A novel chromatography format for high efficiency separations

W. De Malsche; J. Op De Beeck; S. De Bruyne; H. Gardeniers; G. Desmet

A novel chromatography format for high efficiency separations

W. De Malsche
, J. Op De Beeck
, S. De Bruyne
, H. Gardeniers
, G. Desmet

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

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Abstract

A non-porous C8 coated silicon pillar channel design is presented that allows the achievement of a high pressure and high efficiency operation for HPLC separations. Performing on-chip injection and detection and hence omitting the related dispersive sources, more than one million theoretical plates were obtained in non-retained conditions. The performance potential was also demonstrated by connecting the column to a commercial capillary HPLC system and injecting and detecting (UVVis) sample plugs off-chip.

Original language	English
Title of host publication	15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Pages	626-628
Number of pages	3
Publication status	Published - 2011
Event	15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2011 - Seattle, United States Duration: 2 Oct 2011 → 6 Oct 2011 Conference number: 15 https://microtasconferences.org/microtas2011/

Conference

Conference	15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2011
Abbreviated title	MicroTAS
Country/Territory	United States
City	Seattle
Period	2/10/11 → 6/10/11
Internet address	https://microtasconferences.org/microtas2011/

Keywords

Capillary chromatography
High-pressure connection
Pillar array
Turn
22/4 OA procedure

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ArticleFinal published version, 1.75 MBLicence: Taverne

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title = "A novel chromatography format for high efficiency separations",

abstract = "A non-porous C8 coated silicon pillar channel design is presented that allows the achievement of a high pressure and high efficiency operation for HPLC separations. Performing on-chip injection and detection and hence omitting the related dispersive sources, more than one million theoretical plates were obtained in non-retained conditions. The performance potential was also demonstrated by connecting the column to a commercial capillary HPLC system and injecting and detecting (UVVis) sample plugs off-chip.",

keywords = "Capillary chromatography, High-pressure connection, Pillar array, Turn, 22/4 OA procedure",

author = "\{De Malsche\}, W. and \{Op De Beeck\}, J. and \{De Bruyne\}, S. and H. Gardeniers and G. Desmet",

year = "2011",

language = "English",

isbn = "9781618395955",

pages = "626--628",

booktitle = "15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011",

note = "15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2011, MicroTAS ; Conference date: 02-10-2011 Through 06-10-2011",

url = "https://microtasconferences.org/microtas2011/",

}

De Malsche, W, Op De Beeck, J, De Bruyne, S, Gardeniers, H & Desmet, G 2011, A novel chromatography format for high efficiency separations. in 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. pp. 626-628, 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2011, Seattle, Washington, United States, 2/10/11.

TY - GEN

T1 - A novel chromatography format for high efficiency separations

AU - De Malsche, W.

AU - Op De Beeck, J.

AU - De Bruyne, S.

AU - Gardeniers, H.

AU - Desmet, G.

N1 - Conference code: 15

PY - 2011

Y1 - 2011

N2 - A non-porous C8 coated silicon pillar channel design is presented that allows the achievement of a high pressure and high efficiency operation for HPLC separations. Performing on-chip injection and detection and hence omitting the related dispersive sources, more than one million theoretical plates were obtained in non-retained conditions. The performance potential was also demonstrated by connecting the column to a commercial capillary HPLC system and injecting and detecting (UVVis) sample plugs off-chip.

AB - A non-porous C8 coated silicon pillar channel design is presented that allows the achievement of a high pressure and high efficiency operation for HPLC separations. Performing on-chip injection and detection and hence omitting the related dispersive sources, more than one million theoretical plates were obtained in non-retained conditions. The performance potential was also demonstrated by connecting the column to a commercial capillary HPLC system and injecting and detecting (UVVis) sample plugs off-chip.

KW - Capillary chromatography

KW - High-pressure connection

KW - Pillar array

KW - Turn

KW - 22/4 OA procedure

UR - https://www.scopus.com/pages/publications/84883795987

M3 - Conference contribution

AN - SCOPUS:84883795987

SN - 9781618395955

SP - 626

EP - 628

BT - 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011

T2 - 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2011

Y2 - 2 October 2011 through 6 October 2011

ER -

A novel chromatography format for high efficiency separations

Abstract

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Keywords

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