Acceptance and commitment therapy as a web-based intervention for depressive symptoms: randomised controlled trial

Wendy Theresia Maria Pots, M. Fledderus, Petrus Antonius Maria Meulenbeek, Peter M. ten Klooster, Karlein Maria Gertrudis Schreurs, Ernst Thomas Bohlmeijer

Research output: Contribution to journalArticleAcademicpeer-review

32 Citations (Scopus)


Background: Depression is a highly prevalent disorder, causing a large burden of disease and substantial economic costs. Web-based self-help interventions seem promising in promoting mental health. Aims: To compare the efficacy of a guided web-based intervention based on acceptance and commitment therapy (ACT) with an active control (expressive writing) and a waiting-list control condition (Netherlands Trial Register NTR1296). Method: Adults with depressive symptoms from the general population were randomised to ACT (n = 82), expressive writing (n = 67) or waiting-list control (n = 87). The main outcome was reduction in depressive symptoms assessed with the Center for Epidemiological Studies - Depression scale. Results: Significant reductions in depressive symptoms were found following the ACT intervention, compared with the control group (Cohen's d = 0.56) and the expressive writing intervention (d = 0.36). The effects were sustained at 6-month and 12-month follow-up. Conclusions: Acceptance and commitment therapy as a web-based public mental health intervention for adults with depressive symptoms can be effective and applicable
Original languageEnglish
Pages (from-to)69-77
JournalBritish journal of psychiatry
Issue number1
Publication statusPublished - 24 Jul 2015



  • IR-96661
  • METIS-311075

Cite this