A randomized controlled trial of an implantable 2-channel peroneal nerve stimulator on walking speed and activity in poststroke hemiplegia

A.I.R. Kottink, Anke I. Kottink, Hermanus J. Hermens, A.V. Nene, Martinus Johannes Bernardus Tenniglo, Hans E. van der Aa, H.P.J. Buschman, Maarten Joost IJzerman

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Abstract

Objective To determine the effect of a new implantable 2-channel peroneal nerve stimulator on walking speed and daily activities, in comparison with the usual treatment in chronic stroke survivors with a drop foot. Design Randomized controlled trial. Setting All subjects were measured 5 times in the gait laboratory. Participants Twenty-nine stroke survivors with chronic hemiplegia with drop foot who fulfill the predefined inclusion and exclusion criteria were included in the study. Intervention The intervention group received an implantable 2-channel peroneal nerve stimulator for correction of their drop foot. The control group continued using their conventional walking device, consisting of an ankle-foot orthosis, orthopedic shoes, or no device. Main Outcome Measures Walking speed, assessed both by a six-minute walk test (6MWT) and by using a 10-m walkway, was selected as primary outcome measure and activity monitoring data, consisting of percentage time spent on stepping, standing, and sitting/lying were selected as secondary outcome measure. Results Functional electric stimulation (FES) resulted in a 23% improvement of walking speed measured with the 6MWT, whereas the improvement in the control group was only 3% (P=.010). Comfortable walking speed measured on a 10-m walkway was also significantly improved in favor of FES (P=.038). The percentage time spent on stepping deteriorated with 3% in the intervention and 0.8% in control group, which was not statistically significant between both groups (P=.13). Conclusions The present study shows a clinically relevant effect of the implantable 2-channel peroneal nerve stimulator on walking speed in the sample of stroke survivors included in our study.
Original languageUndefined
Article number10.1016/j.apmr.2007.05.002
Pages (from-to)971-978
Number of pages8
JournalArchives of physical medicine and rehabilitation
Volume88
Issue numberLNCS4549/8
DOIs
Publication statusPublished - Aug 2007

Keywords

  • EWI-11142
  • IR-61945
  • METIS-241950
  • BSS-Electrical Neurostimulation

Cite this

@article{74522188d592402a8a13e1e53cbeb382,
title = "A randomized controlled trial of an implantable 2-channel peroneal nerve stimulator on walking speed and activity in poststroke hemiplegia",
abstract = "Objective To determine the effect of a new implantable 2-channel peroneal nerve stimulator on walking speed and daily activities, in comparison with the usual treatment in chronic stroke survivors with a drop foot. Design Randomized controlled trial. Setting All subjects were measured 5 times in the gait laboratory. Participants Twenty-nine stroke survivors with chronic hemiplegia with drop foot who fulfill the predefined inclusion and exclusion criteria were included in the study. Intervention The intervention group received an implantable 2-channel peroneal nerve stimulator for correction of their drop foot. The control group continued using their conventional walking device, consisting of an ankle-foot orthosis, orthopedic shoes, or no device. Main Outcome Measures Walking speed, assessed both by a six-minute walk test (6MWT) and by using a 10-m walkway, was selected as primary outcome measure and activity monitoring data, consisting of percentage time spent on stepping, standing, and sitting/lying were selected as secondary outcome measure. Results Functional electric stimulation (FES) resulted in a 23{\%} improvement of walking speed measured with the 6MWT, whereas the improvement in the control group was only 3{\%} (P=.010). Comfortable walking speed measured on a 10-m walkway was also significantly improved in favor of FES (P=.038). The percentage time spent on stepping deteriorated with 3{\%} in the intervention and 0.8{\%} in control group, which was not statistically significant between both groups (P=.13). Conclusions The present study shows a clinically relevant effect of the implantable 2-channel peroneal nerve stimulator on walking speed in the sample of stroke survivors included in our study.",
keywords = "EWI-11142, IR-61945, METIS-241950, BSS-Electrical Neurostimulation",
author = "A.I.R. Kottink and Kottink, {Anke I.} and Hermens, {Hermanus J.} and A.V. Nene and Tenniglo, {Martinus Johannes Bernardus} and {van der Aa}, {Hans E.} and H.P.J. Buschman and IJzerman, {Maarten Joost}",
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language = "Undefined",
volume = "88",
pages = "971--978",
journal = "Archives of physical medicine and rehabilitation",
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A randomized controlled trial of an implantable 2-channel peroneal nerve stimulator on walking speed and activity in poststroke hemiplegia. / Kottink, A.I.R.; Kottink, Anke I.; Hermens, Hermanus J.; Nene, A.V.; Tenniglo, Martinus Johannes Bernardus; van der Aa, Hans E.; Buschman, H.P.J.; IJzerman, Maarten Joost.

In: Archives of physical medicine and rehabilitation, Vol. 88, No. LNCS4549/8, 10.1016/j.apmr.2007.05.002, 08.2007, p. 971-978.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - A randomized controlled trial of an implantable 2-channel peroneal nerve stimulator on walking speed and activity in poststroke hemiplegia

AU - Kottink, A.I.R.

AU - Kottink, Anke I.

AU - Hermens, Hermanus J.

AU - Nene, A.V.

AU - Tenniglo, Martinus Johannes Bernardus

AU - van der Aa, Hans E.

AU - Buschman, H.P.J.

AU - IJzerman, Maarten Joost

N1 - 10.1016/j.apmr.2007.05.002

PY - 2007/8

Y1 - 2007/8

N2 - Objective To determine the effect of a new implantable 2-channel peroneal nerve stimulator on walking speed and daily activities, in comparison with the usual treatment in chronic stroke survivors with a drop foot. Design Randomized controlled trial. Setting All subjects were measured 5 times in the gait laboratory. Participants Twenty-nine stroke survivors with chronic hemiplegia with drop foot who fulfill the predefined inclusion and exclusion criteria were included in the study. Intervention The intervention group received an implantable 2-channel peroneal nerve stimulator for correction of their drop foot. The control group continued using their conventional walking device, consisting of an ankle-foot orthosis, orthopedic shoes, or no device. Main Outcome Measures Walking speed, assessed both by a six-minute walk test (6MWT) and by using a 10-m walkway, was selected as primary outcome measure and activity monitoring data, consisting of percentage time spent on stepping, standing, and sitting/lying were selected as secondary outcome measure. Results Functional electric stimulation (FES) resulted in a 23% improvement of walking speed measured with the 6MWT, whereas the improvement in the control group was only 3% (P=.010). Comfortable walking speed measured on a 10-m walkway was also significantly improved in favor of FES (P=.038). The percentage time spent on stepping deteriorated with 3% in the intervention and 0.8% in control group, which was not statistically significant between both groups (P=.13). Conclusions The present study shows a clinically relevant effect of the implantable 2-channel peroneal nerve stimulator on walking speed in the sample of stroke survivors included in our study.

AB - Objective To determine the effect of a new implantable 2-channel peroneal nerve stimulator on walking speed and daily activities, in comparison with the usual treatment in chronic stroke survivors with a drop foot. Design Randomized controlled trial. Setting All subjects were measured 5 times in the gait laboratory. Participants Twenty-nine stroke survivors with chronic hemiplegia with drop foot who fulfill the predefined inclusion and exclusion criteria were included in the study. Intervention The intervention group received an implantable 2-channel peroneal nerve stimulator for correction of their drop foot. The control group continued using their conventional walking device, consisting of an ankle-foot orthosis, orthopedic shoes, or no device. Main Outcome Measures Walking speed, assessed both by a six-minute walk test (6MWT) and by using a 10-m walkway, was selected as primary outcome measure and activity monitoring data, consisting of percentage time spent on stepping, standing, and sitting/lying were selected as secondary outcome measure. Results Functional electric stimulation (FES) resulted in a 23% improvement of walking speed measured with the 6MWT, whereas the improvement in the control group was only 3% (P=.010). Comfortable walking speed measured on a 10-m walkway was also significantly improved in favor of FES (P=.038). The percentage time spent on stepping deteriorated with 3% in the intervention and 0.8% in control group, which was not statistically significant between both groups (P=.13). Conclusions The present study shows a clinically relevant effect of the implantable 2-channel peroneal nerve stimulator on walking speed in the sample of stroke survivors included in our study.

KW - EWI-11142

KW - IR-61945

KW - METIS-241950

KW - BSS-Electrical Neurostimulation

U2 - 10.1016/j.apmr.2007.05.002

DO - 10.1016/j.apmr.2007.05.002

M3 - Article

VL - 88

SP - 971

EP - 978

JO - Archives of physical medicine and rehabilitation

JF - Archives of physical medicine and rehabilitation

SN - 0003-9993

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M1 - 10.1016/j.apmr.2007.05.002

ER -