A method to generate and control the permeability of polymersome membranes using mixtures of amphiphilic and stimuli-responsive boronic acid-containing block copolymers is reported. The latter block copolymers form phase-separated domains in the polymersomes, which can be dissolved by increasing the pH of the medium or by introducing sugar molecules that covalently bind to the boronic acid moieties.
- Stimuli-responsive materials
Kim, K. T., Cornelissen, J. J. L. M., Nolte, R. J. M., & van Hest, J. C. M. (2009). A polymersome nanoreactor with controllable permeability induced by stimuli-responsive blockcopolymers. Advanced materials, 21(27), 2787-2791. https://doi.org/10.1002/adma.200900300