Airflow from nasal pulse oximetry in the screening of obstructive sleep apnea

Xenia L.R. Hoppenbrouwer, T. Fabius, M. Eijsvogel, F. de Jongh, A. Garde

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

    1 Citation (Scopus)

    Abstract

    Obstructive Sleep Apnea (OSA) is recognized as an increasing health risk, leading to daytime sleepiness and various medical conditions, such as hypertension and heart failure. Polysomnography (PSG), the gold standard to diagnose OSA, is a resource-intensive and expensive investigation confined to the hospital.Portable home monitoring, i.e. pulse oximetry, may become an acceptable OSA screening method. The novel nasal pulse oximeter sensor (Xhale Alar) adds the possibility of combining pulse oximetry (SpO2) with airflow analysis by an integrated thermistor, which might increase the diagnostic accuracy.In the Alar pilot study, 39 adults were measured during an overnight PSG recording together with the Alar sensor. This study aims to investigate the additional value of an airflow signal compared to SpO2 analysis in OSA screening. Both time and spectral features were extracted from SpO2 and airflow signals recorded with the Alar sensor. Leave one out cross-validation was used to develop Random Forest models in screening for apnea-hypopnea index (AHI) thresholds 5 and 10. Using both AHI ≥ 5 and AHI ≥ 10 as the diagnostic cutoff, the airflow signal shows respectively an AUC of 89% and 80% compared to 78% and 77% with SpO2 analysis, showing a higher performance using an airflow signal in screening adults for OSA.

    Original languageEnglish
    Title of host publication2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
    Place of PublicationPiscataway, NJ
    PublisherIEEE
    Pages2572-2575
    Number of pages4
    ISBN (Electronic)978-1-5386-1311-5
    ISBN (Print)978-1-5386-1312-2
    DOIs
    Publication statusPublished - 7 Oct 2019
    Event41st International Engineering in Medicine and Biology Conference, EMBC 2019: Biomedical Engineering Ranging from Wellness to Intensive Care Medicine - CityCube Berlin, Berlin, Germany
    Duration: 23 Jul 201927 Jul 2019
    Conference number: 41
    https://embc.embs.org/2019/

    Publication series

    NameProceedings Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
    PublisherIEEE
    Volume2019
    ISSN (Print)1557-170X
    ISSN (Electronic)1558-4615

    Conference

    Conference41st International Engineering in Medicine and Biology Conference, EMBC 2019
    Abbreviated titleEMBC
    CountryGermany
    CityBerlin
    Period23/07/1927/07/19
    Internet address

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