R.B.M. Schasfoort

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  • 3093 Citations
  • 24 h-Index
1989 …2018
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Research Output 1989 2018

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Article
2018
1 Citation (Scopus)
7 Downloads (Pure)

Nanoparticle Enhancement Cascade for Sensitive Multiplex Measurements of Biomarkers in Complex Fluids with Surface Plasmon Resonance Imaging

Hendriks, J., Stojanovic, I., Schasfoort, R. B. M., Saris, D. B. F. & Karperien, M., 5 Jun 2018, In : Analytical chemistry. 90, 11, p. 6563-6571 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Surface plasmon resonance
Biomarkers
Nanoparticles
Imaging techniques
Fluids
3 Citations (Scopus)

Spermine induced reversible collapse of deoxyribonucleic acid-bridged nanoparticle-based assemblies

Göeken, K. L., Schasfoort, R. B. M., Subramaniam, V. & Gill, R., 1 Jan 2018, In : Nano research. 11, 1, p. 383-396 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Spermine
DNA
Nanoparticles
Surface plasmon resonance
Geometry
2017
8 Citations (Scopus)
56 Downloads (Pure)

Isolation of single cells for protein therapeutics using microwell selection and Surface Plasmon Resonance imaging

Abali, F., Stevens, M., Tibbe, A. G. J., Terstappen, L. W. M. M., van der Velde, P. N. & Schasfoort, R. B. M., 15 Aug 2017, In : Analytical biochemistry. 531, p. 45-47 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Surface Plasmon Resonance
Surface plasmon resonance
Imaging techniques
Punching
Sorting
6 Citations (Scopus)

Surface plasmon resonance is an analytically sensitive method for antigen profiling of extracellular vesicles

Gool, E. L., Stojanovic, I., Schasfoort, R. B. M., Sturk, A., Van Leeuwen, T. G., Nieuwland, R., Terstappen, L. W. M. M. & Coumans, F. A. W., 1 Oct 2017, In : Clinical chemistry. 63, 10, p. 1633-1641 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Surface Plasmon Resonance
Surface plasmon resonance
Antigens
Imaging techniques
Flow cytometry
2016
4 Citations (Scopus)
51 Downloads (Pure)

Detection of apoptosis in cancer cell lines using Surface Plasmon Resonance imaging

Stojanović, I., van Hal, Y., van der Velden, T. J. G., Schasfoort, R. B. M. & Terstappen, L. W. M. M., 6 Jan 2016, In : Sensing and bio-sensing research. 7, p. 48-54

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
Surface Plasmon Resonance
Surface plasmon resonance
Cell death
Cytochromes
Cells
10 Citations (Scopus)

Interpolation method for accurate affinity ranking of arrayed ligand analyte interactions

Schasfoort, R. B. M., Andree, K. C., van der Velde, N., van der Kooi, A., Stojanovic, I. & Terstappen, L. W. M. M., 13 Feb 2016, In : Analytical biochemistry. 500, p. 21-23

Research output: Contribution to journalArticleAcademicpeer-review

Interpolation
Ligands
Surface Plasmon Resonance
Equilibrium constants
Surface plasmon resonance
3 Citations (Scopus)

Modeling single cell antibody excretion on a biosensor

Stojanovic, I., Baumgartner, W., van der Velden, T. J. G., Terstappen, L. W. M. M. & Schasfoort, R. B. M., 31 Mar 2016, In : Analytical biochemistry. 504, p. 1-3

Research output: Contribution to journalArticleAcademicpeer-review

Biosensing Techniques
Biosensors
Surface Plasmon Resonance
Surface plasmon resonance
Antibodies
2 Citations (Scopus)

Scaffolding of cystine-stabilized miniproteins

Sankaran, S., Stojanovic, I., Barendregt, A., Heck, A. J. R., Schasfoort, R. B. M. & Jonkheijm, P., 2016, In : ChemistrySelect. 1, 5, p. 1039-1046 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cystine
Trypsin
Trypsin Inhibitors
Vascular Endothelial Growth Factor A
Assays
2015
31 Citations (Scopus)

C-reactive protein enhances IgG-mediated phagocyte responses and thrombocytopenia

Kapur, R., Heitink-Pollé, K. M. J., Porcelijn, L., Bentlange, A. E. H., Bruin, M. C. A., Visser, R., Roos, D., Schasfoort, R. B. M., Vidarsson, G., de Haas, M. & van der Schoot, C. E., 2015, In : Blood. 125, 11, p. 1793-1802

Research output: Contribution to journalArticleAcademicpeer-review

Phagocytes
Platelets
Thrombocytopenia
C-Reactive Protein
Immunoglobulin G
10 Citations (Scopus)

Label-Free Glycoprofiling with Multiplex Surface Plasmon Resonance: A Tool To Quantify Sialylation of Erythropoietin.

Geuijen, K. P. M., Halim, L. A., Schellekens, H., Schasfoort, R. B. M., Wijffels, R. H. & Eppink, M. H. M., 2015, In : Analytical chemistry. 87, 16, p. 8115-8122

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)

Platinum(II) as bifunctional linker in antibody-drug conjugate formation: Coupling of a 4-nitrobenzo-2-oxa-1,3-diazole fluorophore to trastuzumab as a model.

Waalboer, D. C. J., Muns, J. A., Sijbrandi, N. J., Schasfoort, R. B. M., Haselberg, R., Somsen, G. W., Houthoff, H. J. & van Dongen, G. A. M. S., 2015, In : ChemMedChem. 10, 5, p. 797-803

Research output: Contribution to journalArticleAcademicpeer-review

17 Citations (Scopus)
4 Downloads (Pure)

Quantification of antibody production of individual hybridoma cells by Surface Plasmon Resonance imaging.

Stojanovic, I., van der Velden, T. J. G., Mulder, H. W., Schasfoort, R. B. M. & Terstappen, L. W. M. M., 2015, In : Analytical biochemistry. 485, p. 112-118

Research output: Contribution to journalArticleAcademicpeer-review

Surface Plasmon Resonance
Hybridomas
Surface plasmon resonance
Antibody Formation
Imaging techniques
2014
3 Citations (Scopus)

High-throughput and multiplexed regeneration buffer scouting for affinity-based interactions

Geuijen, K. P. M., Schasfoort, R. B. M., Wijffels, R. H. & Eppink, M. H. M., 2014, In : Analytical biochemistry. 454, p. 38-40

Research output: Contribution to journalArticleAcademicpeer-review

Regeneration
Buffers
Throughput
Ligands
Biosensors
2013
44 Citations (Scopus)

Analysis of cell surface antigens by Surface Plasmon Resonance imaging

Stojanovic, I., Schasfoort, R. B. M. & Terstappen, L. W. M. M., 11 Apr 2013, In : Biosensors and bioelectronics. 52, p. 36-43

Research output: Contribution to journalArticleAcademicpeer-review

Surface Plasmon Resonance
Surface plasmon resonance
Surface Antigens
Antigens
Image sensors

Label-free cell profiling

Schasfoort, R. B. M., Bentlage, A. E. H., Stojanovic, I., van der Kooi, A., van der Schoot, E., Terstappen, L. W. M. M. & Vidarsson, G., 2013, In : Analytical biochemistry. 439, 1, p. 4-6

Research output: Contribution to journalArticleAcademicpeer-review

Labels
Blood
Erythrocytes
Surface Plasmon Resonance
Sensors
2012
9 Citations (Scopus)

Method for estimating the single molecular affinity

Schasfoort, R. B. M., de Lau, W., van der Kooi, A., Clevers, H. & Engbers, G. H. M., 2012, In : Analytical biochemistry. 421, 2, p. 794-796

Research output: Contribution to journalArticleAcademicpeer-review

Ligands
Equilibrium constants
Surface plasmon resonance
Biosensors
Labels
2011
690 Citations (Scopus)

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

de Lau, W., Barker, N., Low, T. Y., Koo, B-K., Li, V. S. W., Teunissen, H., Kujala, P., Haegebarth, A., Peters, P. J. M., van de Wetering, M., Stange, D. E., Es, J. E., Guardavaccaro, D., Schasfoort, R. B. M., Mohri, Y., Nishimori, K., Mohammed, S., Heck, A. J. R. & Clevers, H., 2011, In : Nature. 476, 7360, p. 293-297

Research output: Contribution to journalArticleAcademicpeer-review

Wnt Receptors
Wnt Signaling Pathway
Adult Stem Cells
HEK293 Cells
Gene Deletion
2010
34 Citations (Scopus)

Electrokinetic label-free screening chip: a marriage of multiplexing and high throughput analysis using surface plasmon resonance imaging

Krishnamoorthy, G., Carlen, E., Bomer, J. G., Wijnperle, D., de Boer, H. L., van den Berg, A. & Schasfoort, R. B. M., 2010, In : Lab on a chip. 10, 8, p. 986-990 5 p., 10.1039/c000705f.

Research output: Contribution to journalArticleAcademicpeer-review

23 Citations (Scopus)

Electrokinetic Lab-on-a-BioChip for Multi-ligand/Multi-analyte Biosensing

Krishnamoorthy, G., Carlen, E., de Boer, H. L., van den Berg, A. & Schasfoort, R. B. M., 15 May 2010, In : Analytical chemistry. 82, 10, p. 4145-4150 6 p., 10.1021/ac1003163.

Research output: Contribution to journalArticleAcademicpeer-review

33 Citations (Scopus)
29 Downloads (Pure)

Mapping of citrullinated fibrinogen B-cell epitopes in rheumatoid arthritis by imaging surface plasmon resonance

van Beers, J. J. B. C., Raijmakers, R., Alexander, L-E., Stammen-Vogelzangs, J., Lokate, A. M. C., Heck, A. J. R., Schasfoort, R. B. M. & Pruijn, G. J. M., 2010, In : Arthritis research & therapy. 12, 6, p. - 10 p., R219.

Research output: Contribution to journalArticleAcademicpeer-review

File
B-Lymphocyte Epitopes
Surface Plasmon Resonance
Fibrinogen
Rheumatoid Arthritis
Peptides
15 Citations (Scopus)

Surface plasmon resonance imaging based multiplex biosensor: Integration of biomolecular screening, detection and kinetics estimation.

Krishnamoorthy, G., Carlen, E., van den Berg, A. & Schasfoort, R. B. M., 15 Jul 2010, In : Sensors and actuators. B: Chemical. 148, 2, p. 511-521 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

2009

Integrated electrokinetic sample focusing and surface plasmon resonance imaging system for measuring biomolecular interactions

Krishnamoorthy, G., Carlen, E., Kohlheyer, D., Schasfoort, R. B. M. & van den Berg, A., 2009, In : Analytical chemistry. 81, 5, p. 1957-1963

Research output: Contribution to journalArticleAcademicpeer-review

22 Citations (Scopus)

Integrated Electrokinetic Sample Focusing and Surface Plasmon Resonance Imaging System for Measuring Biomolecular Interactions

Krishnamoorthy, G., Carlen, E., Kohlheyer, D., Schasfoort, R. B. M. & van den Berg, A., 1 Mar 2009, In : Analytical chemistry. 81, 5, p. 1957-1963 7 p., 10.1021/ac802668z.

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)

Single injection microarray-based biosensor kinetics

Krishnamoorthy, G., Carlen, E., Beusink, J. B., Schasfoort, R. B. M. & van den Berg, A., 2009, In : Analytical methods. 1, 3, p. 162-169

Research output: Contribution to journalArticleAcademicpeer-review

Microarrays
Biosensors
Immunoglobulin G
Ligands
Kinetics
2008
13 Citations (Scopus)
26 Downloads (Pure)

A microfluidic device for array patterning by perpendicular electrokinetic focusing

Kohlheyer, D., Unnikrishnan, S., Besselink, G. A. J., Schlautmann, S. & Schasfoort, R. B. M., Jun 2008, In : Microfluidics and nanofluidics. 4, Paper P-NS/6, p. 557-564 8 p., 10.1007/s10404-007-0217-9.

Research output: Contribution to journalArticleAcademicpeer-review

File
55 Citations (Scopus)

Bubble-Free Operation of a Microfluidic Free-Flow Electrophoresis Chip with Integrated Pt Electrodes

Kohlheyer, D., Eijkel, J. C. T., Schlautmann, S., van den Berg, A. & Schasfoort, R. B. M., 1 Jun 2008, In : Analytical chemistry. 80, 11, p. 4111-4118 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)

Electrokinetic sorting and collection of fractions for preparative capillary electrophoresis on a chip

Zalewski, D. R., Schlautmann, S., Schasfoort, R. B. M. & Gardeniers, J. G. E., 2008, In : Lab on a chip. 8, 5, p. 801-809 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

124 Citations (Scopus)

Miniaturizing free-flow electrophoresis - A critical review

Kohlheyer, D., Kohlheyer, D., Eijkel, J. C. T., van den Berg, A. & Schasfoort, R. B. M., Jan 2008, In : Electrophoresis. 29, 69160R/5, p. 977-993 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

2007
95 Citations (Scopus)

Angle-scanning SPR imaging for detection of biomolecular interactions on microarrays

Beusink, J. B., Beusink, J. B., Lokate, A. M. C., Besselink, G. A. J., Pruijn, G. J. M. & Schasfoort, R. B. M., 31 Aug 2007, In : Biosensors and bioelectronics. 23, Paper P-NS/6, p. 839-844 6 p., 10.1016/j.bios.2007.08.025.

Research output: Contribution to journalArticleAcademicpeer-review

70 Citations (Scopus)

Biomolecular Interaction Monitoring of Autoantibodies by Scanning Surface Plasmon Resonance Microarray Imaging

Lokate, A. M. C., Beusink, J. B., Besselink, G. A. J., Pruijn, G. J. M. & Schasfoort, R. B. M., 17 Oct 2007, In : Journal of the American Chemical Society. 129, 7/45, p. 14013-14018 6 p., 10.1021/ja075103x.

Research output: Contribution to journalArticleAcademicpeer-review

80 Citations (Scopus)

Microfluidic high-resolution free-flow isoelectric focusing

Kohlheyer, D., Eijkel, J. C. T., Schlautmann, S., van den Berg, A. & Schasfoort, R. B. M., 1 Nov 2007, In : Analytical chemistry. 79, 7/21, p. 8190-8198 9 p., 10.1021/ac071419B.

Research output: Contribution to journalArticleAcademicpeer-review

2006
122 Citations (Scopus)
1 Downloads (Pure)

Free flow zone electrophoresis and isoelectric focusing using a microfabricated glass device with ion permeable membranes

Kohlheyer, D., Besselink, G. A. J., Schlautmann, S. & Schasfoort, R. B. M., 2006, In : Lab on a chip. 6, p. 374-380 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

High Density Protein Micro Arrays

Schasfoort, R. B. M., Verdoold, R. & Beusink, J. B., 2006, In : Bioforum Europe. 10, p. 60-62 3 p.

Research output: Contribution to journalArticleAcademic

2005

BioArrays Europe 2005

Tudos, A. J. & Schasfoort, R. B. M., 2005, In : Expert review of molecular diagnostics. 5, 6, p. 851-856 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

23 Citations (Scopus)

Electroosmotically controllable multi-flow microreactor

Kohlheyer, D., Besselink, G. A. J., Lammertink, R. G. H., Schlautmann, S., Unnikrishnan, S. & Schasfoort, R. B. M., 2005, In : Microfluidics and nanofluidics. 1, 3, p. 242-248 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

2004
22 Citations (Scopus)

Electroosmotic guiding of sample flows in a laminar flow chamber

Besselink, G. A. J., Vulto, P., Lammertink, R. G. H., Schlautmann, S., van den Berg, A., Olthuis, W., Engbers, G. H. M. & Schasfoort, R. B. M., 2004, In : Electrophoresis. 25, 21-22, p. 3705-3711 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

28 Citations (Scopus)

Proteomics-on-a-chip: the challenge to couple lab-on-a-chip unit open

Schasfoort, R. B. M., 2004, In : Expert review of proteomics. 1, 1, p. 123-132 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)

Recirculation of Nanoliter Volumes within Microfluidic Channels

Lammertink, R. G. H., Schlautmann, S., Besselink, G. A. J. & Schasfoort, R. B. M., 2004, In : Analytical chemistry. 76, 11, p. 3018-3022 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

83 Citations (Scopus)

Signal amplification on planar and gel-type sensor surfaces in surface plasmon resonance-based detection of prostate-specific antigen

Besselink, G. A. J., Kooyman, R. P. H., van Os, P. J. H. J., Engbers, G. H. M. & Schasfoort, R. B. M., 2004, In : Analytical biochemistry. 333, 1, p. 165-173 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

2003
43 Citations (Scopus)

Fabrication of a microfluidic chip by UV bonding at room temperature for integration of temperature-sensitive layers

Schlautmann, S., Besselink, G. A. J., Prabhu, R. & Schasfoort, R. B. M., 2003, In : Journal of micromechanics and microengineering. 13, p. S81-S84 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

32 Citations (Scopus)

Modification of ISFETs with a monolayer of latex beads for specific detection of proteins

Besselink, G. A. J., Schasfoort, R. B. M. & Bergveld, P., 2003, In : Biosensors and bioelectronics. 18, 9, p. 1109-1114 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

2001
110 Citations (Scopus)

New approaches for fabrication of microfluidic capillary electrophoresis devices with on-chip conductivity detection

Guijt, R. M., Baltussen, E., van der Steen, G., Schasfoort, R. B. M., Schlautmann, S., Billiet, H. A. H., Frank, J., van Dedem, G. W. K. & van den Berg, A., 2001, In : Electrophoresis. 22, 2, p. 235-241

Research output: Contribution to journalArticleAcademic

90 Citations (Scopus)
Capillary electrophoresis
Microfabrication
Blasting
Powders
Microfluidics
351 Citations (Scopus)

Trends in miniaturized total analysis systems for point-of-care testing in clinical chemistry

Tudos, A. J., Besselink, G. A. J. & Schasfoort, R. B. M., 2001, In : Lab on a chip. 1, 1, p. 83-95 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

2000
13 Citations (Scopus)
49 Downloads (Pure)

An ISFET-based anion sensor for the potentiometric detection of organic acids in liquid chromatography

Poels, I., Schasfoort, R. B. M., Picioreanu, S., Frank, J., van Dedem, G. W. K., van den Berg, A. & Nagels, L. J., 2000, In : Sensors and actuators. B: Chemical. 67, 67 is3, p. 194-299 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

File

Technologies and devices for micro chemical systems

Gardeniers, H., Schasfoort, R. & van den Berg, A., 2000, In : MST news. 2000, 4, p. 10-13

Research output: Contribution to journalArticleAcademic

Open Access
File
Lab-on-a-chip
Chemical compounds
Cations
Chemical reactions
Blood
1999
391 Citations (Scopus)

Field-effect flow control for microfabricated fluidic networks

Schasfoort, R. B. M., Schlautmann, S., Hendrikse, J. & van den Berg, A., 1999, In : Science. 286, 5441, p. 942-945

Research output: Contribution to journalArticleAcademicpeer-review

Fluidics
Field effect transistors
Flow control
Microfluidics
Microelectronics
1995
36 Citations (Scopus)
37 Downloads (Pure)

The ISFET based heparin sensor with a monolayer of protamine as affinity ligand

van Kerkhof, J. C., van Kerkhof, J. C., Bergveld, P. & Schasfoort, R. B. M., 1995, In : Biosensors and bioelectronics. 10, 3-4, p. 269-282

Research output: Contribution to journalArticleAcademicpeer-review

File
1994
27 Citations (Scopus)
73 Downloads (Pure)

Nucleic acid detection with surface plasmon resonance using cationic latex

de Vries, E. F. A., Schasfoort, R. B. M., van der Plas, J. & Greve, J., 1994, In : Biosensors and bioelectronics. 9, 7, p. 509-514

Research output: Contribution to journalArticleAcademic

File
1993
20 Citations (Scopus)
40 Downloads (Pure)

Development of an ISFET based heparin sensor using the ion-step measuring method

van Kerkhof, J. C., van Kerkhof, J. C., Bergveld, P. & Schasfoort, R. B. M., 1993, In : Biosensors and bioelectronics. 8, 9/10, p. 463-472

Research output: Contribution to journalArticleAcademicpeer-review

File