A polymersome nanoreactor with controllable permeability induced by stimuli-responsive blockcopolymers

Kyoung Taek Kim, Jeroen Johannes Lambertus Maria Cornelissen, Roeland J.M. Nolte, Jan C.M. van Hest

Research output: Contribution to journalArticleAcademicpeer-review

265 Citations (Scopus)

Abstract

A method to generate and control the permeability of polymersome membranes using mixtures of amphiphilic and stimuli-responsive boronic acid-containing block copolymers is reported. The latter block copolymers form phase-separated domains in the polymersomes, which can be dissolved by increasing the pH of the medium or by introducing sugar molecules that covalently bind to the boronic acid moieties.
Original languageUndefined
Pages (from-to)2787-2791
Number of pages5
JournalAdvanced materials
Volume21
Issue number27
DOIs
Publication statusPublished - 2009

Keywords

  • Bioreactor
  • Nanoreactor
  • Self-Assembly
  • IR-77551
  • Polymersomes
  • METIS-263220
  • Stimuli-responsive materials

Cite this