A functional analysis-based approach to quantify upper limb impairment level in chronic stroke patients: A pilot study

Anne Schwarz, Giuseppe Averta*, Janne M. Veerbeek, Andreas R. Luft, Jeremia P.O. Held, Gaetano Valenza, Antonio Biechi, Matteo Bianchi

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

6 Citations (Scopus)

Abstract

The accurate assessment of upper limb motion impairment induced by stroke - which represents one of the primary causes of disability world-wide - is the first step to successfully monitor and guide patients' recovery. As of today, the majority of the procedures relies on clinical scales, which are mostly based on ordinal scaling, operator-dependent, and subject to floor and ceiling effects. In this work, we intend to overcome these limitations by proposing a novel approach to analytically evaluate the level of pathological movement coupling, based on the quantification of movement complexity. To this goal, we consider the variations of functional Principal Components applied to the reconstruction of joint angle trajectories of the upper limb during daily living task execution, and compared these variations between two conditions, i.e. the affected and non-affected arm. A Dissimilarity Index, which codifies the severity of the upper limb motor impairment with respect to the movement complexity of the non-affected arm, is then proposed. This methodology was validated as a proof of concept upon a set of four chronic stroke subjects with mild to moderate arm and hand impairments. As a first step, we evaluated whether the derived outcomes differentiate between the two conditions upon the whole data-set. Secondly, we exploited this concept to discern between different subjects and impairment levels. Results show that: i) differences in terms of movement variability between the affected and nonaffected upper limb are detectable and ii) different impairment profiles can be characterized for single subjects using the proposed approach. Although provisional, these results are very promising and suggest this approach as a basis ingredient for the definition of a novel, operator-independent, sensitive, intuitive and widely applicable scale for the evaluation of upper limb motion impairment.

Original languageEnglish
Title of host publication2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019
PublisherIEEE
Pages4198-4204
Number of pages7
ISBN (Electronic)9781538613115
DOIs
Publication statusPublished - Jul 2019
Event41st International Engineering in Medicine and Biology Conference, EMBC 2019: Biomedical Engineering Ranging from Wellness to Intensive Care Medicine - CityCube Berlin, Berlin, Germany
Duration: 23 Jul 201927 Jul 2019
Conference number: 41
https://embc.embs.org/2019/

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)1557-170X

Conference

Conference41st International Engineering in Medicine and Biology Conference, EMBC 2019
Abbreviated titleEMBC
CountryGermany
CityBerlin
Period23/07/1927/07/19
Internet address

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