A Method towards Automated Thrombolysis in Myocardial Infarction (TIMI) Frame Counting Using 3D Reconstruction

G.A. ten Brinke, Cornelis H. Slump, C.J. Storm, M.G. Stoel

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

    1 Citation (Scopus)
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    Coronary stenosis is often assessed using planar X-ray angiography while injecting contrast agent. The data obtained during the intervention can be used to assess coronary flow velocity by tracking the contrast agent. The contrast flow can be used to estimate the functional behavior of the coronary arteries using TIMI frame count (TFC). In this paper we propose and evaluate a method towards the automation of TFC. The method creates a two dimensional map of the contrast agent in which the opacification of the vessel centerline is plotted against time. This map is used to find the velocity of the contrast agent and subsequently the TFC. The vessel centerline is found using the Fast Marching Method to find the lowest cost path between the catheter point and the manually selected endpoint of the vessel. Results from 22 patients show that the algorithm is able to estimate TFC correctly in 13 of 22 cases within the intra observer error range of 5 frames compared to manual TFC.
    Original languageUndefined
    Title of host publicationComputers in Cardiology
    Place of PublicationUSA
    Number of pages4
    Publication statusPublished - 2009
    EventComputers in Cardiology 2009 - Park-City, Utah
    Duration: 13 Sep 200916 Sep 2009

    Publication series

    ISSN (Print)0276-6574


    ConferenceComputers in Cardiology 2009
    Other13-16 September 2009


    • METIS-265277
    • EWI-17388
    • IR-69863

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