A bubble-driven microfluidic transport element for bioengineering

Philippe Marmottant, Sascha Hilgenfeldt

Research output: Contribution to journalArticleAcademicpeer-review

155 Citations (Scopus)
90 Downloads (Pure)


Microfluidics typically uses channels to transport small objects by actuation forces such as an applied pressure difference or thermocapillarity. We propose that acoustic streaming is an alternative means of directional transport at small scales. Microbubbles on a substrate establish well controlled fluid motion on very small scales; combinations ("doublets") of bubbles and microparticles break the symmetry of the motion and constitute flow transport elements. We demonstrate the principle of doublet streaming and describe the ensuing transport. Devices based on doublet flow elements work without microchannels and are thus potentially cheap and highly parallelizable.
Original languageEnglish
Pages (from-to)9523-9527
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Issue number26
Publication statusPublished - 2004


  • METIS-218709
  • IR-47816


Dive into the research topics of 'A bubble-driven microfluidic transport element for bioengineering'. Together they form a unique fingerprint.

Cite this