J.N. Post

dr.ing.

  • 1730 Citations
  • 14 h-Index
20012019
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Research Output 2001 2019

2013
30 Citations (Scopus)
54 Downloads (Pure)

GREM1, FRZB and DKK1 mRNA levels correlate with osteoarthritis and are regulated by osteoarthritis associated factors

Leijten, J. C. H., Bos, S. D., Landman, E., Georgi, N., Jahr, H., Meulenbelt, I., Post, J. N., van Blitterswijk, C. & Karperien, H. B. J., 19 Sep 2013, In : Arthritis research & therapy. 15, 5, p. 1-11 R126.

Research output: Contribution to journalArticleAcademicpeer-review

File
Bone Morphogenetic Proteins
Osteoarthritis
Cartilage
Bone Morphogenetic Protein 1
Articular Cartilage

Mathematical modeling of signaling pathways in osteoarthritis

Scholma, J., Kerkhofs, J., Schivo, S., Langerak, R., van der Vet, P. E., Karperien, H. B. J., van de Pol, J. C., Geris, L. & Post, J. N., 19 Apr 2013, 2013 Osteoarthritis Research Society International (OARSI) World Congress. Lohmander, S. (ed.). Amsterdam: Elsevier, p. - 1 p. (S123; vol. 21, no. Suppl.).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

36 Downloads (Pure)

MicroRNAs are prognostic markers for the chondrogenic potential of MSCs

Georgi, N., Taipaleenmaki, H., van Wijnen, A., Groen, N., Janaeczek-Portalska, K., van Blitterswijk, C., de Boer, J., Post, J. N. & Karperien, H. B. J., 2013, In : Osteoarthritis and cartilage. 21, Suppl., p. S31-S32

Research output: Contribution to journalArticleAcademicpeer-review

File

Modulation of cholesterol metabolism for better cartilage formation by influencing FGF signaling

Georgi, N., Cillero Pastor, B., Wu, L., Eijkel, G., Kiss, A., Gratton, R., WIlson, B., Heeren, R. M. A., Karperien, H. B. J. & Post, J. N., 30 Sep 2013, p. -.

Research output: Contribution to conferencePoster

69 Downloads (Pure)

Nanoparticle system for the local delivery of disease modifying osteoarthritic drugs

Periyasamy, P. C., Wennink, J. W. H., Wang, R., Karperien, H. B. J., Dijkstra, P. J. & Post, J. N., 2013, In : Osteoarthritis and cartilage. 21, Supplement, p. S303-S304

Research output: Contribution to journalArticleAcademicpeer-review

File
Nanoparticles
Pharmaceutical Preparations
Cartilage
Joints
Polyethylene glycols

Role of TCF4 in signaling crosstalk with NFκB in human chondrocytes

Zhong, L., Ma, B., Post, J. N. & Karperien, H. B. J., 2013, Unknown. p. S122-S123

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

33 Citations (Scopus)

TCF4 is a pro-catabolic and apoptotic factor in human articular chondrocytes by potentiating NF-κB signaling

Ma, B., Zhong, L., van Blitterswijk, C., Post, J. N. & Karperien, H. B. J., 19 Apr 2013, In : Journal of biological chemistry. 288, p. 17552-17558

Research output: Contribution to journalArticleAcademicpeer-review

TCF Transcription Factors
Cartilage
Chondrocytes
Joints
Matrix Metalloproteinases
30 Citations (Scopus)

WNT Signaling and Cartilage: Of Mice and Men

Ma, B., Landman, E., Miclea, R. L., Wit, J. M., Robanus-Maandag, E. C., Post, J. N. & Karperien, H. B. J., 2013, In : Calcified tissue international. 92, 5, p. 399-411 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cartilage
Articular Cartilage
Chondrocytes
Regeneration
Extracellular Matrix
2012
10 Citations (Scopus)
46 Downloads (Pure)

Fetal Mesenchymal Stromal Cells Differentiating towards Chondrocytes Acquire a Gene Expression Profile Resembling Human Growth Plate Cartilage

van Gool, S. A., Emons, J. A. M., Leijten, J. C. H., Decker, E., Sticht, C., van Houwelingen, J. C., Goeman, J. J., Kleijburg, C., Scherjon, S., Gretz, N., Wit, J. M., Rappold, G., Post, J. N. & Karperien, H. B. J., 2012, In : PLoS ONE. 7, 11, p. 1-11 11 p., e44561.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
growth plate
Growth Plate
human growth
stromal cells
chondrocytes
10 Citations (Scopus)

Modelling biological pathway dynamics with Timed Automata

Schivo, S., Scholma, J., Wanders, B., Urquidi Camacho, R. A., van der Vet, P. E., Karperien, H. B. J., Langerak, R., van de Pol, J. C. & Post, J. N., Nov 2012, 2012 IEEE 12th International Conference on Bioinformatics and Bioengineering (BIBE 2012). IEEE Computer Society, p. 447-453 7 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Crosstalk
Reaction kinetics
User interfaces
Semantics
Engines
7 Citations (Scopus)
106 Downloads (Pure)

Nanomaterials for the Local and Targeted Delivery of Osteoarthritis Drugs

Periyasamy, P. C., Leijten, J. C. H., Dijkstra, P. J., Karperien, H. B. J. & Post, J. N., 2012, In : Journal of nanomaterials. 2012, 673968, p. - 13 p., 673968.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Nanostructured materials
Cartilage
Drawing (graphics)
Pharmaceutical Preparations
Biopolymers
2011
2 Citations (Scopus)

Genome-wide screening in human growth plates during puberty in one patient suggests a role for RUNX2 in epiphyseal maturation

Emons, J., Dutilh, B. E., Decker, E., Pirzer, H., Sticht, C., Gretz, N., Rappold, G., Cameron, E. R., Neil, J. C., Stein, G. S., van Wijnen, A. J., Wit, J. M., Post, J. N. & Karperien, H. B. J., 2011, In : Journal of endocrinology. 209, 2, p. 245-254

Research output: Contribution to journalArticleAcademicpeer-review

Growth Plate
Puberty
Genome
Genes
Estrogen Receptors

Investigation of nanoparticle drug delivery systems for the inhibition of p38-MAPK signaling in osteoarthritis

Periyasamy, P. C., Karperien, H. B. J. & Post, J. N., 13 Oct 2011, p. -.

Research output: Contribution to conferencePoster

Modeling biological pathway dynamics with timed automata

Schivo, S., Scholma, J., Wanders, B., Post, J. N., Karperien, H. B. J., van der Vet, P. E., Langerak, R. & van der Pol, J. A., 2011, p. -.

Research output: Contribution to conferencePoster

Modeling biological pathway dynamics with timed automata

Schivo, S., Scholma, J., Wanders, B., Post, J. N., Karperien, H. B. J., van der Vet, P. E., Langerak, R. & v.d. Pol, J., 2011, p. -.

Research output: Contribution to conferencePoster

Signaling networks in articular cartilage

Leijten, J. C. H., Ma, B., Urquido Camacho, R., Karperien, H. B. J. & Post, J. N., 2011, p. -.

Research output: Contribution to conferencePoster

Signaling networks in articular cartilage

Leijten, J. C. H., Ma, B., Urquido Camacho, R., Karperien, H. B. J. & Post, J. N., 2011, p. -.

Research output: Contribution to conferencePoster

Trophic effects of mesenchymal stem cells increase chondrocyte proliferation and matrix formation

Wu, L., Leijten, J. C. H., Georgi, N., Post, J. N., van Blitterswijk, C. & Karperien, H. B. J., 2011, In : Tissue engineering. Part A. 17, 9-10, p. 1425-1436

Research output: Contribution to journalArticleAcademicpeer-review

Cartilage
Chondrocytes
Stem cells
Mesenchymal Stromal Cells
Coculture Techniques
2010
65 Citations (Scopus)
42 Downloads (Pure)

ERK nuclear translocation is dimerization-independent but controlled by the rate of phosphorylation

Lidke, D. S., Huang, F., Post, J. N., Rieger, B., Wilsbacher, J., Thomas, J. L., Pouyssegur, J., Jovin, T. M. & Lenormand, P., 2010, In : Journal of biological chemistry. 285, 5, p. 3092-3102

Research output: Contribution to journalArticleAcademicpeer-review

File

Optimizing islet transplantation for type 1 diabetes

Buitinga, M., Hilderink, J., Trückenmuller, R., Otto, C., van Blitterswijk, C., Post, J. N., van Apeldoorn, A. A. & Karperien, H. B. J., 31 Mar 2010.

Research output: Contribution to conferencePoster

2008
124 Citations (Scopus)
1 Downloads (Pure)

Gene transfer and protein dynamics in stem cells using single cell electroporation in a microfluidic device

Valero, A., Post, J. N., van Nieuwkasteele, J. W., ter Braak, P. M., Kruijer, W. & van den Berg, A., Jan 2008, In : Lab on a chip. 8, 1, p. 62-67 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Kinome analysis of stem cells

Koopman, H. F. J. M. (ed.), Scholma, J., Joore, J. T., Kanger, J. S. (ed.), Engbersen, J. F. J. (ed.), Post, J. N. & Kruijer, W., 20 Nov 2008, p. 67-69.

Research output: Contribution to conferencePaper

3 Citations (Scopus)

Stem cells

Jukes, J., Both, S., Post, J., van Blitterswijk, C., Karperien, M. & de Boer, J., 2008, Tissue Engineering. van Blitterswijk, C. A. (ed.). Londen: Academic Press, p. 1–26

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Adult Stem Cells
Embryonic Stem Cells
Stem Cells
Blastocyst Inner Cell Mass
Embryonic and Fetal Development

The role of UTF1 in pluripotent stem cells

Koopman, H. F. J. M. (ed.), Telgenkamp, M. G., Bömer, N., Kanger, J. S. (ed.), Engbersen, J. F. J. (ed.), van der Zwan, A. G. M., Drost, A., Post, J. N. & Kruijer, W., 20 Nov 2008, p. 75-77.

Research output: Contribution to conferencePaper

2007

Repression of TGF-beta and BMP signaling pathways by UTF1 in stem cells

Telgenkamp, M. G., Drost, A., van der Zwan, A. G. M., Post, J. N. & Kruijer, W., 13 Dec 2007, p. -.

Research output: Contribution to conferencePoster

101 Citations (Scopus)
79 Downloads (Pure)

Synthesis and bioconjugation of gold nanoparticles as potential molecular probes for light-based imaging techniques

Rayavarapu, R. G., Petersen, W., Ungureanu, C., Post, J. N., van Leeuwen, T. & Manohar, S., 2007, In : International Journal of Biomedical Imaging. p. 29817-1-29817-10 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

File
2006
2 Citations (Scopus)

Gene transfer and characterization of protein dynamcis in stem cells using single cell electroporation in a microfluidic device

Valero, A., Post, J. N., Van Nieuwkasteele, J. W., Kruijer, W., Andersson, H. & Van Den Berg, A., 1 Jan 2006, p. 22-24. 3 p.

Research output: Contribution to conferencePaper

Gene transfer
Stem cells
Microfluidics
Genes
Proteins

Gene transfer and characterization of protein dynamics in stem cells using single cell electroporation in a microfluidic device

Valero, A., Post, J. N., van Nieuwkasteele, J. W., Kruijer, W., Andersson, H. & van den Berg, A., Nov 2006, Proceedings of microTAS 2006 Conference. Kitamori, T., Fujita, H. & Hasebe, S. (eds.). Tokyo, Japan: Japan Academic Association Inc, p. 22-24 3 p. (Micro Total Analysis Systems; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Regulation of self-renewal in stem cells bij TGFbeta and UTF1

Meddens, M. B. M., Post, J. N. & Kruijer, W., 2006, Enschede: Polymer Chemistry and Biomaterials (PBM). 33 p.

Research output: Book/ReportReportProfessional

Regulation of self-renewal in stem cells by BMP and UTF1

Kemna, E., Post, J. N. & Kruijer, W., 2006, Enschede: Polymer Chemistry and Biomaterials (PBM). 32 p.

Research output: Book/ReportReportProfessional

Stem cell niche signalling

Kruijer, W., Koers, A. & Post, J. N., 14 Dec 2006, p. -.

Research output: Contribution to conferencePoster

The effect of Hsp70 RNA silencing on heat-induced apoptosis

Steg, H., Hengeveld, M. R., Vermes, I., Nijhuis, E. H. A., Poot, A. A. & Post, J. N., 2006, Enschede: Polymer Chemistry and Biomaterials (PBM). 28 p.

Research output: Book/ReportReportProfessional

The role of a stem cell specific transcriptional co-activator in stem cell

Post, J. N. & Kruijer, W., 14 Dec 2006, p. -.

Research output: Contribution to conferencePoster

The role of a stem cell specific transcription factor in pluripotency and self-renewal

Post, J. N. & Kruijer, W., 14 Dec 2006, p. -.

Research output: Contribution to conferencePoster

Towards analysing UTF-1 expression in stem cells

Bongers, M., Kruijer, W. & Post, J. N., 2006, Enschede: Polymer Chemistry and Biomaterials (PBM).

Research output: Book/ReportReportProfessional

2005

Chromatin remodeling during stem cell differentiation

de Boer, F., Kruijer, W. & Post, J. N., 2005, Enschede: Werkeenheid Polymeerchemie en Biomaterialen.

Research output: Book/ReportReportProfessional

Developmentally regulated cytoplasmic retention of the transcription factor XMI-ER1 requires sequence in the acidic activation domain

Post, J. N., Luchman, H. A., Mercer, F. C., Paterno, G. D. & Gillespie, L. L., 2005, In : International journal of biochemistry & cell biology. 37, 2, p. 463-477

Research output: Contribution to journalArticleAcademic

Efficiente cel transfectie met microchip electroporatie

Bömer, N., Post, J. N., Lüttge, R. & Kruijer, W., 2005, Enschede: Werkeenheid Polymeerchemie en Biomaterialen. 41 p.

Research output: Book/ReportReportProfessional

2 Citations (Scopus)

Novel (Bio)chemical and (Photo)physical probes for imaging living cells

Jares-Erijman, E. A., Spagnuolo, C., Giordano, L., Etchehon, M., Kawior, J., Mañalich-Arana, M. V., Bossi, M., Lidke, D. S., Post, J. N., Vermeij, R. J., Heintzmann, R., Lidke, K. A., Arndt-Jovin, D. J. & Jovin, T. M., 1 Dec 2005, Supramolecular Structure and Function 8. Springer, p. 99-118 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Cells
Receptor Protein-Tyrosine Kinases
Imaging techniques
Tumors
Cytology

Novel Single Cell Fluorescence Approaches in the Investigation of Signaling at the Cellular Level

Nagy, P., Vereb, G., Post, J. N., Friedlander, E. & Szollosi, J., 2005, Biophysical aspects of transmembrane signaling. Damjanovich, S. (ed.). Springer, p. 33-70 321 p. (Springer series in biophysics; vol. 8).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

64 Citations (Scopus)

One- and two-photon photoactivation of a paGFP-fusion protein in live Drosophila embryos

Post, J. N., Lidke, K. A., Rieger, B. & Arndt-Jovin, D. J., 2005, In : FEBS letters. 579, 2, p. 325-330

Research output: Contribution to journalArticleAcademic

Regulation of BMP/TGFß response in mysenchymal stem cells

van de Wetering, G., Post, J. N., Poot, A. A. & Kruijer, W., 2005, Enschede: Werkeenheid Polymeerchemie en Biomaterialen. 23 p.

Research output: Book/ReportReportProfessional

TGFß/BMP signalling in stem cells is influenced by UTF-1

van den Hoek, F. L., Post, J. N., Bennink, M. L. & Kruijer, W., 2005, Enschede: Werkeenheid Polymeerchemie en Biomaterialen. 40 p.

Research output: Book/ReportReportProfessional

The effect of TGFbeta of endothelial progenitor cells in diabetes mellitus

Wester, M., Kruijer, W. & Post, J. N., 7 Oct 2005, Enschede: Werkeenheid Polymeerchemie en Biomaterialen. 27 p.

Research output: Book/ReportReportProfessional

2004
8 Citations (Scopus)

Dynamic and static fluorescence anisotropy in biological microscopy (rFLIM and emFRET)

Jovin, T. M., Lidke, D. S. & Post, J. N., 2004, In : Progress in Biomedical Optics and Imaging. 5323, p. 1-12

Research output: Contribution to journalArticleAcademic

706 Citations (Scopus)

Quantum dot ligands provide new insights into erbB/HER receptor–mediated signal transduction

Lidke, D. S., Nagy, P., Heintzmann, R., Arndt-Jovin, D. J., Post, J. N., Grecco, H. E., Jares-Erijman, E. A. & Jovin, T. M., 2004, In : Nature biotechnology. 22, p. 198-203

Research output: Contribution to journalArticleAcademic