A probabilistic and decision-theoretic approach to the management of infectious disease at the ICU

Peter J.F. Lucas*, Nicolette C. De Bruijn, Karin Schurink, Andy Hoepelman

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

84 Citations (Scopus)

Abstract

A probabilistic and decision-theoretic system that aims to assist clinicians in diagnosing and treating patients with pneumonia in the ICU is developed. Its probabilistic-network model includes temporal knowledge to diagnose pneumonia based on the likelihood of laryngotracheobronchial-tree colonization by pathogens, and symptoms and signs actually present in the patient. Optimal antimicrobial therapy is selected by balancing the expected efficacy of treatment.

Original languageEnglish
Pages (from-to)251-279
Number of pages29
JournalArtificial intelligence in medicine
Volume19
Issue number3
DOIs
Publication statusPublished - Jul 2000
Externally publishedYes

Keywords

  • Bayesian networks
  • Decision theory
  • Infectious diseases
  • Intensive care
  • Medical decision support
  • Probabilistic networks
  • Temporal probabilistic models
  • n/a OA procedure

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