ABO incompatibility and RhIG immunoprophylaxis protect against non-D alloimmunization by pregnancy

Carolien Zwiers, Joke M. Koelewijn, Lisa Vermij, Joost van Sambeeck, Dick Oepkes, Masja de Haas, C. Ellen van der Schoot

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Hemolytic disease of the fetus and newborn (HDFN) is a serious pregnancy complication, caused by maternal antibodies against fetal red blood cell (RBC) antigens. These antibodies may provoke fetal hemolysis, resulting in fetal anemia, hydrops, and even death if left untreated.1,2 HDFN is most frequently caused by antibodies with anti-D specificity, followed by anti-K, anti-c, anti-E, other Rh antibodies, or exceptionally, anti-Fy (Duffy) or anti-Jk (Kidd).
Original languageEnglish
Pages (from-to)1611-1617
JournalTransfusion
Volume58
Issue number7
Early online date6 Apr 2018
DOIs
Publication statusPublished - 1 Jul 2018

Fingerprint

Pregnancy
Antibody
Fetal Erythroblastosis
Antibodies
Fetus
Hydrops Fetalis
Red Blood Cells
Pregnancy Complications
Hemolysis
Complications
Fetal Blood
Specificity
Anemia
Erythrocytes
Mothers
Antigens

Keywords

  • UT-Hybrid-D
  • Immunoprophylaxis
  • ABO incompatibility
  • Hemolytic disease of the fetus and newborn

Cite this

Zwiers, C., Koelewijn, J. M., Vermij, L., van Sambeeck, J., Oepkes, D., de Haas, M., & van der Schoot, C. E. (2018). ABO incompatibility and RhIG immunoprophylaxis protect against non-D alloimmunization by pregnancy. Transfusion, 58(7), 1611-1617. https://doi.org/10.1111/trf.14606
Zwiers, Carolien ; Koelewijn, Joke M. ; Vermij, Lisa ; van Sambeeck, Joost ; Oepkes, Dick ; de Haas, Masja ; van der Schoot, C. Ellen. / ABO incompatibility and RhIG immunoprophylaxis protect against non-D alloimmunization by pregnancy. In: Transfusion. 2018 ; Vol. 58, No. 7. pp. 1611-1617.
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abstract = "Hemolytic disease of the fetus and newborn (HDFN) is a serious pregnancy complication, caused by maternal antibodies against fetal red blood cell (RBC) antigens. These antibodies may provoke fetal hemolysis, resulting in fetal anemia, hydrops, and even death if left untreated.1,2 HDFN is most frequently caused by antibodies with anti-D specificity, followed by anti-K, anti-c, anti-E, other Rh antibodies, or exceptionally, anti-Fy (Duffy) or anti-Jk (Kidd).",
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author = "Carolien Zwiers and Koelewijn, {Joke M.} and Lisa Vermij and {van Sambeeck}, Joost and Dick Oepkes and {de Haas}, Masja and {van der Schoot}, {C. Ellen}",
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Zwiers, C, Koelewijn, JM, Vermij, L, van Sambeeck, J, Oepkes, D, de Haas, M & van der Schoot, CE 2018, 'ABO incompatibility and RhIG immunoprophylaxis protect against non-D alloimmunization by pregnancy' Transfusion, vol. 58, no. 7, pp. 1611-1617. https://doi.org/10.1111/trf.14606

ABO incompatibility and RhIG immunoprophylaxis protect against non-D alloimmunization by pregnancy. / Zwiers, Carolien; Koelewijn, Joke M.; Vermij, Lisa; van Sambeeck, Joost; Oepkes, Dick; de Haas, Masja; van der Schoot, C. Ellen.

In: Transfusion, Vol. 58, No. 7, 01.07.2018, p. 1611-1617.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Zwiers, Carolien

AU - Koelewijn, Joke M.

AU - Vermij, Lisa

AU - van Sambeeck, Joost

AU - Oepkes, Dick

AU - de Haas, Masja

AU - van der Schoot, C. Ellen

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KW - UT-Hybrid-D

KW - Immunoprophylaxis

KW - ABO incompatibility

KW - Hemolytic disease of the fetus and newborn

U2 - 10.1111/trf.14606

DO - 10.1111/trf.14606

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