Additive manufacturing of polyhydroxyalkanoates (PHAs) biopolymers: Materials, printing techniques, and applications

Mehrshad Mehrpouya* (Corresponding Author), Henri Vahabi, Massimiliano Barletta, Pascal Laheurte, Valérie Langlois

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

70 Citations (Scopus)
390 Downloads (Pure)


Additive manufacturing (AM) is recently imposing as a fast, reliable, and highly flexible solution to process various materials, that range from metals to polymers, to achieve a broad variety of customized end-goods without involving the injection molding process. The employment of biomaterials is of utmost relevance as the environmental footprint of the process and, consequently, of the end-goods is significantly decreased. Additive manufacturing can provide, in particular, an all-in-one platform to fabricate complex-shaped biobased items such as bone implants or biomedical devices, that would be, otherwise, extremely troublesome and costly to achieve. Polyhydroxyalkanoates (PHAs) is an emerging class of biobased and biodegradable polymeric materials achievable by fermentation from bacteria. There are some promising scientific and technical reports on the manufacturing of several commodities in PHAs by additive manufacturing. However, many challenges must still be faced in order to expand further the use of PHAs. In this framework, the present work reviews and classifies the relevant papers focused on the design and development of PHAs for different 3D printing techniques and overviews the most recent applications of this approach.

Original languageEnglish
Article number112216
Number of pages13
JournalMaterials Science and Engineering C: Materials for Biological Applications
Early online date29 May 2021
Publication statusPublished - Aug 2021


  • 3D printing
  • Additive manufacturing
  • Biobased polymers
  • Polyhydroxyalkanoates (PHAs)
  • UT-Hybrid-D


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