A prefilled, ready-to-use, electrophoresis-based lab-on-a-chip device for monitoring ions in blood and urin

S.S. Staal; J. Floris; S.O. Lenk; M. Avilla Muñoz; D. Kohlheyer; J.C.T. Eijkel; A. van den Berg

A prefilled, ready-to-use, electrophoresis-based lab-on-a-chip device for monitoring ions in blood and urin

S.S. Staal, J. Floris, S.O. Lenk, M. Avilla Muñoz, D. Kohlheyer, J.C.T. Eijkel, A. van den Berg

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

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Abstract

We present the Medimate Multireader®, the first point-of-care Lab-on-a-Chip device based on Capillary Electrophoresis.We show that it is possible to analyze lithium in whole blood and sodium in urine, using a commercially viableMultireader that is suitable for self testing. In addition, we demonstrate the ability to detect creatinine using the sameplatform.

Original language	English
Title of host publication	14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010
Editors	Sabeth Verpoorte, Helen Andersson-Svath, Jenny Emnéus, Nicole Pamme
Place of Publication	San Diego
Publisher	The Chemical and Biological Microsystems Society
Pages	2107-2109
Number of pages	3
ISBN (Electronic)	978-0-9798064-3-8
ISBN (Print)	978-1-6183906-2-2
Publication status	Published - 7 Oct 2010
Event	14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, µTAS 2010 - Groningen, Netherlands Duration: 3 Oct 2010 → 7 Oct 2010 Conference number: 14

Publication series

Name	International Conference on Miniaterized Systems for Chemistry and Life Sciences : [proceedings]
Publisher	The Chemical and Biological Microsystems Society
Volume	2010
ISSN (Print)	1556-5904

Conference

Conference	14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, µTAS 2010
Abbreviated title	MicroTAS
Country	Netherlands
City	Groningen
Period	3/10/10 → 7/10/10

Keywords

Lab-on-a-chip
Point-of-care
Capillary electrophoresis
Conductivity detection
In vitro diagnostics
Lithium
Sodium
Creatinine

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Staal, S. S., Floris, J., Lenk, S. O., Avilla Muñoz, M., Kohlheyer, D., Eijkel, J. C. T., & van den Berg, A. (2010). A prefilled, ready-to-use, electrophoresis-based lab-on-a-chip device for monitoring ions in blood and urin. In S. Verpoorte, H. Andersson-Svath, J. Emnéus, & N. Pamme (Eds.), 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010 (pp. 2107-2109). (International Conference on Miniaterized Systems for Chemistry and Life Sciences : [proceedings]; Vol. 2010). San Diego: The Chemical and Biological Microsystems Society.

Staal, S.S. ; Floris, J. ; Lenk, S.O. ; Avilla Muñoz, M. ; Kohlheyer, D. ; Eijkel, J.C.T. ; van den Berg, A. / A prefilled, ready-to-use, electrophoresis-based lab-on-a-chip device for monitoring ions in blood and urin. 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010. editor / Sabeth Verpoorte ; Helen Andersson-Svath ; Jenny Emnéus ; Nicole Pamme. San Diego : The Chemical and Biological Microsystems Society, 2010. pp. 2107-2109 (International Conference on Miniaterized Systems for Chemistry and Life Sciences : [proceedings]).

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title = "A prefilled, ready-to-use, electrophoresis-based lab-on-a-chip device for monitoring ions in blood and urin",

abstract = "We present the Medimate Multireader{\circledR}, the first point-of-care Lab-on-a-Chip device based on Capillary Electrophoresis.We show that it is possible to analyze lithium in whole blood and sodium in urine, using a commercially viableMultireader that is suitable for self testing. In addition, we demonstrate the ability to detect creatinine using the sameplatform.",

keywords = "Lab-on-a-chip, Point-of-care, Capillary electrophoresis, Conductivity detection, In vitro diagnostics, Lithium, Sodium, Creatinine",

author = "S.S. Staal and J. Floris and S.O. Lenk and {Avilla Mu{\~n}oz}, M. and D. Kohlheyer and J.C.T. Eijkel and {van den Berg}, A.",

year = "2010",

month = "10",

day = "7",

language = "English",

isbn = "978-1-6183906-2-2",

series = "International Conference on Miniaterized Systems for Chemistry and Life Sciences : [proceedings]",

publisher = "The Chemical and Biological Microsystems Society",

pages = "2107--2109",

editor = "Sabeth Verpoorte and Helen Andersson-Svath and Jenny Emn{\'e}us and Nicole Pamme",

booktitle = "14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010",

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Staal, SS, Floris, J, Lenk, SO, Avilla Muñoz, M, Kohlheyer, D, Eijkel, JCT & van den Berg, A 2010, A prefilled, ready-to-use, electrophoresis-based lab-on-a-chip device for monitoring ions in blood and urin. in S Verpoorte, H Andersson-Svath, J Emnéus & N Pamme (eds), 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010. International Conference on Miniaterized Systems for Chemistry and Life Sciences : [proceedings], vol. 2010, The Chemical and Biological Microsystems Society, San Diego, pp. 2107-2109, 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, µTAS 2010, Groningen, Netherlands, 3/10/10.

A prefilled, ready-to-use, electrophoresis-based lab-on-a-chip device for monitoring ions in blood and urin. / Staal, S.S.; Floris, J.; Lenk, S.O.; Avilla Muñoz, M.; Kohlheyer, D.; Eijkel, J.C.T.; van den Berg, A.

14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010. ed. / Sabeth Verpoorte; Helen Andersson-Svath; Jenny Emnéus; Nicole Pamme. San Diego : The Chemical and Biological Microsystems Society, 2010. p. 2107-2109 (International Conference on Miniaterized Systems for Chemistry and Life Sciences : [proceedings]; Vol. 2010).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

TY - GEN

T1 - A prefilled, ready-to-use, electrophoresis-based lab-on-a-chip device for monitoring ions in blood and urin

AU - Staal, S.S.

AU - Floris, J.

AU - Lenk, S.O.

AU - Avilla Muñoz, M.

AU - Kohlheyer, D.

AU - Eijkel, J.C.T.

AU - van den Berg, A.

PY - 2010/10/7

Y1 - 2010/10/7

N2 - We present the Medimate Multireader®, the first point-of-care Lab-on-a-Chip device based on Capillary Electrophoresis.We show that it is possible to analyze lithium in whole blood and sodium in urine, using a commercially viableMultireader that is suitable for self testing. In addition, we demonstrate the ability to detect creatinine using the sameplatform.

AB - We present the Medimate Multireader®, the first point-of-care Lab-on-a-Chip device based on Capillary Electrophoresis.We show that it is possible to analyze lithium in whole blood and sodium in urine, using a commercially viableMultireader that is suitable for self testing. In addition, we demonstrate the ability to detect creatinine using the sameplatform.

KW - Lab-on-a-chip

KW - Point-of-care

KW - Capillary electrophoresis

KW - Conductivity detection

KW - In vitro diagnostics

KW - Lithium

KW - Sodium

KW - Creatinine

M3 - Conference contribution

SN - 978-1-6183906-2-2

T3 - International Conference on Miniaterized Systems for Chemistry and Life Sciences : [proceedings]

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BT - 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010

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A2 - Andersson-Svath, Helen

A2 - Emnéus, Jenny

A2 - Pamme, Nicole

PB - The Chemical and Biological Microsystems Society

CY - San Diego

ER -

Staal SS, Floris J, Lenk SO, Avilla Muñoz M, Kohlheyer D, Eijkel JCT et al. A prefilled, ready-to-use, electrophoresis-based lab-on-a-chip device for monitoring ions in blood and urin. In Verpoorte S, Andersson-Svath H, Emnéus J, Pamme N, editors, 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2010. San Diego: The Chemical and Biological Microsystems Society. 2010. p. 2107-2109. (International Conference on Miniaterized Systems for Chemistry and Life Sciences : [proceedings]).