To decrease NOx emissions from combustion systems, lean premixed combustion is used. A disadvantage is the higher sensitivity to combustion instabilities, leading to increased sound pressure levels in the combustor and resulting in an increased excitation of the surrounding structure: the liner. This causes fatigue, which limits the lifetime of the combustor. This paper presents a joint experimental and numerical investigation of this acoustoelastic interaction problem for frequencies up to 1 kHz. To study this problem experimentally, a test setup has been built consisting of a single burner, 500 kW, 5 bar combustion system. The thin structure (liner) is contained in a thick pressure vessel with optical access for a traversing laser vibrometer system to measure the vibration levels of the liner. The acoustic excitation of the liner is measured using pressure sensors measuring the acoustic pressures inside the combustion chamber. For the numerical model, the finite element method with full coupling between structural vibration and acoustics is used. The flame is modeled as an acoustic volume source corresponding to a heat release rate that is frequency independent. The temperature distribution is taken from a Reynolds averaged Navier Stokes (RaNS) computational fluid dynamics (CFD) simulation. Results show very good agreement between predicted and measured acoustic pressure levels. The predicted and measured vibration levels also match fairly well.