A fast method for in vivo lactate imaging

T. Reese, D. G. Norris, D. Leibfritz*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)


A robust method for fast lactate imaging is presented using a combination of a lactate editing sequence and a one‐shot imaging experiment. The lactate editing method is based on manipulation of the phase of the lactate CH3 signal via J‐modulation. This is applied as a preparation experiment to the U‐FLARE imaging sequence. Phantom experiments are presented in which the quality of water and lipid suppression is established. Edited lactate images with a spatial resolution of 3 m̈L and total measuring time of 15.8 min are shown. These were obtained from a hemispherical ischemia in the gerbil brain. The images are compared with diffusion‐weighted water images.

Original languageEnglish
Pages (from-to)225-231
Number of pages7
JournalNMR in biomedicine
Issue number5
Publication statusPublished - Aug 1995
Externally publishedYes


  • NLA


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