A route to anionic hydrophilic films of copolymers of l-leucine, l-aspartic acid and l-aspartic acid esters

W.L. Sederel, A. Bantjes, J. Feijen

Research output: Contribution to journalArticleAcademic

7 Citations (Scopus)
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Abstract

A series of copolymers of l-leucine and β-benzyl-l-aspartate [Leu/Asp(OBz)] covering the range 30–70 mol % of l-leucine, was synthesized by the N-carboxyanhydride (NCA) method. The copolymers were characterized by elemental analysis, infra-red spectroscopy and viscometry. For all compositions high molecular weight copolymers were prepared with excellent film-forming properties. Tercopolymers of l-leucine, β-benzyl-l-aspartate and β-methyl-l-aspartate [Leu/Asp(OBz)/Asp(OMe)] were obtained after an ester interchange reaction (conversion 85–95%) with the original copolymer systems. These tercopolymers were characterized by elemental analysis and i.r. spectroscopy. Films of the tercopolymers, cast from organic solvents, could be converted into hydrophilic films by saponification of the methyl ester groups using alkaline water/organic solvent media. The hydrophilic films, which will be further investigated for their use as haemodialysis membranes were characterized by potentiometric titration and i.r. spectroscopy.
Original languageEnglish
Pages (from-to)735-738
JournalPolymer
Volume16
Issue number10
DOIs
Publication statusPublished - 1975

Fingerprint

Aspartic Acid
Leucine
Esters
Copolymers
Acids
Organic solvents
Chemical analysis
Spectroscopy
Saponification
Viscosity measurement
Interchanges
Titration
Infrared spectroscopy
Molecular weight
Membranes
Water

Keywords

  • IR-68340

Cite this

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title = "A route to anionic hydrophilic films of copolymers of l-leucine, l-aspartic acid and l-aspartic acid esters",
abstract = "A series of copolymers of l-leucine and β-benzyl-l-aspartate [Leu/Asp(OBz)] covering the range 30–70 mol {\%} of l-leucine, was synthesized by the N-carboxyanhydride (NCA) method. The copolymers were characterized by elemental analysis, infra-red spectroscopy and viscometry. For all compositions high molecular weight copolymers were prepared with excellent film-forming properties. Tercopolymers of l-leucine, β-benzyl-l-aspartate and β-methyl-l-aspartate [Leu/Asp(OBz)/Asp(OMe)] were obtained after an ester interchange reaction (conversion 85–95{\%}) with the original copolymer systems. These tercopolymers were characterized by elemental analysis and i.r. spectroscopy. Films of the tercopolymers, cast from organic solvents, could be converted into hydrophilic films by saponification of the methyl ester groups using alkaline water/organic solvent media. The hydrophilic films, which will be further investigated for their use as haemodialysis membranes were characterized by potentiometric titration and i.r. spectroscopy.",
keywords = "IR-68340",
author = "W.L. Sederel and A. Bantjes and J. Feijen",
year = "1975",
doi = "10.1016/0032-3861(75)90190-1",
language = "English",
volume = "16",
pages = "735--738",
journal = "Polymer",
issn = "0032-3861",
publisher = "Elsevier",
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A route to anionic hydrophilic films of copolymers of l-leucine, l-aspartic acid and l-aspartic acid esters. / Sederel, W.L.; Bantjes, A.; Feijen, J.

In: Polymer, Vol. 16, No. 10, 1975, p. 735-738.

Research output: Contribution to journalArticleAcademic

TY - JOUR

T1 - A route to anionic hydrophilic films of copolymers of l-leucine, l-aspartic acid and l-aspartic acid esters

AU - Sederel, W.L.

AU - Bantjes, A.

AU - Feijen, J.

PY - 1975

Y1 - 1975

N2 - A series of copolymers of l-leucine and β-benzyl-l-aspartate [Leu/Asp(OBz)] covering the range 30–70 mol % of l-leucine, was synthesized by the N-carboxyanhydride (NCA) method. The copolymers were characterized by elemental analysis, infra-red spectroscopy and viscometry. For all compositions high molecular weight copolymers were prepared with excellent film-forming properties. Tercopolymers of l-leucine, β-benzyl-l-aspartate and β-methyl-l-aspartate [Leu/Asp(OBz)/Asp(OMe)] were obtained after an ester interchange reaction (conversion 85–95%) with the original copolymer systems. These tercopolymers were characterized by elemental analysis and i.r. spectroscopy. Films of the tercopolymers, cast from organic solvents, could be converted into hydrophilic films by saponification of the methyl ester groups using alkaline water/organic solvent media. The hydrophilic films, which will be further investigated for their use as haemodialysis membranes were characterized by potentiometric titration and i.r. spectroscopy.

AB - A series of copolymers of l-leucine and β-benzyl-l-aspartate [Leu/Asp(OBz)] covering the range 30–70 mol % of l-leucine, was synthesized by the N-carboxyanhydride (NCA) method. The copolymers were characterized by elemental analysis, infra-red spectroscopy and viscometry. For all compositions high molecular weight copolymers were prepared with excellent film-forming properties. Tercopolymers of l-leucine, β-benzyl-l-aspartate and β-methyl-l-aspartate [Leu/Asp(OBz)/Asp(OMe)] were obtained after an ester interchange reaction (conversion 85–95%) with the original copolymer systems. These tercopolymers were characterized by elemental analysis and i.r. spectroscopy. Films of the tercopolymers, cast from organic solvents, could be converted into hydrophilic films by saponification of the methyl ester groups using alkaline water/organic solvent media. The hydrophilic films, which will be further investigated for their use as haemodialysis membranes were characterized by potentiometric titration and i.r. spectroscopy.

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U2 - 10.1016/0032-3861(75)90190-1

DO - 10.1016/0032-3861(75)90190-1

M3 - Article

VL - 16

SP - 735

EP - 738

JO - Polymer

JF - Polymer

SN - 0032-3861

IS - 10

ER -