R.B.M. Schasfoort

dr.ir.

  • 3048 Citations
  • 24 h-Index
1989 …2018
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Research Output 1989 2018

2018
1 Citation (Scopus)
2 Downloads (Pure)

Nanoparticle Enhancement Cascade for Sensitive Multiplex Measurements of Biomarkers in Complex Fluids with Surface Plasmon Resonance Imaging

Hendriks, J., Stojanovic, I., Schasfoort, R. B. M., Saris, D. B. F. & Karperien, M., 5 Jun 2018, In : Analytical chemistry. 90, 11, p. 6563-6571 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Surface plasmon resonance
Biomarkers
Nanoparticles
Imaging techniques
Fluids
3 Citations (Scopus)

Spermine induced reversible collapse of deoxyribonucleic acid-bridged nanoparticle-based assemblies

Göeken, K. L., Schasfoort, R. B. M., Subramaniam, V. & Gill, R., 1 Jan 2018, In : Nano research. 11, 1, p. 383-396 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Spermine
DNA
Nanoparticles
Surface plasmon resonance
Geometry
3 Citations (Scopus)
5 Downloads (Pure)

Trends in SPR Cytometry: Advances in Label-Free Detection of Cell Parameters

Schasfoort, R. B. M., Abali, F., Stojanovic, I., Vidarsson, G. & Terstappen, L., 30 Oct 2018, In : Biosensors (Switserland). 8, 4, 11 p., 102.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
File
Surface Plasmon Resonance
Surface plasmon resonance
Labels
Cells
Imaging techniques
2017
7 Citations (Scopus)
53 Downloads (Pure)

Isolation of single cells for protein therapeutics using microwell selection and Surface Plasmon Resonance imaging

Abali, F., Stevens, M., Tibbe, A. G. J., Terstappen, L. W. M. M., van der Velde, P. N. & Schasfoort, R. B. M., 15 Aug 2017, In : Analytical biochemistry. 531, p. 45-47 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Surface Plasmon Resonance
Surface plasmon resonance
Imaging techniques
Punching
Sorting
6 Citations (Scopus)

Surface plasmon resonance is an analytically sensitive method for antigen profiling of extracellular vesicles

Gool, E. L., Stojanovic, I., Schasfoort, R. B. M., Sturk, A., Van Leeuwen, T. G., Nieuwland, R., Terstappen, L. W. M. M. & Coumans, F. A. W., 1 Oct 2017, In : Clinical chemistry. 63, 10, p. 1633-1641 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Surface Plasmon Resonance
Surface plasmon resonance
Antigens
Imaging techniques
Flow cytometry
2016
4 Citations (Scopus)
45 Downloads (Pure)

Detection of apoptosis in cancer cell lines using Surface Plasmon Resonance imaging

Stojanović, I., van Hal, Y., van der Velden, T. J. G., Schasfoort, R. B. M. & Terstappen, L. W. M. M., 6 Jan 2016, In : Sensing and bio-sensing research. 7, p. 48-54

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Surface Plasmon Resonance
Surface plasmon resonance
Cell death
Cytochromes
Cells
10 Citations (Scopus)

Interpolation method for accurate affinity ranking of arrayed ligand analyte interactions

Schasfoort, R. B. M., Andree, K. C., van der Velde, N., van der Kooi, A., Stojanovic, I. & Terstappen, L. W. M. M., 13 Feb 2016, In : Analytical biochemistry. 500, p. 21-23

Research output: Contribution to journalArticleAcademicpeer-review

Interpolation
Ligands
Surface Plasmon Resonance
Equilibrium constants
Surface plasmon resonance
3 Citations (Scopus)

Modeling single cell antibody excretion on a biosensor

Stojanovic, I., Baumgartner, W., van der Velden, T. J. G., Terstappen, L. W. M. M. & Schasfoort, R. B. M., 31 Mar 2016, In : Analytical biochemistry. 504, p. 1-3

Research output: Contribution to journalArticleAcademicpeer-review

Biosensing Techniques
Biosensors
Surface Plasmon Resonance
Surface plasmon resonance
Antibodies
2 Citations (Scopus)

Scaffolding of cystine-stabilized miniproteins

Sankaran, S., Stojanovic, I., Barendregt, A., Heck, A. J. R., Schasfoort, R. B. M. & Jonkheijm, P., 2016, In : ChemistrySelect. 1, 5, p. 1039-1046 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cystine
Trypsin
Trypsin Inhibitors
Vascular Endothelial Growth Factor A
Assays
2015
30 Citations (Scopus)

C-reactive protein enhances IgG-mediated phagocyte responses and thrombocytopenia

Kapur, R., Heitink-Pollé, K. M. J., Porcelijn, L., Bentlange, A. E. H., Bruin, M. C. A., Visser, R., Roos, D., Schasfoort, R. B. M., Vidarsson, G., de Haas, M. & van der Schoot, C. E., 2015, In : Blood. 125, 11, p. 1793-1802

Research output: Contribution to journalArticleAcademicpeer-review

Phagocytes
Platelets
Thrombocytopenia
C-Reactive Protein
Immunoglobulin G
8 Citations (Scopus)

Label-Free Glycoprofiling with Multiplex Surface Plasmon Resonance: A Tool To Quantify Sialylation of Erythropoietin.

Geuijen, K. P. M., Halim, L. A., Schellekens, H., Schasfoort, R. B. M., Wijffels, R. H. & Eppink, M. H. M., 2015, In : Analytical chemistry. 87, 16, p. 8115-8122

Research output: Contribution to journalArticleAcademicpeer-review

METHODS AND MEANS FOR DETECTING CELLS USING SURFACE PLASMON RESONANCE

Vidarsson, G. & Schasfoort, R. B. M., 2015, (Submitted) Patent No. US Pat20,150,323,525

Research output: PatentProfessional

12 Citations (Scopus)

Platinum(II) as bifunctional linker in antibody-drug conjugate formation: Coupling of a 4-nitrobenzo-2-oxa-1,3-diazole fluorophore to trastuzumab as a model.

Waalboer, D. C. J., Muns, J. A., Sijbrandi, N. J., Schasfoort, R. B. M., Haselberg, R., Somsen, G. W., Houthoff, H. J. & van Dongen, G. A. M. S., 2015, In : ChemMedChem. 10, 5, p. 797-803

Research output: Contribution to journalArticleAcademicpeer-review

17 Citations (Scopus)
4 Downloads (Pure)

Quantification of antibody production of individual hybridoma cells by Surface Plasmon Resonance imaging.

Stojanovic, I., van der Velden, T. J. G., Mulder, H. W., Schasfoort, R. B. M. & Terstappen, L. W. M. M., 2015, In : Analytical biochemistry. 485, p. 112-118

Research output: Contribution to journalArticleAcademicpeer-review

Surface Plasmon Resonance
Hybridomas
Surface plasmon resonance
Antibody Formation
Imaging techniques
2014
3 Citations (Scopus)

High-throughput and multiplexed regeneration buffer scouting for affinity-based interactions

Geuijen, K. P. M., Schasfoort, R. B. M., Wijffels, R. H. & Eppink, M. H. M., 2014, In : Analytical biochemistry. 454, p. 38-40

Research output: Contribution to journalArticleAcademicpeer-review

Regeneration
Buffers
Throughput
Ligands
Biosensors
2013
41 Citations (Scopus)

Analysis of cell surface antigens by Surface Plasmon Resonance imaging

Stojanovic, I., Schasfoort, R. B. M. & Terstappen, L. W. M. M., 11 Apr 2013, In : Biosensors and bioelectronics. 52, p. 36-43

Research output: Contribution to journalArticleAcademicpeer-review

Surface Plasmon Resonance
Surface plasmon resonance
Surface Antigens
Antigens
Image sensors

It’s all about the epitope

Schasfoort, R. B. M., 12 Nov 2013, p. -.

Research output: Contribution to conferencePosterOther research output

Label-free cell profiling

Schasfoort, R. B. M., Bentlage, A. E. H., Stojanovic, I., van der Kooi, A., van der Schoot, E., Terstappen, L. W. M. M. & Vidarsson, G., 2013, In : Analytical biochemistry. 439, 1, p. 4-6

Research output: Contribution to journalArticleAcademicpeer-review

Labels
Blood
Erythrocytes
Surface Plasmon Resonance
Sensors
14 Citations (Scopus)

Label-free cell profiling

Schasfoort, R. B. M., Bentlage, A. E. H., Stojanovic, I., van der Kooi, A., van der Schoot, E., Terstappen, L. W. M. M. & Vidarsson, G., 2 Jun 2013.

Research output: Contribution to conferencePosterOther research output

Ranking the affinity

Schasfoort, R. B. M., 12 Nov 2013, p. -.

Research output: Contribution to conferencePosterOther research output

2012
9 Citations (Scopus)

Method for estimating the single molecular affinity

Schasfoort, R. B. M., de Lau, W., van der Kooi, A., Clevers, H. & Engbers, G. H. M., 2012, In : Analytical biochemistry. 421, 2, p. 794-796

Research output: Contribution to journalArticleAcademicpeer-review

Ligands
Equilibrium constants
Surface plasmon resonance
Biosensors
Labels
2011
677 Citations (Scopus)

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

de Lau, W., Barker, N., Low, T. Y., Koo, B-K., Li, V. S. W., Teunissen, H., Kujala, P., Haegebarth, A., Peters, P. J. M., van de Wetering, M., Stange, D. E., Es, J. E., Guardavaccaro, D., Schasfoort, R. B. M., Mohri, Y., Nishimori, K., Mohammed, S., Heck, A. J. R. & Clevers, H., 2011, In : Nature. 476, 7360, p. 293-297

Research output: Contribution to journalArticleAcademicpeer-review

Wnt Receptors
Wnt Signaling Pathway
Adult Stem Cells
HEK293 Cells
Gene Deletion
2010
34 Citations (Scopus)

Electrokinetic label-free screening chip: a marriage of multiplexing and high throughput analysis using surface plasmon resonance imaging

Krishnamoorthy, G., Carlen, E., Bomer, J. G., Wijnperle, D., de Boer, H. L., van den Berg, A. & Schasfoort, R. B. M., 2010, In : Lab on a chip. 10, 8, p. 986-990 5 p., 10.1039/c000705f.

Research output: Contribution to journalArticleAcademicpeer-review

23 Citations (Scopus)

Electrokinetic Lab-on-a-BioChip for Multi-ligand/Multi-analyte Biosensing

Krishnamoorthy, G., Carlen, E., de Boer, H. L., van den Berg, A. & Schasfoort, R. B. M., 15 May 2010, In : Analytical chemistry. 82, 10, p. 4145-4150 6 p., 10.1021/ac1003163.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)
2 Downloads (Pure)

Integrated electrokinetic Lab-on-a-chip based biosensor- a tool for drug screening applications

Krishnamoorthy, G., Carlen, E. T., Schasfoort, R. B. M. & van den Berg, A., 3 Oct 2010, 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010. Verpoorte, S., Andersson-Svahn, H., Emnéus, J. & Pamme, N. (eds.). San Diego: Chemical and Biological Micro Systems Society, p. 581-583 3 p. (International Conference on Miniaterized Systems for Chemistry and Life Sciences : [proceedings]; vol. 2010).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Open Access
File
Lab-on-a-chip
Biosensors
Screening
Kinetics
Surface plasmon resonance
66 Downloads (Pure)

Lab-on-a-Chip Surface Plasmon Resonance Biosensor for Multiplex Bioassays

Krishnamoorthy, G., 12 Mar 2010, Enschede: University of Twente. 192 p.

Research output: ThesisPhD Thesis - Research UT, graduation UTAcademic

File
32 Citations (Scopus)
27 Downloads (Pure)

Mapping of citrullinated fibrinogen B-cell epitopes in rheumatoid arthritis by imaging surface plasmon resonance

van Beers, J. J. B. C., Raijmakers, R., Alexander, L-E., Stammen-Vogelzangs, J., Lokate, A. M. C., Heck, A. J. R., Schasfoort, R. B. M. & Pruijn, G. J. M., 2010, In : Arthritis research & therapy. 12, 6, p. - 10 p., R219.

Research output: Contribution to journalArticleAcademicpeer-review

File
B-Lymphocyte Epitopes
Surface Plasmon Resonance
Fibrinogen
Rheumatoid Arthritis
Peptides
15 Citations (Scopus)

Surface plasmon resonance imaging based multiplex biosensor: Integration of biomolecular screening, detection and kinetics estimation.

Krishnamoorthy, G., Carlen, E., van den Berg, A. & Schasfoort, R. B. M., 15 Jul 2010, In : Sensors and actuators. B: Chemical. 148, 2, p. 511-521 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

2009

Integrated electrokinetic sample focusing and surface plasmon resonance imaging system for measuring biomolecular interactions

Krishnamoorthy, G., Carlen, E., Kohlheyer, D., Schasfoort, R. B. M. & van den Berg, A., 2009, In : Analytical chemistry. 81, 5, p. 1957-1963

Research output: Contribution to journalArticleAcademicpeer-review

22 Citations (Scopus)

Integrated Electrokinetic Sample Focusing and Surface Plasmon Resonance Imaging System for Measuring Biomolecular Interactions

Krishnamoorthy, G., Carlen, E., Kohlheyer, D., Schasfoort, R. B. M. & van den Berg, A., 1 Mar 2009, In : Analytical chemistry. 81, 5, p. 1957-1963 7 p., 10.1021/ac802668z.

Research output: Contribution to journalArticleAcademicpeer-review

90 Downloads (Pure)

Label-free biomolecular interaction sensing on microarrays using surface plasmon resonance imaging

Beusink, J. B., 26 Feb 2009, Zutphen: Wohrman Print Service. 132 p.

Research output: ThesisPhD Thesis - Research UT, graduation UTAcademic

File
Surface plasmon resonance
Microarrays
Labels
Imaging techniques
Ligands
10 Citations (Scopus)

Single injection microarray-based biosensor kinetics

Krishnamoorthy, G., Carlen, E., Beusink, J. B., Schasfoort, R. B. M. & van den Berg, A., 2009, In : Analytical methods. 1, 3, p. 162-169

Research output: Contribution to journalArticleAcademicpeer-review

Microarrays
Biosensors
Immunoglobulin G
Ligands
Kinetics
2008
13 Citations (Scopus)
24 Downloads (Pure)

A microfluidic device for array patterning by perpendicular electrokinetic focusing

Kohlheyer, D., Unnikrishnan, S., Besselink, G. A. J., Schlautmann, S. & Schasfoort, R. B. M., Jun 2008, In : Microfluidics and nanofluidics. 4, Paper P-NS/6, p. 557-564 8 p., 10.1007/s10404-007-0217-9.

Research output: Contribution to journalArticleAcademicpeer-review

File
55 Citations (Scopus)

Bubble-Free Operation of a Microfluidic Free-Flow Electrophoresis Chip with Integrated Pt Electrodes

Kohlheyer, D., Eijkel, J. C. T., Schlautmann, S., van den Berg, A. & Schasfoort, R. B. M., 1 Jun 2008, In : Analytical chemistry. 80, 11, p. 4111-4118 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

55 Downloads (Pure)

Electrokinetic Methods for Preparative Electrophoresis on a Chip

Zalewski, D. R., 24 Oct 2008, Enschede: University of Twente. 158 p.

Research output: ThesisPhD Thesis - Research UT, graduation UTAcademic

File
14 Citations (Scopus)

Electrokinetic sorting and collection of fractions for preparative capillary electrophoresis on a chip

Zalewski, D. R., Schlautmann, S., Schasfoort, R. B. M. & Gardeniers, J. G. E., 2008, In : Lab on a chip. 8, 5, p. 801-809 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

43 Downloads (Pure)

Microfluidic Free-Flow Electrophoresis for Proteomics-on-a-Chip

Kohlheyer, D., 20 Jun 2008, enschede: ippskamp. 186 p.

Research output: ThesisPhD Thesis - Research UT, graduation UTAcademic

File
Electrophoresis
Microfluidics
Electrolysis
Gases
Membranes
124 Citations (Scopus)

Miniaturizing free-flow electrophoresis - A critical review

Kohlheyer, D., Kohlheyer, D., Eijkel, J. C. T., van den Berg, A. & Schasfoort, R. B. M., Jan 2008, In : Electrophoresis. 29, 69160R/5, p. 977-993 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

13 Downloads (Pure)

On-chip electrokinetic sample focusing for microarray-based biomolecular interaction assays

Krishnamoorthy, G., Carlen, E., Kohlheyer, D., Schasfoort, R. B. M. & van den Berg, A., 12 Oct 2008, 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences. California: Chemical and Biological Micro Systems Society, p. 311-313 3 p. (microTAS; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

File
2007
94 Citations (Scopus)

Angle-scanning SPR imaging for detection of biomolecular interactions on microarrays

Beusink, J. B., Beusink, J. B., Lokate, A. M. C., Besselink, G. A. J., Pruijn, G. J. M. & Schasfoort, R. B. M., 31 Aug 2007, In : Biosensors and bioelectronics. 23, Paper P-NS/6, p. 839-844 6 p., 10.1016/j.bios.2007.08.025.

Research output: Contribution to journalArticleAcademicpeer-review

70 Citations (Scopus)

Biomolecular Interaction Monitoring of Autoantibodies by Scanning Surface Plasmon Resonance Microarray Imaging

Lokate, A. M. C., Beusink, J. B., Besselink, G. A. J., Pruijn, G. J. M. & Schasfoort, R. B. M., 17 Oct 2007, In : Journal of the American Chemical Society. 129, 7/45, p. 14013-14018 6 p., 10.1021/ja075103x.

Research output: Contribution to journalArticleAcademicpeer-review

26 Citations (Scopus)
24 Downloads (Pure)

Combined Lab-on-a-Chip and microarray approach for biomolecular interaction sensing using surface plasmon resonance imaging

Krishnamoorthy, G., Krishnamoorthy, G., Beusink, J. B., Beusink, J. B., Carlen, E., Schlautmann, S., de Boer, H. L., van den Berg, A. & Schasfoort, R. B. M., 7 Oct 2007, Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences - The proceedings of microTAS 2007 Conference. Viovy, J. L., Tabeling, P., Descroix, S. & Malaquin, L. (eds.). San Diego: Chemical and Biological Micro Systems Society, p. 676-678 3 p. (Micro Total Analysis Systems; vol. 1, no. Paper P-NS).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

File

Design and optimization of automated fraction collector

Zalewski, D. R., Schlautmann, S., Schasfoort, R. B. M. & Gardeniers, J. G. E., 7 Oct 2007, Proceedings of µTAS 2007 Conference. MicroTAS, p. 1408-1410

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

80 Citations (Scopus)

Microfluidic high-resolution free-flow isoelectric focusing

Kohlheyer, D., Eijkel, J. C. T., Schlautmann, S., van den Berg, A. & Schasfoort, R. B. M., 1 Nov 2007, In : Analytical chemistry. 79, 7/21, p. 8190-8198 9 p., 10.1021/ac071419B.

Research output: Contribution to journalArticleAcademicpeer-review

12 Downloads (Pure)

Proteomics-on-a-chip for Biomarker discovery

Schasfoort, R. B. M., Kohlheyer, D., Schlautmann, S., Eijkel, J. C. T. & van den Berg, A., 7 Oct 2007, Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences - The proceedings of microTAS 2007 Conference. Viovy, J. L., Tabeling, P., Descroix, S. & Malaquin, L. (eds.). San Diego: The Chemical and Biological Microsystems Society, p. 1243-1245 3 p. (Micro Total Analysis Systems; vol. 2, no. 7).

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

File
2006

Automated all-fractions collection for microfluidic separation

Zalewski, D. R., Schlautmann, S. & Schasfoort, R. B. M., 2006, Proceedings of alphaTas 2006 Conference. Kitamori, T., Fujita, H. & Hasebe, S. (eds.). Tokyo: Society for Chemistry and Micro-Nano Systems, p. 927-929 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Automated SPR imaging of peptide microarrays for analyte detection for multi-analyte detection of Rheumatoid Arthritis

Lokate, A. C. M., Beusink, J. B., Besselink, G. A. J., Pruijn, G. J. M. & Schasfoort, R. B. M., 8 Nov 2006, p. -.

Research output: Contribution to conferencePosterOther research output

Biochips for multi-analyte diagnostics

Tudos, A. J. & Schasfoort, R. B. M., 11 Jan 2006, p. -.

Research output: Contribution to conferencePosterOther research output

Field-Effect Flow Control for Microfabricated Fluidic Networks

Schasfoort, R. B. M., Schlautmann, S., Hendrikse, J. & van den Berg, A., 5 Nov 2006.

Research output: Contribution to conferencePosterOther research output

122 Citations (Scopus)
1 Downloads (Pure)

Free flow zone electrophoresis and isoelectric focusing using a microfabricated glass device with ion permeable membranes

Kohlheyer, D., Besselink, G. A. J., Schlautmann, S. & Schasfoort, R. B. M., 2006, In : Lab on a chip. 6, p. 374-380 7 p.

Research output: Contribution to journalArticleAcademicpeer-review