A knowledge based advisory system for acid/base titrations in non-aqueous solvents

M. Bos, W.E. van der Linden

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    A computer program was developed that could advice on the choice of solvent and titrant for acid/base titrations in nonaqueous media. It is shown that the feasibility of a titration in a given solvent can be calculated from solvent properties and intrinsic acid/base properties of the sample components. A consistent set of properties for various solvents and a large number of acidic and basic compounds was calculated from literature data with the use of a genetic algorithm. Test results show that the system works well for titrations in various classes of solvents.
    Original languageUndefined
    Pages (from-to)201-211
    Number of pages11
    JournalAnalytica chimica acta
    Issue number332
    Publication statusPublished - 1996


    • METIS-106718
    • IR-12537

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