A lab-on-a-chip system integrated with subwavelength periodic patterned metal surfaces for sers-based molecular identification biosensing

Mingliang Jin, Lingling Shui, Cornelis Otto, Albert van den Berg, Edwin Carlen

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Abstract

We present a new lab-on-a-chip (LOC) analysis platform that is integrated with nanotextured surfaces with periodically spaced subwavelength nanogroove and nanopyramid structures with precisely defined pitch λg and separation gaps of ~2 nm spacing that form high density arrays of hot-spot scattering sites ideally suited for surface enhanced Raman scattering (SERS) and Raman spectroscopy using small sample volumes. The simple fabrication technique requires conventional lithography, wet anisotropic etching and a bonded polymer microfluidic layer. Measured Raman enhancement factors of G~106 from rhodamine 6G (R6G) on patterned Au surfaces with λg=200 nm are consistent with numerical calculations.
Original languageEnglish
Title of host publicationProceedings of the 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010
EditorsSabeth Verpoorte, Helen Andersson-Vahn, Jenny Emnéus, Nicole Pamme
PublisherThe Chemical and Biological Microsystems Society
Pages1250-1252
Number of pages3
ISBN (Electronic)978-0-9798064-3-8
ISBN (Print)978-1-6183906-2-2
Publication statusPublished - 3 Oct 2010
Event14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010 - Groningen, Netherlands
Duration: 3 Oct 20107 Oct 2010
Conference number: 14

Publication series

NameInternational Conference on Miniaterized Systems for Chemistry and Life Sciences : [proceedings]
PublisherThe Chemical and Biological Microsystems Society
Volume2010
ISSN (Print)1556-5904

Conference

Conference14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010
Abbreviated titleMicroTAS 2010
CountryNetherlands
CityGroningen
Period3/10/107/10/10

Keywords

  • surface enhanced Raman scattering
  • Plasmonics
  • Nanostructures
  • Lab-on-a-chip

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