A polymersome nanoreactor with controllable permeability induced by stimuli-responsive blockcopolymers

Kyoung Taek Kim, Jeroen Johannes Lambertus Maria Cornelissen, Roeland J.M. Nolte, Jan C.M. van Hest

Research output: Contribution to journalArticleAcademicpeer-review

242 Citations (Scopus)

Abstract

A method to generate and control the permeability of polymersome membranes using mixtures of amphiphilic and stimuli-responsive boronic acid-containing block copolymers is reported. The latter block copolymers form phase-separated domains in the polymersomes, which can be dissolved by increasing the pH of the medium or by introducing sugar molecules that covalently bind to the boronic acid moieties.
Original languageUndefined
Pages (from-to)2787-2791
Number of pages5
JournalAdvanced materials
Volume21
Issue number27
DOIs
Publication statusPublished - 2009

Keywords

  • Bioreactor
  • Nanoreactor
  • Self-Assembly
  • IR-77551
  • Polymersomes
  • METIS-263220
  • Stimuli-responsive materials

Cite this

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abstract = "A method to generate and control the permeability of polymersome membranes using mixtures of amphiphilic and stimuli-responsive boronic acid-containing block copolymers is reported. The latter block copolymers form phase-separated domains in the polymersomes, which can be dissolved by increasing the pH of the medium or by introducing sugar molecules that covalently bind to the boronic acid moieties.",
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volume = "21",
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A polymersome nanoreactor with controllable permeability induced by stimuli-responsive blockcopolymers. / Kim, Kyoung Taek; Cornelissen, Jeroen Johannes Lambertus Maria; Nolte, Roeland J.M.; van Hest, Jan C.M.

In: Advanced materials, Vol. 21, No. 27, 2009, p. 2787-2791.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - A polymersome nanoreactor with controllable permeability induced by stimuli-responsive blockcopolymers

AU - Kim, Kyoung Taek

AU - Cornelissen, Jeroen Johannes Lambertus Maria

AU - Nolte, Roeland J.M.

AU - van Hest, Jan C.M.

PY - 2009

Y1 - 2009

N2 - A method to generate and control the permeability of polymersome membranes using mixtures of amphiphilic and stimuli-responsive boronic acid-containing block copolymers is reported. The latter block copolymers form phase-separated domains in the polymersomes, which can be dissolved by increasing the pH of the medium or by introducing sugar molecules that covalently bind to the boronic acid moieties.

AB - A method to generate and control the permeability of polymersome membranes using mixtures of amphiphilic and stimuli-responsive boronic acid-containing block copolymers is reported. The latter block copolymers form phase-separated domains in the polymersomes, which can be dissolved by increasing the pH of the medium or by introducing sugar molecules that covalently bind to the boronic acid moieties.

KW - Bioreactor

KW - Nanoreactor

KW - Self-Assembly

KW - IR-77551

KW - Polymersomes

KW - METIS-263220

KW - Stimuli-responsive materials

U2 - 10.1002/adma.200900300

DO - 10.1002/adma.200900300

M3 - Article

VL - 21

SP - 2787

EP - 2791

JO - Advanced materials

JF - Advanced materials

SN - 0935-9648

IS - 27

ER -