2D-5 Ultrasonic Characterization of Novel Monodispersed Contrast Agents

William Shi; Marcel Böhmer; Suzanne de Winter; Jan Steenbakkers; Marcia Emmer; Annemieke van Wamel; Nico de Jong; Christopher S. Hall

doi:10.1109/ULTSYM.2006.88

2D-5 Ultrasonic Characterization of Novel Monodispersed Contrast Agents

William Shi, Marcel Böhmer, Suzanne de Winter, Jan Steenbakkers, Marcia Emmer, Annemieke van Wamel, Nico de Jong, Christopher S. Hall

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

7 Citations (Scopus)

Abstract

Localized drug delivery should significantly improve the therapeutic efficacy for treatment of pathological lesions and concurrently reduce toxic exposure to the surrounding healthy tissue. A novel contrast agent, consisting of mono-dispersed gas-filled microcapsules, offers great potential for localized drug release. The destruction threshold and rate of various microcapsules and their dependence on the microcapsule size and shell thickness have been investigated via optical and acoustical measurements. The results presented in this paper will increase understanding of specific physical attributes needed to improve ultrasonically-activated drug delivery particles.

Original language	English
Title of host publication	Proceedings 2006 IEEE Ultrasonics Symposium
Place of Publication	Piscataway, NJ
Publisher	IEEE
Number of pages	4
ISBN (Print)	1-4244-0201-8, 1-4244-0202-6 (CD)
DOIs	https://doi.org/10.1109/ULTSYM.2006.88
Publication status	Published - 3 Oct 2006
Externally published	Yes
Event	IEEE Ultrasonics Symposium 2006 - Vancouver, Canada Duration: 3 Oct 2006 → 6 Oct 2006

Publication series

Name	IEEE Ultrasonics Symposium (IUS)
Publisher	IEEE
Volume	2006
ISSN (Print)	1051-0117

Conference

Conference	IEEE Ultrasonics Symposium 2006
Country/Territory	Canada
City	Vancouver
Period	3/10/06 → 6/10/06

Keywords

n/a OA procedure

Access to Document

10.1109/ULTSYM.2006.88

Cite this

@inproceedings{17b25fa445c34a55852b99e260284c31,

title = "2D-5 Ultrasonic Characterization of Novel Monodispersed Contrast Agents",

abstract = "Localized drug delivery should significantly improve the therapeutic efficacy for treatment of pathological lesions and concurrently reduce toxic exposure to the surrounding healthy tissue. A novel contrast agent, consisting of mono-dispersed gas-filled microcapsules, offers great potential for localized drug release. The destruction threshold and rate of various microcapsules and their dependence on the microcapsule size and shell thickness have been investigated via optical and acoustical measurements. The results presented in this paper will increase understanding of specific physical attributes needed to improve ultrasonically-activated drug delivery particles.",

keywords = "n/a OA procedure",

author = "William Shi and Marcel B{\"o}hmer and {de Winter}, Suzanne and Jan Steenbakkers and Marcia Emmer and {van Wamel}, Annemieke and {de Jong}, Nico and Hall, {Christopher S.}",

year = "2006",

month = oct,

day = "3",

doi = "10.1109/ULTSYM.2006.88",

language = "English",

isbn = "1-4244-0201-8",

series = "IEEE Ultrasonics Symposium (IUS)",

publisher = "IEEE",

booktitle = "Proceedings 2006 IEEE Ultrasonics Symposium",

address = "United States",

note = "IEEE Ultrasonics Symposium 2006 ; Conference date: 03-10-2006 Through 06-10-2006",

}

Shi, W, Böhmer, M, de Winter, S, Steenbakkers, J, Emmer, M, van Wamel, A, de Jong, N & Hall, CS 2006, 2D-5 Ultrasonic Characterization of Novel Monodispersed Contrast Agents. in Proceedings 2006 IEEE Ultrasonics Symposium. IEEE Ultrasonics Symposium (IUS), vol. 2006, IEEE, Piscataway, NJ, IEEE Ultrasonics Symposium 2006, Vancouver, Canada, 3/10/06. https://doi.org/10.1109/ULTSYM.2006.88

TY - GEN

T1 - 2D-5 Ultrasonic Characterization of Novel Monodispersed Contrast Agents

AU - Shi, William

AU - Böhmer, Marcel

AU - de Winter, Suzanne

AU - Steenbakkers, Jan

AU - Emmer, Marcia

AU - van Wamel, Annemieke

AU - de Jong, Nico

AU - Hall, Christopher S.

PY - 2006/10/3

Y1 - 2006/10/3

N2 - Localized drug delivery should significantly improve the therapeutic efficacy for treatment of pathological lesions and concurrently reduce toxic exposure to the surrounding healthy tissue. A novel contrast agent, consisting of mono-dispersed gas-filled microcapsules, offers great potential for localized drug release. The destruction threshold and rate of various microcapsules and their dependence on the microcapsule size and shell thickness have been investigated via optical and acoustical measurements. The results presented in this paper will increase understanding of specific physical attributes needed to improve ultrasonically-activated drug delivery particles.

AB - Localized drug delivery should significantly improve the therapeutic efficacy for treatment of pathological lesions and concurrently reduce toxic exposure to the surrounding healthy tissue. A novel contrast agent, consisting of mono-dispersed gas-filled microcapsules, offers great potential for localized drug release. The destruction threshold and rate of various microcapsules and their dependence on the microcapsule size and shell thickness have been investigated via optical and acoustical measurements. The results presented in this paper will increase understanding of specific physical attributes needed to improve ultrasonically-activated drug delivery particles.

KW - n/a OA procedure

U2 - 10.1109/ULTSYM.2006.88

DO - 10.1109/ULTSYM.2006.88

M3 - Conference contribution

SN - 1-4244-0201-8

SN - 1-4244-0202-6 (CD)

T3 - IEEE Ultrasonics Symposium (IUS)

BT - Proceedings 2006 IEEE Ultrasonics Symposium

PB - IEEE

CY - Piscataway, NJ

T2 - IEEE Ultrasonics Symposium 2006

Y2 - 3 October 2006 through 6 October 2006

ER -

2D-5 Ultrasonic Characterization of Novel Monodispersed Contrast Agents

Abstract

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Conference

Keywords

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