A Hemoperfusion Column Based on Activated Carbon Granules Coated with an Ultrathin Membrane of Cellulose Acetate

Johan Tijssen, Adriaan Bantjes, Albert W.J. van Doorn, Jan Feijen, Boudewijn van Dijk, Carel R. Vonk, Ido C. Dijkhuis

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Abstract

A hemoperfusion system has been developed which makes use of activated carbon encapsulated with cellulose acetate. Studies have revealed that there are no stagnant flow regions in the column, there i? minimal particle release and the coating is 30 Å thick. The relationships between pore size, pore volume and surface area have been examined. Twenty-five patients in grade IV coma have been treated with the column for treatment of drug overdose or agricultural chemical poisoning; the clinical course of one meprobamate-poisoned patient is described in detail.
Original languageEnglish
Pages (from-to)11-14
JournalArtificial organs
Volume3
Issue number1
DOIs
Publication statusPublished - 1979
EventTutzing Symposium on Hemoperfusion, Dialysate and Diafiltrate Purification 1978 - Tutzing, Germany
Duration: 11 Sep 197813 Sep 1978

Keywords

  • Poisoning
  • Cellulose acetate coating
  • Activated carbon
  • Hemoperfusion
  • IR-70650

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