A cheap 2D fluorescence detection system for µM-sized beads on-Chip

Loes Irene Segerink, Maarten J. Koster, A.J. Sprenkels, I. Vermes, Albert van den Berg

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

    Abstract

    In this paper a compact fluorescence detection system for on-chip analysis of μm-sized beads is presented. The system comprises a cheap optical pickup with integrated functionalities that are used for the detection. Furthermore some other optical components are added for the fluorescence detection. Another part of the system is the microfluidic chip which contains liquid channels and optical markers used for the autofocus and channel find algorithms. Within one minute the channel of interest is found and fluorescent beads are detected in the microchannel without the need for dynamic focusing, since a twodimensional scan across the channel width is performed.
    Original languageEnglish
    Title of host publication15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, μTAS 2011
    Place of PublicationWashington
    PublisherChemical and Biological Micro Systems Society
    Pages556-558
    Number of pages3
    ISBN (Print)978-0-979-8064-4-5
    Publication statusPublished - 2 Oct 2011
    Event15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, µTAS 2011 - Seattle, United States
    Duration: 2 Oct 20116 Oct 2011
    Conference number: 15
    https://microtasconferences.org/microtas2011/

    Publication series

    Name
    PublisherChemical and Biological Microsystems Society
    ISSN (Print)1556-5904

    Conference

    Conference15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, µTAS 2011
    Abbreviated titleMicroTAS
    CountryUnited States
    CitySeattle
    Period2/10/116/10/11
    Internet address

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  • Cite this

    Segerink, L. I., Koster, M. J., Sprenkels, A. J., Vermes, I., & van den Berg, A. (2011). A cheap 2D fluorescence detection system for µM-sized beads on-Chip. In 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, μTAS 2011 (pp. 556-558). Washington: Chemical and Biological Micro Systems Society.