TY - JOUR
T1 - A capillary micro-reactor as a tool to study pressurized reactions; The influence of pressure on the stereoselectivity of the diels-alder reaction of 2- and 3-furylmethanol with maleimides
AU - Benito-Lopez, Fernando
AU - Kettelarij, Albert J.
AU - Egberink, Richard J.M.
AU - Velders, Aldrik H.
AU - Tiggelaar, Roald M.
AU - Gardeniers, Han J.G.E.
AU - Reinhoudt, David N.
AU - Verboom, Willem
PY - 2010
Y1 - 2010
N2 - The influence of a pressure of 60 MPa on theconversion and the stereoselectivity of the Diels-Alderreaction of 2- and 3-furylmethanol with methyl-, benzyl-, andphenylmaleimide was studied in a capillary micro-reactor. Inthe case of 2-furylmethanol, a 1.7-fold higher conversion wasobtained at 60 MPa with respect to 0.1 MPa experiments.Pressure positively affects the formation of the exo isomer,whereas in the case of 3-furylmethanol pressure does notaffect the reaction.
AB - The influence of a pressure of 60 MPa on theconversion and the stereoselectivity of the Diels-Alderreaction of 2- and 3-furylmethanol with methyl-, benzyl-, andphenylmaleimide was studied in a capillary micro-reactor. Inthe case of 2-furylmethanol, a 1.7-fold higher conversion wasobtained at 60 MPa with respect to 0.1 MPa experiments.Pressure positively affects the formation of the exo isomer,whereas in the case of 3-furylmethanol pressure does notaffect the reaction.
M3 - Article
SN - 0392-839X
VL - 28
SP - 56
EP - 59
JO - Chimica oggi = Chemistry today
JF - Chimica oggi = Chemistry today
IS - 2
ER -