Abstract
A non-porous C8 coated silicon pillar channel design is presented that allows the achievement of a high pressure and high efficiency operation for HPLC separations. Performing on-chip injection and detection and hence omitting the related dispersive sources, more than one million theoretical plates were obtained in non-retained conditions. The performance potential was also demonstrated by connecting the column to a commercial capillary HPLC system and injecting and detecting (UVVis) sample plugs off-chip.
| Original language | English |
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| Title of host publication | 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 |
| Pages | 626-628 |
| Number of pages | 3 |
| Publication status | Published - 2011 |
| Event | 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States Duration: 2 Oct 2011 → 6 Oct 2011 |
Conference
| Conference | 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 |
|---|---|
| Country/Territory | United States |
| City | Seattle, WA |
| Period | 2/10/11 → 6/10/11 |
Keywords
- Capillary chromatography
- High-pressure connection
- Pillar array
- Turn
- 22/4 OA procedure