Advancing Tissue Engineering: A Tale of Nano-, Micro-, and Macroscale Integration

Jeroen Christianus Hermanus Leijten, Jeroen Rouwkema, Y.S. Zhang, A. Nasajpour, M.R. Dokmeci, A. Khademhosseini

Research output: Contribution to journalArticleAcademicpeer-review

60 Citations (Scopus)
12 Downloads (Pure)


Tissue engineering has the potential to revolutionize the health care industry. Delivering on this promise requires the generation of efficient, controllable and predictable implants. The integration of nano- and microtechnologies into macroscale regenerative biomaterials plays an essential role in the generation of such implants, by enabling spatiotemporal control of the cellular microenvironment. Here we review the role, function and progress of a wide range of nano- and microtechnologies that are driving the advancements in the field of tissue engineering.
Original languageEnglish
Pages (from-to)2130-2145
Number of pages16
Issue number16
Publication statusPublished - 2016


  • IR-100681
  • METIS-316991
  • 22/4 OA procedure


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