Al2O3 Microresonator Based Passive and Active Biosensors

Michiel De Goede, Lantian Chang, Meindert Dijkstra, Raquel Obregon, Javier Ramon-Azcon, Elena Martinez, Laura Padilla, Jaume Adan, Francesc Mitjans, Sonia M. Garcia-Blanco

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

1 Citation (Scopus)
7 Downloads (Pure)

Abstract

Al2O3 microresonators were realized for sensing applications of both passive and active devices. Passive microring resonators exhibited quality factors up to 3.2×105 in air. A bulk refractive index sensitivity of 100 nm/RIU was demonstrated together with a limit of detection of 10-6 RIU. Functionalizing their surface allowed for the label-free detection of the biomarker rhS100A4 from urine with a limit of detection of 3 nM. Furthermore, single-mode Al2O3:Yb3+ microdisk lasers were realized that could operate in an aqueous environment. Upon varying the bulk refractive index their lasing wavelength could be tuned with a sensitivity of 20 nm/RIU and a LOD of 3×10-6 RIU.

Original languageEnglish
Title of host publication2018 20th International Conference on Transparent Optical Networks, ICTON 2018
PublisherIEEE Computer Society
Volume2018-July
ISBN (Electronic)9781538666043
ISBN (Print)9781538666043
DOIs
Publication statusPublished - 26 Sep 2018

Publication series

NameInternational Conference on Transparent Optical Networks
Volume2018-July

Fingerprint

Biosensors
Refractive index
Biomarkers
Laser modes
Labels
Resonators
Wavelength
Lasers
Air

Keywords

  • aluminium oxide
  • microresonator
  • optical sensing.
  • ytterbium

Cite this

De Goede, M., Chang, L., Dijkstra, M., Obregon, R., Ramon-Azcon, J., Martinez, E., ... Garcia-Blanco, S. M. (2018). Al2O3 Microresonator Based Passive and Active Biosensors. In 2018 20th International Conference on Transparent Optical Networks, ICTON 2018 (Vol. 2018-July). [8473820] (International Conference on Transparent Optical Networks; Vol. 2018-July). IEEE Computer Society. https://doi.org/10.1109/ICTON.2018.8473820
De Goede, Michiel ; Chang, Lantian ; Dijkstra, Meindert ; Obregon, Raquel ; Ramon-Azcon, Javier ; Martinez, Elena ; Padilla, Laura ; Adan, Jaume ; Mitjans, Francesc ; Garcia-Blanco, Sonia M. / Al2O3 Microresonator Based Passive and Active Biosensors. 2018 20th International Conference on Transparent Optical Networks, ICTON 2018. Vol. 2018-July IEEE Computer Society, 2018. (International Conference on Transparent Optical Networks).
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De Goede, M, Chang, L, Dijkstra, M, Obregon, R, Ramon-Azcon, J, Martinez, E, Padilla, L, Adan, J, Mitjans, F & Garcia-Blanco, SM 2018, Al2O3 Microresonator Based Passive and Active Biosensors. in 2018 20th International Conference on Transparent Optical Networks, ICTON 2018. vol. 2018-July, 8473820, International Conference on Transparent Optical Networks, vol. 2018-July, IEEE Computer Society. https://doi.org/10.1109/ICTON.2018.8473820

Al2O3 Microresonator Based Passive and Active Biosensors. / De Goede, Michiel; Chang, Lantian; Dijkstra, Meindert; Obregon, Raquel; Ramon-Azcon, Javier; Martinez, Elena; Padilla, Laura; Adan, Jaume; Mitjans, Francesc; Garcia-Blanco, Sonia M.

2018 20th International Conference on Transparent Optical Networks, ICTON 2018. Vol. 2018-July IEEE Computer Society, 2018. 8473820 (International Conference on Transparent Optical Networks; Vol. 2018-July).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

TY - CHAP

T1 - Al2O3 Microresonator Based Passive and Active Biosensors

AU - De Goede, Michiel

AU - Chang, Lantian

AU - Dijkstra, Meindert

AU - Obregon, Raquel

AU - Ramon-Azcon, Javier

AU - Martinez, Elena

AU - Padilla, Laura

AU - Adan, Jaume

AU - Mitjans, Francesc

AU - Garcia-Blanco, Sonia M.

PY - 2018/9/26

Y1 - 2018/9/26

N2 - Al2O3 microresonators were realized for sensing applications of both passive and active devices. Passive microring resonators exhibited quality factors up to 3.2×105 in air. A bulk refractive index sensitivity of 100 nm/RIU was demonstrated together with a limit of detection of 10-6 RIU. Functionalizing their surface allowed for the label-free detection of the biomarker rhS100A4 from urine with a limit of detection of 3 nM. Furthermore, single-mode Al2O3:Yb3+ microdisk lasers were realized that could operate in an aqueous environment. Upon varying the bulk refractive index their lasing wavelength could be tuned with a sensitivity of 20 nm/RIU and a LOD of 3×10-6 RIU.

AB - Al2O3 microresonators were realized for sensing applications of both passive and active devices. Passive microring resonators exhibited quality factors up to 3.2×105 in air. A bulk refractive index sensitivity of 100 nm/RIU was demonstrated together with a limit of detection of 10-6 RIU. Functionalizing their surface allowed for the label-free detection of the biomarker rhS100A4 from urine with a limit of detection of 3 nM. Furthermore, single-mode Al2O3:Yb3+ microdisk lasers were realized that could operate in an aqueous environment. Upon varying the bulk refractive index their lasing wavelength could be tuned with a sensitivity of 20 nm/RIU and a LOD of 3×10-6 RIU.

KW - aluminium oxide

KW - microresonator

KW - optical sensing.

KW - ytterbium

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UR - http://www.mendeley.com/research/al2o3-microresonator-based-passive-active-biosensors

U2 - 10.1109/ICTON.2018.8473820

DO - 10.1109/ICTON.2018.8473820

M3 - Chapter

SN - 9781538666043

VL - 2018-July

T3 - International Conference on Transparent Optical Networks

BT - 2018 20th International Conference on Transparent Optical Networks, ICTON 2018

PB - IEEE Computer Society

ER -

De Goede M, Chang L, Dijkstra M, Obregon R, Ramon-Azcon J, Martinez E et al. Al2O3 Microresonator Based Passive and Active Biosensors. In 2018 20th International Conference on Transparent Optical Networks, ICTON 2018. Vol. 2018-July. IEEE Computer Society. 2018. 8473820. (International Conference on Transparent Optical Networks). https://doi.org/10.1109/ICTON.2018.8473820