Separation in organic mixtures is challenging but inevitable in many chemical and pharmaceutical processes. A membrane-based technique known as organic solvent nanofiltration (OSN) offers a sustainable and reliable solution due to its characteristics of low energy consumption and high efficiency. However, fabrication of a robust membrane that can maintain its separation performance in direct contact with organic solvents for a long period of time is challenging. The most common way to make a polymeric membrane resistant to organic solvents is to cross-link it with a three-dimensional network of polymer chains. However, selection of the right cross-linker for a particular polymer may not be very straightforward. Therefore, in this review, we aim to briefly introduce the common materials used for the fabrication of OSN membranes and demonstrate the state-of-art cross-linking procedures to improve the chemical stability of the membranes. This review may be helpful to researchers when selecting and modifying materials for the development of OSN membranes.
Tashvigh, A. A., Feng, Y., Weber, M., Maletzko, C., & Chung, T-S. (2019). 110th Anniversary: Selection of Cross-Linkers and Cross-Linking Procedures for the Fabrication of Solvent-Resistant Nanofiltration Membranes: A Review. Industrial and engineering chemistry research, 58(25), 10678-10691. https://doi.org/10.1021/acs.iecr.9b02408