Age-specific incidence and treatment patterns of head and neck cancer in the Netherlands: A cohort study

G.B. Halmos (Corresponding Author), L. Bras, S. Siesling, B.F.A.M. van der Laan, J.A. Langendijk, B.A.C. van Dijk

Research output: Contribution to journalArticleAcademicpeer-review

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Objectives: To explore the incidence and treatment pattern of head and neck cancer in different age groups. Design: Cohort study.

Setting: Netherlands Cancer Registry. Participants: All new primary head and neck cancer cases diagnosed between 2010 and 2014 were included and categorised into different age groups.

Main outcome measures: Tumour site, stage, treatment modality, location of diagnosis and treatment.

Results: The study population was composed of 11 558 tumours. Oral cancer was the most common primary site (31%), followed by laryngeal (25%) and oropharyngeal cancer (22%). Ninety-six per cent of the entire study population was diagnosed and/or treated in a certified head and neck oncology centre which was lower in the 80+ population (92%). Multimodality treatment was less frequently applied with increasing age (eg oral cavity: 17% in 80+ vs 34% in 60-; P < .001). The percentage of patients not receiving tumour-directed treatment increased with age (eg oropharyngeal cancer: 25% in 80+ vs 6% in 80-; P < .001).

Conclusions: This study confirms that less multimodal and tumour-directed treatment is applied with the increasing age of head and neck cancer patients.

Original languageEnglish
Pages (from-to)317-324
JournalClinical otolaryngology
Issue number1
Publication statusPublished - 1 Feb 2018


  • UT-Hybrid-D
  • Elderly
  • Head and neck cancer
  • Incidence
  • Treatment
  • Age
  • 2023 OA procedure


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