18F-FDG PET/CT in Detecting Metastatic Infection in Children

Ilse Johanna Elsa Kouijzer, Gijsbert J. Blokhuis, Jos M. Th. Draaisma, Wim J.G. Oyen, Lioe-Fee de Geus-Oei, Chantal P. Bleeker-Rovers

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Abstract

Purpose of the Report: Metastatic infection is a severe complication of bacteremia with high morbidity and mortality. The aim of this study was to investigate the diagnostic value of 18F-FDG PET combined with CT (FDG PET/CT) in children suspected of having metastatic infection. Methods: The results of FDG PET/CT scans performed in children because of suspected metastatic infection from September 2003 to June 2013 were analyzed retrospectively. The results were compared with the final clinical diagnosis. Results: FDG PET/CT was performed in 13 children with suspected metastatic infection. Of the total number of FDG PET/CT scans, 38% were clinically helpful. Positive predictive value of FDG PET/CT was 71%, and negative predictive value was 100%. Conclusions: FDG PET/CT appears to be a valuable diagnostic technique in children with suspected metastatic infection. Prospective studies of FDG PET/CT as part of a structured diagnostic protocol are needed to assess the exact additional diagnostic value
Original languageEnglish
Pages (from-to)278-281
JournalClinical nuclear medicine
Volume41
Issue number4
DOIs
Publication statusPublished - 2016

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Fluorodeoxyglucose F18
Infection
Bacteremia
Prospective Studies
Morbidity
Mortality

Keywords

  • METIS-316343
  • IR-100173

Cite this

Kouijzer, I. J. E., Blokhuis, G. J., Draaisma, J. M. T., Oyen, W. J. G., de Geus-Oei, L-F., & Bleeker-Rovers, C. P. (2016). 18F-FDG PET/CT in Detecting Metastatic Infection in Children. Clinical nuclear medicine, 41(4), 278-281. https://doi.org/10.1097/RLU.0000000000001119
Kouijzer, Ilse Johanna Elsa ; Blokhuis, Gijsbert J. ; Draaisma, Jos M. Th. ; Oyen, Wim J.G. ; de Geus-Oei, Lioe-Fee ; Bleeker-Rovers, Chantal P. / 18F-FDG PET/CT in Detecting Metastatic Infection in Children. In: Clinical nuclear medicine. 2016 ; Vol. 41, No. 4. pp. 278-281.
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title = "18F-FDG PET/CT in Detecting Metastatic Infection in Children",
abstract = "Purpose of the Report: Metastatic infection is a severe complication of bacteremia with high morbidity and mortality. The aim of this study was to investigate the diagnostic value of 18F-FDG PET combined with CT (FDG PET/CT) in children suspected of having metastatic infection. Methods: The results of FDG PET/CT scans performed in children because of suspected metastatic infection from September 2003 to June 2013 were analyzed retrospectively. The results were compared with the final clinical diagnosis. Results: FDG PET/CT was performed in 13 children with suspected metastatic infection. Of the total number of FDG PET/CT scans, 38{\%} were clinically helpful. Positive predictive value of FDG PET/CT was 71{\%}, and negative predictive value was 100{\%}. Conclusions: FDG PET/CT appears to be a valuable diagnostic technique in children with suspected metastatic infection. Prospective studies of FDG PET/CT as part of a structured diagnostic protocol are needed to assess the exact additional diagnostic value",
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author = "Kouijzer, {Ilse Johanna Elsa} and Blokhuis, {Gijsbert J.} and Draaisma, {Jos M. Th.} and Oyen, {Wim J.G.} and {de Geus-Oei}, Lioe-Fee and Bleeker-Rovers, {Chantal P.}",
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Kouijzer, IJE, Blokhuis, GJ, Draaisma, JMT, Oyen, WJG, de Geus-Oei, L-F & Bleeker-Rovers, CP 2016, '18F-FDG PET/CT in Detecting Metastatic Infection in Children' Clinical nuclear medicine, vol. 41, no. 4, pp. 278-281. https://doi.org/10.1097/RLU.0000000000001119

18F-FDG PET/CT in Detecting Metastatic Infection in Children. / Kouijzer, Ilse Johanna Elsa; Blokhuis, Gijsbert J.; Draaisma, Jos M. Th.; Oyen, Wim J.G.; de Geus-Oei, Lioe-Fee; Bleeker-Rovers, Chantal P.

In: Clinical nuclear medicine, Vol. 41, No. 4, 2016, p. 278-281.

Research output: Contribution to journalArticleAcademicpeer-review

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T1 - 18F-FDG PET/CT in Detecting Metastatic Infection in Children

AU - Kouijzer, Ilse Johanna Elsa

AU - Blokhuis, Gijsbert J.

AU - Draaisma, Jos M. Th.

AU - Oyen, Wim J.G.

AU - de Geus-Oei, Lioe-Fee

AU - Bleeker-Rovers, Chantal P.

PY - 2016

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N2 - Purpose of the Report: Metastatic infection is a severe complication of bacteremia with high morbidity and mortality. The aim of this study was to investigate the diagnostic value of 18F-FDG PET combined with CT (FDG PET/CT) in children suspected of having metastatic infection. Methods: The results of FDG PET/CT scans performed in children because of suspected metastatic infection from September 2003 to June 2013 were analyzed retrospectively. The results were compared with the final clinical diagnosis. Results: FDG PET/CT was performed in 13 children with suspected metastatic infection. Of the total number of FDG PET/CT scans, 38% were clinically helpful. Positive predictive value of FDG PET/CT was 71%, and negative predictive value was 100%. Conclusions: FDG PET/CT appears to be a valuable diagnostic technique in children with suspected metastatic infection. Prospective studies of FDG PET/CT as part of a structured diagnostic protocol are needed to assess the exact additional diagnostic value

AB - Purpose of the Report: Metastatic infection is a severe complication of bacteremia with high morbidity and mortality. The aim of this study was to investigate the diagnostic value of 18F-FDG PET combined with CT (FDG PET/CT) in children suspected of having metastatic infection. Methods: The results of FDG PET/CT scans performed in children because of suspected metastatic infection from September 2003 to June 2013 were analyzed retrospectively. The results were compared with the final clinical diagnosis. Results: FDG PET/CT was performed in 13 children with suspected metastatic infection. Of the total number of FDG PET/CT scans, 38% were clinically helpful. Positive predictive value of FDG PET/CT was 71%, and negative predictive value was 100%. Conclusions: FDG PET/CT appears to be a valuable diagnostic technique in children with suspected metastatic infection. Prospective studies of FDG PET/CT as part of a structured diagnostic protocol are needed to assess the exact additional diagnostic value

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JO - Clinical nuclear medicine

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