18F-FDG PET/CT in Detecting Metastatic Infection in Children

Ilse J.E. Kouijzer; Gijsbert J. Blokhuis; Jos M. Th. Draaisma; Wim J.G. Oyen; Lioe-Fee de Geus-Oei; Chantal P. Bleeker-Rovers

doi:10.1097/RLU.0000000000001119

18F-FDG PET/CT in Detecting Metastatic Infection in Children

Ilse J.E. Kouijzer, Gijsbert J. Blokhuis, Jos M. Th. Draaisma, Wim J.G. Oyen, Lioe-Fee de Geus-Oei, Chantal P. Bleeker-Rovers

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Abstract

Purpose of the Report: Metastatic infection is a severe complication of bacteremia with high morbidity and mortality. The aim of this study was to investigate the diagnostic value of 18F-FDG PET combined with CT (FDG PET/CT) in children suspected of having metastatic infection. Methods: The results of FDG PET/CT scans performed in children because of suspected metastatic infection from September 2003 to June 2013 were analyzed retrospectively. The results were compared with the final clinical diagnosis. Results: FDG PET/CT was performed in 13 children with suspected metastatic infection. Of the total number of FDG PET/CT scans, 38% were clinically helpful. Positive predictive value of FDG PET/CT was 71%, and negative predictive value was 100%. Conclusions: FDG PET/CT appears to be a valuable diagnostic technique in children with suspected metastatic infection. Prospective studies of FDG PET/CT as part of a structured diagnostic protocol are needed to assess the exact additional diagnostic value

Original language	English
Pages (from-to)	278-281
Journal	Clinical nuclear medicine
Volume	41
Issue number	4
DOIs	https://doi.org/10.1097/RLU.0000000000001119
Publication status	Published - 2016

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n/a OA procedure

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10.1097/RLU.0000000000001119

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title = "18F-FDG PET/CT in Detecting Metastatic Infection in Children",

abstract = "Purpose of the Report: Metastatic infection is a severe complication of bacteremia with high morbidity and mortality. The aim of this study was to investigate the diagnostic value of 18F-FDG PET combined with CT (FDG PET/CT) in children suspected of having metastatic infection. Methods: The results of FDG PET/CT scans performed in children because of suspected metastatic infection from September 2003 to June 2013 were analyzed retrospectively. The results were compared with the final clinical diagnosis. Results: FDG PET/CT was performed in 13 children with suspected metastatic infection. Of the total number of FDG PET/CT scans, 38% were clinically helpful. Positive predictive value of FDG PET/CT was 71%, and negative predictive value was 100%. Conclusions: FDG PET/CT appears to be a valuable diagnostic technique in children with suspected metastatic infection. Prospective studies of FDG PET/CT as part of a structured diagnostic protocol are needed to assess the exact additional diagnostic value",

keywords = "n/a OA procedure",

author = "Kouijzer, {Ilse J.E.} and Blokhuis, {Gijsbert J.} and Draaisma, {Jos M. Th.} and Oyen, {Wim J.G.} and {de Geus-Oei}, Lioe-Fee and Bleeker-Rovers, {Chantal P.}",

year = "2016",

doi = "10.1097/RLU.0000000000001119",

language = "English",

volume = "41",

pages = "278--281",

journal = "Clinical nuclear medicine",

issn = "0363-9762",

publisher = "Lippincott Williams & Wilkins",

number = "4",

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TY - JOUR

T1 - 18F-FDG PET/CT in Detecting Metastatic Infection in Children

AU - Kouijzer, Ilse J.E.

AU - Blokhuis, Gijsbert J.

AU - Draaisma, Jos M. Th.

AU - Oyen, Wim J.G.

AU - de Geus-Oei, Lioe-Fee

AU - Bleeker-Rovers, Chantal P.

PY - 2016

Y1 - 2016

N2 - Purpose of the Report: Metastatic infection is a severe complication of bacteremia with high morbidity and mortality. The aim of this study was to investigate the diagnostic value of 18F-FDG PET combined with CT (FDG PET/CT) in children suspected of having metastatic infection. Methods: The results of FDG PET/CT scans performed in children because of suspected metastatic infection from September 2003 to June 2013 were analyzed retrospectively. The results were compared with the final clinical diagnosis. Results: FDG PET/CT was performed in 13 children with suspected metastatic infection. Of the total number of FDG PET/CT scans, 38% were clinically helpful. Positive predictive value of FDG PET/CT was 71%, and negative predictive value was 100%. Conclusions: FDG PET/CT appears to be a valuable diagnostic technique in children with suspected metastatic infection. Prospective studies of FDG PET/CT as part of a structured diagnostic protocol are needed to assess the exact additional diagnostic value

AB - Purpose of the Report: Metastatic infection is a severe complication of bacteremia with high morbidity and mortality. The aim of this study was to investigate the diagnostic value of 18F-FDG PET combined with CT (FDG PET/CT) in children suspected of having metastatic infection. Methods: The results of FDG PET/CT scans performed in children because of suspected metastatic infection from September 2003 to June 2013 were analyzed retrospectively. The results were compared with the final clinical diagnosis. Results: FDG PET/CT was performed in 13 children with suspected metastatic infection. Of the total number of FDG PET/CT scans, 38% were clinically helpful. Positive predictive value of FDG PET/CT was 71%, and negative predictive value was 100%. Conclusions: FDG PET/CT appears to be a valuable diagnostic technique in children with suspected metastatic infection. Prospective studies of FDG PET/CT as part of a structured diagnostic protocol are needed to assess the exact additional diagnostic value

KW - n/a OA procedure

U2 - 10.1097/RLU.0000000000001119

DO - 10.1097/RLU.0000000000001119

M3 - Article

SN - 0363-9762

VL - 41

SP - 278

EP - 281

JO - Clinical nuclear medicine

JF - Clinical nuclear medicine

IS - 4

ER -

18F-FDG PET/CT in Detecting Metastatic Infection in Children

Abstract

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