A modelling approach demonstrating micromechanical changes in the tibial cemented interface due to in vivo service

Priyanka Srinivasan (Corresponding Author), Mark A. Miller, Nico Verdonschot, Kenneth A. Mann, Dennis Janssen

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)
30 Downloads (Pure)

Abstract

Post-operative changes in trabecular bone morphology at the cement-bone interface can vary depending on time in service. This study aims to investigate how micromotion and bone strains change at the tibial bone-cement interface before and after cementation. This work discusses whether the morphology of the post-mortem interface can be explained by studying changes in these mechanical quantities. Three post-mortem cement-bone interface specimens showing varying levels of bone resorption (minimal, extensive and intermediate) were selected for this study Using image segmentation techniques, masks of the post-mortem bone were dilated to fill up the mould spaces in the cement to obtain the immediately post-operative situation. Finite element (FE) models of the post-mortem and post-operative situation were created from these segmentation masks. Subsequent removal of the cement layer resulted in the pre-operative situation. FE micromotion and bone strains were analyzed for the interdigitated trabecular bone. For all specimens micromotion increased from the post-operative to the post-mortem models (distally, in specimen 1: 0.1 to 0.5 µm; specimen 2: 0.2 to 0.8 µm; specimen 3: 0.27 to 1.62 µm). Similarly bone strains were shown to increase from post-operative to post-mortem (distally, in specimen 1: −185 to −389 µε; specimen 2: −170 to −824 µε; specimen 3: −216 to −1024 µε). Post-mortem interdigitated bone was found to be strain shielded in comparison with supporting bone indicating that failure of bone would occur distal to the interface. These results indicate that stress shielding of interdigitated trabeculae is a plausible explanation for resorption patterns observed in post-mortem specimens.

Original languageEnglish
Pages (from-to)19-25
Number of pages7
JournalJournal of biomechanics
Volume56
DOIs
Publication statusPublished - 3 May 2017

Fingerprint

Bone
Bone and Bones
Bone Cements
Bone cement
Masks
Post and Core Technique
Cementation
Cements
Bone Resorption
Fungi
Image segmentation
Shielding
Cancellous Bone

Keywords

  • Bone strain
  • Bone–cement interface
  • Finite element analysis
  • Micromotion
  • Tibial loosening

Cite this

Srinivasan, Priyanka ; Miller, Mark A. ; Verdonschot, Nico ; Mann, Kenneth A. ; Janssen, Dennis. / A modelling approach demonstrating micromechanical changes in the tibial cemented interface due to in vivo service. In: Journal of biomechanics. 2017 ; Vol. 56. pp. 19-25.
@article{30c3fbca98dc46d2bc1aabaf32cc39f5,
title = "A modelling approach demonstrating micromechanical changes in the tibial cemented interface due to in vivo service",
abstract = "Post-operative changes in trabecular bone morphology at the cement-bone interface can vary depending on time in service. This study aims to investigate how micromotion and bone strains change at the tibial bone-cement interface before and after cementation. This work discusses whether the morphology of the post-mortem interface can be explained by studying changes in these mechanical quantities. Three post-mortem cement-bone interface specimens showing varying levels of bone resorption (minimal, extensive and intermediate) were selected for this study Using image segmentation techniques, masks of the post-mortem bone were dilated to fill up the mould spaces in the cement to obtain the immediately post-operative situation. Finite element (FE) models of the post-mortem and post-operative situation were created from these segmentation masks. Subsequent removal of the cement layer resulted in the pre-operative situation. FE micromotion and bone strains were analyzed for the interdigitated trabecular bone. For all specimens micromotion increased from the post-operative to the post-mortem models (distally, in specimen 1: 0.1 to 0.5 µm; specimen 2: 0.2 to 0.8 µm; specimen 3: 0.27 to 1.62 µm). Similarly bone strains were shown to increase from post-operative to post-mortem (distally, in specimen 1: −185 to −389 µε; specimen 2: −170 to −824 µε; specimen 3: −216 to −1024 µε). Post-mortem interdigitated bone was found to be strain shielded in comparison with supporting bone indicating that failure of bone would occur distal to the interface. These results indicate that stress shielding of interdigitated trabeculae is a plausible explanation for resorption patterns observed in post-mortem specimens.",
keywords = "Bone strain, Bone–cement interface, Finite element analysis, Micromotion, Tibial loosening",
author = "Priyanka Srinivasan and Miller, {Mark A.} and Nico Verdonschot and Mann, {Kenneth A.} and Dennis Janssen",
year = "2017",
month = "5",
day = "3",
doi = "10.1016/j.jbiomech.2017.02.017",
language = "English",
volume = "56",
pages = "19--25",
journal = "Journal of biomechanics",
issn = "0021-9290",
publisher = "Elsevier",

}

A modelling approach demonstrating micromechanical changes in the tibial cemented interface due to in vivo service. / Srinivasan, Priyanka (Corresponding Author); Miller, Mark A.; Verdonschot, Nico; Mann, Kenneth A.; Janssen, Dennis.

In: Journal of biomechanics, Vol. 56, 03.05.2017, p. 19-25.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - A modelling approach demonstrating micromechanical changes in the tibial cemented interface due to in vivo service

AU - Srinivasan, Priyanka

AU - Miller, Mark A.

AU - Verdonschot, Nico

AU - Mann, Kenneth A.

AU - Janssen, Dennis

PY - 2017/5/3

Y1 - 2017/5/3

N2 - Post-operative changes in trabecular bone morphology at the cement-bone interface can vary depending on time in service. This study aims to investigate how micromotion and bone strains change at the tibial bone-cement interface before and after cementation. This work discusses whether the morphology of the post-mortem interface can be explained by studying changes in these mechanical quantities. Three post-mortem cement-bone interface specimens showing varying levels of bone resorption (minimal, extensive and intermediate) were selected for this study Using image segmentation techniques, masks of the post-mortem bone were dilated to fill up the mould spaces in the cement to obtain the immediately post-operative situation. Finite element (FE) models of the post-mortem and post-operative situation were created from these segmentation masks. Subsequent removal of the cement layer resulted in the pre-operative situation. FE micromotion and bone strains were analyzed for the interdigitated trabecular bone. For all specimens micromotion increased from the post-operative to the post-mortem models (distally, in specimen 1: 0.1 to 0.5 µm; specimen 2: 0.2 to 0.8 µm; specimen 3: 0.27 to 1.62 µm). Similarly bone strains were shown to increase from post-operative to post-mortem (distally, in specimen 1: −185 to −389 µε; specimen 2: −170 to −824 µε; specimen 3: −216 to −1024 µε). Post-mortem interdigitated bone was found to be strain shielded in comparison with supporting bone indicating that failure of bone would occur distal to the interface. These results indicate that stress shielding of interdigitated trabeculae is a plausible explanation for resorption patterns observed in post-mortem specimens.

AB - Post-operative changes in trabecular bone morphology at the cement-bone interface can vary depending on time in service. This study aims to investigate how micromotion and bone strains change at the tibial bone-cement interface before and after cementation. This work discusses whether the morphology of the post-mortem interface can be explained by studying changes in these mechanical quantities. Three post-mortem cement-bone interface specimens showing varying levels of bone resorption (minimal, extensive and intermediate) were selected for this study Using image segmentation techniques, masks of the post-mortem bone were dilated to fill up the mould spaces in the cement to obtain the immediately post-operative situation. Finite element (FE) models of the post-mortem and post-operative situation were created from these segmentation masks. Subsequent removal of the cement layer resulted in the pre-operative situation. FE micromotion and bone strains were analyzed for the interdigitated trabecular bone. For all specimens micromotion increased from the post-operative to the post-mortem models (distally, in specimen 1: 0.1 to 0.5 µm; specimen 2: 0.2 to 0.8 µm; specimen 3: 0.27 to 1.62 µm). Similarly bone strains were shown to increase from post-operative to post-mortem (distally, in specimen 1: −185 to −389 µε; specimen 2: −170 to −824 µε; specimen 3: −216 to −1024 µε). Post-mortem interdigitated bone was found to be strain shielded in comparison with supporting bone indicating that failure of bone would occur distal to the interface. These results indicate that stress shielding of interdigitated trabeculae is a plausible explanation for resorption patterns observed in post-mortem specimens.

KW - Bone strain

KW - Bone–cement interface

KW - Finite element analysis

KW - Micromotion

KW - Tibial loosening

UR - http://www.scopus.com/inward/record.url?scp=85014678319&partnerID=8YFLogxK

U2 - 10.1016/j.jbiomech.2017.02.017

DO - 10.1016/j.jbiomech.2017.02.017

M3 - Article

VL - 56

SP - 19

EP - 25

JO - Journal of biomechanics

JF - Journal of biomechanics

SN - 0021-9290

ER -