Accurate EM-TV Algorithm in PET with Low SNR

Alex Sawatzky, Christoph Brune, Frank Wübbeling, Thomas Kosters, Klaus Schäfers*, Burger Martin

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

91 Citations (Scopus)


PET measurements of tracers with a lower dose rate or short radioactive half life sutTer from extremely low SNRs. In these cases standard reconstmction methods (OSEM, EM, filtered backprojection) deliver unsatisfactory and noisy results. Here, we propose to introduce nonlinear variational methods into the reconstruction process to make an efficient use of a-priori information and to attain improved imaging results. We illustrate our technique by evaluating cardiac H2150 measurements. The general approach can also be used for other specific goals allowing to incorporate a-priori information about the solution with Poisson distributed data.

Original languageEnglish
Title of host publication2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008
Number of pages5
Publication statusPublished - 1 Dec 2008
Externally publishedYes
EventIEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2008 - Maritim Hotel and Internationales Congress Ctr., Dresden, Germany
Duration: 19 Oct 200825 Oct 2008

Publication series

NameIEEE Nuclear Science Symposium Conference Record
ISSN (Print)1095-7863


ConferenceIEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2008
Abbreviated titleNSS/MIC
Internet address


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