, H. F. J. M. & Rouwkema, J., 17 May 2016, 10th World Biomaterials Congress. Montreal, Canada: Frontiers Media S.A., p. -

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Anisotropy
Endothelial Cells
Human Umbilical Vein Endothelial Cells
Equipment and Supplies
Coloring Agents
15 Citations (Scopus)
16 Downloads (Pure)

Endothelial cell alignment as a result of anisotropic strain and flow induced shear stress combinations

Sinha, R., le Gac, S., Verdonschot, N. J. J., van den Berg, A., Koopman, H. F. J. M. & Rouwkema, J., 12 Jul 2016, In : Scientific reports. 6, 12 p., 29510.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
shear stress
endothelial cells
in vitro studies
blood flow
cells
85 Citations (Scopus)

Engineering Immunomodulatory Biomaterials To Tune the Inflammatory Response

Vishwakarma, A., Bhise, N. S., Evangelista, M. B., Rouwkema, J., Dokmeci, M. R., Ghaemmaghami, A. M., Vrana, N. E. & Khademhosseini, A., 2016, In : Trends in biotechnology. 34, 6, p. 470-482 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Biocompatible Materials
Biomaterials
Immunomodulation
Tissue Engineering
Tissue engineering
17 Citations (Scopus)
17 Downloads (Pure)

Increased cell seeding efficiency in bioplotted three-dimensional PEOT/PBT scaffolds

Leferink, A. M., Hendrikson, W. J., Rouwkema, J., Karperien, H. B. J., van Blitterswijk, C. & Moroni, L., 1 Aug 2016, In : Journal of tissue engineering and regenerative medicine. 10, 8, p. 679-689 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Scaffolds
Cell Count
Biocompatible Materials
Scaffolds (biology)
Stem cells
5 Citations (Scopus)
2 Downloads (Pure)

Mold-based application of laser-induced periodic surface structures (LIPPS) on biomaterials for nanoscale patterning

Hendrikson, W. J., Masman-Bakker, W., van Bochove, B., Skolski, J. Z. P., Eichstädt, J., Koopman, H. F. J. M., van Blitterswijk, C., Grijpma, D. W., Römer, G. R. B. E., Moroni, L. & Rouwkema, J., 3 Sep 2016, In : Macromolecular bioscience. 16, 1, p. 43-49 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Biocompatible Materials
Biomaterials
Surface structure
Lasers
Fungi
72 Downloads (Pure)

Rational scaffold design for skeletal tissue engineering: a modelling and experimental approach

Hendrikson, W. J., 2 Dec 2016, Enschede: Universiteit Twente. 171 p.

Research output: ThesisPhD Thesis - Research UT, graduation UTAcademic

File
Tissue Engineering
Friction
Biocompatible Materials
Cartilage
Molecular Weight
126 Citations (Scopus)

Vascularization and Angiogenesis in Tissue Engineering: Beyond Creating Static Networks

Rouwkema, J. & Khademhosseini, A., 2016, In : Trends in biotechnology. 34, 9, p. 733-745 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Tissue Engineering
Tissue engineering
Nutrients
Blood Vessels
Tissue
2015

A Hydrogel System with Tunable Mechanical Properties to Control Mesenchymal Stromal Cell Differentiation

Rouwkema, J., Vishwakarma, A. & Khademhosseini, A., 8 Sep 2015, p. S299-S300.

Research output: Contribution to conferenceAbstractOther research output

16 Citations (Scopus)

A medium throughput device to study the effects of combinations of surface strains and fluid-flow shear stresses on cells

Sinha, R., le Gac, S., Verdonschot, N. J. J., van den Berg, A., Koopman, H. F. J. M. & Rouwkema, J., 31 Oct 2015, In : Lab on a chip. 15, 2, p. 429-439 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Shear stress
Flow of fluids
Throughput
Equipment and Supplies
Myoblasts

Gelatin Methacrylamide: Poly (Ethylene Glycol) Composite Hydrogels with Tunable Mechanical Properties to Control Mesenchymal Stromal Cell Differentiation

Rouwkema, J., Vishwakarma, A. & Khademhosseini, A., 30 Aug 2015, p. -.

Research output: Contribution to conferencePosterOther research output

11 Citations (Scopus)
23 Downloads (Pure)

Influence of PCL molecular weight on mesenchymal stromal cell differentiation

Hendrikson, W. J., Rouwkema, J., van Blitterswijk, C. & Moroni, L., 2015, In : RSC advances. 5, p. 54510-54516 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Polycaprolactone
Scaffolds
Molecular weight
Tissue engineering
Mechanical properties
7 Downloads (Pure)

Supercritical Carbon Dioxide Decellularisation of Pericardium: Mechanical and Structural Characterisation for Applications in Cardiovascular Surgery

Halfwerk, F. R., Rouwkema, J., Gossen, J. & Grandjean, J. G., Jul 2015, ISB 2015 Glasgow: XXV Congress of the International Society of Biomechanics: Abstract Book. International Society of Biomechanics, p. 2155 2157 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Open Access
File
2014