• 398 Citations
  • 12 h-Index
20112019
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Research Output 2011 2019

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Article
2019
1 Citation (Scopus)
3 Downloads (Pure)

3D-Bioprinted Mini-Brain: A Glioblastoma Model to Study Cellular Interactions and Therapeutics

Heinrich, M. A., Bansal, R., Lammers, T., Zhang, Y. S., Michel Schiffelers, R. & Prakash, J., 5 Apr 2019, In : Advanced materials. 31, 14, 1806590.

Research output: Contribution to journalArticleAcademicpeer-review

Macrophages
Brain
Tumors
Chemotherapy
Crosstalk
6 Downloads (Pure)

Engineered Relaxin as theranostic nanomedicine to diagnose and ameliorate liver cirrhosis

Nagórniewicz, B., Mardhian, D. F., Booijink, R., Storm, G., Prakash, J. & Bansal, R., 1 Apr 2019, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 17, p. 106-118 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Relaxin
Medical nanotechnology
Liver Cirrhosis
Liver
Hepatic Stellate Cells
2018
9 Citations (Scopus)
104 Downloads (Pure)
Open Access
File
Catenins
Hepatic Stellate Cells
Wnt Signaling Pathway
Liver Cirrhosis
Macrophages
6 Citations (Scopus)
2 Downloads (Pure)

Nano-targeted relaxin impairs fibrosis and tumor growth in pancreatic cancer and improves the efficacy of gemcitabine in vivo

Mardhian, D. F., Storm, G., Bansal, R. & Prakash, J., 28 Nov 2018, In : Journal of controlled release. 290, p. 1-10 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
gemcitabine
Relaxin
Pancreatic Neoplasms
Fibrosis
Pancreatic Stellate Cells
8 Citations (Scopus)
209 Downloads (Pure)

Targeting the Stat6 pathway in tumor-associated macrophages reduces tumor growth and metastatic niche formation in breast cancer

Binnemars-Postma, K., Bansal, R., Storm, G. & Prakash, J., Feb 2018, In : FASEB journal. 32, 2, p. 969-978 10 p., fj.201700629R.

Research output: Contribution to journalArticleAcademicpeer-review

File
STAT6 Transcription Factor
Macrophages
Tumors
Breast Neoplasms
Growth
1 Citation (Scopus)
8 Downloads (Pure)

Therapeutic inhibition of spleen tyrosine kinase in inflammatory macrophages using PLGA nanoparticles for the treatment of non-alcoholic steatohepatitis

Kurniawan, D. W., Jajoriya, A. K., Dhawan, G., Mishra, D., Argemi, J., Bataller, R., Storm, G., Mishra, D. P., Prakash, J. & Bansal, R., 28 Oct 2018, In : Journal of controlled release. 288, p. 227-238 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Fatty Liver
Nanoparticles
Macrophages
Therapeutics
Fibrosis
2017
21 Citations (Scopus)
82 Downloads (Pure)

Drug targeting to myofibroblasts: Implications for fibrosis and cancer

Yazdani, S., Bansal, R. & Prakash, J., 1 Nov 2017, In : Advanced drug delivery reviews. 121, p. 101-116

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Myofibroblasts
Drug Delivery Systems
Fibrosis
Neoplasms
Neoplasm Metastasis
4 Citations (Scopus)
28 Downloads (Pure)

Integrin alpha 11 in the regulation of the myofibroblast phenotype: implications for fibrotic diseases

Bansal, R., Nakagawa, S., Yazdani, S., van Baarlen, J., Venkatesh, A., Koh, A. P., Song, W., Goossens, N., Watanabe, H., Beasley, M. B., Powell, C. A., Storm, G., Kaminski, N., van Goor, H., Friedman, S. L., Hoshida, Y. & Prakash, J., Nov 2017, In : Experimental and Molecular Medicine. 49, 11, p. e396 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Integrin alpha Chains
Myofibroblasts
Phenotype
Liver
Hedgehogs
15 Citations (Scopus)
39 Downloads (Pure)

Tyrosine kinase inhibitor BIBF1120 ameliorates inflammation, angiogenesis and fibrosis in CCl4-induced liver fibrogenesis mouse model

Öztürk Akcora, B., Storm, G., Prakash, J. & Bansal, R., 2017, In : Scientific reports. 7, 44545.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Protein-Tyrosine Kinases
Fibrosis
Inflammation
Liver
Hepatic Stellate Cells
2016
26 Citations (Scopus)
385 Downloads (Pure)

Clinical Advancements in the Targeted Therapies against Liver Fibrosis

Bansal, R., Nagorniewicz, B. P. & Prakash, J., 2016, In : Mediators of inflammation. 2016, 7629724, p. - 16 p., 7629724.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
6 Citations (Scopus)
27 Downloads (Pure)

Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice

Poosti, F., Bansal, R., Yazdani, S., Prakash, J., Beljaars, L., van den Born, J., de Borst, M. H., van Goor, H., Hillebrands, J-L. & Poelstra, K., 2016, In : Oncotarget. 7, 34, p. 54240-54252

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Peptidomimetics
Ureteral Obstruction
Myofibroblasts
Ureter
Interferon-gamma
11 Citations (Scopus)
38 Downloads (Pure)

Preclinical detection of liver fibrosis using dual-modality photoacoustic/ultrasound system

van den Berg, P. J., Bansal, R., Daoudi, K., Steenbergen, W. & Prakash, J., 2016, In : Biomedical optics express. 7, 12, p. 5081-5091

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
fibrosis
liver
Liver Cirrhosis
Liver
angiogenesis
2015
6 Downloads (Pure)

A new role for CD4+CD25+ regulatory T cells in promoting development of fibrosis in HCV nonstructural 3/4A transgenic mice

Bansal, R., Frelin, L. & Sällberg, M., 2015, In : Journal of viral hepatitis. 22, Suppl. S3, p. - P24.

Research output: Contribution to journalArticleAcademicpeer-review

File
31 Citations (Scopus)
91 Downloads (Pure)

Complete regression of breast tumour with a single dose of docetaxel-entrapped core-cross-linked polymeric micelles

Hu, Q., Rijcken, C. J., Bansal, R., Hennink, W. E., Storm, G. & Prakash, J., 2015, In : Biomaterials. 53, p. 370-378

Research output: Contribution to journalArticleAcademicpeer-review

File
3 Citations (Scopus)
22 Downloads (Pure)

Hepatitis C Virus Nonstructural 3/4A Protein Dampens Inflammation and Contributes to Slow Fibrosis Progression during Chronic Fibrosis In Vivo

Bansal, R., Frelin, L., Brenndörfer, E. D., Storm, G., Prakash, J. & Sällberg, M., 2015, In : PLoS ONE. 10, 6, p. e0128466- e0128466.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Hepatitis C virus
fibrosis
Viruses
Hepacivirus
Liver
1 Citation (Scopus)

Prospects and progress of DNA vaccines for treating hepatitis B

Chen, M., Jagya, N., Bansal, R., Frelin, L. & Sällberg, M., 12 Dec 2015, In : Expert review of vaccines. 15, 5, p. 629-640

Research output: Contribution to journalArticleAcademicpeer-review

DNA Vaccines
Hepatitis B
Hepatitis B virus
Chronic Hepatitis B
Therapeutics
28 Citations (Scopus)

Selective delivery of IFN-γ to renal interstitial myofibroblasts: a novel strategy for the treatment of renal fibrosis

Poosti, F., Bansal, R., Yazdani, S., Prakash, J., Post, E., Klok, P., van den Born, J., de Borst, M. H., van Goor, H., Poelstra, K. & Hillebrands, J-L., 2 Dec 2015, In : FASEB journal. 29, 3, p. 1029-1042

Research output: Contribution to journalArticleAcademicpeer-review

Myofibroblasts
Platelet-Derived Growth Factor Receptors
Fibrosis
Kidney
Ureteral Obstruction
1 Downloads (Pure)
Open Access
File
Liver Cirrhosis
Liver Diseases
Liver
Research
25 Citations (Scopus)
76 Downloads (Pure)

The interplay of the Notch signaling in hepatic stellate cells and macrophages determines the fate of liver fibrogenesis

Bansal, R., van Baarlen, J., Storm, G. & Prakash, J., 2015, In : Scientific reports. 5, 18272, 18272.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Hepatic Stellate Cells
Macrophages
Liver
Liver Cirrhosis
Fibroblasts
2014
11 Downloads (Pure)

Hepatitis C nonstructural protein 3/4a dampens inflammation and contributes to slow fibrosis progression during chronic liver injury in mice

Bansal, R., Frelin, L., Brenndorfer, E. D., Storm, G., Prakash, J. & Sallberg, M., 2014, In : Journal of hepatology. 60, Suppl. 1, p. S138-S138

Research output: Contribution to journalArticleAcademicpeer-review

File
23 Citations (Scopus)

Interferon gamma peptidomimetic targeted to hepatic stellate cells ameliorates acute and chronic liver fibrosis in vivo

Bansal, R., Prakash, J., de Ruiter, M. & Poelstra, K., 2014, In : Journal of controlled release. 179, p. 18-24

Research output: Contribution to journalArticleAcademicpeer-review

Peptidomimetics
Hepatic Stellate Cells
Liver Cirrhosis
Interferon-gamma
Platelet-Derived Growth Factor beta Receptor
13 Citations (Scopus)
25 Downloads (Pure)

Targeted Recombinant Fusion Proteins of IFNγ and Mimetic IFNγ with PDGFβR Bicyclic Peptide Inhibits Liver Fibrogenesis In Vivo

Bansal, R., Prakash, J., de Ruiter, M. & Poelstra, K., 2014, In : PLoS ONE. 9, 2, p. - e89878.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
recombinant fusion proteins
Recombinant Fusion Proteins
Platelet-Derived Growth Factor beta Receptor
interferon-gamma
Liver
2012
27 Citations (Scopus)

Selective Targeting of Interferon γ to Stromal Fibroblasts and Pericytes as a Novel Therapeutic Approach to Inhibit Angiogenesis and Tumor Growth

Bansal, R., Tomar, T., Poelstra, K. & Prakash, J., 29 Aug 2012, In : Molecular cancer therapeutics. 11, 11, p. 2419-2428

Research output: Contribution to journalArticleAcademicpeer-review

Pericytes
Interferons
Fibroblasts
Growth
Neoplasms
2011
38 Citations (Scopus)

PEGylation improves pharmacokinetic profile, liver uptake and efficacy of Interferon gamma in liver fibrosis

Bansal, R., Post, E., Proost, J. H., De Jager-Krikken, A., Poelstra, K. & Prakash, J., 25 Sep 2011, In : Journal of controlled release. 154, 3, p. 233-240 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Liver Cirrhosis
Interferon-gamma
Pharmacokinetics
Liver
Therapeutic Uses
34 Citations (Scopus)

Peptide-modified albumin carrier explored as a novel strategy for a cell-specific delivery of interferon gamma to treat liver fibrosis

Bansal, R., Prakash, J., Ruijter, M. D., Beljaars, L. & Poelstra, K., 3 Oct 2011, In : Molecular pharmaceutics. 8, 5, p. 1899-1909 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Liver Cirrhosis
Interferon-gamma
Albumins
Hepatic Stellate Cells
Peptides