A Supramolecular System for the Electrochemically Controlled Release of Cells

Q. An; J. Brinkmann; Jurriaan Huskens; Sven Krabbenborg; Jan de Boer; Pascal Jonkheijm

doi:10.1002/anie.201205651

A Supramolecular System for the Electrochemically Controlled Release of Cells

Q. An, J. Brinkmann, Jurriaan Huskens, Sven Krabbenborg, Jan de Boer, Pascal Jonkheijm

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Please release me: Electrochemically activated cell release is achieved using a redox-active supramolecular complex. Host molecule CB[8] (green) links surface-bound viologen (purple) with solution-exposed RGD peptides (red). Electrochemical reduction dissociates the complex, releases the peptides, and thus releases the cells from the substrates. This supramolecular strategy is also applicable to microelectrodes.

Original language	English
Pages (from-to)	12233-12237
Journal	Angewandte Chemie (international edition)
Volume	51
Issue number	49
DOIs	https://doi.org/10.1002/anie.201205651
Publication status	Published - 4 Nov 2012

Keywords

IR-82127
METIS-289077

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10.1002/anie.201205651

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abstract = "Please release me: Electrochemically activated cell release is achieved using a redox-active supramolecular complex. Host molecule CB[8] (green) links surface-bound viologen (purple) with solution-exposed RGD peptides (red). Electrochemical reduction dissociates the complex, releases the peptides, and thus releases the cells from the substrates. This supramolecular strategy is also applicable to microelectrodes.",

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author = "Q. An and J. Brinkmann and Jurriaan Huskens and Sven Krabbenborg and {de Boer}, Jan and Pascal Jonkheijm",

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AU - An, Q.

AU - Brinkmann, J.

AU - Huskens, Jurriaan

AU - Krabbenborg, Sven

AU - de Boer, Jan

AU - Jonkheijm, Pascal

PY - 2012/11/4

Y1 - 2012/11/4

N2 - Please release me: Electrochemically activated cell release is achieved using a redox-active supramolecular complex. Host molecule CB[8] (green) links surface-bound viologen (purple) with solution-exposed RGD peptides (red). Electrochemical reduction dissociates the complex, releases the peptides, and thus releases the cells from the substrates. This supramolecular strategy is also applicable to microelectrodes.

AB - Please release me: Electrochemically activated cell release is achieved using a redox-active supramolecular complex. Host molecule CB[8] (green) links surface-bound viologen (purple) with solution-exposed RGD peptides (red). Electrochemical reduction dissociates the complex, releases the peptides, and thus releases the cells from the substrates. This supramolecular strategy is also applicable to microelectrodes.

KW - IR-82127

KW - METIS-289077

U2 - 10.1002/anie.201205651

DO - 10.1002/anie.201205651

M3 - Article

SN - 1433-7851

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SP - 12233

EP - 12237

JO - Angewandte Chemie (international edition)

JF - Angewandte Chemie (international edition)

IS - 49

ER -

A Supramolecular System for the Electrochemically Controlled Release of Cells

Abstract

Keywords

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