A genetic analysis of brain volumes and IQ in children

Marieke van Leeuwen; Jiska S. Peper; Stéphanie Martine van den Berg; Rachel M. Brouwer; Hilleke E. Hulshoff Pol; Rene S. Kahn; Dorret I. Boomsma

doi:10.1016/j.intell.2008.10.005

A genetic analysis of brain volumes and IQ in children

Marieke van Leeuwen, Jiska S. Peper, Stéphanie Martine van den Berg, Rachel M. Brouwer, Hilleke E. Hulshoff Pol, Rene S. Kahn, Dorret I. Boomsma

Research output: Contribution to journal › Article › Academic › peer-review

36 Citations (Scopus)

11 Downloads (Pure)

Abstract

In a population-based sample of 112 nine-year old twin pairs, we investigated the association among total brain volume, gray matter and white matter volume, intelligence as assessed by the Raven IQ test, verbal comprehension, perceptual organization and perceptual speed as assessed by the Wechsler Intelligence Scale for Children-III. Phenotypic correlations between the brain volumes and intelligence traits ranged between .20 and .33. Processing speed and brain volume did not correlate. The relation between brain volume and intelligence was entirely explained by a common set of genes influencing both sets of phenotypes.

Original language	Undefined
Pages (from-to)	181-191
Number of pages	11
Journal	Intelligence: the future of computing
Volume	37
Issue number	2
DOIs	https://doi.org/10.1016/j.intell.2008.10.005
Publication status	Published - 2009

Keywords

IR-73344
METIS-261456

Access to Document

10.1016/j.intell.2008.10.005

Cite this

@article{6ecd0d98a63b4c5a9a7f315fcfcf1821,

title = "A genetic analysis of brain volumes and IQ in children",

abstract = "In a population-based sample of 112 nine-year old twin pairs, we investigated the association among total brain volume, gray matter and white matter volume, intelligence as assessed by the Raven IQ test, verbal comprehension, perceptual organization and perceptual speed as assessed by the Wechsler Intelligence Scale for Children-III. Phenotypic correlations between the brain volumes and intelligence traits ranged between .20 and .33. Processing speed and brain volume did not correlate. The relation between brain volume and intelligence was entirely explained by a common set of genes influencing both sets of phenotypes.",

keywords = "IR-73344, METIS-261456",

author = "{van Leeuwen}, Marieke and Peper, {Jiska S.} and {van den Berg}, {St{\'e}phanie Martine} and Brouwer, {Rachel M.} and {Hulshoff Pol}, {Hilleke E.} and Kahn, {Rene S.} and Boomsma, {Dorret I.}",

year = "2009",

doi = "10.1016/j.intell.2008.10.005",

language = "Undefined",

volume = "37",

pages = "181--191",

journal = "Intelligence: the future of computing",

issn = "1042-4296",

publisher = "Intelligence",

number = "2",

}

TY - JOUR

T1 - A genetic analysis of brain volumes and IQ in children

AU - van Leeuwen, Marieke

AU - Peper, Jiska S.

AU - van den Berg, Stéphanie Martine

AU - Brouwer, Rachel M.

AU - Hulshoff Pol, Hilleke E.

AU - Kahn, Rene S.

AU - Boomsma, Dorret I.

PY - 2009

Y1 - 2009

N2 - In a population-based sample of 112 nine-year old twin pairs, we investigated the association among total brain volume, gray matter and white matter volume, intelligence as assessed by the Raven IQ test, verbal comprehension, perceptual organization and perceptual speed as assessed by the Wechsler Intelligence Scale for Children-III. Phenotypic correlations between the brain volumes and intelligence traits ranged between .20 and .33. Processing speed and brain volume did not correlate. The relation between brain volume and intelligence was entirely explained by a common set of genes influencing both sets of phenotypes.

AB - In a population-based sample of 112 nine-year old twin pairs, we investigated the association among total brain volume, gray matter and white matter volume, intelligence as assessed by the Raven IQ test, verbal comprehension, perceptual organization and perceptual speed as assessed by the Wechsler Intelligence Scale for Children-III. Phenotypic correlations between the brain volumes and intelligence traits ranged between .20 and .33. Processing speed and brain volume did not correlate. The relation between brain volume and intelligence was entirely explained by a common set of genes influencing both sets of phenotypes.

KW - IR-73344

KW - METIS-261456

U2 - 10.1016/j.intell.2008.10.005

DO - 10.1016/j.intell.2008.10.005

M3 - Article

SN - 1042-4296

VL - 37

SP - 181

EP - 191

JO - Intelligence: the future of computing

JF - Intelligence: the future of computing

IS - 2

ER -