A vanishing lesion in the temporal lobe associated with schizophrenialike psychosis and catatonia

Kuan H. Kho*, Nicoletta M.J. Van Veelen, Lucas J. Beerepoot, Iris E.C. Sommer

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)


OBJECTIVE: To present the case of a patient with hallucinations and psychotic symptoms that co-occurs with a temporary lesion in the left posterior temporal lobe. BACKGROUND: Psychosis and auditory hallucinations are characteristic features of schizophrenia, but may also complicate many somatic diseases. Current functional imaging studies suggest a role of the temporal lobes. METHOD: We describe a patient who initially presented with schizophrenialike psychotic symptoms at an age of 23. She did not respond to antipsychotic medication and developed severe medication-resistant catatonia. RESULTS: Magnetic resonance imaging studies revealed an opaque left temporal lesion that could not be diagnosed otherwise. Electroconvulsive therapy led to remission of her catatonic and psychotic symptoms. After clinical remission, the temporal lesion had vanished. CONCLUSIONS: The longitudinal association between the lesion and the occurrence and disappearance of psychosis supports current theories on the role of the left temporal lobe in psychosis.

Original languageEnglish
Pages (from-to)232-234
Number of pages3
JournalCognitive and Behavioral Neurology
Issue number4
Publication statusPublished - Dec 2007
Externally publishedYes


  • Auditory hallucinations
  • Catatonia
  • ECT
  • Language
  • Neuropsychiatry
  • Psychosis
  • Temporal lobe
  • Transient brain lesion


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