TY - JOUR
T1 - A Robotic Urinary Bladder Enabling Volume Monitoring and Assisted Micturition
AU - Tamadon, Izadyar
AU - Ibrahimi, Michele
AU - Semproni, Federica
AU - Iacovacci, Veronica
AU - Menciassi, Arianna
N1 - Publisher Copyright:
© 2025 The Author(s). Advanced Intelligent Systems published by Wiley-VCH GmbH.
PY - 2025/10/17
Y1 - 2025/10/17
N2 - The urinary bladder is considered a highly complex organ, capable not only of storing urine but also of sensing intra-vesical volume and dynamically expanding and contracting. Consequently, fully replicating its functions following radical cystectomy remains a significant technological challenge. Hereinafter, an implantable robotic bladder is presented that can change shape and expand its internal volume up to 400 mL, based on the amount of urine collected from kidneys, and monitor the volume in real-time. It can apply on-demand mechanical compression to assist urination, by means of an origami-designed enclosure, coupled to miniaturized mechatronic components. In vitro characterization in a human phantom is demonstrated, and volume monitoring is validated following a realistic filling routine. The tests demonstrate successful expansions for collecting urine, with an average volume reconstruction error of 8.4 ± 6.1 mL, and then 99% of the volume is voided in less than 2 min. The work paves the way for developing active robotic solutions and reproducing bladder functions in patients with cancer and organ removal or impairment.
AB - The urinary bladder is considered a highly complex organ, capable not only of storing urine but also of sensing intra-vesical volume and dynamically expanding and contracting. Consequently, fully replicating its functions following radical cystectomy remains a significant technological challenge. Hereinafter, an implantable robotic bladder is presented that can change shape and expand its internal volume up to 400 mL, based on the amount of urine collected from kidneys, and monitor the volume in real-time. It can apply on-demand mechanical compression to assist urination, by means of an origami-designed enclosure, coupled to miniaturized mechatronic components. In vitro characterization in a human phantom is demonstrated, and volume monitoring is validated following a realistic filling routine. The tests demonstrate successful expansions for collecting urine, with an average volume reconstruction error of 8.4 ± 6.1 mL, and then 99% of the volume is voided in less than 2 min. The work paves the way for developing active robotic solutions and reproducing bladder functions in patients with cancer and organ removal or impairment.
KW - artificial organs
KW - impaired urinary bladder
KW - implantable devices
KW - inductance sensing
KW - robotic detrusor
UR - https://www.scopus.com/pages/publications/105019101204
U2 - 10.1002/aisy.202500516
DO - 10.1002/aisy.202500516
M3 - Article
SN - 2640-4567
JO - Advanced Intelligent Systems
JF - Advanced Intelligent Systems
M1 - e202500516
ER -